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Adrenergic modifiers - Biotech, Pharma and Life Science Channel

22:55 EDT 26th March 2017 | BioPortfolio

PubMed Articles [317 Associated PubMed Articles listed on BioPortfolio]

Associations among left ventricular systolic function, tachycardia, and cardiac preload in septic patients.

In sepsis, tachycardia may indicate low preload, adrenergic stimulation, or both. Adrenergic overstimulation is associated with septic cardiomyopathy. We sought to determine whether tachycardia was as...

Potassium-Channel-Independent Relaxing Influence of Adipose Tissue on Mouse Carotid Artery.

Since the cardiovascular consequences of obesity reportedly vary in different types of obesity, we investigated the influence of adipose tissue from different locales on the phenylephrine-induced tone...

In silico search for modifier genes associated with pancreatic and liver disease in Cystic Fibrosis.

Cystic Fibrosis is the most common lethal autosomal recessive disorder in the white population, affecting among other organs, the lung, the pancreas and the liver. Whereas Cystic Fibrosis is a monogen...

Genomics of Acute Myeloid Leukemia Diagnosis and Pathways.

In recent years, our understanding of the molecular pathogenesis of myeloid neoplasms, including acute myeloid leukemia (AML), has been greatly advanced by genomics discovery studies that use novel hi...

Iatrogenic thyrotoxicosis and the role of therapeutic plasma exchange.

Thyroid storm or severe thyrotoxicosis results from extreme thyroid hormone elevation. Therapy includes medical management to prevent hormone production, release, recycling, and peripheral conversion ...

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

Identification of effective combination therapies is critical to address the emergence of drug-resistant cancers, but direct screening of all possible drug combinations is infeasible. Here we introduc...

Nickel and cadmium-induced SLBP depletion: A potential pathway to metal mediated cellular transformation.

Both nickel and cadmium compounds have been established as group I carcinogens for several decades. Despite over-whelming evidence of these compounds' carcinogenicity in humans, the specific underlyin...

Deconstructing the germinal center, one cell at a time.

Successful vaccination relies on driving the immune response towards high specificity, affinity and longevity. Germinal centers facilitate the evolution of antigen-specific B cells by iterative rounds...

Race and sex differences in cardiovascular α-adrenergic and β-adrenergic receptor responsiveness in men and women with high blood pressure.

Hypertension is associated with unfavorable changes in adrenergic receptor responsiveness, but the relationship of race and sex to adrenergic receptor responsiveness in the development of cardiovascul...

Cocaine and coronary artery diseases: a systematic review of the literature.

Cocaine is associated with important cardiac complications such as sudden death, acute myocarditis, dilated cardiomyopathy, life-threatening arrhythmias, and myocardial ischemia as well as infarction....

News Articles [52 Associated News Articles listed on BioPortfolio]

Visceral Pain Pipeline Review, H1 2017 [Updated: 15032017] Prices from USD $2000

Visceral Pain Pipeline Review, H1 2017SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Visceral Pain Pipeline Review, H1 2017, provides an overview of the V...

DuPont Performance Materials Announces High-Performance Materials for 3D Printing

Products Showcase at Additive Manufacturing Users Group Conference WILMINGTON, Del. (PRWEB) March 20, 2017 DuPont Performance Materials announces participation in the 3D printing industry at the Addi...

Pharmathen Pharmaceuticals SA Pharmaceuticals Healthcare Deals and Alliances Profile [Updated: 21022017] Prices from USD $250

SummaryPharmathen Pharmaceuticals SA Pharmathen is a pharmaceutical company that develops and markets generic products. The company's products include retinoid, serotonin and noradrenaline reuptake in...

GlobalMed Announces Acquisition of TreatMD

GlobalMed®, the worldwide leader in telemedicine delivery solutions with over 3.5 million consults in 2016, announced today the acquisition of TreatMD out of Miami, Florida. Term...

Global Hypertrophic Cardiomyopathy Therapeutics Market by Drug Classes, Clinical Pipeline and Forecast to 2020, New Findings by iHealthcareAnalyst, Inc.

Maryland Heights, MO, March 08, 2017 --(PR.com)-- The global hypertrophic cardiomyopathy therapeutics market growing at a rate of 1.8% CAGR, is estimated to reach USD 1.2 Billion by 2020 due to highe...

Global Hospital Pharmaceutical Drugs Market by Indications, Therapeutic Applications, Growth Trends and Forecast to 2020, New Report by iHealthcareAnalyst, Inc.

Maryland Heights, MO, March 04, 2017 --(PR.com)-- The global hospital pharmaceutical drugs market is estimated to reach USD 235 Billion in 2020, expanding at a CAGR of 2.8% from 2016 to 2020, due to ...

Arbutus Biopharma Corp ABUS Pharmaceuticals Healthcare Deals and Alliances Profile [Updated: 17022017] Prices from USD $250

SummaryArbutus Biopharma Corp Arbutus Biopharma formerly Tekmira Pharmaceuticals Corporation, is a biopharmaceutical company which focuses on the development and commercialization of proprietary drugs...

