Androgenetic alopecia - Biotech, Pharma and Life Science Channel
PubMed Articles
Generalized Alopecia with Vasculitis-Like Changes in a Dog with Babesiosis.
A locally bred, 12-year-old, intact female Satsuma dog presented with generalized alopecia. Erythema, crusts and desquamation were observed primarily on the truck. Papules and erosions were present in...
BACKGROUND: The WSP tool has previously been proposed as a method to detect signals for adverse drug reactions utilising time-to-event data without the need for a reference population. The aim of this...
PURPOSE As part of the ENTHUSE (Endothelin A Use) program, the efficacy and safety of zibotentan (ZD4054), an oral specific endothelin A receptor antagonist, has been investigated in combination with...
Androgen-related diseases impair the well-being of many aging men. Unfortunately, the medications used to treat these diseases have many side effects. Therefore, there is a significant need for the de...
Stem cells and small molecule screening: haploid embryonic stem cells as a new tool.
Stem cells can both self-renew and differentiate into various cell types under certain conditions, which makes them a good model for development and disease studies. Recently, chemical approaches have...
PURPOSE: Chemotherapy-induced alopecia is very distressing for a patient and may have an impact on treatment decisions. On docetaxel-based therapy, alopecia occurs in a substantial proportion of patie...
The contribution of endogenous and exogenous factors to male alopecia: a study of identical twins.
: The purpose of this study was to investigate the potential contribution of environmental factors and testosterone on male alopecia.
Association analysis of the HLA-C gene in Japanese alopecia areata.
Alopecia areata (AA) is an organ-specific and cell-mediated autoimmune disease involving hair loss, but its pathogenesis remains poorly understood. Many autoimmune diseases are genetically associated...
IMAGING DIAGNOSIS: FIBRODYSPLASIA OSSIFICANS PROGRESSIVA IN A CAT.
A 1-year-old female cat was presented for progressive alopecia, gait abnormalities, and stiffness. Radiography demonstrated multiple calcified lesions within the soft tissues of the cervical and thora...
Acquired alopecia in childhood.
Hair loss and alopecia occur frequently in children. The prevalence of the underlying causes and conditions, treatment options and prognosis differ in part significantly from adulthood. This article f...
News Articles
Biologix Hair Inc. Appoints Mark Maybank to its Board of Directors
TORONTO, ONTARIO -- (Marketwired) -- 05/17/13 -- Biologix Hair Inc. (OTCBB: BLGX) (OTCQB: BLGX) has appointed Mark Maybank to the Company's Board of Directors. Mr. Maybank will serve as an independen...
TORONTO, ONTARIO -- (Marketwired) -- 05/15/13 -- Biologix Hair Inc. (OTCBB: BLGX) (OTCQB: BLGX) has appointed Dr. Michael Stocker as Chief Executive Officer and to the Company's Board of Directors an...
Biologix Hair Inc. Appoints Ken Zadoorian to Board of Directors
TORONTO, ONTARIO -- (Marketwired) -- 05/13/13 -- Biologix Hair Inc. (OTCBB: BLGX) (OTCQB: BLGX) has appointed Ken Zadoorian to the Company's Board of Directors. Mr. Zadoorian will serve as an indepen...
TORONTO, ONTARIO -- (Marketwired) -- 05/09/13 -- Biologix Hair Inc. (OTCBB: BLGX)(OTCQB: BLGX) has appointed David Perez-Meza, MD to the Company's Medical Advisory Board, where he will serve with Dr...
TORONTO, ONTARIO -- (Marketwired) -- 05/08/13 -- Biologix Hair Inc. (OTCBB: BLGX) (OTCQB: BLGX) has appointed William A. Keller to the Company's Board of Directors. Wilhelm A. Keller is the founder...
TORONTO, ONTARIO -- (Marketwired) -- 05/07/13 -- Biologix Hair Inc. (OTCBB: BLGX) (OTCQB: BLGX) has appointed Alan J. Bauman, MD to its Medical Advisory Board, where he will serve with Dr. Edward A.M...
Viviscal Presents Supplements for First Time at World Hair Congress
CHICAGO, May 6, 2013 /PRNewswire/ -- Viviscal®, the world's leading brand of dietary supplements announces its participation in the 7th annual World Hair Congress in Edinburgh, Scotland. Taking p...
TORONTO, ONTARIO -- (Marketwired) -- 05/06/13 -- Biologix Hair Inc. (OTCBB: BLGX)(OTCQB: BLGX) has appointed Dr. Pankaj Modi to its Board of Directors and as Vice President of Research and Developmen...
VANCOUVER, BRITISH COLUMBIA -- (Marketwired) -- 05/03/13 -- RepliCel Life Sciences Inc. (the "Company" or "RepliCel") (OTCBB: REPCF)(CNSX: RP) reports that its Chief Scientific Officer, Dr. Kevin Mc...
Blocking Potassium Channels (Kv1.3): A New Treatment Option for Alopecia Areata?
