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Adenosine Deaminase - Biotech, Pharma and Life Science Channel

06:38 EDT 26th June 2017 | BioPortfolio

PubMed Articles [488 Associated PubMed Articles listed on BioPortfolio]

Impact of targeting adenosine-induced transient venous reconnection in patients undergoing pulmonary vein isolation for atrial fibrillation: a meta-analysis of 3524 patients.

Atrial fibrillation recurrences after pulmonary vein isolation (PVI) are not uncommon and are frequently related to pulmonary vein reconnection. Adenosine/ATP can reveal dormant pulmonary vein conduct...

A novel fluorescent biosensor for Adenosine Triphosphate detection based on the polydopamine nanospheres integrating with enzymatic recycling amplification.

Based on the protective performance of polydopamine nanospheres (PDANSs) for DNA against nuclease digestion and the specific recognition characteristic of aptamer, we have developed an enzymatic recyc...

Nanocoating cellulose paper based microextraction combined with nanospray mass spectrometry for rapid and facile quantitation of ribonucleosides in human urine.

A rapid and facile analytical method for quantification of ribonucleosides in human urine was developed by the combination of nanocoating cellulose paper based microextraction and nanoelectrospray ion...

Adenosine: an endogenous mediator in the pathogenesis of gynecological cancer.

Extracellular concentration of adenosine increases in the hypoxic tumor microenvironment. Adenosine signaling regulates apoptosis, angiogenesis, metastasis and immune suppression in cancer cells. Aden...

Making the Mark: The Role of Adenosine Modifications in the Life Cycle of RNA Viruses.

Viral epitranscriptomics is a newly emerging field that has identified unique roles for RNA modifications in modulating life cycles of RNA viruses. Despite the observation of a handful of modified vir...

Blockade of GLUT1 by WZB117 resensitizes breast cancer cells to adriamycin.

The tolerance to adriamycin of cancer as a common and stubborn obstacle occurred during curing breast cancer patients needs to be overcome. In the present study, we explored whether inhibiting the glu...

A highly sensitive and widely adaptable plasmonic aptasensor using berberine for small-molecule detection.

Localized surface plasmon resonance (LSPR) biosensors allow label-free detection of small molecules in molecular binding events; however, they are limited by a relatively low sensitivity and narrow dy...

Predator odor evokes sex-independent stress responses in male and female Wistar rats, and reduces phosphorylation of cyclic-adenosine monophosphate response element binding protein (CREB) in the male, but not the female hippocampus.

Post-traumatic stress disorder (PTSD) is characterized by memory disturbances following trauma. Acute predator threat has emerged as an ethological model of PTSD, yet the effects of predator odor on s...

Easy and non-invasive disease detection in pigs by adenosine deaminase activity determinations in saliva.

The quantification of adenosine deaminase (ADA) in porcine saliva samples has been analyzed for its use as a marker of disease. First, an analytical validation of the enzymatic assay used for ADA meas...

Higher Anti-Liver Fibrosis Effect of Cordyceps militaris-Fermented Product Cultured with Deep Ocean Water via Inhibiting Proinflammatory Factors and Fibrosis-Related Factors Expressions.

Deep ocean water (DOW) has been shown to enhance the functional components of fungi, resulting in increased health benefits. Therefore, using DOW for culturing fungi can enhance the cordycepin and ade...

News Articles [83 Associated News Articles listed on BioPortfolio]

Adenosine A2 Receptor Antagonists Pipeline Insights, 2017 [Updated: 30052017] Prices from USD $1063

DelveInsight's, Adenosine A2 Receptor AntagonistsPipeline Insights, 2017, report provides in depth insights on the pipeline drugs and their development activities around the Adenosine A2 Receptor Anta...

Trans-kingdom mimicry underlies ribosome customization by a poxvirus kinase

Ribosomes have the capacity to selectively control translation through changes in their composition that enable recognition of specific RNA elements. However, beyond differential subunit expression du...

Can-Fite BioPharma To Present At The Second Annual Marcum LLP MicroCap Conference

PETACH TIKVA, Israel, May 22, 2013 /PRNewswire/ -- Can-Fite BioPharma (TASE: CFBI, OTC: CANFY), a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory an...

Adenosine Antagonists Pipeline Insights, 2017 [Updated: 30052017] Prices from USD $1063

DelveInsight's, Adenosine AntagonistsPipeline Insights, 2017, report provides in depth insights on the pipeline drugs and their development activities around the Adenosine Antagonists. The DelveInsigh...

Poly Adenosine Diphosphate ADP Ribose Polymerase PARP Inhibitors Pipeline Insights, 2017 [Updated: 30052017] Prices from USD $1063

DelveInsight's, Poly Adenosine Diphosphate ADP Ribose Polymerase PARP InhibitorsPipeline Insights, 2017, report provides in depth insights on the pipeline drugs and their development activities around...

OphthaliX Appoints Dr. Michael Belkin to its Board of Directors

PETACH TIKVA, Israel, July 2, 2013 /PRNewswire/ -- OphthaliX, Inc. (OTC BB: OPLI), is pleased to announce the appointment of Dr. Michael Belkin to the Company's Board of Directors. Dr. Michael Be...

