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Arteriosclerosis - Biotech, Pharma and Life Science Channel

08:25 EDT 21st May 2013 | BioPortfolio

PubMed Articles [ 153 Associated PubMed Articles listed on BioPortfolio]

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Reduced carotid intima-media thickness in systemic lupus erythematosus patients treated with cyclosporine A.

BACKGROUND: Patients with systemic lupus erythematosus (SLE) are at risk of atherosclerosis. An increased carotid intima-media thickness (IMT) is considered to be a marker of early atherosclerosis. OB...

Analysis of clinical state for arteriosclerosis obliterans in lower extremity of diabetic patients on peritoneal dialysis.

OBJECTIVE:To investigate the prevalence of arteriosclerosis obliterans in lower extremity and its influence factors in diabetic patients on peritoneal dialysis. Method: In this single center cross-sec...

Relationship between Arteriosclerosis Obliterans and the Ratio of Serum Eicosapentaenoic Acid to Arachidonic Acid.

Purpose: A low ratio of serum eicosapentaenoic acid to arachidonic acid (EPA/AA) has been associated with coronary artery disease. We retrospectively examined serum concentrations of polyunsaturated f...

APC resistance due to Factor V Leiden is not related to baseline inflammatory mediators or survival up to 10 years in patients with critical limb ischemia.

To prospectively evaluate the potential influence of resistance to activated protein C (APC-resistance) on the initial inflammatory response, amputation rate and survival during 10 years of follow-up...

Anticoagulant properties of the anti-inflammatory cytokine IL-10 in a factor Xa-activated human monocyte model.

Background: Monocytes and factor Xa (FXa) are procoagulant agents implicated in the physio-pathological processes of atherosclerosis and thrombosis. Objective: we evaluated the anticoagulant effect of...

Relationship Between Myocardial Bridging and Coronary Arteriosclerosis.

The objective of the study was to explore the prevalence and characteristics of myocardial bridging in patients who underwent coronary angiography and to also evaluate the correlation between bridged...

Vascular Smooth Muscle Cell Apoptosis Promotes Transplant Arteriosclerosis Through Inducing the Production of SDF-1α.

Transplant arteriosclerosis is a leading cause of late allograft loss. Medial smooth muscle cell (SMC) apoptosis is considered to be an important event in transplant arteriosclerosis. However, the pre...

News Articles [ 38 Associated News Articles listed on BioPortfolio]

Vehicle Emissions Have An Effect On Cholesterol

Michael Harper for redOrbit.com – Your Universe Online Emissions from car and truck exhaust have already been proven to have negative and lasting effects on the earth’s atmosphere and our overal...

Islet Sciences Highlights Abstract at Arteriosclerosis, Thrombosis & Vascular Biology ATVB 2013

Islet Sciences, Inc., (OTC.BB: ISLT) a biotechnology company engaged in the research, development and commercialization of patented technologies for people with diabetes, announce...

Bad Cholesterol Lowered In Men On Heart-Healthy Diet, Regardless Of Weight Loss

A heart-healthy diet helped men at high risk for heart disease reduce their bad cholesterol, regardless of whether they lost weight, in a study presented at the American Heart Association's Arterioscl...

CORRECTING and REPLACING Esperion Therapeutics Presents Full Results of Phase 2 Clinical Trial Showing Its Novel Oral Therapy ETC-1002 Lowered LDL-C By Up to 43 Percent in Hypercholesterolemic Patients with Type 2 Diabetes

-- Data Presented at ATVB 2013 Scientific Sessions -- Please replace the release with the following corrected version due to multiple revisions. The corrected...

7 simple lifestyle steps may decrease risk of blood clots

Blood clots in the legs or lungs (deep vein thrombosis or pulmonary embolism) kill an American about every 5 minutes. Adopting seven simple lifestyle steps could help reduce your risk of these potenti...

Esperion Therapeutics Presents Full Results of Phase 2 Clinical Trial Showing Its Novel Oral Therapy ETC-1002 Lowered LDL-C By Up to 43 Percent in Hypercholesterolemic Patients with Type 2 Diabetes

-- Data Presented at ATVB 2013 Scientific Sessions -- Esperion Therapeutics, Inc., a privately-held clinical-stage biopharmaceutical company focused on developing and commerci...

Seven simple lifestyle steps may decrease risk of blood clots

Blood clots in the legs or lungs (deep vein thrombosis or pulmonary embolism) kill an American about every 5 minutes. Adopting seven simple lifestyle steps could help reduce your risk of these potenti...

