Advertisement

Topics

UGenRA - Genitourinary cancer array - Biotech, Pharma and Life Science Channel

09:18 EDT 29th May 2017 | BioPortfolio

UGenRA is a CGI custom-designed oligonucleotide array designed to detect gains and losses of genomic material in endometrial, ovarian, and cervical cancers. Endometrial hyperplasia is a precursor lesion of endometriod endometrial carcinoma (EEC) and since about 50% of women with atypical hyperplasia also have concurrent EEC, it is important to identify those precursor lesions more likely to progress to and those with frank cancer. UGenRATM offers the opportunity to identify such specimens and potentially guide clinical management. Another potential application is to stratify those tumors likely to recur, permitting the identification of patients most likely to benefit from adjuvant therapy. Risk-stratification of stage III/IV ovarian cancer patients after cytoreductive surgery for front-line platinum taxane-based chemotherapy is a potential application for UGenRATM, and the design currently contains the sites of genomic gain/loss with such prognostic value. For any of the three cancers, genomic gain/loss associated with response to particular therapies can be assessed using UGenRATM, especially with the need of only small amounts of starting material and the ability to perform UGenRATM on FFPE specimens.

Source: http://cancergenetics.com/cgi-research/cgh-microarray/  UGenRA is a Registered Trademark of CGI

PubMed Articles [16664 Associated PubMed Articles listed on BioPortfolio]

Clinical utility of a self-administered questionnaire for assessment of hereditary gynecologic cancer.

A patient's medical history and familial cancer history are important information for assessing the risk of hereditary cancer. We have generated a self-administered questionnaire for patients with gyn...

Anal metastasis of rectal cancer-adenocarcinoma of squamous cells: a case report and literature review.

Anal metastasis of colorectal cancer is very rare and is usually associated with a history of anal disease, including anal fistula, fissure, hemorrhoidectomy, and anastomotic injury. We report a case ...

Transcatheter arterial embolization for intercostal arterio-esophageal fistula in esophageal cancer.

While esophageal fistula formation in the adjacent organs is associated with high rates of morbidity and mortality, the management of non-aortic arterio-esophageal fistula has not been frequently repo...

Should the FDA Ban Cigarette Filter Ventilation?

Cigarette Filter Ventilation and its Relationship to Increasing Rates of Lung Adenocarcinoma.

The 2014 Surgeon General's Report on smoking and health concluded that changing cigarette designs have caused an increase in lung adenocarcinomas, implicating cigarette filter ventilation that lowers ...

A fascia lata free flap in pelvic exenteration for Fournier gangrene due to advanced rectal cancer: a case report.

Fournier gangrene due to advanced rectal cancer is a rapidly progressive gangrene of the perineum and buttocks. Emergency surgical debridement of necrotic tissue is crucial, and secondary surgery to r...

Comparison of Tc-99m maraciclatide and Tc-99m sestamibi molecular breast imaging in patients with suspected breast cancer.

Molecular breast imaging (MBI) performed with (99m)Tc sestamibi has been shown to be a valuable technique for the detection of breast cancer. Alternative radiotracers such as (99m)Tc maraciclatide may...

Demonstration of Logic Operations in High-Performance RRAM Crossbar Array Fabricated by Atomic Layer Deposition Technique.

In this paper, resistive random access memory (RRAM)-based crossbar arrays with the cell structure of Pt/[AlO y /HfO x ] m /TiN were fabricated by using atomic layer deposition (ALD) technique. The RR...

Methanethiosulfonate derivatives as ligands of the STAT3-SH2 domain.

With the aim to discover new STAT3 direct inhibitors, potentially useful as anticancer agents, a set of methanethiosulfonate drug hybrids were synthesized. The in vitro tests showed that all the thios...

Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and IGF-1R.

Novel 4-benzylamino benzo-anellated pyrrolo[2,3-b]pyridines have been synthesized with varied substitution patterns both at the molecular scaffold of the benzo-anellated ring and at the 4-benzylamino ...

News Articles [14197 Associated News Articles listed on BioPortfolio]

Harnessing class II histone deacetylases in macrophages to combat breast cancer

A versatile nanoplatform for synergistic combination therapy to treat human esophageal cancer

Pterostilbene suppresses human endometrial cancer cells in vitro by down-regulating miR-663b

Tumor Markers: Supplier Shares by Test, Competitive Strategies, Country Volume and Sales Segment Forecasts, Technology Trends, Instrumentation Review, Emerging OpportunitiesFrance, Germany, Italy, Japan, Spain, UK, US [Updated: 10102016] Prices from USD

Complete report $34,750.nbsp; DataPack test volumes, sales forecasts, supplier shares $21,100.nbsp; The report is available by country, section, market segment, and can be customtailored to your speci...

