Antibiotic therapy - Biotech, Pharma and Life Science Channel

15:48 EDT 25th April 2015 | BioPortfolio

PubMed Articles [10227 Associated PubMed Articles listed on BioPortfolio]

Occurrence of tetracycline-resistant fecal coliforms and their resistance genes in an urban river impacted by municipal wastewater treatment plant discharges.

Antibiotic resistance of fecal coliforms in an urban river poses great threats to both human health and the environment. To investigate the occurrence and distribution of antibiotic resistant bacteria...

Resistance and virulence factors of Escherichia coli isolated from chicken.

Chicken meat has become an important part of the human diet and besides contamination by pathogenic Escherichia coli there is a risk of antibiotic resistance spreading via the food chain. The purpose ...

O(6)-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma.

CpG methylation in the O(6)-methylguanine-DNA methyltransferase (MGMT) promoter is associated with better outcome following alkylating agent chemotherapy in glioblastoma (GBM) and anaplastic glioma (A...

Growth hormone and early treatment.

Growth hormone (GH) treatment is approved by the US Food and Drug Administration (FDA) not only for GH deficiency (GHD) but also for other childhood growth disorders with growth failure and/or short s...

Denture-frame modifications in class III patients treated with rapid palatal expansion and facemask: a prospective controlled studys.

The aim of this prospective controlled investigation was to analyze the short-term cephalometric treatment outcomes, according to the denture frame analysis proposed by Sato, of rapid palatal expansio...

Extrapulmonary tuberculosis.

Up to 25% of tuberculosis cases present extrapulmonary involvement. This is produced by haematogenous and lymphatic spread of the M. tuberculosis bacillus to other organs. The most common locations ar...

Photodynamic therapy: a review of applications in neurooncology and neuropathology.

Improved sample treatment for the determination of 17 strong sorbed quinolone antibiotics from compost by ultra high performance liquid chromatography tandem mass spectrometry.

The use of compost from sewage sludge for agricultural application is nowadays increasing, since composting is recognized as one of the most important recycling options for this material, being a sour...

Clinical approaches to treat peri-implant mucositis and peri-implantitis.

Therapies proposed for the treatment of peri-implant diseases are primarily based on the evidence available from treating periodontitis. The primary objective is elimination of the biofilm from the im...

Clinical concepts for regenerative therapy in furcations.

Furcation involvements present one of the greatest challenges in periodontal therapy because furcation-involved molar teeth respond less favorably to conventional periodontal therapy compared with non...

News Articles [5152 Associated News Articles listed on BioPortfolio]

Merck Announces Presentation of Phase 2 Clinical Trial Results of Investigational Chronic Hepatitis C Therapy Grazoprevir/Elbasvir at the International Liver CongressTM 2015

Dateline City: VIENNA Results of C-SALVAGE Study Showed High Sustained Virologic Response Rates i...

Growing Antibiotic Shortages Threaten Patient Care

A disturbing new report shows that shortages of many important antibiotics have been worsening since 2007. Antibiotics accounted for 15% of all drug shortages from 2001-13, affecting 148 anti-infectiv...

Some Progestins May Hike Cancer; Some Estrogens May Ward it Off

A recent analysis of  long-term after-effects of a specific hormone replacement therapy (HRT)—non-physiologic hormones created by Wyeth—finds that a pattern observed while women took the drugs du...

AZ and MedImmune get exclusive rights from Innate

AstraZeneca PLC and its biologics division MedImmune LLC licensed exclusive global rights to develop and sell a cancer therapy combining their MEDI4736 with Innate Pharma SA’s IPH2201. AZ also gets ...

Opdivo Set To Be First PD-1 Inhibitor In EU After CHMP’s April Drug Reviews

Europe’s Committee for Medicinal Products for Human Use recommended Bristol-Myers Squibb’s PD-1 inhibitor Opdivo for marketing approval for melanoma and also recommended Vanda’s sleep disorder t...

1Q preview: Bayer, BMS, Celgene, GSK, Merck & Co, Pfizer and Sanofi

The first batch of big pharma/big biotech 1Q results has now been released, and the second wave is due in the week beginning 27 April. Among those that have reported, Biogen revealed lower than expect...

RNA Ebola Drug Clears Animal Study

The short interfering RNA-based therapy TKM-Ebola protects monkeys from the viral strain still circulating in West Africa.

Ibrance®

Class: Biological Therapy Generic Name: Palbociclib Trade Name: Ibrance® For which conditions is this drug approved? Ibrance is approved in combination with the medicine Femara® (letrozole) for the ...

Palbociclib

Class: Biological Therapy Generic Name: Palbociclib Trade Name: Ibrance® For which conditions is this drug approved? Ibrance is approved in combination with the medicine Femara® (letrozole) for the ...

Opdivo®

Class: Biological Therapy Generic Name: Nivolumab Trade Name: Opdivo® For which conditions is this drug approved? Opdivo is approved to treat melanoma that: a) can’t be removed by surgery; or b) me...

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Companies [297 Associated Companies listed on BioPortfolio]

NovaBay Pharmaceuticals Inc.