Heart-healthy diet helps men lower bad cholesterol, regardless of weight loss

A heart-healthy diet helped men at high risk for heart disease reduce their bad cholesterol, regardless of whether they lost weight, in a study presented at the American Heart Association's Arterioscl...

Diet, 'anti-aging' supplements may help reverse blood vessel abnormality

A diet low in grains, beans and certain vegetables—combined with "anti-aging" supplements—improved blood vessel function, in a study presented at the American Heart Association's Arteriosclerosis,...

Pivotal Therapeutics to present "top line" results from Vascazan clinical study at American Heart Association conference

Pivotal Therapeutics (OTCQX:PVTTF) (CNSX:PVO), a pharmaceutical company focused on Omega-3 therapies for cardiovascular disease, says it will be presenting its "top line" results from a recent clinic...

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Clinical Trials [ 50 Associated Clinical Trials listed on BioPortfolio]

Evaluation of Myocardial Viability by Means of Low-Dose Dobutamine Gated SPECT (the DOGS Study)

Viability assessment remains a clinical challenge in patient with coronary artery disease and left ventricular dysfunction. Several imaging modalities are available for evaluating myocardi...

Influence of Sirolimus and MMF on Vascular Function and Markers of Cellular Function in Renal Transplant Recipients

Chronic transplant nephropathy and cardiovascular death are the main reasons for loss of transplanted organs after kidney transplantation. Vascular changes, induced by hypertension and/or...

Dietary Nitrate and Nitrite to Increase Nitric Oxide in Patients With Coronary Artery Disease

This study will determine whether dietary nitrates and nitrites can produce nitric oxide in the body and dilate blood vessels in patients with coronary artery disease. Nitric oxide is nor...

Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA)

RATIONALE: - Atherothrombosis is a progressive and generalized vascular disease resulting in events leading to myocardial infarction (heart attack), stroke, and vascular death....

High-Density Lipoprotein (HDL) Treatment Study

A low level of plasma high-density lipoprotein (HDL) cholesterol, "the good cholesterol", is the most common lipid abnormality observed in patients with a premature atherosclerotic cardiov...

Autologous Bone Marrow Stem Cell Transplantation for Critical, Limb-threatening Ischemia

Critical limb ischemia is a condition where the blood circulation in the limbs, in most cases the legs, is decreased so that pain and non healing wounds ensue. Mostly, this is a sequel of...

Culturally-Tailored Approach to Improve Medication Use in Patients With Heart Attacks

Our research aims to improve the use of medicines known to prevent recurrent heart attacks. In particular, we know that statin treatment is useful after heart attacks, but many patients do...

PIoglitazone for PrEvention of Restenosis in Diabetic Patients

Restenosis requiring reintervention is still a limitation of percutaneous coronary angioplasty. Despite the use of Drug eluting stent (DES), the rate of restenosis remains 7% to 16% in dia...

YUKON Choice Versus TAXUS Liberté in Diabetes Mellitus

Revascularisation procedures such as percutaneous coronary intervention are associated with overall worse outcomes in patients with diabetes mellitus. Implantation of coronary stents is as...

The Efficacy and Cost-Effectiveness of Behavioral Counseling for Exercise in Men and Women Following Acute Myocardial Infarction (AMI) and Percutaneous Coronary Intervention (PCI)

Purpose: The purpose of this project is to determine how effective the telephone-based counseling program is at helping patients with heart disease become more physically active. Hypothes...

Medical and Biotech [MESH] Definitions

Ticlopidine

Ticlopidine is an effective inhibitor of platelet aggregation. The drug has been found to significantly reduce infarction size in acute myocardial infarcts and is an effective antithrombotic agent in arteriovenous fistulas, aorto-coronary bypass grafts, ischemic heart disease, venous thrombosis, and arteriosclerosis.

Intracranial Hemorrhage, Hypertensive

Bleeding within the SKULL that is caused by systemic HYPERTENSION, usually in association with INTRACRANIAL ARTERIOSCLEROSIS. Hypertensive hemorrhages are most frequent in the BASAL GANGLIA; CEREBELLUM; PONS; and THALAMUS; but may also involve the CEREBRAL CORTEX, subcortical white matter, and other brain structures.

Spinal Cord Ischemia

Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.

Arteriosclerosis

Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.

Arteriosclerosis Obliterans

Common occlusive arterial disease which is caused by ATHEROSCLEROSIS. It is characterized by lesions in the innermost layer (ARTERIAL INTIMA) of arteries including the AORTA and its branches to the extremities. Risk factors include smoking, HYPERLIPIDEMIA, and HYPERTENSION.

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