2016 US Cancer Diagnostics Market: Supplier Shares, Volume and Sales Segment Forecasts, Innovative Technologies, Competitive Strategies [Updated: 09092016] Prices from USD $9800

Complete report $9,800.nbsp; DataPack test volumes, sales forecasts, supplier shares $6,400.VPG Market Research039;s new report is a strategic analysis of the major business opportunities emerging in ...

New Research Points to Need for Standardized Peritoneal Mesothelioma Treatment, According to Surviving Mesothelioma

Scientists in Belgium and the US say there are currently too many different ways to deliver intraperitoneal chemotherapy, making it difficult to collect reliable treatment data. (PRWEB) May 29, 2017 ...

ProstateSpecific Antigen PSA 20172021: US, Europe, JapanOpportunities for Suppliers, Market Segment Forecasts and Shares, Competitive Strategies, Emerging Technologies, Instrumentation Review [Updated: 09122016] Prices from USD $4350

The cancer diagnostics market is on the verge of explosion, as the researchers approach major technological breakthroughs in tumor diagnosis and therapy, discover new specific antigens, and unlock the...

CICATRISATION et TUMORIGENÈSE : Un même processus en commun - Cell

Un mécanisme partagé par le processus de cicatrisation des plaies et le développement des tumeurs est mis en lumière par cette recherche de l'Université de Rockefell...

Estonia Diagnostics Market Forecasts: Blood Banking, Cancer Diagnostics, Clinical Chemistry, Coagulation, Drugs of Abuse, Endocrine Function, Flow Cytometry, Hematology, Immunoproteins, Infectious Diseases, Molecular Diagnostics, TDM [Updated: 15072016] P

This new report from VPG Market Research provides granular analysis of the Estonia diagnostic testing market, including volume and sales forecasts by test for the following market segments:nbsp;nbsp;n...

Drinking more coffee could reduce liver cancer risk, suggests study

Drinking more coffee could reduce the risk of developing the most common form of primary liver cancer, according to a study led by the University of Southampton.

Events [0 Results]

None

Companies [659 Associated Companies listed on BioPortfolio]

NovellusDx

A precision oncology company that developed a novel live cell based assay to characterize the activity of unknown cancer mutations and test their response to targeted therapies. N...

Canines-N-Kids Foundation

WHATCanines-N-Kids Foundation, a nonprofit committed to finding a cure to the devastating cancers that canines and children both develop, is hosting the first Paws f...

Novelogics Biotechnology, Inc. and The Centre for Drug Research and Development (CDRD)

Novelogics Biotechnology Inc. is virtual life sciences company utilizing expertise at a variety of Contract Research labs and is dedicated to developing innovative cancer treatmen...

Cleveland Diagnostics, Inc.

Cleveland Diagnostics, Inc., is a clinical-stage biotechnology company developing technology to improve cancer diagnostics. Its Solvent Interaction Analysis (SIA) technology inves...

Gift of Life Marrow Registry

The Gift of Life Marrow Registry is a national non-profit headquartered in Boca Raton, Fla. The organization, established in 1991, is dedicated to curing blood cancer through marr...

Dendreon

Dendreon Corporation (Nasdaq: DNDN) is a Seattle-based biotechnology company whose mission is to target cancer and transform lives through the discovery, development and commercialization of novel the...

Aravive Biologics, Inc.

Aravive Biologics is a privately held, late pre-clinical stage biopharmaceutical company developing novel, highly selective cancer therapies that treat serious malignancies while ...

Susan G. Komen and Manduka

Susan G. Komen is the world’s largest breast cancer organization, funding more breast cancer research than any other nonprofit outside of the federal government while providi...

Rgenix, Inc.

Rgenix, Inc., is a privately-held clinical-stage biopharmaceutical company focused on the discovery and development of novel cancer drugs that target key pathways in cancer progre...

Proton International

Proton International was founded in 2013 to develop and operate proton centres with high quality clinical partners. Proton International is a subsidiary of Healthcare Technolog...

