Aspirin - Biotech, Pharma and Life Science Channel
PubMed Articles
The direct factor Xa inhibitor apixaban (Eliquis(®)) has predictable pharmacodynamics and pharmacokinetics and does not require routine anticoagulation monitoring. This article reviews the efficacy a...
Optimizing the Use of Aspirin for Cardiovascular Prevention.
This article describes the mechanism of action, pharmacokinetics, and pharmacodynamics of aspirin at doses used for cardiovascular prevention and provides specific management recommendations for optim...
PURPOSE: Results of the association between non-steroidal anti-inflammatory drugs (NSAIDs) and melanoma risk have been inconsistent. We performed a meta-analysis of relevant studies to investigate the...
Background Cytochrome P450 2C19 (CYP2C19) loss-of-function polymorphisms are more common in Asian populations and have been associated with diminished antiplatelet response to clopidogrel. In this era...
INTRODUCTION: To evaluate the safety and efficacy of Thulium VapoEnucleation of the prostate (ThuVEP) for patients on oral anticoagulants (OA) with symptomatic benign prostatic obstruction (BPO). METH...
Thienopyridine efficacy and cigarette smoking status.
Dual antiplatelet therapy with aspirin and a P2Y12 receptor blocker is an established regimen to reduce the risk of ischemic event occurrence in patients with high-risk cardiovascular (CV) disease. Ci...
From the earliest experiences with carotid artery stenting (CAS) presumptive high risk features have included thrombus-containing lesions, heavily calcified lesions, very tortuous vessels, and near oc...
The National Institute for Health and Clinical Excellence (NICE) invited the manufacturer of dabigatran etexilate (Boehringer Ingelheim Ltd, UK) to submit evidence for the clinical and cost-effectiven...
Monitoring of the heparinization in the rabbit animal model during endovascular interventions.
INTRODUCTION: The purpose of this study was to monitor and to optimize heparinization during endovascular procedures in the New Zealand White Rabbit (NZWR) model. METHODS: Right common carotid artery...
The fresh leaves of Murraya koenigii are often added to various dishes in Asian countries due to the delicious taste and flavour that they impart. In the present study, the effect of the total alkaloi...
News Articles
Study: Pain Killer Use Increases Hearing Loss Risk in Women
Taking pain drugs such as ibuprofen or acetaminophen (paracetamol) twice or more weekly increases the risk of hearing loss, a study has found. Researchers have found some commonly used painkillers...
Aspirin not always best treatment for many individuals
(Medical Xpress)—An aspirin a day may not always keep heart disease away, say two University of Florida cardiologists. But a new algorithm they have developed outlines factors physicians should weig...
Adaptrin®, a scientifically proven, all-natural herbal supplement drawing from traditional Tibetan medicine announced today, after its re-release this month, that it uses its 21 different herbs a...
An Aspirin a Day May Take Oneâs Hearing Away
Sturgeon Bay, WI (PRWEB) May 14, 2013 Sturgeon Bay, Wisconsin Chiropractor and Naturopath, Dr. J G Moellendorf, DC, ND, LCP notes that while aspirin has been known for decades to cause ringing...
An Aspirin a Day May Take One’s Hearing Away
Aspirin, ibuprofen, and acetaminophen are the most commonly used drugs for pain control. Dr. J G Moellendorf, DC, ND, LCP discusses recent research from the audiology profession about increased hearin...
Breast Cancer Spread May Be Reduced By Aspirin
Preliminary studies indicate aspirin may reduce the spread of breast cancer.
What Should You Tell Your Patients About Aspirin?
Aspirin has been linked to macular degeneration. When patients ask, what advice should you give about aspirin use? Medscape Ophthalmology
Review for clinicians on optimal utilization of aspirin to treat, prevent heart attacks published
Charles H. Hennekens, M.D., Dr.P.H., the first Sir Richard Doll professor and senior academic advisor to the dean in the Charles E. Schmidt College of Medicine at Florida Atlantic University published...
