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Adrenergic modifiers - Biotech, Pharma and Life Science Channel

04:51 EDT 27th July 2017 | BioPortfolio

PubMed Articles [345 Associated PubMed Articles listed on BioPortfolio]

Associations among left ventricular systolic function, tachycardia, and cardiac preload in septic patients.

In sepsis, tachycardia may indicate low preload, adrenergic stimulation, or both. Adrenergic overstimulation is associated with septic cardiomyopathy. We sought to determine whether tachycardia was as...

Dopamine acting at D1-like, D2-like and α1-adrenergic receptors differentially modulates theta and gamma oscillatory activity in primary motor cortex.

The loss of dopamine (DA) in Parkinson's is accompanied by the emergence of exaggerated theta and beta frequency neuronal oscillatory activity in the primary motor cortex (M1) and basal ganglia. DA re...

TLR4 and C5aR crosstalk in dendritic cells induces a core regulatory network of RSK2, PI3Kβ, SGK1, and FOXO transcription factors.

Crosstalk between complement component 5a receptors (C5aRs) and TLRs in dendritic cells (DCs) occurs upon pathogen invasion; however, studies on C5aR and TLR crosstalk mainly focused on the modulating...

Atorvastatin reduces β-Adrenergic dysfunction in rats with diabetic cardiomyopathy.

In the diabetic heart the β-adrenergic response is altered partly by down-regulation of the β1-adrenoceptor, reducing its positive inotropic effect and up-regulation of the β3-adrenoceptor, increas...

The role of β-adrenergic receptors and p38MAPK signaling pathways in physiological processes of cardiosphere-derived cells.

The effects of β adrenergic receptors (β-ARs) and p38 mitogen-activated protein kinases (MAPK) pathways on cardiosphere-derived cells (CDCs) are largely unknown. This study aimed to investigate the ...

Chemical generation of volatile species of copper - Optimization, efficiency and investigation of volatile species nature.

This work is a comprehensive study on chemical generation of volatile species (VSG) of copper for analytical atomic spectrometry. VSG was carried out in a flow injection mode in a special arrangement ...

Loneliness is adversely associated with physical and mental health and lifestyle factors: Results from a Swiss national survey.

Loneliness is a common, emotionally distressing experience and is associated with adverse physical and mental health and an unhealthy lifestyle. Nevertheless, little is known about the prevalence of l...

Reciprocal Modulation of Helper Th1 and Th17 Cells by the β2-Adrenergic Receptor Agonist Drug Terbutaline.

Catecholamine hormones are powerful regulators of the immune system produced by the sympathetic nervous system. They regulate the adaptive immune system by altering T cell differentiation into T helpe...

Reliable HPLC separation, vibrational circular dichroism spectra, and absolute configurations of isoborneol enantiomers.

Resolution of chiral compounds has played an important role in the pharmaceutical field, involving detailed studies of pharmacokinetics, physiological, toxicological, and metabolic activities of enant...

Bottom-up assembly of salivary gland microtissues for assessing myoepithelial cell function.

Myoepithelial cells are flat, stellate cells present in exocrine tissues including the salivary glands. While myoepithelial cells have been studied extensively in mammary and lacrimal gland tissues, l...

News Articles [48 Associated News Articles listed on BioPortfolio]

Gastrointestinal Drugs Market Global Report 2017 Including: Antacids, Antiulcerants, Vitamin And Minerals, Antiobesity Drugs, Antiemetics And Antinauseants, AntidiarrhoealsCovering: AbbVie, Johnson Johnson, Takeda Pharmaceticals, Allergan, and UCB [Repo

Gastrointestinal drug market covers the medicines used for the treatment of colon cancer, colitis, diverticular disease, perianal infections, anal fissures, hemorrhoids, constipation, and irritable bo...

Coding Updates Virtual Boot Camp 2018: Live Webinar by AudioEducator

This live webinar will prepare medical coders and professionals for success in 2018 by analyzing the most recent changes to ICD-10 and CPT codes for 10 specialties. Durham, NC (PRWEB) July 25, 2017 A...

Anthrax Fusion Toxins with Improved Ability to Penetrate Cells

Available for licensing are novel conjugated or fusion proteins comprised of anthrax toxin lethal factor cytolethal distending toxin subunit B. Several human tumor cell lines have been found to be hig...

Researchers pinpoint why some don't respond to beta-blockers

New research may show why some

Novel mechanism underlying efficacy of common heart failure drug identified

Beta-blocker drugs serve a key role in the treatment of heart failure, preventing bombardment of the heart by catecholamines -- substances like epinephrine and norepinephrine -- which overexcite and s...

Researchers identify novel mechanism underlying efficacy of common heart failure drug

Beta-blocker drugs serve a key role in the treatment of heart failure, preventing bombardment of the heart by catecholamines - substances like epinephrine and norepinephrine - which overexcite and str...

Temple researchers identify novel mechanism underlying efficacy of common heart failure drug

(Temple University Health System) Beta-blocker drugs serve a key role in the treatment of heart failure, preventing bombardment of the heart by catecholamines -- substances like epinephrine and norepi...

