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Anabolic Steroids - Biotech, Pharma and Life Science Channel

23:52 EDT 19th May 2013 | BioPortfolio

PubMed Articles [ 1256 Associated PubMed Articles listed on BioPortfolio]

Effective treatment of a steroid-induced femoral neck fracture nonunion with a once-weekly administration of teriparatide in a rheumatoid patient: a case report.

INTRODUCTION: Nonunion of femoral neck fractures frequently occurs in elderly patients. In patients with rheumatoid arthritis, reoperation rates after internal fixation of a displaced femoral neck fra...

Determination of 136 pharmaceuticals and hormones in sewage sludge using quick, easy, cheap, effective, rugged and safe extraction followed by analysis with liquid chromatography-time-of-flight-mass spectrometry.

The aim of this study was to develop an analytical method for the analysis of a wide range of hormonal steroids and pharmaceutical compounds in sewage sludge. Thus, 136 substances were selected, inclu...

Stereotactic laser induced thermotherapy (LITT): a novel treatment for brain lesions regrowing after radiosurgery.

Since the inception of radiosurgery, the management of brain metastases has become a common problem for neurosurgeons. Although the use of stereotactic radiosurgery and/or whole brain radiation therap...

Nonheme Iron-Mediated Amination of C(sp(3))-H Bonds. Quinquepyridine-Supported Iron-Imide/Nitrene Intermediates by Experimental Studies and DFT Calculations.

The 7-coordinate complex [Fe(qpy)(MeCN)2](ClO4)2 (1, qpy = 2,2':6',2″:6″,2''':6''',2''''-quinquepyridine) is a highly active nonheme iron catalyst for intra- and intermolecular amination of C(sp(3...

Profiling intact steroid sulfates and unconjugated steroids in biological fluids by liquid chromatography-tandem mass spectrometry (LC-MS-MS).

Within the combined DFG research project "Sulfated Steroids in Reproduction" an analytical method was needed for determining sulfated and unconjugated steroids with highest specificity out of differen...

Incidence of anabolic steroid counterfeiting in Brazil.

This retrospective study reports data obtained from the National Institute of Criminalistics of the Brazilian Federal Police Department (DPF) on 3676 anabolic products seized between 2006 and 2011. An...

Evaluation of the association between Hispanic ethnicity and disease activity and severity in a large cohort of patients with juvenile idiopathic arthritis.

To examine the association between ethnicity and disease activity in patients with juvenile idiopathic arthritis (JIA), and to determine the association of ethnicity with disease severity and disabili...

Regression of conjunctival maltoma with topical antibiotics and steroids.

Effects of steroid administration and transcorneal electrical stimulation on the anatomic and electrophysiologic deterioration of nonarteritic ischemic optic neuropathy in a rodent model.

PURPOSE: To elucidate the effectiveness of steroid administration and transcorneal electrical stimulation (TES) on anatomic changes and visual function in a rodent model of nonarteritic ischemic optic...

Magnetic resonance imaging (MRI) in paediatric psychoneuroendocrinology: a new frontier for understanding the impact of hormones on emotion and cognition.

Mounting magnetic resonance imaging (MRI) research is characterising the neurobiological trajectories of healthy human brain development. In parallel, studies increasingly acknowledge the relevance of...

News Articles [ 295 Associated News Articles listed on BioPortfolio]

Qigong Exercises | How “Qigong Secrets” Helps People Create Balance In Their Autonomic Nervous System – V kool

Qigong Secrets developed by Marcus Santer is a new course that provides people with Qigong exercises, and Qigong techniques helping people create balance in their autonomic nervous system. A full Qigo...

Combination Drug Therapy May Be Best Treatment For Osteoporosis

The combination of two different drugs for osteoporosis was found to increase bone mineral density (BMD) more than treatment with either drug alone, according to the results of a small clinical trial...

Bayer/Algeta win 1st mCRPC alpha-emitting pharmaceutical OK

With the speed at which Dr Richard Pazdur's office at the FDA is approving cancer drugs in recent months, one would think the Office of Hematology and Oncology Products was on steroids, or at least,...

Adonis Golden Ratio Review Released by TotalWellnessCleanse.net

Chicago, IL (PRWEB) May 15, 2013 Adonis Golden Ratio has finally been released after much anticipation and is helping men everywhere finally gain the lean, muscular physique they’ve always wan...

[Comment] Is it time to combine osteoporosis therapies?

Some therapies licensed to treat osteoporosis work by inhibiting bone turnover (anticatabolic agents) and some by stimulating bone formation (anabolic agents). In The Lancet, Joy Tsai and colleagues r...

Combination of osteoporosis drugs 'better than either on its own'

A combination of the drugs teriparatide and denosumab appears to be better at increasing bone mineral density in postmenopausal women with the bone-thinning disease osteoporosis than either drug on it...

Is human enhancement cheating?

In 2013, neither Barry Bonds nor Roger Clemens made the Baseball Hall of Fame, even with their clearly superior records, because they used steroids. This was despite the fact that, as a New York Times...

