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Antibiotic therapy - Biotech, Pharma and Life Science Channel

10:29 EDT 30th March 2017 | BioPortfolio

PubMed Articles [11251 Associated PubMed Articles listed on BioPortfolio]

Precision medicine in immune checkpoint blockade therapy for non-small cell lung cancer.

Immune checkpoint blockade therapy by targeting the programmed death protein 1/programmed death ligand 1 (PD-L1) axis using antibodies has yielded promising clinical responses in patients with non-sma...

Non-invasive Photodynamic Therapy in Brain Cancer by Use of Tb(3+)-Doped LaF3 Nanoparticles in Combination with Photosensitizer Through X-ray Irradiation: A Proof-of-Concept Study.

The use of photodynamic therapy (PDT) in the treatment of brain cancer has produced exciting results in clinical trials over the past decade. PDT is based on the concept that a photosensitizer exposed...

Usefulness of a laparoscopic approach for treatment of small-bowel obstruction due to intersigmoid hernia: a case report.

It is well known that intersigmoid hernia (ISH) is a rare condition. Here we describe our experience of laparoscopic surgery for small-bowel obstruction (SBO) due to ISH after sufficient decompression...

Two cases of resectable pancreatic cancer diagnosed by open surgical biopsy after endoscopic ultrasound fine-needle aspiration failed to yield diagnosis: case reports.

Tumor biopsy for histological diagnosis is required preoperatively and before initiating chemotherapy or radiation therapy for patients with pancreatic cancer (Cancer of the Pancreas: Clinical Practic...

Blood perfusion in osteomyelitis studied with (15)Owater PET in a juvenile porcine model.

Osteomyelitis is a serious disease which can be difficult to treat despite properly instituted antibiotic therapy. This appears to be related at least partly to degraded vascularisation in the osteomy...

Management of respiratory tract infections in young children-A qualitative study of primary care providers' perspectives.

Respiratory tract infections in young children are the most common cause of general practice visits in Australia. Despite the availability of clinical practice guidelines, the treatment and management...

Seek and destroy: targeted adeno-associated viruses for gene delivery to hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer with high incidence globally. Increasing mortality and morbidity rates combined with limited treatment options available ...

Nanocarriers as treatment modalities for hypertension.

Hypertension, a worldwide epidemic at present, is not a disease in itself rather it is an important risk factor for serious cardiovascular disorders including myocardial infarction, stroke, heart fail...

Effective improvement of the neuroprotective activity after spinal cord injury by synergistic effect of glucocorticoid with biodegradable amphipathic nanomicelles.

Dexamethasone acetate (DA) produces neuroprotective effects by inhibiting lipid peroxidation and inflammation by reducing cytokine release and expression. However, its clinical application is limited ...

Targeting delivery of simvastatin using ICAM-1 antibody-conjugated nanostructured lipid carriers for acute lung injury therapy.

Acute lung injury (ALI) is a critical illness without effective therapeutic modalities currently. Recent studies indicated potential efficacy of statins for ALI, while high-dose statins was suggested ...

News Articles [6442 Associated News Articles listed on BioPortfolio]

FDA Grants Priority Review to Novartis's CAR-T Cell Therapy

NewsThe priority review designation is expected to shorten the anticipated review time by the FDA.

DermOne CMO Dr. Andrew Krakowski to Present at Annual Conference of the American Society for Laser Medicine and Surgery

Dr. Krakowski will present cutting edge techniques for scar therapy and pediatric laser treatment DermOne LLC today announced that Chief Medical Officer, Andrew C. Krak...

Kite to Present Two Plenary Presentations from the ZUMA-1 Pivotal Trial of Axicabtagene Ciloleucel at the 2017 American Association of Cancer Research Annual Meeting

Plenary Presentation on Positive Primary Analysis of the ZUMA-1 Pivotal CAR-T Trial in Patients with Aggressive Non-Hodgkin Lymphoma Plenary and Oral Pre...

Global Alpha Emitters Market by Type and Application Industry Analysis, Size, Share, Growth Trends and Forecasts 2016 2021 [Updated: 01122016] Prices from USD $4255

The global market for alpha emitters is currently estimated to be valued at $107 million for the year 2015 and is poised to reach $283 million by the end of 2020. The CAGR during this period of foreca...

GMO plant emerges as drug incubator to fight malaria

Novartis CAR-T cell therapy BLA accepted for FDA priority review

The US Food and Drug Administration has accepted the Biologics License Application (BLA) filing and granted…

Novartis gets speedy review for CAR-T cell therapy

Novartis has stepped ahead in the race to get the first cancer-killing CAR-T cell therapy on the market having successfully filed a biologics license application with US regulators.

Merck signs up UK’s Avillion to develop psoriasis therapy

Merck has signed a collaboration agreement with the UK’s Avillion under which the latter will develop the German drug giant’s anti IL-17 A/F Nanobody as a treatment for plaque psoriasis.

Corbus drug shows promise as add-on therapy for cystic fibrosis

(Reuters) - An anti-inflammatory drug being developed by Corbus Pharmaceuticals Holdings as an add-on treatment for cystic fibrosis demonstrated promising safety and was well tolerated in a small mids...

