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Novartis - Biotech, Pharma and Life Science Channel

04:30 EDT 24th May 2013 | BioPortfolio

Novartis is the fourth largest pharmaceutical company in the world, based on annual sales, which are exceeded $36,000m in 2009. Founded in 1996, Novartis focuses of four main areas; pharmaceuticals, vaccines & diagnostics, generic medicines and biosimilars and consumer health (including over--the-counter medications).

The main pharmaceutical focus is on medications for the following areas of disease; Cardiovascular and Metabolism, Oncology (including Hematology), Neuroscience and Ophthalmics, Respiratory and Immunology and Infectious Diseases; and the portfolio contains over 50 key products. 147 products are in the pipeline.

Over 20 vaccines have been developed by Novartis, including influenza, meningitis, polio and tetanus, and the company is also developing diagnostic mechanisms for blood and protection of possible blood infections, which is used by 80% of US blood banks.  Sandoz, a sub-group, has a broad portfolio helping to make affordable, high-quality medicines available to patients around the world and stabilize healthcare systems.

Source; BioPortfolio.com and Novartis.com

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News Articles [ 282 Associated News Articles listed on BioPortfolio]

Key vildagliptin data in The Lancet show for the first time individualized HbA1c treatment goals can be reached in elderly type 2 diabetes patients with no major tolerability issues

Novartis International AG / Key vildagliptin data in The Lancet show for the first time individualized HbA1c treatment goals can be reached in elderly type 2 diabetes patients with no major tolerabi...

New data reinforces strength of Novartis once-daily COPD portfolio in improving lung function, shortness of breath and reducing rate of exacerbations

Novartis International AG / New data reinforces strength of Novartis once-daily COPD portfolio in improving lung function, shortness of breath and reducing rate of exacerbations . Processed and tran...

Thought-Leader Opinion and Clinical Data Indicate that Emerging Agents from Two Drug Classes Have Efficacy Advantages Over Currently Used Therapies for HR-Positive, HER2-Negative Breast Cancer

BURLINGTON, Mass., May 21, 2013 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the effect of an em...

Largest-ever global survey of 1,273 women in 12 countries reveals women with advanced breast cancer feel left out of the breast cancer movement

Novartis International AG / Largest-ever global survey of 1,273 women in 12 countries reveals women with advanced breast cancer feel left out of the breast cancer movement . Processed and transmitte...

Novartis wins GBCHealth Business Action on Health Award for social ventures initiative

Novartis International AG / Novartis wins GBCHealth Business Action on Health Award for social ventures initiative . Processed and transmitted by Thomson Reuters ONE. The issuer is solely responsibl...

Amgen and Novartis Join Atlas Venture Fund IX As Corporate Strategic Partners

Atlas Venture is pleased to announce that it has entered into Corporate Strategic Partnership (CSP) agreements with both Amgen, through its venture capital fund, Amgen Ventures, a...

NextPharma completes executive management team with the appointment of Jean Cuiné as Chief Scientific Officer

NextPharma Technologies Holding Limited, one of the leading contract manufacturers in Europe for the pharmaceutical, biotechnology and healthcare industries, is delighted to annou...

Research Team Publishes New Methods for Synthetic Generation of Influenza Vaccines

LA JOLLA, Calif. and ROCKVILLE, Md., May 15, 2013 /PRNewswire/ -- A team of international researchers from the J. Craig Venter Institute (JCVI), Synthetic Genomics Inc. (SGI), Novartis Vaccines a...

Tokai Pharmaceuticals Announces $35.5 Million Series E Financing

Financing Reflects Encouraging Clinical Progress with Galeterone in Prostate Cancer Tokai Pharmaceuticals, Inc., a biopharmaceutical company focused on developin...

Array BioPharma Announces Clinical Data Presentations At The 2013 ASCO Annual Meeting

BOULDER, Colo., May 15, 2013 /PRNewswire/ -- Array BioPharma Inc. (NASDAQ: ARRY) today announced presentations on its MEK inhibitors, MEK162 (licensed to Novartis) and selumetinib (licensed to AstraZe...

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Clinical Trials [ 65 Associated Clinical Trials listed on BioPortfolio]

Role of Glivec in Patients With Tumor Cells Positive for c-Kit or PDGFR; a Multi Center Study.

This is a phase II, multi-center (Israeli), open label, non-randomized trial for every patient with the specified tumors expressing c-kit or PDGFR. Expression of these kinases will be inv...

Immunogenicity and Safety of an Adjuvanted Inactivated Subunit Influenza Vaccine to Those of a Non-Adjuvanted Inactivated Subunit Influenza Vaccine, When Administered to Adults Affected by Chronic Diseases

This phase III is designed to confirm the previous trial results evaluating the safety, clinical tolerability and immunogenicity of the 2006-2007 formulation of Novartis Vaccines' adjuvant...

Bioequivalence of Vildagliptin Tablet Manufactured in China Compared to Imported Vildagliptin Tablet in Chinese Healthy Volunteers

This study will evaluate the bioequivalence as well as rate and extent of absorption of vildagliptin tablet manufactured by Beijing Novartis Pharma Ltd. compared to the imported vildaglipt...

