Atrial Fibrillation and WolffParkinsonWhite Syndrome WPW - Biotech, Pharma and Life Science Channel

20:35 EST 24th November 2014 | BioPortfolio

PubMed Articles [8284 Associated PubMed Articles listed on BioPortfolio]

Next Generation Semiconductor Based-Sequencing of a Nutrigenetics Target Gene (GPR120) and Association with Growth Rate in Italian Large White Pigs.

The GPR120 gene (also known as FFAR4 or O3FAR1) encodes for a functional omega-3 fatty acid receptor/sensor that mediates potent insulin sensitizing effects by repressing macrophage-induced tissue inf...

Novel Polymorphisms in Porcine 3'UTR of the Leptin Gene, Including a Rare Variant within Target Sequence for MIR-9 Gene in Duroc Breed, not Associated with Production Traits.

The leptin gene (LEP) is considered as a functional candidate for production traits in livestock due to its crucial role in energy homeostasis. Because polymorphisms in regulatory sequences may affect...

Chemical composition and antioxidant activity of seven cultivars of guava (Psidium guajava) fruits.

The antioxidant activity and identification of phenolic compounds of seven edible guava (Psidium guajava) cultivars that varied in colour from white to pink were examined. In the DPPH assay all four p...

Weight Loss Attitudes and Social Forces in Urban Poor Black and White Women.

To explore differences between Blacks and Whites in perceived influences on weight-related behaviors among obese urban poor women.

Retraction notice to 'Phenolic composition, antioxidant properties, and endothelial cell function of red and white cranberry fruits' Food Chem. 157 (2014) 540-552.

Immune reconstitution inflammatory syndrome mimicking progressive multifocal leucoencephalopathy in a multiple sclerosis patient treated with natalizumab: a case report and review of the literature.

Natalizumab (NTM) represents an effective drug for the treatment of relapsing-remitting multiple sclerosis (RRMS). Progressive multifocal leucoencephalopathy (PML) is a potential life-threatening comp...

Young patient presenting acute coronary syndrome.

The clinical presentation of Kawasaki disease (KD) is variable and clinical implication among adults is rarely important but coronary involvement. Here we report a young patient showing recurrent acut...

Stochastic Anomaly Detection in Eye-Tracking Data for Quantification of Motor Symptoms in Parkinson's Disease.

Two methods for distinguishing between healthy controls and patients diagnosed with Parkinson's disease by means of recorded smooth pursuit eye movements are presented and evaluated. Both methods are ...

Controversies in cardioembolic stroke.

Cardioembolic (CE) stroke mechanisms account for a significant number of ischemic strokes; however, the true burden is likely underestimated. It is critically important to identify patients with CE st...

Morbidity and mortality in young-onset type 2 diabetes in comparison to type 1 diabetes: where are we now?

Increasingly, we recognise that type 2 diabetes in youth is a disease with an aggressive time course and a significant complication risk. On the other hand, outcomes for youth with type 1 diabetes app...

News Articles [3455 Associated News Articles listed on BioPortfolio]

Marlo Thomas Receives Presidential Medal of Freedom

MEMPHIS, Tenn., Nov. 24, 2014 /PRNewswire-USNewswire/ -- Today, St. Jude Children's Research Hospital® National Outreach Director, Marlo Thomas, was presented with the Presidential Meda...

Muscle relaxant may be viable treatment for Wolfram syndrome—rare form of diabetes

A commonly prescribed muscle relaxant may be an effective treatment for a rare but devastating form of diabetes, researchers at Washington University School of Medicine in St. Louis report.

WHO is Notified of Five Cases of MERS-CoV in Saudi Arabia

Between Oct. 12 and Oct. 16, 2014, the National IHR Focal Point for the Kingdom of Saudi Arabia (KSA) notified the World Health Organization (WHO) of five additional cases of Middle East respiratory s...

Calorie-Focused Thinking When It Comes to Obesity May Mislead and Harm Public Health

New paper co-authored by Saint Luke’s Mid America Heart Institute cardiovascular research scientist provides an alternate view on obesity Kansas City, Mo. (PRWEB) November 24, 2014 Perhaps not all ...

Transition Therapeutics climbs after positive specialized study for Alzheimer's drug

Transition Therapeutics (NASDAQ:TTHI) (TSE:TTH) shares popped today after announcing the results of a specialized study of its neuropsychiatric drug candidate ELND005, which it said was safe and well-...

Karmanos Cancer Institute's Hayley Thompson, Ph.D., awarded $1.8 million grant to improve access to cancer survivor resources

DETROIT, Nov. 24, 2014 /PRNewswire-USNewswire/ -- Hayley S. Thompson, Ph. D., associate professor, Population Studies and Disparities Research Program at the Barbara Ann Karmanos Cancer Institute, and...

Teduglutide Granted Orphan Drug Designation in Japan

NPS Pharmaceuticals, Inc. (NASDAQ:NPSP), a global biopharmaceutical company pioneering and delivering therapies that transform the lives of patients with rare diseases, today anno...

