Allergies - Biotech, Pharma and Life Science Channel
The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms and disease in a predisposed person, which in turn can cause inconvenience, or a great deal of misery. An allergy is everything from a runny nose, itchy eyes and palate to skin rash.
Allergy is widespread and affects approximately one in four of the population in the UK at some time in their lives. Each year the numbers are increasing by 5% with as many as half of all those affected being children.
Allergic reactions are caused by substances in the environment known as allergens. Almost anything can be an allergen for someone. Allergens contain an organic molecule, protein.
The most common allergens are pollen from trees and grasses, house dust mite, moulds, pets such as cats and dogs, insects like wasps and bees, industrial and household chemicals, medicines, and foods such as milk and eggs. Less common allergens include nuts, fruit and latex. There are some non-protein allergens which include drugs such as penicillin. For these to cause an allergic response they need to be bound to a protein once they are in the body.
An allergic person's immune system believes allergens to be damaging and so produces a special type of antibody (IgE) to attack the invading material. This leads other blood cells to release further chemicals (including histamine) which together cause the symptoms of an allergic reaction.
Source; Allergy UK
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PubMed Articles
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Clinical Trials
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Videos
The Allergy
Behind the scenes: http://www.youtube.com/watch?v=svqzA6lo3ww Bloopers at: http://wongfuproductions.com/2010/08/new-short-the-allergy-outtakes/ Sometimes all...
Medical and Biotech [MESH] Definitions
National Institute Of Allergy And Infectious Diseases (u.s.)
Component of the NATIONAL INSTITUTES OF HEALTH. It conducts and supports basic and applied research to better understand, treat, and ultimately prevent infectious, immunologic, and allergic diseases. It was established in 1948.
Multi-ingredient Cold, Flu, And Allergy Medications
A broad category of multi-ingredient preparations that are marketed for the relief of upper respiratory symptoms resulting from the COMMON COLD; ALLERGIES; or HUMAN INFLUENZA. While the majority of these medications are available as OVER-THE-COUNTER DRUGS some of them contain ingredients that require them to be sold as PRESCRIPTION DRUGS or as BEHIND-THE COUNTER DRUGS.
Urticaria
A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.
Nasal Decongestants
Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993)
Terfenadine
A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
