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Antibiotic therapy - Biotech, Pharma and Life Science Channel

07:47 EDT 28th May 2016 | BioPortfolio

PubMed Articles [10740 Associated PubMed Articles listed on BioPortfolio]

Carbon dioxide dialysis in a swine model utilizing systemic and regional anticoagulation.

Extracorporeal carbon dioxide removal (ECCO2R) has been gaining interest to potentially facilitate gas transfer and equilibrate mild to moderate hypercapnic acidosis, when standard therapy with non-in...

Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy.

scVEGF/(177)Lu is a novel radiopharmaceutical targeted by recombinant single-chain (sc) derivative of vascular endothelial growth factor (VEGF) that binds to and is internalized by vascular endothelia...

Pre-clinical evaluation of eight DOTA coupled gastrin-releasing peptide receptor (GRP-R) ligands for in vivo targeting of receptor-expressing tumors.

Overexpression of the gastrin-releasing peptide receptor (GRP-R) has been documented in several human neoplasms such as breast, prostate, and ovarian cancer. There is growing interest in developing ra...

Development of chitosan/β-glycerophosphate/glycerol hydrogel as a thermosensitive coupling agent.

This work develops a dual-function thermosensitive hydrogel to prevent overheating, a side effect of focused ultrasound therapy. The proposed hydrogel has the components of chitosan, β-glycerophospha...

Prilling and supercritical drying: A successful duo to produce core-shell polysaccharide aerogel beads for wound healing.

Bacterial infections often affect the wound, delaying healing and causing areas of necrosis. In this work, an aerogel in form of core-shell particles, able to prolong drug activity on wounds and to be...

Synthesis and characterization of extremely small gold nanoshells, and comparison of their photothermal conversion capacity with gold nanorods.

The current methods for preparing gold nanoshells (AuNSs) produce shells with a diameter of approximately 40 nm or larger, with a relatively large polydispersity. However, AuNSs with smaller diameters...

Stereotactic Body Radiation Therapy for Oligometastatic Prostate Cancer.

To review outcomes of patients with oligometastatic prostate cancer (PCa) treated with stereotactic body radiation therapy (SBRT) and to identify variables associated with local failure.

Predictors of Fatigue Impact in Persons With Long-Standing Multiple Sclerosis.

Fatigue is a common experience among persons diagnosed with multiple sclerosis (MS). Fatigue negatively influences quality of life, interferes with activities of daily living, and impairs the ability ...

Multiple long bone fractures in a child with pycnodysostosis. A case report.

Fractures are an important entity to consider in pediatric patients. There are certain diseases in which bones fracture with a minimal trauma. Pycnodysostosis is an autosomal recessive unusual type of...

Anticoagulant and vasodilator therapy for Nicolau syndrome following intramuscular benzathine penicillin injection in a 4 year old boy.

Nicolau syndrome (NS) is a rare complication of intramuscular, intraarticular or subcutaneous injection of particular drugs leading to ischemic necrosis of the surrounding skin, soft tissue and muscul...

News Articles [6631 Associated News Articles listed on BioPortfolio]

Global Radiotherapy Market is Expected to Reach USD 8.1 Billion by 2022, Owing to the Growing Incidence of Cancer - a New Report by Data Bridge Market Research

Dallas, TX, May 28, 2016 --(PR.com)-- The global radiotherapy market has accounted for USD 4.9 billion in 2015, and is expected to reach USD 8.1 billion by 2022, growing at a CAGR 7.1% during the for...

Invokana superior to glimepiride for glycemic control, weight loss, BP

ORLANDO, Fla. — Over 52 weeks, glycemic control was improved and body weight and blood pressure were reduced with Invokana as add-on therapy to metformin in patients with type 2 diabetes, according ...

New incentives needed to develop antibiotics to fight superbugs

NEW YORK, May 27 (Reuters) - Drugmakers are renewing efforts to develop medicines to fight emerging antibiotic-resistant bacteria, but creating new classes of drugs on the scale needed is unlikely to...

Dangerous New Antibiotic-Resistant Bacteria Reach U.S.

Woman infected with microbes that fight a last-line-of-defense drug; common infections could become untreatable -- Read more on ScientificAmerican.com

High prevalence of radiographic vertebral fractures found among patients with ankylosing spondylitis

Patients with active ankylosing spondylitis had a high prevalence of radiographic vertebral fractures, according to results.Of 173 patients with ankylosing spondylitis enrolled in the Groningen Leeuwa...

References

1 National Cancer Institute FactSheet. Herceptin® (Trastuzumab): Questions and Answers. Available at:http://www.cancer.gov/cancertopics/factsheet/therapy/herceptin. Accessed October 11, 2007. 2 Hob...

Chemotherapy for Recurrent Breast Cancer

Patients with recurrent cancer may have already received chemotherapy as their initial treatment or recently stopped responding to hormonal therapy.  if the first chemotherapy drug (or combination of...

EC approves GSK's Strimvelis

GlaxoSmithKline plc (LSE:GSK; NYSE:GSK) said the European Commission approved gene therapy Strimvelis (GSK2696273) to treat patients with severe combined immunodeficiency due to adenosine deaminase de...

CHMP recommends HCV combos, spurns Ninlaro

EMA's CHMP recommended approval of HCV therapies from Gilead Sciences Inc. (NASDAQ:GILD) and Merck & Co Inc. (NYSE:MRK), but recommended against approving cancer compound Ninlaro ixazomib from Takeda ...