NovaBay Pharmaceuticals is a biopharmaceutical company focusing commercializing and developing its non-antibiotic anti-infective products to address the unmet therapeutic needs of...

KEW Group Inc.

KEW Group Inc. (KEW) is revolutionizing cancer care by empowering oncologists with access to genomic insights to design optimal, individualized treatment approaches for patients. ...

Radiant Health Management Corp

Radiant Pain Relief Centres are progressive, patient-centric care facilities that are effectively resolving the epidemic of chronic pain, a $600B healthcare and productivity cost ...

Emmaus Life Sciences, Inc.

Emmaus Life Sciences is dedicated to the discovery, development and commercialization of innovative treatments and therapies for rare diseases. The Company’s research on sick...

Newron Pharmaceuticals S.p.A.

Newron (SIX: NWRN) is a biopharmaceutical company focused on the development of novel therapies for patients with diseases of the central nervous system (CNS) and pain. The Compan...

BURGERFI

BURGERFI is one of the fastest growing restaurant franchises in the U.S. With 68 operating locations nationally, and 100 projected by year-end 2015, BURGERFI is known for its fres...

Semma Therapeutics

Semma Therapeutics was founded to develop transformative therapies for Type 1 diabetes patients. Recent work in the laboratory of Professor Douglas Melton led to the discovery of ...

InterVene Inc.

InterVene Inc. has developed the first non-implantable, catheter-based, vein valve creation therapy. The product is designed to treat chronic venous insufficiency (CVI) in the dee...

Scioderm, Inc.

Scioderm is a privately held, clinical-stage biopharmaceutical company focused on developing innovative therapies to address diseases with high need, including rare diseases. The ...

Rational Therapeutics, Inc

Who are we?Rational Therapeutics, Inc. (RTI) is a free-standing research laboratory located in Long Beach, CA. Founded in 1993 by Dr. Robert Nagourney, a prominent hematologist/oncologist, Rational Th...

Clinical Trials [1156 Associated Clinical Trials listed on BioPortfolio]

Cognitive Processing Therapy Versus Its Individual Components in the Treatment of Post-Traumatic Stress Disorder and Depression in Women Who Have Been Sexually Abused

This study will evaluate the effectiveness of cognitive processing therapy versus its individual components in treating women with post-traumatic stress disorder (PTSD) and depression brou...

Novel Treatment of Emotional Dysfunction in Post Traumatic Stress Disorder (PTSD)

The objective will be to determine if adding repetitive transcranial magnetic stimulation prior to Cognitive Processing Therapy significantly enhances recovery from hyperarousal symptoms i...

Mindfulness Based Cognitive Therapy for Psychological Distress in Pregnancy

Anxiety, stress and depression are common during pregnancy and in the postpartum period. The lack of empirically supported, non-pharmaceutical interventions for psychological distress in p...

Prospective Observational Pilot-study for the Evaluation of the Nephro- an Neurotoxicity in the Anti-infectious Therapy With Inhalative Colistin Therapy for Patients With Ventilator-associated Pneumonia (VAP)

Multi-Drug resistant pathogens (MDR) are reported worldwide with increasing incidence, especially in intensive care settings. One of the drugs which are effective against MDRs, is colisti...

Using Fiducial Markers to Aid in Prostate Cancer Radiation Treatment

To effectively treat prostate cancer, doctors need an accurate view (via X-rays) of the prostate gland during radiation therapy. To help improve this view, doctors may insert gold markers...

Detection of Reductions in Cystic Fibrosis Airway Inflammation While Using Aztreonam Lysine Solution

In cystic fibrosis, there is a critical need for better predictors of treatment response. The investigators have identified a panel of white blood cell biomarkers which can be directly mea...

Comparison of the Efficacy and Mechanisms for MBCT and CT for Multiple Sclerosis (MS) Chronic Pain

Chronic pain is a pervasive, serious problem for many individuals with multiple sclerosis (MS) that is typically inadequately treated by medications alone. There is a critical need to deve...

The Effect of Spa Treatment on Chronic Obstructive Pulmonary Disease

The primary objective of this study is to measure and compare the number of exacerbations (moderate or severe) between the two groups of randomized patients with and without thermal treatm...

IMPACT 2: Randomized Study Evaluating Molecular Profiling and Targeted Agents in Metastatic Cancer

The goal of this research study is to compare the effects of treatment based on molecular profiling to those of the standard-of-care. Treatment Assignment: From a tumor biopsy, a m...

Preoperative Antibiotic PNL Study

Percutaneous nephrolithotomy (PCNL) is a surgical procedure that is standard of care for the removal of large kidney stones. PCNL involves removal of the stone(s) from the kidney through a...

Medical and Biotech [MESH] Definitions

A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.

Preliminary cancer therapy (chemotherapy, radiation therapy, hormone/endocrine therapy, immunotherapy, hyperthermia, etc.) that precedes a necessary second modality of treatment.

The presence of fungi circulating in the blood. Opportunistic fungal sepsis is seen most often in immunosuppressed patients with severe neutropenia or in postoperative patients with intravenous catheters and usually follows prolonged antibiotic therapy.

A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.

A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.

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