Antibiotic therapy - Biotech, Pharma and Life Science Channel

09:57 EDT 27th May 2015 | BioPortfolio

PubMed Articles [10236 Associated PubMed Articles listed on BioPortfolio]

Cost-effectiveness of stimulation of the sphenopalatine ganglion (SPG) for the treatment of chronic cluster headache: a model-based analysis based on the pathway CH-1 study.

In the recent Pathway CH-1 study, on-demand stimulation of the sphenopalatine ganglion (SPG) by means of an implantable neurostimulation system was proven to be a safe and effective therapy for the tr...

Design of a surface plasmon resonance immunoassay for therapeutic drug monitoring of amikacin.

The therapeutic drug monitoring (TDM) of pharmaceutical drugs with narrow therapeutic ranges is of great importance in the clinical setting. It provides useful information towards the enhancement of d...

Facilitating emotional processing in depression: the application of exposure principles.

Even with the best psychosocial and pharmacological treatments for unipolar depression, relapse is a serious problem. One path to improve treatments for depression is to target fundamental processes t...

Preface.

This special issue is dedicated to the 70th birthday of Glenn F. Webb. The topics of the 12 articles appearing in this special issue include evolutionary dynamics of population growth, spatio-temporal...

The Effect of Flattening Filter Free on Three-dimensional Conformal Radiation Therapy (3D-CRT), Intensity-Modulated Radiation Therapy (IMRT), and Volumetric Modulated Arc Therapy (VMAT) Plans for Metastatic Brain Tumors from Non-small Cell Lung Cancer.

Flattening filter free (FFF) may affect outcome measures of radiotherapy. The objective of this study is to compare the dosimetric parameters in three types of radiotherapy plans, three-dimensional co...

Are reactive oxygen species still the basis for diabetic complications?

Despite the wealth of pre-clinical support for a role for reactive oxygen and nitrogen species (ROS/RNS) in the aetiology of diabetic complications, enthusiasm for antioxidant therapeutic approaches h...

Co-delivery of doxorubicin and tumor-suppressing p53 gene using a POSS-based star-shaped polymer for cancer therapy.

In this work, a star-shaped polymer consisting of a cationic poly[2-(dimethylamino) ethyl methacrylate] (PDMAEMA) shell and a zwitterionic poly[N-(3-(methacryloylamino) propyl)-N,N-dimethyl-N-(3-sulfo...

Ruthenium(II) polypyridyl complexes as mitochondria-targeted two-photon photodynamic anticancer agents.

Clinical acceptance of photodynamic therapy is currently hindered by poor depth efficacy and inefficient activation of the cell death machinery in cancer cells during treatment. To address these issue...

Vascularization of hollow channel-modified porous silk scaffolds with endothelial cells for tissue regeneration.

Despite the promise for stem cell-based tissue engineering for regenerative therapy, slow and insufficient vascularization of large tissue constructs negatively impacts the survival and function of th...

Tumor-specific delivery of BSH-3R for boron neutron capture therapy and positron emission tomography imaging in a mouse brain tumor model.

Glioblastoma, a malignant brain tumor with poor disease outcomes, is managed in modern medicine by multimodality therapy. Boron neutron capture therapy (BNCT) is an encouraging treatment under clinica...

News Articles [5320 Associated News Articles listed on BioPortfolio]

ASCO 2015: Adding chemotherapy to initial therapy extends lives of men with advanced, hormone-naïve prostate cancer

The UK-led trial STAMPEDE found that adding docetaxel chemotherapy to standard hormone therapy markedly improves survival for men with newly diagnosed advanced prostate cancer not previously treated w...

WHO to Fight Resistance to Antibiotic Resistance

Resistance to antibiotics and other antimicrobials is growing worldwide, and is threatening modern methods to treat and prevent disease. In the U.S. alone, the resistance accounts for an estimated 2 m...

Sanofi licenses cardiovascular therapy in South Korea

Phase III drug comes from Swedish company NeuroVive

ASCO 2015: Augmenting standard therapies increases cure rates for high-risk wilms tumour

Two phase III Children’s Oncology Group studies found that augmenting therapy with additional drugs improves outcomes for children with a high-risk form of Wilms tumour. These patients have a speci...

Ice Bucket Challenge Advances Antibody Toward Clinical Trial for ALS

The ALS Therapy Development Institute, via its wholly owned subsidiary, Anelixis Therapeutics, is directing $1.5 million toward the development of a potential treatment for ALS. Cambridge, MA (PRWEB) ...

ASCO 2015: Adding elotuzumab significantly reduces risk of progression for relapsed multiple myeloma

Interim results of a phase III trial suggest an innovative immune-based therapy may offer a new option for patients with relapsed multiple myeloma. The new monoclonal antibody elotuzumab, added to st...

Boehringer bags FDA approval for Spiriva-based combo

Stiolto given the thumbs up as a once-daily maintenance therapy for COPD

Sophiris Bio begins dosing in Phase IIa proof of concept prostate cancer trial of PRX302

Sophiris Bio has dosed first patients in a single-center, open-label Phase IIa proof of concept trial of PRX302, a clinical-stage, targeted therapy, as a treatment for localized low to intermediate ri...

CERAMENT™|G Shown To Increase Bone Formation And Decrease Infection

Pivotal Rat Study Presented at 2015 Orthopedic Research Society Annual Meeting   LUND, Sweden, May 27, 2015 /PRNewswire/ -- BONESUPPORT, an emerging leader in injectable bone substit...