Rapid Diagnostic Testing and Artemisinin-Based Combination Therapy for Uncomplicated Malaria by Community Health Workers

The purpose of this study is to evaluate the efficiency of a rapid diagnostic test (Paracheck Pf) for the diagnosis of uncomplicated Plasmodium falciparum malaria by community health worke...

Study of STI571 in the Treatment of Patients With Idiopathic Hypereosinophilic Syndrome (HES) and Eosinophilic Leukemias

The purpose of this study is to assess the clinical anti-proliferative activity of STI571 (Glivec®, Novartis, Pharma) in patients with HES defined as: 1. Idiopathic Hypereosinophilic S...

Ketotifen Ophthalmic Solution With Emedastine in Patients With Seasonal Allergic Conjunctivitis

Medications available for the treatment of seasonal allergic conjunctivitis include antihistamines. These medicines block the release of histamine, a substance in the body that is released...

A Continued Access Protocol to Provide Xolair to Patients With Severe Allergic Asthma

This is a continued access protocol to provide subjects who have completed Genentech, Inc. Study Q2143g, Q2195g, or Q2461g or Novartis Pharmaceuticals Corporation Study CIGE025 0010E1 with...

Drug Interaction Between Coartem® and Nevirapine, Efavirenz or Rifampicin in HIV Positive Ugandan Patients

There are increasing numbers of HIV-infected patients in sub-Saharan Africa receiving antiretroviral drugs and/or rifampicin based antituberculous therapy. HIV infected patients are at an...

The High-Dose Aldesleukin (IL-2) "Select" Trial for Patients With Metastatic Renal Cell Carcinoma

High-dose interleukin 2 (Proleukin, Novartis) (IL-2) is approved by the U.S Food and Drug Administration (FDA) for the treatment of metastatic kidney cancer and is a standard treatment of...

Support Annual Strain Update, Safey and Immnogenicity of an Inactivated, Adjuvanted Influenza Vaccine, Formulation 2007-2008, When Administered to Subjects 18-64 Years Affected by Chronic Diseases.

This phase II, open label, is designed as a seasonal study to support annual strain update evaluating the safety, clinical tolerability and immunogenicity of the 2007-2008 formulation of...

PubMed Articles [ 342 Associated PubMed Articles listed on BioPortfolio]

Clinical and economic characteristics of hip fracture patients with and without muscle atrophy/weakness in the United States.

This retrospective analysis of hip fracture patients with and without muscle atrophy/weakness (MAW) revealed that those with MAW had significantly higher healthcare utilization and costs compared with...

A victory for global public health in the Indian Supreme Court.

On 1 April of this year, the Indian Supreme Court upheld the decision of the Indian Patent Office to refuse the patent grant for Novartis imatinib mesylate (Gleevec). The patent application failed to...

Collection, synthesis, and interpretation of evidence: a proof-of-concept study in COPD.

We present a clinical proof-of-concept (PoC) study in chronic obstructive pulmonary disease with the objective of assessing the bronchodilatory effect of an experimental drug as compared with an activ...

Memory and other properties of multiple test procedures generated by entangled graphs.

Methods for addressing multiplicity in clinical trials have attracted much attention during the past 20 years. They include the investigation of new classes of multiple test procedures, such as fixe...

Induction immunosuppression in liver transplantation: a review.

Antibody therapy for induction is seldom used in liver transplantation in the United States, but continues to be used in approximately 10% of patients. The most commonly used antibody at the current t...

V(IV)O Versus V(IV) Complex Formation by Tridentate (O, Narom, O) Ligands: Prediction of Geometry, EPR (51)V Hyperfine Coupling Constants, and UV-Vis Spectra.

Systems formed using the V(IV)O(2+) ion with tridentate ligands containing a (O, Narom, O) donor set were described. Examined ligands were 3,5-bis(2-hydroxyphenyl)-1-phenyl-1H-1,2,4-triazole (H2hyph(P...

Invasive nontyphoidal Salmonella disease in Africa: current status.

Estrogen Receptor α (ERα) and Estrogen Related Receptor α (ERRα) are both transcriptional regulators of the Runx2-I isoform.

Runx2 is a master regulator of bone development and has also been described as an oncogene. Estrogen Receptor α (ERα) and Estrogen Related Receptor α (ERRα), both implicated in bone metabolism and...

Sensitivity of individual-donation and minipool nucleic acid amplification test options in detecting window period and occult hepatitis B virus infections.

BACKGROUND: Several comparison studies showed that the Ultrio assay (Novartis Diagnostics) used in individual-donation nucleic acid amplification testing (ID-NAT) format was as sensitive as the TaqScr...

Hepatitis B virus testing by minipool nucleic acid testing: does it improve blood safety?

BACKGROUND: Hepatitis B virus (HBV) DNA-positive yield since nucleic acid testing (NAT) implementation (minipools of 16 [MP16]) was reported for the first year. We have updated those figures, evalua...

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