Clinical Trials [5886 Associated Clinical Trials listed on BioPortfolio]

Phase Ib Study of Chiauranib in Patients With Ovarian Cancer

Chiauranib may stop the growth of tumor cells by blocking Aurora kinase B(Aurora B)、VEGFR/PDGFR/c-Kit、CSF-1R targets. This clinical trial is studying the efficacy and safety of chi...

A Study of Administering FOLFIRINOX Before Surgery For Curable Pancreatic Cancer

Pancreatic cancer is a serious condition and is one of the leading cause of cancer related health problem. It is estimated that in 2016, 5,200 Canadians will be diagnosed with pancreatic c...

Chinese Liver Cancer Clinical Survey

In order to make better use of clinical resources of the real world, strengthen the standardization of PLC diagnosis and treatment, and constantly improve the academic level of liver cance...

Irish Programme for Stratified Prostate Cancer Therapy

The purpose of the trial is to investigate new clinical tests that could predict what treatments work best for certain patients with advanced prostate cancer by identifying markers and ind...

Intermittent Fasting Accompanying Chemotherapy in Gynecological Cancers

The aim of this trial is an evaluation of the effectiveness of intermittent fasting as a supplementary therapy in patients with breast cancer and ovarian cancer in respect to quality of li...

The Safety and Antitumor Activity of the Combination of Oregovomab and Hiltonol in Recurrent Advanced Ovarian Cancer

This is a Phase Ib study to look at the combination of an antibody immunization vaccine strategy using oregovomab and an investigational stage immune booster (poly ICLC / Hiltonol), both o...

Feasibility of Isolating P16 Expression

Expression of the cell cycle regulator p16INK4a increases with age and toxic stressors. In mice, both radiation and chemotherapy are known to increase p16. Due to its influence on age-rela...

Investigation on the Bidirectional Cortical Neuroprosthetic System

The Bidirectional Cortical Neuroprosthetic System (BiCNS) consists of NeuroPort Microelectrode Array Systems and NeuroPort Electrodes (Sputtered Iridium Oxide Film), Patient Pedestals, the...

To Evaluate the Efficacy of NY-ESO-1-specific T Cell Receptor (TCR) Affinity Enhancing Specific T Cell in Solid Tumors

The main purpose of this trial is to investigate the safety and tolerability of TAEST16001(TCR Affinity Enhancing Specific T cell Therapy)in the multi-line treatment failed advanced so...

Homologous Recombination Inquiry Through Ovarian Malignancy Investigations

To investigate the frequency and clinical significance of Homologous Recombination Deficiency (HRD) in Japanese patients with ovarian cancer (including fallopian tube cancer and primary pe...

Videos

None available.

Medical and Biotech [MESH] Definitions

The simultaneous analysis of multiple samples of TISSUES or CELLS from BIOPSY or in vitro culture that have been arranged in an array format on slides or microchips.

A cancer registry mandated under the National Cancer Act of 1971 to operate and maintain a population-based cancer reporting system, reporting periodically estimates of cancer incidence and mortality in the United States. The Surveillance, Epidemiology, and End Results (SEER) Program is a continuing project of the National Cancer Institute of the National Institutes of Health. Among its goals, in addition to assembling and reporting cancer statistics, are the monitoring of annual cancer incident trends and the promoting of studies designed to identify factors amenable to cancer control interventions. (From National Cancer Institute, NIH Publication No. 91-3074, October 1990)

A deoxycytidine derivative and fluorouracil PRODRUG that is used as an ANTINEOPLASTIC ANTIMETABOLITE in the treatment of COLON CANCER; BREAST CANCER and GASTRIC CANCER.

A genus of gram-negative, aerobic, coccoid bacteria whose organisms are part of the normal flora of the oropharynx, nasopharynx, and genitourinary tract. Some species are primary pathogens for humans.

A contiguous gene syndrome associated with hemizygous deletions of chromosome region 11p13. The condition is marked by the combination of WILMS TUMOR; ANIRIDIA; GENITOURINARY ABNORMALITIES; and MENTAL RETARDATION.

Quick Search
Advertisement
 

Relevant Topics

Diagnostics
A diagnostic test is any kind of medical test performed to aid in the diagnosis or detection of disease. For example: to diagnose diseases to measure the progress or recovery from disease to confirm that a person is free from disease Clin...

Women's Health
Women's Health - key topics include breast cancer, pregnancy, menopause, stroke Follow and track Women's Health News on BioPortfolio: Women's Health News RSS Women'...

review and buy UGenRA - Genitourinary cancer array market research data and corporate reports here

Channels Quicklinks