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Clinical Trials
Ultraviolet (UVA and UVB) Light Therapy in the Treatment of Inflammatory Skin Conditions
The purpose of this investigation is to study the effectiveness of longer wavelength UVA1 (340-400nm) or shorter wavelength ultraviolet B [UVB] (290-320nm) irradiation in the treatment of...
Treatment of the Recessive Nonbullous Congenital Ichthyosis by the Epigallocatechine Cutaneous
Lamellar ichthyosis (IL) is a rare autosomal recessive genodermatosis with a defect of keratinization of the skin which results in a severe generalized cutaneous xerosis with dark brown bi...
Dose-Ranging Efficacy Study of Topical NEOSH101 to Treat Male Pattern Hair Loss
The purpose of this study is to evaluate the safety and efficacy of three doses of topical NEOSH101 applied once-daily (qd) for 16 weeks in men with thinning hair in the top and center of...
Aldara for the Treatment of Extensive Alopecia Areata
We propose to examine the efficacy and tolerability of Aldara Cream 5% for the treatment of extensive alopecia areata. Aldara is a immune-response modifier. The drug induces the producti...
Response of Topical Capsaicin in Alopecia Areata
It has been postulated that Alopecia Areata (AA) is, at least in part, a neurologically mediated disease. Research supporting this theory includes the finding that nerves surrounding the...
Characteristics of T Cells From Alopecia Areata Scalp Skin Before and After Treatment With Aldara 5%
It is thought that alopecia areata occurs as the result of an inappropriate response of the body's own immune system to certain substances in or around the hair follicle. We will be exami...
Alefacept in Patients With Severe Scalp Alopecia Areata
The purpose of this study is to examine prospectively the safety and efficacy of alefacept in the treatment of subjects with severe alopecia areata of the scalp. Common features between p...
The primary purpose of the study is to evaluate the efficacy of a topical 5% minoxidil formulation in males for the treatment of pattern hair loss. The secondary purpose is to evaluate th...
Prevention of Persistent Alopecia Following Docetaxel by Means of Scalp Cooling
Persistent alopecia following adjuvant docetaxel for breast cancer is a side-effect that has been recently described. Docetaxel is toxic to skin and skin annexes and can produce nail toxic...
The aim of this Phase III study is to compare the efficacy, safety and tolerability of dutasteride (0.5mg) with placebo for 6 months, in Korean male subjects with androgenetic alopecia in...
Videos
Androgenetic Alopecia
I have been slowly going bald since I was 16. I'm 34 now and I cant hide it as well. Will probably get a wig, because its come to that point. I cant imagine ...
Medical and Biotech [MESH] Definitions
Monilethrix
Rare autosomal dominant disorder of the hair shaft. The clinical features of the disease include HYPOTRICHOSIS, dry, and/or brittle hair, with varying degrees of ALOPECIA. Mutations in the hair-specific keratin genes KRTHB1, KRTHB3, or KRTHB6 are associated with monilethrix. Autosomal recessive monilethrix with limited HYPOTRICHOSIS are also known. Mutations in Dsg4, Liph, and P2ry5 protein genes are associated with the recessive form of monilethrix.
Loose Anagen Hair Syndrome
Benign childhood alopecia that improves spontaneously with aging. It is characterized by anagen hairs (misshapen hair bulbs and absent inner and outer root sheaths), thin, and sparse hairs that pulls out easily.
Uveomeningoencephalitic Syndrome
A syndrome characterized by bilateral granulomatous UVEITIS with IRITIS and secondary GLAUCOMA, premature ALOPECIA, symmetrical VITILIGO, poliosis circumscripta (a strand of depigmented hair), HEARING DISORDERS, and meningeal signs (neck stiffness and headache). Examination of the cerebrospinal fluid reveals a pattern consistent with MENINGITIS, ASEPTIC. (Adams et al., Principles of Neurology, 6th ed, p748; Surv Ophthalmol 1995 Jan;39(4):265-292)
Pyruvate Dehydrogenase Complex Deficiency Disease
An inherited metabolic disorder caused by deficient enzyme activity in the PYRUVATE DEHYDROGENASE COMPLEX, resulting in deficiency of acetyl CoA and reduced synthesis of acetylcholine. Two clinical forms are recognized: neonatal and juvenile. The neonatal form is a relatively common cause of lactic acidosis in the first weeks of life and may also feature an erythematous rash. The juvenile form presents with lactic acidosis, alopecia, intermittent ATAXIA; SEIZURES; and an erythematous rash. (From J Inherit Metab Dis 1996;19(4):452-62) Autosomal recessive and X-linked forms are caused by mutations in the genes for the three different enzyme components of this multisubunit pyruvate dehydrogenase complex. One of the mutations at Xp22.2-p22.1 in the gene for the E1 alpha component of the complex leads to LEIGH DISEASE.
Alopecia
Absence of hair from areas where it is normally present.