Infectious Disease Experts, Scientists and Clinicians Join Forces on SHARE ID™ to Accelerate the Battle Against Antibiotic-resistant Infections

NEW YORK, May 27, 2015 /PRNewswire/-- Actavis plc (NYSE: ACT), a leading global specialty pharmaceutical company committed to infectious disease treatment innovation, today announced the creation of S...

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Companies [304 Associated Companies listed on BioPortfolio]

EO2 Concepts

EO2 Concepts is a privately held, advanced wound care technology company and the developer of a progressive FDA-cleared Class II medical device that provides therapy to difficult-...

AOBiome

AOBiome LLC is developing a transformative, new class of products based on Ammonia Oxidizing Bacteria (AOB) to improve skin health and prevent or treat skin and inflammatory disea...

NovaBay Pharmaceuticals, Inc. and Phoenix Eye Care

NovaBay Pharmaceuticals is a biopharmaceutical company focusing on commercializing and developing its non-antibiotic anti-infective products to address the unmet therapeutic needs...

Radiant Pain Relief Centres

Radiant Pain Relief Centres are progressive, patient-centric care facilities that are effectively resolving the epidemic of chronic pain, a $600B healthcare and productivity cost ...

TriggerPoint Performance Therapy

TriggerPoint™ Performance Therapy, a division of Implus Corporation, is a brand that empowers people to move better. Our innovative products are supported by simple instructi...

PEP-Therapy

www.pep-therapy.com

4D Molecular Therapeutics

4DMT is a global leader in gene therapy product research & development. 4DMT and our partners are using scientific innovation to unlock the full potential of gene therapy for pati...

NovaBay Pharmaceuticals Inc.

NovaBay Pharmaceuticals is a biopharmaceutical company focusing commercializing and developing its non-antibiotic anti-infective products to address the unmet therapeutic needs of...

KEW Group Inc.

KEW Group Inc. (KEW) is revolutionizing cancer care by empowering oncologists with access to genomic insights to design optimal, individualized treatment approaches for patients. ...

Radiant Health Management Corp

Radiant Pain Relief Centres are progressive, patient-centric care facilities that are effectively resolving the epidemic of chronic pain, a $600B healthcare and productivity cost ...

Clinical Trials [1177 Associated Clinical Trials listed on BioPortfolio]

A Study of Individualized Stereotactic Body Radiation Therapy (SBRT) for Intrahepatic Cancer

This is a Phase II trial to characterize the safety and efficacy of individualized stereotactic body radiation therapy (SRBT) for patients who have had previous liver treatment or who have...

Tinnitus Retraining Therapy Trial

The primary purpose of the Tinnitus Retraining Therapy Trial (TRTT) is to assess the efficacy of tinnitus retraining therapy (TRT) as a treatment for severe debilitating tinnitus. TRT is a...

Ampicillin for DYT-1 Dystonia Motor Symptoms

The purpose of this study is to evaluate if the antibiotic Ampicillin is safe and tolerated in patients that have generalized dystonia caused by the DYT-1 gene mutation, as compared to pat...

Suture Contamination Rate in Adjustable Suture Strabismus Surgery

1. To establish the culture positivity rate in adjustable suture strabismus surgery 2. To identify bacterial species and antibiotic susceptibility patterns of microorganisms cultur...

Personalized Adaptive Radiation Therapy With Individualized Systemic Targeted Therapy (PARTIST) for Locally Advanced, Non-small Cell Lung Cancer With Genomic Driver Mutations

Hypotheses: Short-term - Targeted therapy with erlotinib or crizotinib plus PART (Personalized Adaptive Radiation Therapy) will be safe and will yield favorable outcomes in patients with ...

MARIGOLD Study: A Study of RO4917523 Versus Placebo as Adjunctive Therapy in Patients With Major Depressive Disorder and an Inadequate Response to Ongoing Antidepressant Therapy

This randomized, double-blind, placebo-controlled, parallel group study will evaluate the safety and efficacy of RO4917523 as adjunctive therapy in patients with major depressive disorder ...

Study of Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy in Patients With Stage III Non-small Cell Lung Cancer

This randomized phase II trial studies how well positron emission tomography (PET)/computed tomography (CT)-guided radiation therapy works compared to standard radiation therapy in treatin...

Stepped Care for Young Children After Trauma

The aim of this R34 study is to develop and test the feasibility of a Stepped Care intervention for young children with Posttraumatic Stress Disorder (PTSD). Phase I will focus on developi...

Cognitive Behavior Therapy for Insomnia Delivered by a Therapist or on the Internet

Background: Insomnia is a highly prevalent and disabling disorder where Cognitive Behavior Therapy for Insomnia (CBT-I) is established as the best available treatment. Still, only a neglig...

Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy

This phase I trial studies the side effects of vaccine therapy and pembrolizumab in treating patients with solid tumors that have spread to other places in the body and usually cannot be c...

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Medical and Biotech [MESH] Definitions

A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.

Preliminary cancer therapy (chemotherapy, radiation therapy, hormone/endocrine therapy, immunotherapy, hyperthermia, etc.) that precedes a necessary second modality of treatment.

The presence of fungi circulating in the blood. Opportunistic fungal sepsis is seen most often in immunosuppressed patients with severe neutropenia or in postoperative patients with intravenous catheters and usually follows prolonged antibiotic therapy.

A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.

A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.

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