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Atrial Fibrillation and WolffParkinsonWhite Syndrome WPW - Biotech, Pharma and Life Science Channel

09:03 EDT 6th May 2016 | BioPortfolio

PubMed Articles [8733 Associated PubMed Articles listed on BioPortfolio]

Compartment Syndrome in Children: Diagnosis and Management.

Compartment syndrome (CS) can present differently in children than in adults. Increased need for analgesics is the first sign of evolving CS in children. Children with supracondylar humeral fractures,...

(177)Lu-labelled macrocyclic bisphosphonates for targeting bone metastasis in cancer treatment.

Metastatic bone lesion is a common syndrome of many cancer diseases in an advanced state. The major symptom is severe pain, spinal cord compression, and pathological fracture, associated with an obvio...

Genetics of irritable bowel syndrome.

Irritable bowel syndrome (IBS) is a common condition with a complex and largely unknown etiology. There is no cure, and treatment options are mainly directed to the amelioration of symptoms. IBS cause...

Multiple organ dysfunction syndrome in critically ill children: clinical value of two lists of diagnostic criteria.

Two sets of diagnostic criteria of paediatric multiple organ dysfunction syndrome (MODS) were published by Proulx in 1996 and by Goldstein in 2005. We hypothesized that this changes the epidemiology o...

Time Lags between Exanthematous Illness Attributed to Zika Virus, Guillain-Barré Syndrome, and Microcephaly, Salvador, Brazil.

Zika virus infection emerged as a public health emergency after increasing evidence for its association with neurologic disorders and congenital malformations. In Salvador, Brazil, outbreaks of acute ...

Different Patterns of Correlation between Grey and White Matter Integrity Account for Behavioral and Psychological Symptoms in Alzheimer's Disease.

Behavioral disorders and psychological symptoms (BPSD) in Alzheimer's disease (AD) are known to correlate with grey matter (GM) atrophy and, as shown recently, also with white matter (WM) damage. WM d...

Hypertension Is a Key Feature of the Metabolic Syndrome in Subjects Aging with HIV.

With widespread and effective antiretroviral therapy, the life expectancy in the HIV population has dramatically improved over the last two decades. Consequently, as patients are aging with HIV, other...

The "Studded" Rectum: Phenotypic Evidence of MYH-Associated Polyposis.

MYH-associated polyposis is a recessively inherited syndrome of colorectal cancer predisposition attributed to biallelic germline mutations in the base excision repair gene MYH. Clinically it overlaps...

Transverse Perineal Support: A Novel Surgical Treatment for Perineal Descent in Patients With Obstructed Defecation Syndrome.

We hypothesized that pathological perineal descent may be responsible for the failure of operations for obstructed defecation syndrome and that correcting excessive perineal descent may improve the ou...

Tenofovir disoproxil fumarate-induced Fanconi's syndrome during HIV postexposure prophylaxis.

News Articles [3933 Associated News Articles listed on BioPortfolio]

Atrial fibrillation patients on warfarin have increased risk of dementia

Patients with atrial fibrillation (AF) being treated with warfarin have higher rates of dementia compared with those taking the drug for other conditions, research shows.

Creative Agency Baldwin & Obenauf, Inc. (BNO), the NJ Center for Tourette Syndrome (NJCTS), and Soccer Star Tim Howard Expand The GreaTS Global Tourette Syndrome Awareness Platform

SOMERVILLE, N.J., May 6, 2016 /PRNewswire/ -- Launching today, StandWithTheGreaTS.org is a digital hub for The GreaTS global Tourette Syndrome movement that educates, informs, and issues a powerful ca...

Delayed diagnosis, barriers to care increase morbidity in children with Cushing’s syndrome

Hispanic and black children diagnosed with Cushing’s syndrome are more likely to present with higher cortisol measurements and larger tumor size vs. white children, according to study findings prese...

LivaNova: Miscellaneous

SonR: 35% Risk Reduction in Heart Failure Hospitalization RESPOND-CRT LANDMARK TRIAL REVEALS A REDUCED RISK IN HEART FAILURE HOSPITALIZATION WITH LIVANOVA'S EXCLUSIVE SONR SENSOR-BASED ...

Study examines whether compression stockings can prevent post-thrombotic syndrome

Deep vein thrombosis occurs when a blood clot forms in a vein, often in the deep veins of the legs, thigh or pelvis. Approximately half of people with this problem will develop post thrombotic syndrom...

Cardiome and Allergan Announce XYDALBA™ (Dalbavancin) Licensing Agreement in International Markets

NASDAQ: CRME    TSX: COM VANCOUVER, May 5, 2016 /PRNewswire/ - Cardiome Pharma Corp. (NASDAQ: CRME / TSX: COM) announced that its affiliate has signed an exclusive license agreement with ...

Successful AF ablation reduces health care costs

SAN FRANCISCO — Patients with atrial fibrillation who are event-free after catheter ablation had a 40% reduction in their health care costs, according to data presented at the Heart Rhythm Society A...

People can be trained to think in a way that protects them from PTSD

People who may be exposed to trauma can train themselves to think in a way that could protect them from PTSD symptoms, according to a study from Kings College London and Oxford University. Clini...

Widely Used Heart Drug Tied to Dementia Risk

THURSDAY, May 5, 2016 -- People with the heart rhythm disorder atrial fibrillation may have a heightened risk of developing dementia -- and the quality of their drug treatment may play a role, a new s...

