Atrial Fibrillation and WolffParkinsonWhite Syndrome WPW - Biotech, Pharma and Life Science Channel

15:44 EST 27th November 2014 | BioPortfolio

PubMed Articles [8284 Associated PubMed Articles listed on BioPortfolio]

Next Generation Semiconductor Based-Sequencing of a Nutrigenetics Target Gene (GPR120) and Association with Growth Rate in Italian Large White Pigs.

The GPR120 gene (also known as FFAR4 or O3FAR1) encodes for a functional omega-3 fatty acid receptor/sensor that mediates potent insulin sensitizing effects by repressing macrophage-induced tissue inf...

Novel Polymorphisms in Porcine 3'UTR of the Leptin Gene, Including a Rare Variant within Target Sequence for MIR-9 Gene in Duroc Breed, not Associated with Production Traits.

The leptin gene (LEP) is considered as a functional candidate for production traits in livestock due to its crucial role in energy homeostasis. Because polymorphisms in regulatory sequences may affect...

Chemical composition and antioxidant activity of seven cultivars of guava (Psidium guajava) fruits.

The antioxidant activity and identification of phenolic compounds of seven edible guava (Psidium guajava) cultivars that varied in colour from white to pink were examined. In the DPPH assay all four p...

Weight Loss Attitudes and Social Forces in Urban Poor Black and White Women.

To explore differences between Blacks and Whites in perceived influences on weight-related behaviors among obese urban poor women.

Retraction notice to 'Phenolic composition, antioxidant properties, and endothelial cell function of red and white cranberry fruits' Food Chem. 157 (2014) 540-552.

Immune reconstitution inflammatory syndrome mimicking progressive multifocal leucoencephalopathy in a multiple sclerosis patient treated with natalizumab: a case report and review of the literature.

Natalizumab (NTM) represents an effective drug for the treatment of relapsing-remitting multiple sclerosis (RRMS). Progressive multifocal leucoencephalopathy (PML) is a potential life-threatening comp...

Young patient presenting acute coronary syndrome.

The clinical presentation of Kawasaki disease (KD) is variable and clinical implication among adults is rarely important but coronary involvement. Here we report a young patient showing recurrent acut...

Stochastic Anomaly Detection in Eye-Tracking Data for Quantification of Motor Symptoms in Parkinson's Disease.

Two methods for distinguishing between healthy controls and patients diagnosed with Parkinson's disease by means of recorded smooth pursuit eye movements are presented and evaluated. Both methods are ...

Controversies in cardioembolic stroke.

Cardioembolic (CE) stroke mechanisms account for a significant number of ischemic strokes; however, the true burden is likely underestimated. It is critically important to identify patients with CE st...

Morbidity and mortality in young-onset type 2 diabetes in comparison to type 1 diabetes: where are we now?

Increasingly, we recognise that type 2 diabetes in youth is a disease with an aggressive time course and a significant complication risk. On the other hand, outcomes for youth with type 1 diabetes app...

News Articles [3443 Associated News Articles listed on BioPortfolio]

ItsHot.com offering 70-80% off on its Attractive Collection of Diamond Crosses

ItsHot.com, a renowned manufacturer, wholesaler, and retailer of diamond jewelry in NY, is now offering a whopping 70-80% discount on its gorgeous collection of diamond crosses, along with an attracti...

NICE's Soliris yes proves expensive drugs can make it

Soliris has been recommended in final draft guidance to treat atypical hemolytic uremic syndrome (aHUS), a condition affecting just 200 people in the UK. Despite the small patient population, NICE est...

NICE final draft guidance recommends Soliris, but saying it is “very expensive”

The UK National Institute for Health and Care Excellence (NICE) has today issued final draft guidance recommending US drugmaker Alexion Pharmaceuticals’ Soliris (eculizumab) for funding for treatin...

Needle-Free Drug Delivery Will Improve Treatments in the Global Human Growth Hormone Market: TechNavio

The Global Human Growth Hormone (HGH) Market is expected to grow at a CAGR of 4.22 percent from 2015-2019, in response to increased demand for HGH treatments, says research...

Ice and white roses

A distant memory.

Further delineation of the KBG syndrome phenotype caused by ANKRD11 aberrations

Deletion of protein tyrosine phosphatase, non-receptor type 4 (PTPN4) in twins with a Rett syndrome-like phenotype

Signature Case for iPhone 6 and 6 Plus Shipping Now from Sunrise Hitek

Sunrise Hitek introduces their new Signature Case for iPhone 6 and 6 Plus https://uuberstore.com/product/signature-iphone-6-plus. This case is shipping now in models for iPhone 6 and 6 Plus in color c...