Treating to a target 'more effective than routine care' in rheumatoid arthritis

Patients with active rheumatoid arthritis may achieve better outcomes by treating them with a view to achieving a specific target, rather than merely providing routine care, a study has found.Canadian...

Steroids Tied to Local Reactions to Yellow Fever 17D Vaccine

Patients receiving systemic corticosteroids seem to be at particular risk for local reactions to the yellow fever 17D vaccine, French researchers say. Reuters Health Information

Steroids, Relapse Predict Damage from Vasculitis (CME/CE)

(MedPage Today) -- BIRMINGHAM, England -- Patients with systemic vasculitis who require steroids for long periods or who have multiple relapses are likely to have extensive, irreversible organ damage,...

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Companies [ 3 Associated Companies listed on BioPortfolio]

Medical Research Institute

MRI is the leader in innovative sports nutrition products with a focus on combining science-based, unique active ingredients with highly efficient nutrient-delivery technologies e...

PsiOxus Therapeutics, Ltd.

PsiOxus Therapeutics is a development stage biotechnology company using non-traditional approaches to develop novel therapeutics that address cancer and other clinically un...

Forbes Medi-Tech

Forbes seeks to be a leader in delivering scientifically proven health benefits to consumers through innovative products derived from nature. The Company believes that consumers are increasingly looki...

Clinical Trials [ 293 Associated Clinical Trials listed on BioPortfolio]

Anabolic and Inflammatory Responses to Short-Term Testosterone Administration in Older Men

Skeletal muscle loss is a common consequence of aging and in some individuals reaches a level that compromises health and quality of life. Age-associated increases in cytokine and inflamm...

The Effects of Anabolic Steroids and Protease Inhibitors on People Living With HIV/AIDS

The main aim of the study is to investigate the combined effects of using anabolic steroids and protease inhibitors on fat metabolism and body composition of People Living with HIV/AIDS....

A Study to Evaluate the Safety and Efficacy of FK506E (MR4) in Patients Undergoing Primary Liver Transplantation.

To evaluate and to compare efficacy and safety of a dual regimen with oral modified release tacrolimus FK506E (MR4) / steroids versus a dual regimen with oral tacrolimus FK506 / steroids i...

Dexamethasone for Palliation - Brain Metastases

Brain metastases occur when cancer cells from the initial tumour site (for example, lung or breast) spread to the brain. This develops in approximately 10% - 30% of adults with cancer. Th...

"PTHrP(1-36) IV Dose Escalation Study"

This is a single-blinded, one-treatment, combination dose escalation and pharmacokinetic study done in healthy volunteers. The investigators want to determine whether PTHrP(1-36) shares a...

Bone Density and Serum Testosterone in Male Methadone Maintained Patients

This is a pilot study designed to answer the question " Do men who are receiving methadone maintenance therapy have lower spinal bone densities compared with age-matched controls who are n...

Placebo Versus Antibiotics in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)

The role of antibiotic therapy in patients with COPD remains controversial. While the outcome of several clinical trials is in favour of antibiotics, the quality of these studies in insuff...

VIP: Vascular Imaging Project. Study on the Progression of Cardiovascular Disease in Renal Transplant Recipients

This is a prospective randomized study to compare the influence of area under the curve (AUC)-monitored dual treatment with steroids in combination with either a calcineurin inhibitor (CNI...

A Trial of Two Steroid-Free Approaches Toward Mycophenolate Mofetil-Based Monotherapy Immunosuppression

This is an open label, single-center, randomized phase IV pilot study of steroid and calcineurin inhibitor avoidance in renal transplant recipients. All patients will receive two doses of...

Biomarkers of iNOS Activity in COPD, Asthma, Healthy Control

This pilot study will measure the baseline levels and the intra- and inter-subject variability of exhaled (alveolar and bronchial) and nasal NO in smoking subjects with mild and moderate C...

Medical and Biotech [MESH] Definitions

Clerodendrum

A plant genus of the family VERBENACEAE. Inerminosides (iridoid glycosides); colebroside A; STEROIDS; STEROLS; terpenoid glucosides; and abietane DITERPENES have been found in this genus.

Steroid 16-alpha-hydroxylase

A liver microsomal cytochrome P450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme is encoded by a number of genes from several CYP2 subfamilies.

Estrogenic Steroids, Alkylated

Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other position. 17-alpha-ALKYLATION renders the molecule more stable, resistant to metabolic degradation, and improves oral efficacy. Examples of synthetic alkyl estrogens include ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic and cytotoxic properties.

Alkane 1-monooxygenase

A P450 oxidoreductase that catalyzes the hydroxylation of the terminal carbon of linear hydrocarbons such as octane and FATTY ACIDS in the omega position. The enzyme may also play a role in the oxidation of a variety of structurally unrelated compounds such as XENOBIOTICS, and STEROIDS.

Steroid Metabolism, Inborn Errors

Errors in metabolic processing of STEROIDS resulting from inborn genetic mutations that are inherited or acquired in utero.

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