San Antonio Pain Clinic, Premier Pain Consultants, Now Offering Revolutionary Spinal Cord Stimulator Implants for Back and Leg Pain

The top pain management clinics in San Antonio, Premier Pain Consultants, are now offering revolutionary spinal cord stimulator implants. The cutting edge treatment has been incredible for back and le...

MRC Technology and China’s Yabao Pharma partner to develop Parkinson’s drugs

The UK’s independent medical research charity MRC Technology and Chinese drugmaker Yabao Pharmaceutical have entered into an exclusive license agreement.

The Marcus Foundation Awards Multi-Year Grant to Team Red, White and Blue Supporting U.S. Veterans and Their Families in the Southeast

Funds Support 7,000 Team Red, White and Blue Members – and Growing – in the Southeast Region of the United States Through Physical and Social Activity Team R...

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Companies [122 Associated Companies listed on BioPortfolio]

Team Red, White and Blue

Team Red, White and Blue (Team RWB) is a registered 501(c)3 nonprofit organization with headquarters in Chicago, IL. Team RWB’s mission is to enrich the lives of Americaâ€...

Cortendo AB

Cortendo AB is a biopharmaceutical company headquartered in Göteborg, Sweden. Its stock is publicly traded on the NOTC-A-list (OTC) in Norway. Cortendo is a pioneer in the fiel...

Innocrin Pharmaceuticals, Inc.

Innocrin discovers and develops novel, best-in-class oral inhibitors of CYP17 lyase, a validated enzyme target for the treatment of castration-resistant prostate cancer. VT-464 an...

Nolan Auerbach & White

Tenax Therapeutics, Inc.

Tenax Therapeutics, Inc. (formerly Oxygen Biotherapeutics) is a specialty pharmaceutical company focused on developing and commercializing a portfolio of products for the critical...

DC Devices, Inc.

DC Devices, Inc. is dedicated to revolutionizing the treatment of heart failure with first-in-class structural heart devices. The company has developed the world’s first tran...

Lysosomal Therapeutics Inc.

Lysosomal Therapeutics Inc. (LTI) is dedicated to innovative small-molecule research and development in the field of neurodegeneration, yielding new treatment options for patie...

Clear Seas Communications

Jarden Corporation is a leading provider of a diverse range of consumer products with a portfolio of over 120 trusted, quality brands sold globally. Jarden operates in three prima...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Life Stem Genetics, Inc.

Life Stem Genetics (“LSG”) is a progressive healthcare company focused on Adult Stem Cell (ASC) healing therapies. For decades, stem cells have been utilized in the succ...

Clinical Trials [3229 Associated Clinical Trials listed on BioPortfolio]

Pasireotide Therapy in Patients With Nelson's Syndrome

Nelson's syndrome, an expanding pituitary tumour, occurs in up to 30% of adults after bilateral adrenalectomy for Cushing's disease, for which no medical treatment exists. Plasma Adrenocor...

A Screening Protocol to Assess Adults and Adolescents With Down Syndrome for Eligibility For Upcoming Study of RG1662 (Study BP27832)

This is a single visit study in which people with Down syndrome aged 12-30 will attend the clinical center to undergo assessments to evaluate their eligibility for potential enrollment in ...

Eisenmenger Syndrome in the Nordic Countries

This is a historical cohort study with retrospective collection of data comprising all Nordic patient's diagnosed with Eisenmengers syndrome in the period 1977 through 2011. The goal is to...

Satisfaction/Quality of Life With Rivaroxaban in SPAF (Stroke Prevention in Atrial Fibrillation) Indication

National, multicenter, prospective, observational, non-interventional study. The objective is to determine if the switch from Vitamin K antagonists (VKA) to Xarelto in subjects treated wit...

A Post Marketing Survey Study to Evaluate the Safety and Effectiveness of Prezista

The purpose of this study is to assess the safety data of darunavir in a natural clinical practice.

Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Int-1 or Trisomy 8 Int-2 Myelodysplastic Syndrome

The primary objectives of this study are to determine if rigosertib sodium, given orally in the form of soft gel capsules, is safe and is associated with a reduction in the number of blood...

Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure

Premature ovarian failure (POF) is known to be associated with an increased risk of ocular surface disease (dry eye), likely due to the reduction of both estrogens and androgens seen in th...

Early Treatment of Atrial Fibrillation for Stroke Prevention Trial

EAST prospectively tests the hypothesis that an early, structured rhythm control therapy based on antiarrhythmic drugs and catheter ablation can prevent atrial fibrillation (AF) related co...

Consolidation of Motor Learning of Writing Skills and Its Related Brain Activity Changes in Parkinson&Apos;s Disease

The basal ganglia play an important role in motor learning, especially during the consolidation phase of motor learning. This raises the question whether it is possible to sustain learning...

Natural History of Salivary Gland Dysfunction and Sj(SqrRoot)(Delta)Gren s Syndrome

This study will follow patients with salivary gland dysfunction to identify the long-term course of this disorder and its effects on the mouth, oral function, and overall health. Saliva is...

Medical and Biotech [MESH] Definitions

A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulse conducts to the HEART VENTRICLES via an accessory pathway located between the wall of the right or left atria and the ventricles, known as the bundle of Kent. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).

A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)

Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)

A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.

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