"approves Neupro formulation indications" Channels 
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Showing "approves Neupro formulation indications" Channels, all 23
Revascularization Modalities and Indications
Hepatitis B Immune Globulin Cangene
HepaGam B® [Hepatitis B Immune Globulin (Human) Injection] contains purified antibodies specific for the hepatitis B surface antigen (HBsAg). * It is approved in Canada and the United States for two indications making it the only product of its kin...
Drug Delivery - news, views, blogs
Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. Drug delivery technologies are patent protected formulation technologies that modify drug release profile, absor...
Histone Deacetylase HDAC Inhibitors
Histone deacetylase (HDAC) inhibitors are emerging as a new class of potential anticancer agents for the treatment of solid and hematological malignancies. HDAC inhibition causes acetylated nuclear histones to accumulate in both tumor and normal tissues,...
Tumor Necrosis Factor TNF Products
Tumor Necrosis Factor (TNF) and TNF receptor antagonists and agonists used to treat TNF-mediated inflammatory diseases such as rheumatoid arthritis or to treat cancer. TNF blockers are the commercially most successful single-target group of biologic th...
Technical Background Tumor necrosis factor (TNF) is a substance made by your body's immune system. People with inflammatory diseases such as rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, juvenile idiopathic arthritis, and ankylosing...
OxyContin, an narcotic analgesic produced by Purdue Pharma LP, nets $3m in sales annually, placing it 8th in the world for annual sales. OxyContin in the brand name for oxycodone, and is similar to morphine. Indications include control of moderate to s...
Generics Drugs - news, views, reports
A generic drug (generic drugs, short: generics) is a drug defined as "a drug product that is comparable to brand/reference listed drug product in dosage form, strength, route of administration, quality and performance characteristics, and intended u...
Phosphodiesterase 4 PDE 4 Inhibitors
Phosphodiesterase 4 (PDE-4) inhibitors have attracted considerable interest as potential therapeutic agents for diseases including chronic obstructive pulmonary disease. PDE-4 inhibitors are known to reduce elevated cAMP concentrations in inflammatory cell...
The classical tissue factors typically are proteins used for tissue repair and growth stimulation. Among the approved products are the growth factors PDGF, IGF, EGF, BMP and FGF. One of the commercially most successful growth factors is BMP-2 from Medtroni...
p38 mitogen activated protein kinase MAPK Inhibitors
The next generation of p38 mitogen-activated protein kinase (MAPK) inhibitors has reached clinical proof-of-concept studies in phase II in a broad range of indications. While the previous generation of p38 MAPK inhibitors suffered from side effects such as...
Epithelial cell adhesion molecule EpCAM CD326
Epithelial cell adhesion molecule (EpCAM; CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types, including prostate, breast, colon, gastric, ovarian, pancreatic and lung cancer. Overexpression of EpCAM has...
Cytokine Tumour Necrosis Factor (TNF)
TNF is a compound that is classified as a cytokine which plays a central role in the cellular mechanisms of apoptosis or cell death. However, there are a number of different kinds of TNF, just under twenty, but the family of molecules have very similar a...
Bone morphogenetic protein rhBMP
Bone morphogenetic protein 2 (rhBMP-2) is approved by the Food and Drug Administration for anterior lumbar interbody fusion and for acute open tibial fractures; rhBMP-7, on the other hand, is approved for long bone defects and has received a humanitarian d...
Rivaroxaban is the most broadly indicated novel oral anticoagulant and is marketed under the brand name Xarelto®. To date, Xarelto has been approved for use in the following indications across the venous arterial thromboembolic (VAT) space: The...
Although the human cytokines interleukin-2 (IL-2) and tumor necrosis factor (TNF) alpha are approved marketed for tumor therapy, their use is rather limited due to severe systemic side effects. Targeted delivery of the cytokine may be an approach to redu...
Varicella zoster virus (VZV) is one of eight herpes viruses known to infect humans (and other vertebrates). Varicella-zoster virus is known by many names, including: chickenpox virus, varicella virus, zoster virus, and human herpes virus type 3 (HHV-3)....
Vancomycin is an antobiotic indicated for the treatment of serious, life-threatening infections by Gram-positive bacteria that are unresponsive to other less-toxic antibiotics. In particular, vancomycin should not be used to treat methicillin-sensitive S...
The chimeric anti-CD20 antibody rituximab (Rituxan & MabThera) from Biogen Idec and Genentech/Roche is one of the world’s commercially most successful antibodies (2007 sales of over US$ 5 bln). Rituximab was first approved in 1997 by the FDA for...
Despite the humorous name, hedgehog signalling cascades are central to embryonic development and has been implicated in the development of a number of diseases, including cancer. The downstream cascades of the Hedgehog pathway have considerable overlap...
Fibroblast Growth Factors FGFs
The family of fibroblast growth factors (FGFs) regulates a plethora of developmental processes, including brain patterning, branching morphogenesis and limb development. Quite a number of FGF-R agonists are in development or even marketed in a range of...
Technical background: HUMIRA is a tumor necrosis factor (TNF) blocker - further details can be viewed: Tumor Necrosis Factor TNF Cytokine Tumour Necrosis Factor (TNF) Mechanism of Action: Adalimumab is a recombinant human anti-TNF mono...
ImuXen® is a liposomal technology platform designed to improve the delivery and effectiveness of DNA, protein and polysaccharide vaccines. Proof of concept preclinical studies with a number of vaccines have shown that ImuXen® technology can hel...