H7N9 Bird Flu Virus - Biotech, Pharma and Life Science Channel

06:15 EST 2nd March 2015 | BioPortfolio

Avian influenza A H7 viruses are a group of influenza viruses that normally circulate among birds. The avian influenza A(H7N9) virus is one subgroup among the larger group of H7 viruses. Although some H7 viruses (H7N2, H7N3 and H7N7) have occasionally been found to infect humans, no human infections with H7N9 viruses have been reported until recent reports from China.

News Articles [12 Associated News Articles listed on BioPortfolio]

Medicago awarded a contract by the U.S. Department of Health and Human Services to explore alternate production methods for Ebola antibodies

QUEBEC CITY, Feb. 24, 2015 /PRNewswire/ - Medicago, a leading company in the development and production of plant-based vaccines and therapeutics, announced today that it has received a task order from...

Tracing evolution of chicken flu virus yields insight into origins of deadly H7N9 strain

MEMPHIS, Tenn., Dec. 29, 2014 /PRNewswire-USNewswire/ -- An international research team has shown how changes in a flu virus that has plagued Chinese poultry farms for decades helped create the novel ...

FDA Clears the Focus Diagnostics Simplexa™ Flu A/B & RSV Direct Test to Include Eight Circulating Influenza Viruses

CYPRESS, Calif. and MADISON, N.J., Dec. 9, 2014 /PRNewswire/ -- As the 2014-2015 flu season begins, Focus Diagnostics, the products business of Quest Diagnostics (NYSE: DGX), today announced that...

Medicago Inc. - Product Pipeline Review - 2014

Recently added to the BioPortfolio report store, Medicago Inc. - Product Pipeline Review - 2014 is a new report from Global Markets Direct published on 2014-11-13. This 40-page report is available in...

U.S. FDA Grants Fast Track Designation to Novavax' H7N9 Influenza Virus-Like Particle Vaccine Candidate Adjuvanted With Matrix-M(TM)

GAITHERSBURG, Md., Oct. 29, 2014 (GLOBE NEWSWIRE) -- Novavax, Inc. (Nasdaq:NVAX), a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of recombinant...

Influenza A Infections - Pipeline Review, H2 2014

Recently added to the BioPortfolio report store, Influenza A Infections - Pipeline Review, H2 2014 is a new report from Global Markets Direct published on 2014-09-29. This 141-page report is availabl...

Novavax' H7N9 Avian Influenza VLP Vaccine Candidate With Matrix-M(TM) Delivers Positive Phase 1/2 Clinical Data

Vaccine and adjuvant were well-tolerated, consistent with the company's prior studies with saponin-based adjuvants Hemagglutination-inhibiting antibody responses similar to prior Novavax ...

New York Blood Center's Laboratory of Viral Immunology Gets Support for Developing Vaccines and Therapeutics Against Emerging Viruses

NEW YORK, Sept. 18, 2014 /PRNewswire-USNewswire/ -- NYBC's Laboratory of Viral Immunology has received a National Institutes of Health (NIH) grant to develop a mucosal universal influenza vaccine....

Hemispherx' Drug Ampligen Plus Intranasal Seasonal Influenza Vaccine Induces Cross-Reactive Antibody Formation Against Avian H5N1 and H7N9 Influenza HA in Humans

PHILADELPHIA, Sept. 15, 2014 (GLOBE NEWSWIRE) -- Hemispherx Biopharma, Inc. (NYSE MKT:HEB) (the "Company" or "Hemispherx"), announced today a peer-reviewed publication entitled "Intranasal Seasonal I...

InDevR Wins Barda Contract for Cutting-Edge Influenza Diagnostic

BOULDER, CO--(Marketwired - September 15, 2014) - InDevR, a Boulder-based life science company, announced today that it has signed a contract (HHSO100201400010C) with the Biomedical Advanced Research ...

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Companies [1 Associated Companies listed on BioPortfolio]

Ansun BioPharma

Ansun BioPharma is a clinical stage biopharmaceutical company focused on the development of unique host-directed anti-viral therapies for respiratory viruses. Ansun BioPharma has ...

