Adrenergic modifiers - Biotech, Pharma and Life Science Channel

18:51 EDT 25th October 2014 | BioPortfolio

PubMed Articles [367 Associated PubMed Articles listed on BioPortfolio]

Direct detection of free fatty acids in edible oils using supercritical fluid chromatography coupled with mass spectrometry.

Determination of free fatty acids (FFAs) in food products is of enormous interest mainly because they are related to the quality and authenticity of the oils. In this study, supercritical fluid chroma...

Begin Preparing for 2015 Coding Changes: Use 4 New Modifiers Instead of Modifier 59.

Increased adrenergic signaling is responsible for decreased glucose-stimulated insulin secretion in the chronically hyperinsulinemic ovine fetus.

Insulin may stimulate its own insulin secretion and is a potent growth factor for the pancreatic β-cell. Complications of pregnancy such as diabetes and intrauterine growth restriction are associated...

Meta-Regression Analyses to Explain Statistical Heterogeneity in a Systematic Review of Strategies for Guideline Implementation in Primary Health Care.

This study is an in-depth-analysis to explain statistical heterogeneity in a systematic review of implementation strategies to improve guideline adherence of primary care physicians in the treatment o...

Sex Differences in β-Adrenergic Responsiveness of Action Potentials and Intracellular Calcium Handling in Isolated Rabbit Hearts.

Cardioprotection in females, as observed in the setting of heart failure, has been attributed to sex differences in intracellular calcium handling and its modulation by β-adrenergic signaling. Howeve...

Optogenetic Stimulation of Adrenergic C1 Neurons Causes Sleep State Dependent Cardiorespiratory Stimulation and Arousal with Sighs in Rats.

ABSTRACT Rationale: The rostral ventrolateral medulla (RVLM) contains central respiratory chemoreceptors (retrotrapezoid nucleus, RTN) and the sympathoexcitatory, hypoxia-responsive C1 neurons. Simult...

Exploring the Local Elastic Properties of Bilayer Membranes using Molecular Dynamics Simulations.

Membrane mechanical elastic properties regulate a variety of cellular processes involving local membrane deformation, such as ion channel function and vesicle fusion. In this work, we use molecular dy...

Altered synaptic architecture and glycosylated synaptomatrix composition in a Drosophila classic galactosemia disease model.

Classic galactosemia (CG) is an autosomal recessive disorder resulting from loss of galactose-1-phosphate uridyltransferase (GALT) that catalyzes conversion of galactose-1-phosphate and uridine diphos...

Driver and Passenger Mutations in Cancer.

Next-generation sequencing has allowed identification of millions of somatic mutations and epigenetic changes in cancer cells. A key challenge in interpreting cancer genomes and epigenomes is distingu...

Enhanced pan-PPAR gene and protein expression in adipose tissue of diet-induced obese mice treated with Telmisartan.

Telmisartan has previously been used to target obesity, showing PPARβ/δ related effects in white adipose tissue (WAT). We sought to evaluate whether Telmisartan enhances gene and protein expression ...

News Articles [72 Associated News Articles listed on BioPortfolio]

Sunovion Pharmaceuticals Inc. to Present Data for COPD Portfolio and Pipeline at CHEST 2014

Data Presented by Sunovion Further Demonstrates Commitment to Providing Treatment Options for Patients with COPD Sunovion Pharmaceuticals Inc. (Sunovion) announced today that ...

The Nuts and Bolts of Global Surgical Package Requirements

Expert speaker Dr. Duane Abbey is reviewing the Global Surgical Package Concept in healthcare payment system on Tue, Oct 21 on behalf of AudioEducator.com. Durham, NC (PRWEB) October 20, 2014 In a ma...

Neothetics, PolyPid file for IPOs

Neothetics Inc. (San Diego, Calif.) and PolyPid Ltd. (Petach Tikva, Israel) filed for IPOs on NASDAQ. Neothetics filed to raise up to $63.3 million with Piper Jaffray; Guggenheim Securities; and Need...

Anoro's COPD Drug Shows Improved Lung Function

Respiratory Medicine has published positive results from a third lung function study comparing the efficacy and safety of Anoro Ellipta (umeclidinium /vilanterol, ‘UMEC/VI’), the combination long-...

Xolair (Asthma) - Forecast and Market Analysis to 2023

Recently added to the BioPortfolio report store, Xolair (Asthma) - Forecast and Market Analysis to 2023 is a new report from GlobalData published on 2014-08-30. This 52-page report is available in PD...

