Anal Fissure - Biotech, Pharma and Life Science Channel
PubMed Articles
Hypermethylation and prognostic implication of Syk gene in human colorectal cancer.
The study was aimed to investigate the relationship between hypermethylation of Syk gene and clinicopathological characteristics and long-term outcomes in colorectal cancer. The effect of Syk on cell...
Native CuA redox sites are largely resilient to pH variations within a physiological range.
Previous studies on engineered CuA centres have shown that one of the histidine ligands is protonated and dissociated from the metal site at physiological pH values, thus suggesting a role in regulati...
A methodology based on second-order data (excitation emission matrices) modeling with one of most popular algorithms presenting the second-order advantage, parallel factor analysis (PARAFAC), combined...
RuBiGABA-2: a hydrophilic caged GABA with long wavelength sensitivity.
We have devised a new caged GABA based on ruthenium bipyridyl coordination chemistry. This phototrigger delivers GABA upon irradiation with wavelengths up to 532 nm undergoing heterolytic photocleavag...
Young men who have sex with men (YMSM) are disproportionately infected with HIV/AIDS and there are few prevention programs with published efficacy for this population. This study evaluated the feasibi...
PURPOSE: The sigmoidorectal junction (SRJ) has been defined as an anatomical sphincter with particular physiological behavior that regulates sigmoid and rectum evacuation. Its function in clinical con...
AIM: The short term outcome was examined of perineal vertical rectus abdominis myocutaneous (VRAM) flap reconstruction following abdominal perineal excision (APE). METHOD: Retrospective case note revi...
This study compared the correlates of HIV risk among men who have sex with men (MSM) with newly diagnosed versus previously known HIV infection among 5,148 MSM recruited using modified snowball sampli...
A new perspective of three-dimensional voltammetry is given for the study of metal complexation in the presence of adsorption phenomena and, eventually, when the electrochemical reversibility of the p...
Morphometry of the soft tissues of the orbital region in Northern Sudanese persons.
The orbital region plays a predominant role in the evaluation of the craniofacial complex. No current normative data exist for Northern Sudanese subjects. In the current study information about normal...
News Articles
Merck (NYSE: MRK), known as MSD outside the United States and Canada, announced today that the company has been awarded a significant portion of the UNICEF human papillomavirus (H...
Newest Condom Designed for Sodomy Will Be Released on 2015
Origami Condoms from California is now planning to release the very first condom specially designed for anal sex to the market in 2015. The company unveiled the prototypes for receptive anal intercour...
Newest Condom Designed for Gay Couples Will Be Released on 2015
Origami Condoms from California is now planning to release the very first condom specially designed for anal sex to the market in 2015. The company unveiled the prototypes for receptive anal intercour...
Rectal cancer: Chemoradiation for anal cancer: cisplatin or mitomycin?
Anal Cancer Rates Appear to Be On the Rise in the U.S.
The number of people in the United States with anal cancer has tripled since the 1970s, according to the results of a study published in the Journal of Clinical Oncology. Anal cancer is an uncommon ty...
Advaxis Announces Promotion of Dr. Robert Petit and Daniel J. O’Connor
Advaxis, Inc., (OTCBB: ADXS), a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that the Board of Directors of Adv...
Advaxis Announces 2013 Annual Meeting of Stockholders
Advaxis, Inc., (OTCBB: ADXS), a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that its Annual Meeting of Stockho...
Exclusion diet boosts anal fissure healing
Research published in the American Journal of Gastroenterology shows that an exclusion diet combined with medical treatment can increase healing rates in patients with chronic anal fissure who have be...
Brachytherapy Shows Promise in Anal Canal Cancer
In patients with anal canal cancer, a brachytherapy boost after radiotherapy or chemoradiotherapy allows high local control rates with acceptable toxicity. Medscape Medical News
Chemotherapy: Final ACT for standard of care in anal cancer?
Events
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Companies
S.L.A. Pharma AG is a privately owned Swiss company pioneering the development of speciality pharmaceutical products for gastrointestinal and rare disorders. Their pipeline consis...
Clinical Trials
RATIONALE: Octreotide may be effective in preventing or controlling diarrhea in patients who are undergoing chemoradiotherapy for anal or rectal cancer. It is not yet known whether octreot...
Infrared Coagulation in Preventing Anal Cancer in Patients With HIV Who Have Anal Neoplasia
RATIONALE: Infrared coagulation may be effective in preventing the development of anal cancer in patients who have anal neoplasia. PURPOSE: Pilot study to evaluate the effectiveness of in...
Vaccine Therapy in Treating Patients With Advanced or Recurrent Cancer
RATIONALE: Vaccines made from certain human papillomaviruses may be able to help the body to kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of human papillomavi...
BACKGROUND: A number of important scientific advances can be made through the study of blood, bone marrow, tumor, or other tissue samples from patients with HIV infection, infection with K...
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Com...
Oxaliplatin Plus Irinotecan in Treating Patients With Metastatic Gastrointestinal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Ph...
Interleukin-12 in Treating Patients With Cancer in the Abdomen
RATIONALE: Interleukin-12 may kill tumor cells by stimulating a person's white blood cells to kill cancer cells. PURPOSE: Phase I trial to study the effectiveness of interleukin-12 in tre...
PRIMARY: In Phase I, to define a broadly tolerable dose of isotretinoin that can be used in combination with interferon alfa-2a (IFN alfa-2a). In Phase II, to determine trends in efficacy...
To determine the safety, effectiveness, and toxicity of topical (local) trifluridine in treating mucocutaneous (at the nasal, oral, vaginal, and anal openings) Herpes simplex virus ( HSV )...
Anal fissure is a solitary ulcer in the squamous epithelium of the anus causing intense anal pain especially upon defecation and for one or two hours afterwards. There are no approved drug...
Videos
Anal Fissure
Darren Pollock, MD, discusses what an anal fissure is and ways you can treat it.
Medical and Biotech [MESH] Definitions
Mustelidae
A family of terrestrial carnivores with long, slender bodies, long tails, and anal scent glands. They include badgers, weasels, martens, FERRETS; MINKS; wolverines, polecats, and OTTERS.
Trichosurus
A genus of brush-tailed possums found chiefly in Australia and New Zealand. Secretions from their ANAL GLAND function both in defense and demarcating territory.
Pallister-hall Syndrome
A pleiotropic disorder of human development that comprises hypothalamic HAMARTOMA; central and postaxial POLYDACTYLY; bifid EPIGLOTTIS; ANAL ATRESIA; and renal and other abnormalities. This disorder is associated with FRAMESHIFT MUTATIONS in the GLI3 gene which encodes the GLI3 protein, a KRUPPEL-LIKE TRANSCRIPTION FACTORS family member.
Pterygopalatine Fossa
A small space in the skull between the MAXILLA and the SPHENOID BONE, medial to the pterygomaxillary fissure, and connecting to the NASAL CAVITY via the sphenopalatine foramen.
Pruritus Ani
Intense chronic itching in the anal area.
