"epothilone Ovarian Neoplasms" Channels 
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Showing "epothilone Ovarian Neoplasms" Channels, all 16
Ovarian cancer is cancer that starts in the female reproductive organs, the ovaries. It is the fifth most common cancer among women. Women at risk of Ovarian cancer are those who have had few children (or had children at an older age), carriers o...
Ovarian Follicular Development
MatBA - Mature B-cell neoplasm array
Mature B-cell neoplasms arise in B-cells that have entered germinal centers within lymph nodes as part of the immune response. They display great heterogeneity at the clinical, pathologic, and genetic levels and represent 6-7% and 5-6% of all new estimat...
Epithelial cell adhesion molecule EpCAM CD326
Epithelial cell adhesion molecule (EpCAM; CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types, including prostate, breast, colon, gastric, ovarian, pancreatic and lung cancer. Overexpression of EpCAM has...
UGenRA - Genitourinary cancer array
UGenRA is a CGI custom-designed oligonucleotide array designed to detect gains and losses of genomic material in endometrial, ovarian, and cervical cancers. Endometrial hyperplasia is a precursor lesion of endometriod endometrial carcinoma (EEC) and sinc...
Luteinizing hormone (LH), a gonadotropin, stimulates the gonads - in males, the testes, and in females, the ovaries. It is essential for reproduction, and secreted from cells in the anterior pituitary called gonadotrophs. In females, ovulation of mature...
Tumor markers are substances produced by tumor cells or by other cells of the body in response to cancer or certain benign (noncancerous) conditions. These substances can be found in the blood, in the urine, in the tumor tissue, or in other tissues. Diff...
Fluorescent in situ hybridization (FISH) is a sensitive and accurate technique that allows the detection of chromosome aberrations. In this method, a single-stranded fluorescent-labeled nucleic acid sequence (probe) complementary to a target genomic sequ...
The European Organization for Rare Diseases considers orphan diseases to be those that are rare (occur in 1 in 1500 to 1 in 2500 patients, according to US Rare Disease Act 2002 and European Commission on Public Health) and neglected (due the low financia...
The BRCA MASTR Dx is a molecular diagnostic assay for the identification of mutations in the coding regions of the BRCA 1&2 genes in individuals with increased risk for breast, ovarian and/or related cancers compatible with Roche’s 454 sequence...
The Ras-Raf-MEK-ERK (ERK) pathway is a logical therapeutic target because it represents a common downstream pathway for several key growth factor tyrosine kinase receptors which are often mutated or overexpressed in human cancers. Although considered mai...
UroGenRA - Genitourinary cancer array
UroGenRA is a CGI custom-designed oligonucleotide array for implementation within a clinical laboratory as an array CGH-based diagnostic/prognostic tool for kidney, prostate, and bladder cancers. It was designed to detect gains and losses that frequently...
Progression through the cell cycle is monitored by surveillance mechanisms known as cell cycle checkpoints. Dysfunction in cell cycle checkpoints leads to genomic instability and contributes to tumor progression. Checkpoint kinase 1 (CHK-1) plays a criti...
p53 - protein 53 - tumor protein 53
The p53 molecule is centrally important to the apoptosis pathway, and found in many cell pathways leading to apoptosis. As a tumour suppressor protein, its downstream compounds act to prevent apoptosis and cell death. This is significant in that is makes...
