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AgeRelated Macular Degeneration AMD or ARMD - Biotech, Pharma and Life Science Channel

15:16 EDT 21st May 2013 | BioPortfolio

PubMed Articles [ 3680 Associated PubMed Articles listed on BioPortfolio]

Phenotypic characterization of a Chinese family with autosomal dominant cone-rod dystrophy related to GUCY2D.

BACKGROUND: This study aimed to evaluate the clinical phenotype and investigate the molecular genetic defect in a Chinese family with autosomal dominant cone-rod dystrophy (ADCRD). METHODS: Family his...

Clinical effects of stereotactic radiation surgery in patients with metastatic melanoma.

We examined the effectiveness of stereotactic radiation surgery (SRS) in 14 patients with brain metastasis in our hospital. The age of the patients ranged 45-85 years old (mean, 65). Brain metastasis...

BOON (Bonn ophthalmology online network) : Concept of an integrative databank for monitoring patients under intravitreal therapy.

BACKGROUND: Previous studies have proven that long-lasting success in the therapy of neovascular age-related macular degeneration (AMD) and other neovascular retinal diseases depends on monthly follow...

A Quantitative Analysis of the Spontaneous Reporting of Congestive Heart Failure-Related Adverse Events With Systemic Anti-Fungal Drugs.

To investigate spontaneous reporting relationships between representative antifungal agents and congestive heart failure (CHF)-related adverse events (AE) we performed multiple disproportionality anal...

An optogenetic tool for the activation of endogenous diaphanous-related formins induces thickening of stress fibers without an increase in contractility.

We have developed an optogenetic technique for the activation of diaphanous-related formins. Our approach is based on fusion of the light-oxygen-voltage 2 domain of Avena sativa Phototrophin1 to an is...

Characteristics of fundus autofluorescence and drusen in the fellow eyes of Japanese patients with exudative age-related macular degeneration.

BACKGROUND: The main purpose of this study is to investigate the characteristics of fundus autofluorescence (FAF) and area of soft drusen among the fellow eyes of unilateral typical age-related macula...

Age-related Differences in Tongue-Palate Pressures for Strength and Swallowing Tasks.

The tongue plays a key role in the generation of pressures for transporting liquids and foods through the mouth in swallowing. Recent studies suggest that there is an age-related decline in tongue str...

Event-related desynchronization and synchronization quantification in motor-related EEG by Kolmogorov entropy.

Objective. Various approaches have been applied for the quantification of event-related desynchronization/synchronization (ERD/ERS) in EEG/MEG data analysis, but most of them are based on band power a...

Expression and Relationship of Proinflammatory Chemokine RANTES/CCL5 and Cytokine IL-1β in Painful Human Intervertebral Discs.

STUDY DESIGN.: Laboratory study. OBJECTIVE.: To evaluate expression of chemokine regulated and normal T cell expressed and secreted (RANTES)/C-C motif ligand 5 (CCL5) and interleukins in intervertebra...

Evaluation of intervertebral disc cartilaginous endplate structure using magnetic resonance imaging.

PURPOSE: The cartilaginous endplate (CEP) is a thin layer of hyaline cartilage positioned between the vertebral endplate and nucleus pulposus (NP) that functions both as a mechanical barrier and as a...

News Articles [ 2703 Associated News Articles listed on BioPortfolio]

Early-life traffic-related air pollution exposure linked to hyperactivity

Early-life exposure to traffic-related air pollution was significantly associated with higher hyperactivity scores at age 7, according to new research from the University of Cincinnati (UC) and Cincin...

14 closely related crocodiles existed around 5 million years ago

(University of Zurich) 14 species of crocodile lived in South America around 5 million years ago, at least seven of which populated the coastal areas of the Urumaco River in Venezuela at the same time...

TRACON Pharmaceuticals Announces TRC105 Clinical Trials, Abstract Presentations at 2013 ASCO Annual Meeting

SAN DIEGO, May 20, 2013 /PRNewswire/ -- TRACON Pharmaceuticals, a biopharmaceutical company that develops targeted therapies for oncology and ophthalmology, today announced multiple clinical inve...

PSivida Corporation And GTx: 2 Of The Most Undervalued Biotechs For 2013

By Bob's Stocks: pSivida (PSDV) is a leading provider of miniaturized, sustained-release drug delivery products, and is continuing the evolution of these systems. The company has developed three of on...

Research uncovers a potential role of two proteins in diabetes

(Medical Xpress)—Flinders University researchers are breaking new ground in a decade-long journey to pinpoint the function of two closely related proteins.

A functional variant in the CFI gene confers a high risk of age-related macular degeneration

Johannes van de Ven and colleagues report a rare missense mutation in CFI encoding a p.Gly119Arg substitution that confers a high risk of AMD. Sera from AMD cases carrying the p.Gly119Arg variant medi...

Singapore Stocks - Factors to watch on May 20

Following are some company-related and market news which could have an impact on the local market. --------------------MARKET SNAPSHOT @ 0002 GMT--------- INSTRUMENT LAST PCT CHG NET CHG S&P 500 1667....

Heat-Related Fatalities Are Projected To Rise Steeply In Manhattan Due To Warming Climate

Residents of Manhattan will not just sweat harder from rising temperatures in the future, says a new study; many may die. Researchers say deaths linked to warming climate may rise some 20 percent by t...

Heat-related deaths in Manhattan projected to rise: Killing season may push into spring and fall

Researchers say deaths in Manhattan linked to warming climate may rise some 20 percent by the 2020s, and, in some worst-case scenarios, 90 percent or more by the 2080s. Higher winter temperatures may...