Adenosine A2B Receptor Antagonists Pipeline Insights, 2017 [Updated: 30052017] Prices from USD $1063

DelveInsight's, Adenosine A2B Receptor AntagonistsPipeline Insights, 2017, report provides in depth insights on the pipeline drugs and their development activities around the Adenosine A2B Receptor An...

Adenosine A2A Receptor Antagonists Pipeline Insights, 2017 [Updated: 30052017] Prices from USD $1063

DelveInsight's, Adenosine A2A Receptor AntagonistsPipeline Insights, 2017, report provides in depth insights on the pipeline drugs and their development activities around the Adenosine A2A Receptor An...

Adenosine A3 Receptor Agonists Pipeline Insights, 2017 [Updated: 30052017] Prices from USD $1063

DelveInsight's, Adenosine A3 Receptor AgonistsPipeline Insights, 2017, report provides in depth insights on the pipeline drugs and their development activities around the Adenosine A3 Receptor Agonist...

Adenosine A2A Receptor Agonists Pipeline Insights, 2017 [Updated: 30052017] Prices from USD $1063

DelveInsight's, Adenosine A2A Receptor AgonistsPipeline Insights, 2017, report provides in depth insights on the pipeline drugs and their development activities around the Adenosine A2A Receptor Agoni...

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Companies [2 Associated Companies listed on BioPortfolio]

Inotek Pharmaceuticals Corp.

Inotek Pharmaceuticals is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of therapies for glaucoma and other eye diseases. ...

ArQule, Inc.

ArQule is a biotechnology company engaged in the research and development of next-generation, small-molecule cancer therapeutics. The Company’s targeted, broad-spectrum produ...

Clinical Trials [142 Associated Clinical Trials listed on BioPortfolio]

Myocardial Perfusion and Fibrosis in Cancer Survivors

This is a cross-sectional pilot study. The investigators seek to obtain early information pertaining to the relationship between measurements of myocardial perfusion reserve and myocardial...

Gene Study for Infantile Onset Diabetes

Diabetes mellitus is a group of metabolic diseases characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both. According to American Diabe...

Role of Microglia in the Pathogenesis of Progressive Multiple Sclerosis

Our aim is to evaluate whether translocator binding protein (TSPO)-imaging correlates to Expanded Disability Status Scale (EDSS) and other disease progression-related clinical and paraclin...

Varlitinib in Combination With mFOLFOX6 for Advanced or Metastatic Gastric Cancer (First Line)

This protocol for Varlitinib is developed for the treatment of Gastric Cancer. Varlitinib (also known as ASLAN001) is a small-molecule, adenosine triphosphate competitive inhibitor of the ...

Determination of Coronarphysiological Parameters With the Method of Thermodillution

The gold standard to induce coronary hyperemia for measurement of fractional flow reserve (FFR), coronary flow reserve (CFR) and index of microcirculatory resistance (IMR) is adenosine, bu...

Post-Static Cold Storage Hypothermic Oxygenated Perfusion in Bergamo Liver Transplant Program

In light of the widespread organ shortage, dynamic preservation by means of Machine Perfusion (MP) has been proposed as a strategy to increase the pool of suitable grafts for liver transpl...

Varlitinib in Combination With Capecitabine for Advanced or Metastatic Biliary Tract Cancer

This protocol for Varlitinib is developed for the treatment of Biliary Tract Cancer. Varlitinib (also known as ASLAN001) is a small-molecule, adenosine triphosphate competitive inhibitor o...

The Effect of A2A Adrenoceptor Stimulation on the Diameter of Retinal Arterioles During Hypoxia in Vivo

The purpose is to investigate how the adenosine affects the diameter regulation of retinal arterioles during changes in oxygen tension. A deeper understanding of the mechanisms involved in...

A Phase 1 Open Label Study to Evaluate Adenosine 2A Receptor Agonist (Regadenoson) in Patients Undergoing Lung Transplantation

This study will evaluate the maximum safe dose and duration of regadenoson (Lexiscan) that can be given to people who are having a lung transplant. Regadenoson will be given as a continuou...

Fractional Flow Reserve Fax Registry

The Fractional Flow Reserve Fax Registry is an investigator-initiated, real-world registry to analyze the use of fractional flow reserve (FFR) measurements in clinical practice in cardiac ...

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Medical and Biotech [MESH] Definitions

Drugs that inhibit ADENOSINE DEAMINASE activity.

An enzyme that catalyzes the hydrolysis of adenosine to inosine with the elimination of ammonia. Since there are wide tissue and species variations in the enzyme, it has been used as a tool in the study of human and animal genetics and in medical diagnosis. EC 3.5.4.4.

A nucleoside that is composed of adenine and d-ribose. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.

A ribonucleoside antibiotic synergist and adenosine deaminase inhibitor isolated from Nocardia interforma and Streptomyces kaniharaensis. It is proposed as an antineoplastic synergist and immunosuppressant.

A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.

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