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Adrenergic modifiers - Biotech, Pharma and Life Science Channel

11:07 EST 20th January 2017 | BioPortfolio

PubMed Articles [300 Associated PubMed Articles listed on BioPortfolio]

Cerebrovascular Diseases in Childhood Cancer Survivors: Role of the Radiation Dose to Willis Circle Arteries.

The aim of this study was to investigate the role of radiation dose received to the circle of Willis (WC) during radiation therapy (RT) and of potential dose-response modifiers on the risk of stroke a...

Epigenetics in Normal and Malignant Hematopoiesis: An Overview and Update 2017.

Epigenetic regulation in hematopoiesis has been a field of rapid expansion. Genome-wide analyses have revealed, and will continue to identify genetic alterations in epigenetic genes that are present i...

Adrenergic Gate Release for Spike Timing-Dependent Synaptic Potentiation.

Spike timing-dependent synaptic plasticity (STDP) serves as a key cellular correlate of associative learning, which is facilitated by elevated attentional and emotional states involving activation of ...

Alpha-thalassaemia promotes frequent vaso-occlusive crises in children with sickle cell anaemia through haemorheological changes.

Sickle cell anaemia (SCA) is a severe hereditary haemoglobinopathy characterised by haemorheological abnormalities, which play a role in the occurrence of several acute and chronic clinical complicati...

Browning of white adipose tissue: lessons from experimental models.

Beige or brite (brown-in-white) adipocytes are present in white adipose tissue (WAT) and have a white fat-like phenotype that when stimulated acquires a brown fat-like phenotype, leading to increased ...

Detection and pharmacokinetics of salmeterol in thoroughbred horses following inhaled administration.

Salmeterol is a man-made beta-2-adrenergic receptor agonist used to relieve bronchospasm associated with inflammatory airway disease in horses. Whilst judicious use is appropriate in horses in trainin...

Pharmacokinetics and selected pharmacodynamics of romifidine following low-dose intravenous administration in combination with exercise to quarter horses.

Romifidine is an alpha-2 adrenergic agonist used for sedation and analgesia in horses. As it is a prohibited substance, its purported use at low doses in performance horses necessitates further study....

Beta2-adrenergic signaling affects the phenotype of human cardiac progenitor cells through EMT modulation.

Human cardiac progenitor cells (CPCs) offer great promises to cardiac cell therapy for heart failure. Many in vivo studies have shown their therapeutic benefits, paving the way for clinical translatio...

Direct Synthesis of Highly Designable Hybrid Metal Hydroxide Nanosheets Using Tripodal Ligands as One-Size-Fits-All Modifiers.

Brucite-type layered metal hydroxides are prepared from diverse metallic elements and have outstanding functions; however, their poor intercalation ability significantly limits their chemical designab...

Lactobacillus rhamnosus GR-1 Attenuates Induction of Hypertrophy in Cardiomyocytes but Not through Secreted Protein MSP-1 (p75).

Previous animal studies have shown that the administration of probiotic Lactobacillus rhamnosus can provide a protective effect against ischemia/reperfusion and necrotic injury to the intestine, liver...

News Articles [44 Associated News Articles listed on BioPortfolio]

Antimicrobial Plastic Market by Type Commodity Plastic, Engineering Plastic, and High Performance Plastic by Application Healthcare, Packaging, Consumer Goods, Automotive, Construction, and Others by Region Global Forecast to 2020 Prices from USD $5650

Antimicrobial plastic are polymers which are mainly used to reduce or restrain the growth of microorganisms such as algae, bacteria, and fungi on any plastic products to maintain hygiene and increase ...

Automotive Brake Friction Product Market by OE Aftermarket Brake Pads, Shoes, Lining, Rotor, and Drum Material type PadsNon Metallic, SemiMetallic, Ceramic, LiningOrganic, SemiMetallic Synthetic Industry Trends Forecast to 2019 Prices from USD $5650

The automotive brake friction products market has witnessed considerable growth in countries such as China, India, and Brazil, owing to upcoming emission norms. Given the increased vehicle production ...

Pharmathen Pharmaceuticals SA Pharmaceuticals Healthcare Deals and Alliances Profile Prices from USD $250

SummaryPharmathen Pharmaceuticals SA Pharmathen is a pharmaceutical company that develops and markets generic products. The company's products include retinoid, serotonin and noradrenaline reuptake in...

Arbutus Biopharma Corp ABUS Pharmaceuticals Healthcare Deals and Alliances Profile Prices from USD $250

SummaryArbutus Biopharma Corp Arbutus Biopharma formerly Tekmira Pharmaceuticals Corporation, is a biopharmaceutical company which focuses on the development and commercialization of proprietary drugs...

Rheology Modifiers Market by Type Organic and Inorganic, Application Paints Coatings, Cosmetics Personal Care, Adhesives Sealants, Inks, Pharmaceuticals, HII Products, Oil Gas, and Construction Global Trends Forecasts to 2020 Prices from USD $5650

Rheology modifiers are used in various applications to control the rheological profiles through modification of viscosity. Their major applications include paints coatings, cosmetics personal care, ...