White House calls FDA e-cigarettes move a 'common sense' proposal

WASHINGTON, May 5 (Reuters) - The White House called the Food and Drug Administration move on Thursday to ban the sale of e-cigarettes and cigars to anyone under age 18 and impose other regulations a ...

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Companies [150 Associated Companies listed on BioPortfolio]

XenoPort

We are a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates for the potential treatment of central nervous system (CNS) disorders. We also have a p...

LuxCath LLC

LuxCath is a leader in catheter-based, real-time, optical tissue-electrode contact assessment, lesion progression monitoring, and lesion visualization for cardiac ablation. LuxCat...

Velicept Therapeutics, Inc.

Velicept Therapeutics, Inc. is a privately held, clinical development company focused on advancing best-in-class compounds with the potential to fill unmet medical needs. Its lead...

Alexion Pharmaceuticals Inc.

Alexion is a global biopharmaceutical company focused on developing and delivering life-transforming therapies for patients with devastating and rare disorders. Alexion developed ...

Prana Biotechnology

Prana Biotechnology has developed a proprietary library of class-leading chemical compounds. This library is combined with a drug development program to explore novel therapeutics in multiple disease ...

PathMaker Neurosystems Inc.

PathMaker Neurosystems Inc. is a clinical-stage neuromodulation company founded to commercialize recent breakthrough advances in the development and clinical application of trans-...

Delaware Park

Delaware Park is a multi-level gaming facility, offering guests more than 2,300 exciting slot machines, live table games including poker, blackjack, craps and roulette, cash and t...

Cigna Corporation and WESTMED Medical Group

WESTMED Medical Group is a large multi-specialty group medical practice, with headquarters in Purchase, NY. It is staffed by a team of 318 physicians dedicated to providing coordi...

Neuropore Therapies, Inc.

Neuropore Therapies is developing novel small molecule therapeutics to treat and slow the progression of neurodegenerative disorders such as Alzheimer’s and Parkinson’s ...

Dannon Company, Inc.

The Dannon Company is America's founding national yogurt company and continually leverages its expertise to develop and market innovative cultured fresh dairy products in the Unit...

Clinical Trials [4286 Associated Clinical Trials listed on BioPortfolio]

Effect of Pendular Exercises in Parkinson's Disease

This study evaluates the effect of body suspension and tilting exercises (performed in Chordata apparatus) on the balance and mobility of subjects with Parkinson disease. Half of patients ...

Pharmacokinetic-Pharmacodynamic Interaction Between Four Different Single Doses of BIA 3-202 and a Single Dose of Levodopa/Benserazide (100/25 mg)

The purpose of this study is to investigate the tolerability, pharmacokinetic profile of BIA 3-202 and its metabolites, and the pharmacokinetic and pharmacodynamic interaction between 4 di...

Pharmacokinetic-Pharmacodynamic Interaction Between Four Different Single Doses of BIA 3-202 and a Single Dose of Levodopa/Carbidopa (100/25 mg)

The purpose of this study is to investigate the tolerability, pharmacokinetic profile of BIA 3-202 and its metabolites, and the pharmacokinetic and pharmacodynamic interaction between 4 di...

Comparison of Two Oral Appliances in the Treatment of Sleep Apnea Syndrome

Monocentric comparative group study comparing the efficacy and short-term tolerance of a propulsion type oral appliance (Herbst) with a retention type device (ORM) used in the treatment of...

Study to Investigate the Safety, Tolerability, Steady State Pharmacokinetic and Pharmacodynamic Profile of BIA 3-202

The objectives as stated in the study protocol were as follows: - To investigate the safety and tolerability of three multiple dose regimens of BIA 3-202 (50 mg twice a day, 100 m...

A Phase I Study to Investigate the Safety, Tolerability, Pharmacokinetics (Including Food Interaction), and Pharmacodynamics of Single Doses of BIA 3-202

The purpose of this study is to investigate the safety and tolerability of single oral rising doses of BIA 3-202 up to 800 mg (proposed doses 10 mg, 30 mg, 50 mg, 100 mg, 200 mg, 400 mg an...

Dementia in Parkinson Disease

The purpose of this study is to use a brain imaging method called PIB PET VAT PET to determine dementia subtypes in patients with Parkinson's disease. The ultimate goal of this project is ...

Deep Brain Stimulation (DBS) of the Nucleus Basalis of Meynert (NbM) in Patients With Parkinson's Disease

The existing DBS setting in patients with DBS of the globus pallidus interna (GPi), which aims to treat motor symptoms by a high-frequency stimulation, will be temporarily reprogramed to s...

Effect of the Kinesio Taping in Fibromyalgia.

The prevalence of the fibromyalgia is about 10-15% in the European countries. It is unclear the etiology and pathogenesis of the syndrome. Several factors such as dysfunction of the centra...

Intermittent Oral Administration vs. Semi-continuous Intra-oral Administration of Levodopa/Carbidopa in Fluctuating Parkinsonian Patients

This is a phase IIa study to assess the safety, tolerability, plasma pharmacokinetics and efficacy of intermittent oral administration of standard levodopa/carbidopa (LD/CD) vs.semi-contin...

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Medical and Biotech [MESH] Definitions

A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulse conducts to the HEART VENTRICLES via an accessory pathway located between the wall of the right or left atria and the ventricles, known as the bundle of Kent. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).

A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)

Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)

A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.

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