Boston Brother and Sister Battle Odds to Overcome Autism with Help from Center for Autism and Related Disorders

Boston, MA (PRWEB) May 20, 2013 Seven-year-old Torin Phillips and his 6-year-old sister, Kaia, are on a mission to overcome the limiting effects of autism. The two siblings, who live just outside o...

Events [ 1 Associated Events listed on BioPortfolio]

14th INTERNATIONAL CONFERENCE ON ALZHEIMER'S DRUG DISCOVERY

The annual Alzheimer's Drug Discovery Foundation (ADDF) conference brings together academic and industry scientists intent on accelerating the development of innovative treatments for Alzheimer’s di...

Companies [ 163 Associated Companies listed on BioPortfolio]

Health & Parenting

Health & Parenting Ltd provides a range of family-related applications for iPod, iPhone and Android. These include a pregnancy, fertility and period app. Health & Parenting Ltd of...

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

Johnson & Johnson

Johnson & Johnson is the world's most comprehensive and broadly-based manufacturer of health care products, as well as a provider of related services, for the consumer, pharmaceutical and me...

Easton-Bell Sports

Easton-Bell Sports, Inc. is a leading designer, developer and marketer of branded sports equipment, protective products and related accessories. The company markets and licenses p...

IPC The Hospitalist Company, Inc.

IPC The Hospitalist Company, Inc. (Nasdaq: IPCM) is a leading physician group practice company focused on the delivery of hospitalist medicine and related facility-based services. IPC's physicians and...

U.S. Physical Therapy, Inc.

Founded in 1990, U.S. Physical Therapy, Inc. (NASDAQ:USPH) operates 369 clinics in 43 states. The Company's clinics provide preventative and post-operative care for a variety of o...

First Databank (FDB)

FDB provides drug knowledge that helps healthcare professionals make precise medication-related decisions. With thousands of customers worldwide, FDB enables our information syste...

Acucela Inc.

Acucela Inc. is a clinical-stage biotechnology company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye di...

Cellmid Limited

Cellmid is an Australian biotechnology company developing innovative novel therapies and diagnostic tests for inflammatory diseases, heart attack and cancer. Cellmid holds the lar...

AmerisourceBergen Corporation

AmerisourceBergen is one of the world's largest pharmaceutical services companies serving the United States, Canada and selected global markets. Servicing both healthcare provider...

Clinical Trials [ 1228 Associated Clinical Trials listed on BioPortfolio]

Safety and Efficacy Study of Dexamethasone Versus Ranibizumab in Patients With Diabetic Macular Edema

This study will compare the safety and efficacy of the 700 ug dexamethasone intravitreal implant with ranibizumab 0.5 mg intravitreal injections in patients with diabetic macular edema (DM...

Intravitreal LFG316 in Patients With Age-related Macular Degeneration (AMD)

This study is designed to test the efficacy of twelve successive monthly doses of intravitreal (IVT) LFG316 on the growth of geographic atrophy (GA) lesions. The study will also provide in...

Proton Pump Inhibitor Therapy for Mild to Moderate Obstructive Sleep Apnea

Obstructive Sleep Apnea (OSA) is common in modern society, affecting up to 5% of working middle-aged adults in the United States. Obesity is the number one risk factor for the development...

Trial of the Impact of Vitamin A on Maternal Mortality

Main objectives: To evaluate the impact of weekly vitamin A supplementation (VAS) to women of reproductive age (15-45 years) on maternal mortality in rural Ghana, and to compare this with...

Study of the Use of Coated Venous Catheters in the Critically Ill Child

This study should help determine to determine whether or not the use of an antibiotic coated catheter will significantly reduce the number of central line related bloodstream infections in...

Alleviated Positioning for Small Macular Holes

Rational of the study: There are arguments to think that the closure of macular holes can be obtained without a strict positioning under certain conditions, i.e. hole size ≤ 400 µm, if...

Efficacy of Sirolimus-Based, Steroid Avoidance Immunosuppression African Americans

African Americans receiving a kidney transplant are considered at high risk for early rejection of their transplanted kidney and require more immunosuppression to maintain their kidney tra...

Stem Cell Transplantation With Identical Donors for Patients With Sickle Cell Disease

This protocol studied the effect of administration of a myeloablative pretransplant preparative regimen followed by an infusion of donor stem cells in children with severe sickle cell dise...

Reducing Risk and Trauma-Related Stress in Persons Living With HIV

This two-year study tested the concept that an intervention, which reduces trauma-related symptoms among adults who are living with human immunodeficiency virus (HIV), are experiencing tra...

Effectiveness of Prolonged Exposure Therapy on Reducing Neuroendocrine-Related Symptoms of Post-Traumatic Stress Disorder in Women

This study will determine the effectiveness of immediate treatment with prolonged exposure therapy (PE) versus delaying treatment with PE in altering neuroendocrine-related symptoms of pos...

Medical and Biotech [MESH] Definitions

Cycadophyta

A division of GYMNOSPERMS which look like palm trees (ARECACEAE) but are more closely related to PINUS. They have large cones and large pinnate leaves and are sometimes called cycads, a term which may also refer more narrowly to cycadales or CYCAS.

Dna Shuffling

The use of DNA recombination (RECOMBINATION, GENETIC) to prepare a large gene library of novel, chimeric genes from a population of randomly fragmented DNA from related gene sequences.

Patient Access To Records

The freedom of patients to review their own medical, genetic, or other health-related records.

Adaptor Protein Complex 1

A clathrin adaptor protein complex primarily involved in clathrin-related transport at the TRANS-GOLGI NETWORK.

Adaptor Protein Complex 2

An adaptor protein complex primarily involved in the formation of clathrin-related endocytotic vesicles (ENDOSOMES) at the CELL MEMBRANE.

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