Personal Care Ingredients Market by Type Surfactants, Conditioning Polymers, Emollients, Rheology Modifiers and Others and by Application Skin Care, Hair Care, Oral Care and Others Global Trends Forecasts to 2020 Prices from USD $5650

The personal care ingredients market is projected to register a CAGR of 5.4% between 2015 and 2020 to reach $17,600.0 million. The market for personal care ingredients is estimated to grow on account ...

Kaneka North America, LLC To Increase The Off List Selling Price For Kane Ace® Specialty Additives

PASADENA, Texas, Jan. 3, 2017 /PRNewswire/ -- Due to continuing increases in key raw materials, Kaneka North America, LLC will increase the off list selling price for Kane Ace® MBS specialty additive...

Non-amyloidogenic effects of α2 adrenergic agonists: implications for brimonidine-mediated neuroprotection

A Landmark EHR Usability Study Measuring Productivity Improvement for EHR Data Capture with a Dictation Method

“Natural Language Processing–Enabled and Conventional Data Capture Methods for Input to Electronic Health Records: A Comparative Usability Study” has been published in JMIR Medical Informatics. ...

American Process, Inc. Announces Hydrophobic Nanocellulose Patent Granted by USPTO

American Process, Inc. announces that the U.S. Patent and Trademark Office has granted U.S. Patent No. 9,499,637 on November 22, 2016 for “NANOCELLULOSE COMPOSITIONS AND PROCESSES TO PRODUCE SAME....

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Companies [3 Associated Companies listed on BioPortfolio]

Partikula LLC

Partikula is a preclinical stage biotechnology company focused on developing novel therapies for cancer and other diseases based on platform chemistry technologies, including its ...

Innate Immunotherapeutics Limited

Innate Immunotherapeutics Limited is a public unlisted biopharmaceutical company based in Auckland, New Zealand. The company is focused on the development of a new generation of i...

Innate Therapeutics Limited

Innate Therapeutics Limited is a public unlisted biopharmaceutical company based in Auckland. The company is focused on the development of a new generation of immune response modi...

Clinical Trials [134 Associated Clinical Trials listed on BioPortfolio]

Dexmedetomidine on Basal Ganglia Neuronal Activity in Parkinson's Disease

The implantation of a deep brain stimulator (DBS) is an established option to improve the symptoms of Parkinson's disease (PD) in patients that do not respond adequately to medical therapy...

Pulse Reduction On Beta-blocker and Ivabradine Therapy

Heart failure with reduced left ventricular ejection fraction (HFrEF) is the most common form of chronic heart failure in subjects ≤ 75 years of age. Beta-blocker therapy greatly reduces...

Effect of Topical Phenylephrine 2.5% on EVP in Normal Human Eyes

Phenylephrine hydrochloride ophthalmic solution is an alpha-1 adrenergic receptor agonist commonly used topically for dilation prior to ocular fundus examination. In the eye, phenylephrine...

Preoperative Administration of Tamsulosin for Prevention of Post Operative Urinary Retention in Males Undergoing Elective Inguinal Hernia Repair

Double blinded, randomized controlled prospective study looking at 2 preoperative doses of Tamsulosin an alpha-adrenergic blocker in preventing post-operative urinary retention. A previous...

Beta Blockade in in Traumatic Brain Injury

The purpose of this study is test the effect of beta-adrenergic blockade on mortality in patients with traumatic brain injury with the hypothesis being that the addition of beta blockade t...

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Efficacy of BC 007 in Healthy Subjects

Berlin Cures develops BC 007 to treat patients suffering from diseases (chronic heart failure, pulmonary hypertension, chronic fatigue syndrome etc.) which are associated with functional a...

Beta Adrenergic Receptor Blockade as a Novel Therapy for Patients With Adenocarcinoma of the Prostate

This will be a single arm, window of opportunity study in men with treatment-naïve prostate cancer who will proceed to prostatectomy. Men will be treated with carvedilol prior to undergoi...

Beta2-mimetic and Central Nervous System

Beta2-mimetics such as Salbutamol have been shown to have ergogenic effects. Acute and chronic inhaled or oral doses of Salbutamol have been shown to increase whole body exercise and muscl...

Mirabegron For Erectile Dysfunction

The only class of oral erectile dysfunction (ED) medication on the market are the phosphodiesterase Type 5 inhibitors (PDE5i). This pilot study is being done to evaluate the effect of Mira...

Study of a Propranolol (HEMANGIOL®) and Oral Metronomic Vinorelbine (NAVELBINE®) Combination for Children and Teenagers With Refractory/Relapsing Solid Tumors

Cancer remains the first cause of death due to disease in children and adolescents despite important progress and 70% of the survivors present sequelae. It is therefore mandatory to genera...

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Medical and Biotech [MESH] Definitions

Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters.

Drugs that bind to but do not activate ADRENERGIC RECEPTORS. Adrenergic antagonists block the actions of the endogenous adrenergic transmitters EPINEPHRINE and NOREPINEPHRINE.

A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). beta-3 Adrenergic receptors are the predominant beta-adrenergic receptor type expressed in white and brown ADIPOCYTES and are involved in modulating ENERGY METABOLISM and THERMOGENESIS.

Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.

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