Acadia Pharmaceuticals Inc ACAD Pharmaceuticals Healthcare Deals and Alliances Profile [Updated: 17022017] Prices from USD $250

SummaryAcadia Pharmaceuticals Inc Acadia is a biopharmaceutical company, which focuses on the discovery, development and commercialization of small molecule drugs for the treatment of central nervous ...

ANI Pharmaceuticals Acquires Inderal® XL and InnoPran XL®

BAUDETTE, Minn., Feb. 24, 2017 /PRNewswire/ -- ANI Pharmaceuticals, Inc. ("ANI") (Nasdaq: ANIP) today announced that it has acquired Inderal® XL from Cranford Pharmaceuticals, LLC and InnoPran X...

Positive Results for Relvar® Ellipta® Lung Function Study in Patients with Well-Controlled Asthma

GlaxoSmithKline plc (LSE/NYSE: GSK) and Innoviva, Inc. (NASDAQ: INVA) today announced positive headline results from a non-inferiority lung function study, which demonstrated t...

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Companies [3 Associated Companies listed on BioPortfolio]

Partikula LLC

Partikula is a preclinical stage biotechnology company focused on developing novel therapies for cancer and other diseases based on platform chemistry technologies, including its ...

Innate Immunotherapeutics Limited

Innate Immunotherapeutics Limited is a public unlisted biopharmaceutical company based in Auckland, New Zealand. The company is focused on the development of a new generation of i...

Innate Therapeutics Limited

Innate Therapeutics Limited is a public unlisted biopharmaceutical company based in Auckland. The company is focused on the development of a new generation of immune response modi...

Clinical Trials [141 Associated Clinical Trials listed on BioPortfolio]

Adrenergic System in Islet Transplantation

To determine the effect of sympathetic neural and hormonal (epinephrine) input on islet cell hormonal responses to insulin-induced hypoglycemia in type 1 diabetic recipients of intrahepati...

Dexmedetomidine Versus Magnesium Sulphate for Caesarean Delivery

Regional anesthesia has become more popular in cesarean deliveries because most of the parturients prefer being awake during the birth process. In addition, regional anesthesia may be a sa...

Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta 3-Adrenergic Receptor Agonists

Background: Brown adipose tissue (BAT) is a type of fat in the body. It may prevent weight gain, improve insulin sensitivity, and reduce fatty liver. Researchers want to see if BAT helps ...

Ephedrine and Phenylephrine for Spinal Hypotension

Spinal anesthesia is widely used as the procedure of choice for cesarean delivery. In comparison to epidural anesthesia it is faster, easier to perform, patients are more comfortable, comp...

Trelegy ELLIPTA ® Inhaler: Qualitative Analysis and Subject Preference Survey

Three main classes of inhaled treatment exist for chronic obstructive pulmonary disease (COPD): Beta2-adrenergic agonists (which may be short (SABA) or long (LABA) acting), long-acting mus...

Cutaneous Autonomic Pilomotor Testing to Unveil the Role of Neuropathy Progression in Early Parkinson's Disease

In Parkinson's disease (PD), alpha-synuclein accumulation in cutaneous autonomic pilomotor and sudomotor nerve fibers has been linked to autonomic nervous system disturbances even in the e...

The Influence of Electronic and Traditional Cigarettes Smoking on Hemodynamic Parameters

It is intended to examine 50 healthy volunteers aged 18 - 60 years. 12-hour abstinence from tobacco smoke, alcohol or coffee before the experiment will be required. The exclusion criteria ...

Dexmedetomidine on Basal Ganglia Neuronal Activity in Parkinson's Disease

The implantation of a deep brain stimulator (DBS) is an established option to improve the symptoms of Parkinson's disease (PD) in patients that do not respond adequately to medical therapy...

Pulse Reduction On Beta-blocker and Ivabradine Therapy

Heart failure with reduced left ventricular ejection fraction (HFrEF) is the most common form of chronic heart failure in subjects ≤ 75 years of age. Beta-blocker therapy greatly reduces...

Effect of Topical Phenylephrine 2.5% on EVP in Normal Human Eyes

Phenylephrine hydrochloride ophthalmic solution is an alpha-1 adrenergic receptor agonist commonly used topically for dilation prior to ocular fundus examination. In the eye, phenylephrine...

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Medical and Biotech [MESH] Definitions

Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters.

Drugs that bind to but do not activate ADRENERGIC RECEPTORS. Adrenergic antagonists block the actions of the endogenous adrenergic transmitters EPINEPHRINE and NOREPINEPHRINE.

A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). beta-3 Adrenergic receptors are the predominant beta-adrenergic receptor type expressed in white and brown ADIPOCYTES and are involved in modulating ENERGY METABOLISM and THERMOGENESIS.

Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.

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