POZEN Reports First Quarter 2013 Results
NDA for PA32540/PA8140 Submitted to FDA in Late March POZEN Inc. (NASDAQ: POZN), a pharmaceutical company committed to transforming medicine that transforms lives, today...
A commentary and review provides clinicians with the optimal utilization of aspirin to treat and prevent heart attacks, and advice on aspirin in the prevention of colorectal and other cancers.
Events
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Companies
Corgenix is a leader in the development and manufacturing of specialized diagnostic kits for immunology disorders, vascular diseases and bone and joint disorders, including the wo...
UrgentRx provides over-the-counter medications in an innovative fast-acting powder format, available in convenient, single-dose, credit card-sized packets for easier portability and accessibility. Ini...
Corgenix is a leader in the development and manufacturing of specialized diagnostic kits for immunology disorders, vascular diseases and bone and joint disorders, including the world's only non-blood-...
Clinical Trials
Left Atrial Appendage Occlusion Study II
A pilot, multicentre randomized controlled study of surgical left atrial occlusion (LAA) in 50 patients with atrial fibrillation/flutter undergoing cardiac surgery requiring cardiopulmonar...
We would like to see if aspirin could block niacin-induced flushing by analyzing blood and urine after taking aspirin. Phase I: 5 days of 81 mg aspirin/placebo followed by 600 mg Niacin,...
Mediators of Abnormal Reproductive Function in Obesity (MARO)
The study is seeking to understand how being overweight and obese makes women less fertile. The studies the investigators have done so far indicate that there is a hormone or other substan...
Efficacy and Safety Study of Cilostazol to Prevent Reoccurrence of Stroke
The study design is subject to relevant SFDA regulations about clinical trials. This indication was approved in Japan in 2003. From the end of May 2004 to the end of Dec. 2004, 720 patien...
A Comparison of Safety and Treatment in Subjects With Osteoarthritis Taking Low Dose Aspirin
The objective of this study is to compare the gastroduodenal ulceration rate, and gastrointestinal (GI) complication rate and non-steroidal anti-inflammatory drug (NSAID)-associated dyspep...
Renal and Systemic Effects of NCX4016 in Patients With Type 2 Diabetes and Early Nephropathy
Aspirin is commonly used for treatment of painful and inflammatory diseases and in the prevention of the cardiovascular disease. A major drawback of aspirin treatment is the well recognize...
Platelets Induced Vasodilation, in Vitro and in Vivo Study
The aim of the study is to show the implication of platelets in vasodilation using in vivo and in vitro analysis and to compare the effects of placebo, aspirin and Clopidogrel in this inte...
Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis II
This study will recruit 480 acute stroke patients with symptomatic intracranial stenosis (M1 segment of Middle cerebral artery (MCA) or basilar artery). They will be randomly assigned int...
Sarpogrelate (MCI-9042) is an antiplatelet drug that decreases 5-hydroxytryptamine (5-HT) levels in platelets via a blockade of 5-HT2 receptors; it has been used in atherosclerotic periphe...
Cardiovascular Disease (CVD) Risk and Prevention in Early Glucose Intolerance
The purpose of this study is to determine whether cardiovascular disease (CVD) risk markers, β-cell function, and insulin sensitivity can be improved by targeting mechanisms of both diabe...
Videos
seka aleksic - Aspirin
http://www.pennergame.de/change_please/5777674/ Aspirin.
Medical and Biotech [MESH] Definitions
Asthma, Aspirin-induced
Asthmatic adverse reaction (e.g., BRONCHOCONSTRICTION) to conventional NSAIDS including aspirin use.
Sodium Salicylate
A non-steroidal anti-inflammatory agent that is less effective than equal doses of ASPIRIN in relieving pain and reducing fever. However, individuals who are hypersensitive to ASPIRIN may tolerate sodium salicylate. In general, this salicylate produces the same adverse reactions as ASPIRIN, but there is less occult gastrointestinal bleeding. (From AMA Drug Evaluations Annual, 1992, p120)
Aspirin
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Diflunisal
A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.
Fenoprofen
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to ASPIRIN, but causes less gastrointestinal bleeding.