Clinical Trials [4 Associated Clinical Trials listed on BioPortfolio]

Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Influenza Vaccine(s) GSK3206641A and GSK3206640A Administered in Adults 18 to 64 Years of Age

The purpose of this study is to evaluate the safety and immunogenicity of different formulations of GSK Biologicals' H7N9 influenza vaccine in subjects 18 to 64 years of age.

H7N9 Mix and Match With AS03 and MF59 in Healthy Adults

This Phase II randomized, double-blinded, controlled study in up to 1000 males and non-pregnant females, 19 to 64 years old, inclusive, who are in good health and meet all eligibility crit...

Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Influenza Vaccine(s) GSK3277510A and GSK3277509A in Adults 18 to 60 Years of Age

The purpose of this study is to evaluate the safety and immunogenicity of different formulations of GSK Biologicals' H7N9 influenza vaccine in subjects 18 to 60 years of age.

A Phase I Study Priming With an Inactivated A/H7N9 Influenza Virus Vaccine With or Without MF59 Adjuvant Followed by Live Attenuated A/H7N9 Influenza Virus Vaccine

A phase I prospective, randomized study in healthy adult subjects at a single center. Adult subjects age 18 to 47 years and meeting all enrollment criteria will choose to participate as s...

PubMed Articles [57 Associated PubMed Articles listed on BioPortfolio]

Clinical, Virological and Immunological Features from Patients Infected with Re-Emergent Avian-Origin Human H7N9 Influenza Disease of Varying Severity in Guangdong Province.

The second wave of avian influenza H7N9 virus outbreak in humans spread to the Guangdong province of China by August of 2013 and this virus is now endemic in poultry in this region.

Immunogenicity and Protective Efficacy of a Vero Cell Culture-Derived Whole-Virus H7N9 Vaccine in Mice and Guinea Pigs.

A novel avian H7N9 virus with a high case fatality rate in humans emerged in China in 2013. We evaluated the immunogenicity and protective efficacy of a candidate Vero cell culture-derived whole-virus...

Preexisting human antibodies neutralize recently emerged H7N9 influenza strains.

The emergence and seasonal persistence of pathogenic H7N9 influenza viruses in China have raised concerns about the pandemic potential of this strain, which, if realized, would have a substantial effe...

Memory T Cells Generated by Prior Exposure to Influenza Cross React with the Novel H7N9 Influenza Virus and Confer Protective Heterosubtypic Immunity.

Influenza virus is a source of significant health and economic burden from yearly epidemics and sporadic pandemics. Given the potential for the emerging H7N9 influenza virus to cause severe respirator...

Diverse Heterologous Primary Infections Radically Alter Immunodominance Hierarchies and Clinical Outcomes Following H7N9 Influenza Challenge in Mice.

The recent emergence of a novel H7N9 influenza A virus (IAV) causing severe human infections in China raises concerns about a possible pandemic. The lack of pre-existing neutralizing antibodies in the...

The first lack of evidence of H7N9 avian influenza virus infections among pigs in Eastern China.

In this study, we sought to examine whether evidence existed suggesting that pigs were being infected with the novel H7N9 avian influenza virus. From November 2012 to November 2013, blood was drawn fr...

Outbreaks of Avian Influenza A (H5N2), (H5N8), and (H5N1) Among Birds - United States, December 2014-January 2015.

During December 15, 2014-January 16, 2015, the U.S. Department of Agriculture received 14 reports of birds infected with Asian-origin, highly pathogenic avian influenza A (HPAI) (H5N2), (H5N8), and (H...

Critically Ill Patients With H7N9: New Virus, Old Challenges*

A family cluster of three confirmed cases infected with avian influenza A (H7N9) virus in Zhejiang Province of China.

BackgroundA total of 453 laboratory-confirmed cases of human infected with avian influenza A (H7N9) virus (including 175 deaths) have been reported by WHO till October 2,2014, of which 30.68% (139/453...

Predicting host tropism of influenza A virus proteins using random forest.

Majority of influenza A viruses reside and circulate among animal populations, seldom infecting humans due to host range restriction. Yet when some avian strains do acquire the ability to overcome spe...

Medical and Biotech [MESH] Definitions

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