Visceral Pain Market Size to Reach USD 14.22 Billion by 2024: Hexa Research

FELTON, California, June 27, 2017 /PRNewswire/ -- The global visceral pain market is expected to reach USD 14.22 billion by 2024, driven by the increasing geriatric population globally. Increasing...

SENOMYX TO WEBCAST CORPORATE PRESENTATION AT THE 15TH ANNUAL NEEDHAM GROWTH CONFERENCE

SAN DIEGO, CA, January 8, 2013 /PRNewswire/ -- Senomyx, Inc. (NASDAQ: SNMX), a  company using proprietary taste science technologies to discover and develop novel flavor ingredients for the ...

Parent Project Muscular Dystrophy Grants $175,000 for Biomarkers, Non-Ambulatory Endpoints in Duchenne Muscular Dystrophy

Dr. Craig McDonald of UC Davis to Receive Supplemental Funds HACKENSACK, N.J., Jan. 18, 2013 /PRNewswire-USNewswire/ -- Parent Project Muscular Dystrophy (PPMD) has awarded Dr. Craig McDona...

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Companies [4 Associated Companies listed on BioPortfolio]

Addivant

Addivant™ is an innovator in the field of polymer additives, developing customized solutions that provide customers enhanced application performance, safe handling, and reduc...

Partikula LLC

Partikula is a preclinical stage biotechnology company focused on developing novel therapies for cancer and other diseases based on platform chemistry technologies, including its ...

Innate Immunotherapeutics Limited

Innate Immunotherapeutics Limited is a public unlisted biopharmaceutical company based in Auckland, New Zealand. The company is focused on the development of a new generation of i...

Innate Therapeutics Limited

Innate Therapeutics Limited is a public unlisted biopharmaceutical company based in Auckland. The company is focused on the development of a new generation of immune response modi...

Clinical Trials [147 Associated Clinical Trials listed on BioPortfolio]

Esmolol to Control Adrenergic Storm in Septic Shock- ROLL-IN 2

Septic shock is a common syndrome caused by the body's response to an infection. Septic shock is responsible for 10% of all ICU admissions and 30% of ICU deaths. Use of "beta blocker" medi...

Comparison Between Epinephrine and Clonidine as Adjuvants to Lidocaine in Axillary Brachial Plexus Block.

Adjuncts to local anaesthetics for the peripheral nerve blocks such as epinephrine, clonidine and opioids have been widely used to enhance quality, duration of anaesthesia and postoperativ...

Prevelance of Fragmented QRS Complex and Prolonged QT Interval in Cirrhotic Patients

.Cardiac affection in liver cirrhosis is a clinical condition characterized by impaired diastolic relaxation and contractility with electrophysiological abnormalities. .Cirrhotic patients...

Comparative Low and High Dose of Dexmedethomidine in Pituitary Tumor Removal by Transphenoid Approach

Transnasal transsphenoidal (TNTS) resection of pituitary tumors involves wide fluctuation in hemodynamic parameter and causes hypertension and tachycardia due to intense noxious stimuli du...

B2 Adrenergic Receptor Gene Polymorphism in Bronchial Asthma

The b2-adrenoceptor (b2AR) mediates the physiological responses in the airway, which include bronchodilation, bronchoprotection. The b2-adrenoceptor (b2AR) mediates the physiological respo...

Efficacy of Ketamine Infusion Compared With Traditional Anti-epileptic Agents in Refractory Status Epilepticus

The study will investigate the efficacy of the NMDA receptor antagonist ketamine as a first line agent in refractory status epilepticus versus traditional general anesthetic agents used fo...

Adrenergic System in Islet Transplantation

To determine the effect of sympathetic neural and hormonal (epinephrine) input on islet cell hormonal responses to insulin-induced hypoglycemia in type 1 diabetic recipients of intrahepati...

Dexmedetomidine Versus Magnesium Sulphate for Caesarean Delivery

Regional anesthesia has become more popular in cesarean deliveries because most of the parturients prefer being awake during the birth process. In addition, regional anesthesia may be a sa...

Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta 3-Adrenergic Receptor Agonists

Background: Brown adipose tissue (BAT) is a type of fat in the body. It may prevent weight gain, improve insulin sensitivity, and reduce fatty liver. Researchers want to see if BAT helps ...

Ephedrine and Phenylephrine for Spinal Hypotension

Spinal anesthesia is widely used as the procedure of choice for cesarean delivery. In comparison to epidural anesthesia it is faster, easier to perform, patients are more comfortable, comp...

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Medical and Biotech [MESH] Definitions

Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters.

Drugs that bind to but do not activate ADRENERGIC RECEPTORS. Adrenergic antagonists block the actions of the endogenous adrenergic transmitters EPINEPHRINE and NOREPINEPHRINE.

A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). beta-3 Adrenergic receptors are the predominant beta-adrenergic receptor type expressed in white and brown ADIPOCYTES and are involved in modulating ENERGY METABOLISM and THERMOGENESIS.

Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.

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