Myeloma Drug Access Limits Unlikely Near-term – Aetna, Express Scripts Say

ICER’s cost-effectiveness assessment won't lead to place step therapy restrictions on sequence of multiple myeloma treatment regimens – at least until there's better data.

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Companies [341 Associated Companies listed on BioPortfolio]

Hocoma

A successful therapy begins in patients’ heads. In the firm belief that – step by step – they can reach their goals and regain quality of life.

Apria Healthcare Group Inc.

Apria is a privately held company owned by a group of investment limited partnerships managed by affiliates of Blackstone (NYSE:BX). Through its Apria Healthcare LLC operating uni...

PromptCare

PromptCare® is a leading regional provider of specialty respiratory products and infusion therapy services. Established in 1985 and headquartered in Clark, New Jersey, PromptCa...

Arsanis, Inc.

Arsanis is committed to the development of monoclonal antibody therapeutics against severe infectious diseases that cannot be controlled with currently available medical treatment...

MOLOGEN AG

MOLOGEN is specializing in selected areas of Molecular Medicine. Our areas of competence are gene expression, gene therapy and bioinformatics. We are dedicated to the development of DNA expression and...

TOMTEC

Tomtec has succeeded since 1967 by working with its clients to help solve their liquid handling needs. From 1967 to 1981, the Company had essentially one employee, Tom Astle. From 1967 to 1971, the Co...

Inogen, Inc.

Inogen is innovation in oxygen therapy. We are a medical technology company that develops, manufactures and markets innovative oxygen concentrators used to deliver supplemental lo...

Hereditary Neuropathy Foundation

Hereditary Neuropathy Foundation (HNF) is a non-profit 501(c)3 organization whose mission is to increase awareness and accurate diagnosis of Charcot-Marie-Tooth disease (CMT) and ...

Telephus Medical LLC

Telephus Medical, located in San Diego, California, is developing a suite of monoclonal antibody products designed to neutralize key staphylococcal enzymes used to attach to host ...

Soterix Medical, Inc.

Soterix Medical PainXTM Therapy is a non-systemic (does not circulate in the bloodstream throughout the body) and non-invasive (does not involve surgery) form of neuromodul...

Clinical Trials [1591 Associated Clinical Trials listed on BioPortfolio]

An Oral Amoxicillin-Clavulanate Regimen to Prevent Bacteremia Following Dental Procedures

Although controversy exists regarding the efficacy of antibiotic prophylaxis for patients at risk of infective endocarditis, expert committees continue to publish recommendations for antib...

Cognitive Behavioral Therapy for Insomnia for Gulf War Illness

Sleep disturbance is a common complaint of Veterans with Gulf War Illness (GWI). Because there is clinical evidence that sleep quality influences pain, fatigue, mood, cognition, and daily ...

The Application of Negative Atrioventricular Hysteresis in Cardiac Resynchronization Therapy With MultiPoint Pacing

The purpose of this study is to evaluate the application of Negative AV Hysteresis (NAVH) to improve electrical synchrony in MultiPoint Pacing (MPP) Cardiac Resynchronization Therapy (CRT)...

Safety and Efficacy of Fecal Microbiome Transplantation (FMT) in the Treatment of Antibiotic Dependent Pouchitis (ADP)

Antibiotic dependent pouchitis (ADP) is predestined to benefit from FMT, since bacterial dysbiosis, which can only be controlled with antibiotics, appears to be the major driver of the cli...

Standardized Treatment of Pulmonary Exacerbations II

Cystic fibrosis (CF), a life-shortening genetic disease, is marked by acute episodes during which symptoms of lung infection increase and lung function decreases. These pulmonary exacerbat...

Nivolumab and Stereotactic Ablative Radiation Therapy Versus Nivolumab Alone for Metastatic Renal Cancer

Nivolumab (brand name Opdivo): IV, 3 mg/kg q2 weeks, until disease progression or unacceptable toxicity; SAbR, dose variable, in 1-3 fractions to multiple metastatic sites.

Comparing Unimanual and Bimanual Mirror Therapy for Upper Limb Recovery Post Stroke

The purpose of this randomized controlled study is to 1. Examine the feasibility of a home Mirror therapy (MT) program in the NYC metropolitan area; 2. Evaluate the effect...

Pharmacokinetic and Therapeutic Adaptation of Linezolid in the Treatment of Multi-Resistant Tuberculosis

Linezolid, primary treatment for MDR-TB combination therapy anti. Until it is the dose of 600 mg x1 / day, rather sensible for most patients is more, which was unanimous. It is true that i...

Integrative Cardiac Health Project Cognitive-Behavior Therapy for Insomnia

This study investigates the feasibility, acceptability, and effectiveness of adding Cognitive-Behavioral Therapy for Insomnia (CBT-I) to the standard care received at the Integrative Cardi...

Mirror Therapy After Stroke: A Dosing Study

It has been suggested that augmenting repetitive task practice with the use of box (mirror) therapy (BT) can enhance the benefits of task practice and may provide stroke survivors an oppor...

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Medical and Biotech [MESH] Definitions

A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.

Preliminary cancer therapy (chemotherapy, radiation therapy, hormone/endocrine therapy, immunotherapy, hyperthermia, etc.) that precedes a necessary second modality of treatment.

The presence of fungi circulating in the blood. Opportunistic fungal sepsis is seen most often in immunosuppressed patients with severe neutropenia or in postoperative patients with intravenous catheters and usually follows prolonged antibiotic therapy.

A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.

A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.

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