Solid Biosciences Raises up to $50 Million in Series C Financing

-Company to Use Proceeds to Advance Programs for Duchenne Muscular Dystrophy- Solid Biosciences announced today that it has completed the initial closing of its $50 Mil...

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Companies [346 Associated Companies listed on BioPortfolio]

ProCure Proton Therapy Center in New Jersey

MedAutonomic

MedAutonomic is a privately held medtech company dedicated to developing a bioelectric medicine to treat patients with functional diseases of the metabolic syndrome such as type-2...

R-JAPAN Co., Ltd.

R-JAPAN Co., Ltd. is the advanced biotechnology company specialized in manufacturing mesenchymal stem cells regenerative therapy with stem cell technology of Biostar Stem c...

PharmaCord LLC

An independently owned company, PharmaCord provides services to biopharma manufacturers supporting the commercialization of specialty products. The company is the connector betwee...

Merz Pharmaceuticals

Merz Pharmaceuticals, LLC is a part of Merz, Inc., a wholly owned U.S. subsidiary of the Merz Group of Companies and was established in 1995 to develop and commercialize products for the Merz Group. ...

Insulet Corporation

Insulet Corporation (NASDAQ: PODD) is an innovative medical device company dedicated to making the lives of people with diabetes easier. Through its Omnipod Insulin Management Sys...

Fusion Pharmaceuticals

Fusion Pharmaceuticals is a new pharmaceutical company located in Hamilton, Ontario, Canada focused on becoming the leader in the targeted alpha therapy field. Fusion will exploit...

Discuva

Discuva aims to revolutionise the treatment of disease caused by bacterial infection by discovering and developing new antibiotics against highly drug-resistant pathogens. The com...

BioScrip Inc.

BioScrip, Inc. is a leading national provider of infusion and home healthcare management solutions. BioScrip partners with healthcare providers, including physicians, hospital sys...

VisCardia Inc

VisCardia based in Portland, OR is developing a novel implantable device therapy for treating heart failure, a condition that afflicts 10 million patients in the U.S. and Europe. ...

Clinical Trials [1955 Associated Clinical Trials listed on BioPortfolio]

High Flow Nasal Cannula Therapy in Bronchiolitis : Early vs Rescue

The enrolled RSV-bronchiolitis patients will be randomized into two arms , the early HHHFNC group and the standard therapy group with rescue HHHFNC to study the efficacy of this treatment.

Decreasing Delirium Through Music

DDM is a study designed to Test the efficacy of personalized music therapy in reducing delirium incidence and severity among patients admitted to the Intensive Care Unit.

Vibratory PEP Device and Hospital Length of Stay for Acute Exacerbation of COPD

This study is evaluating the use of a respiratory device, the Acapella Vibratory Positive Expiratory Pressure (PEP) Therapy device, in patients admitted to the hospital with a chronic obst...

Psychomotor Therapy for Very Premature Infants

Our current reflexion is that sensory dys-stimulations, including vestibule-proprioceptive disorders and unbalanced between brain and brainstem maturation of the neonatal period involve an...

Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis

The aim of this randomized controlled clinical trial of superiority will be to evaluate the effect of 900 mg of omega-3 polyunsaturated fatty acids and 100 mg of aspirin daily supplementat...

Strategic Management to Optimize Response To Cardiac Resynchronization Therapy

The primary objective is to evaluate the benefit of the SmartDelay™ algorithm in patients with a prolonged RV-LV interval.

Phase IIa Clinical Study of N-Rephasin® SAL200

This study is performed to evaluate safety and to explore the efficacy of a single intravenous dose of N-Rephasin® SAL200 (3 mg/kg) in addition to the conventional standard treatment, for...

A B-D-GLUCAN DRIVEN ANTIFUNGAL STEWARDSHIP APPROACH TO MANAGE EMPIRICAL THERAPY IN PATIENTS AT VERY HIGH RISK FOR INVASIVE CANDIDIASIS: A RANDOMIZED CONTROLLED TRIAL

This is a multicenter, prospective, open-label, randomized trial. Patients with severe abdominal condition developing severe sepsis or septic shock and receiving broad spectrum antibiotic ...

Photodynamic Therapy With HPPH Compared to Standard of Care Surgery in Treating Patients With Oral Cavity Cancer

This randomized phase II clinical trial studies how well photodynamic therapy with HPPH works compared to standard of care surgery in treating patients with oral cavity cancer. Photodynami...

Impact of Cotrimoxazole Use in Immunocompetent HIV Patients on Carriage of Antimicrobial Resistant Bacteria

Cotrimoxazole preventive therapy (CPT) is recommended for prevention of morbidity and mortality due to Pneumocystis pneumonia and other infections in HIV positive patients with low immunit...

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Medical and Biotech [MESH] Definitions

A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.

Preliminary cancer therapy (chemotherapy, radiation therapy, hormone/endocrine therapy, immunotherapy, hyperthermia, etc.) that precedes a necessary second modality of treatment.

The presence of fungi circulating in the blood. Opportunistic fungal sepsis is seen most often in immunosuppressed patients with severe neutropenia or in postoperative patients with intravenous catheters and usually follows prolonged antibiotic therapy.

A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.

A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.

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