Singulair (Asthma) - Forecast and Market Analysis to 2023

Recently added to the BioPortfolio report store, Singulair (Asthma) - Forecast and Market Analysis to 2023 is a new report from GlobalData published on 2014-08-30. This 54-page report is available in...

Fostair (Asthma) - Forecast and Market Analysis to 2023

Recently added to the BioPortfolio report store, Fostair (Asthma) - Forecast and Market Analysis to 2023 is a new report from GlobalData published on 2014-08-30. This 53-page report is available in P...

Spiriva (Asthma) - Forecast and Market Analysis to 2023

Recently added to the BioPortfolio report store, Spiriva (Asthma) - Forecast and Market Analysis to 2023 is a new report from GlobalData published on 2014-08-30. This 55-page report is available in P...

Advair (Asthma) - Forecast and Market Analysis to 2023

Recently added to the BioPortfolio report store, Advair (Asthma) - Forecast and Market Analysis to 2023 is a new report from GlobalData published on 2014-08-30. This 53-page report is available in PD...

Symbicort (Asthma) - Forecast and Market Analysis to 2023

Recently added to the BioPortfolio report store, Symbicort (Asthma) - Forecast and Market Analysis to 2023 is a new report from GlobalData published on 2014-08-30. This 52-page report is available in...

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Companies [2 Associated Companies listed on BioPortfolio]

Innate Immunotherapeutics Limited

Innate Immunotherapeutics Limited is a public unlisted biopharmaceutical company based in Auckland, New Zealand. The company is focused on the development of a new generation of i...

Innate Therapeutics Limited

Innate Therapeutics Limited is a public unlisted biopharmaceutical company based in Auckland. The company is focused on the development of a new generation of immune response modi...

Clinical Trials [79 Associated Clinical Trials listed on BioPortfolio]

Terlipressin + Albumin Versus Midodrine + Octreotide in the Treatment of Hepatorenal Syndrome

From 1999, several studies have showed that the use of vasoconstrictors in association with albumin are effective in the treatment of hepatorenal syndrome (HRS). The rationale of the use o...

Stress During Deep Sedation With Propofol With and Without Alfentanil

This is a randomized clinical trial of deep procedural sedation with propofol with and without supplemental alfentanil. Patients will be assessed for total and fractionated serum catechol...

Study to Evaluate Esmolol (Brevibloc) to Manage Cardiac Function in Patients With Subarachnoid Hemorrhage

The purpose of this study is to evaluate the clinical effect of esmolol treatment on cardiac function and electrophysiology; to assess the effects of esmolol treatment on serum adrenergic ...

Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM)

To compare two standard treatment strategies for atrial fibrillation: ventricular rate control and anticoagulation vs. rhythm control and anticoagulation.

Study of Alpha-2 Adrenergic Receptor Dysfunction in Regional Lipoatrophy

OBJECTIVES: I. Determine the response in plasma norepinephrine concentration and plasma glycerol to the agonist (clonidine) and the antagonist (yohimbine) of the alpha-2 adrenergic recept...

Occluded Artery Trial (OAT)

The purpose of this study is to determine whether opening an occluded infarcted artery 3-28 days after an acute myocardial infarction in high-risk asymptomatic patients reduces the composi...

Active Immunotherapy Of Metastatic Renal Cell Carcinoma Using Autologous Dendritic Cells Transfected With Autologous Total Tumor RNA

The feasibility and dose-limiting toxicity of administering escalating doses of dendritic cells transfected with autologous renal cell carcinoma RNA DC(DCRCC-RNA) will be defined. As a sec...

Brain Receptors in Sympathetic Nervous System Regulation

The purpose of this study is to investigate the role of brain receptors called alpha2-adrenoreceptors in regulating the sympathetic nervous system, which maintains the supply of blood and ...

Gene Modifiers of Cystic Fibrosis Lung Disease

Ths purpose of this study is to examine genetic modifiers of the severity of cystic fibrosis lung disease.

Genetics and Cardiovascular Reactivity in Young Twins

To evaluate the effects of genetic variants in all of the nine adrenergic receptor subtype genes, alone or in combination, on cardiovascular reactivity and other quantitative cardiovascula...

Medical and Biotech [MESH] Definitions

Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters.

Drugs that bind to but do not activate ADRENERGIC RECEPTORS. Adrenergic antagonists block the actions of the endogenous adrenergic transmitters EPINEPHRINE and NOREPINEPHRINE.

A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). beta-3 Adrenergic receptors are the predominant beta-adrenergic receptor type expressed in white and brown ADIPOCYTES and are involved in modulating ENERGY METABOLISM and THERMOGENESIS.

Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.

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