NHS to get world’s most expensive drug

UK health watchdog NICE has recommended Alexion’s Soliris for patients with the rare disease atypical haemolytic uremic syndrome (aHUS).  Soliris (eculizumab) is the most expensive drug in the ...

GSK, NIH declare Ebola vaccine safety test a success

The Phase I victory, which was praised by the White House, means the vaccine can move into efficacy testing, which is expected to get underway in mid-January in Liberia, if all goes according to NIAID...

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Companies [122 Associated Companies listed on BioPortfolio]

Team Red, White and Blue

Team Red, White and Blue (Team RWB) is a registered 501(c)3 nonprofit organization with headquarters in Chicago, IL. Team RWB’s mission is to enrich the lives of Americaâ€...

Cortendo AB

Cortendo AB is a biopharmaceutical company headquartered in Göteborg, Sweden. Its stock is publicly traded on the NOTC-A-list (OTC) in Norway. Cortendo is a pioneer in the fiel...

Innocrin Pharmaceuticals, Inc.

Innocrin discovers and develops novel, best-in-class oral inhibitors of CYP17 lyase, a validated enzyme target for the treatment of castration-resistant prostate cancer. VT-464 an...

Nolan Auerbach & White

Tenax Therapeutics, Inc.

Tenax Therapeutics, Inc. (formerly Oxygen Biotherapeutics) is a specialty pharmaceutical company focused on developing and commercializing a portfolio of products for the critical...

DC Devices, Inc.

DC Devices, Inc. is dedicated to revolutionizing the treatment of heart failure with first-in-class structural heart devices. The company has developed the world’s first tran...

Lysosomal Therapeutics Inc.

Lysosomal Therapeutics Inc. (LTI) is dedicated to innovative small-molecule research and development in the field of neurodegeneration, yielding new treatment options for patie...

Clear Seas Communications

Jarden Corporation is a leading provider of a diverse range of consumer products with a portfolio of over 120 trusted, quality brands sold globally. Jarden operates in three prima...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Life Stem Genetics, Inc.

Life Stem Genetics (“LSG”) is a progressive healthcare company focused on Adult Stem Cell (ASC) healing therapies. For decades, stem cells have been utilized in the succ...

Clinical Trials [3232 Associated Clinical Trials listed on BioPortfolio]

Lenalidomide and Prednisone in Low and Int-1 Myelodysplastic Syndrome (MDS) Non 5q MDS

The purpose of this research is to evaluate the use of lenalidomide and prednisone in people with Myelodysplastic Syndrome (MDS). Lenalidomide is a drug that alters the immune system and ...

Safety, Pharmacokinetics, and Pharmacodynamics of NBI-98854 in Children and Adolescents With Tourette Syndrome

This is a Phase 1b, open-label, multiple-dose study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of NBI-98854 in a total of 36 pediatric subjects with Tourette syndrome ...

Apixaban for the Secondary Prevention of Thromboembolism Among Patients With the AntiphosPholipid Syndrome

ASTRO-APS is a prospective, randomized, open-label blinded endpoint pilot study among patients with a clinical diagnosis of the AntiPhospholipid Syndrome and are already taking an anticoag...

Busulfan and Etoposide Followed by Peripheral Blood Stem Cell Transplant and Low-Dose Aldesleukin in Treating Patients With Acute Myeloid Leukemia

This phase II trial studies the side effects and how well giving busulfan and etoposide followed by peripheral blood stem cell transplant (PBSCT) and low-dose aldesleukin works in treating...

Effect of Progestin-Induced Withdrawal Bleed on Ovulation Induction Cycles With Clomiphene Citrate

Women with polycystic ovary syndrome (PCOS) can suffer from infertility because they do not produce an egg each month, resulting in irregular periods. As a result, these women often need a...

Natural History and Genetic Studies of Usher Syndrome

This study will explore clinical and genetic aspects of Usher syndrome, an inherited disease causing deafness or impaired hearing, visual problems, and, in some cases, unsteadiness or bala...

Protein Synthesis in the Brain of Patients With Fragile X Syndrome

Biosynthesis of proteins is essential for growth and continued maintenance of the entire neuron including axons, dendrites, and synaptic terminals, and it is clearly one of the important b...

Trial to Assess the Effects of Vorapaxar (SCH 530348; MK-5348) in Preventing Heart Attack and Stroke in Particpants With Acute Coronary Syndrome (TRA•CER) (Study P04736)

The study is designed to determine whether vorapaxar, when added to the existing standard of care (eg, aspirin, clopidogrel) for preventing heart attack and stroke in patients with acute c...

Family Adaptation Study Following the Diagnosis of Hypoplastic Left Heart Syndrome in a Newborn

Survival for one of the most complex forms of congenital heart disease, hypoplastic left heart syndrome (HLHS), has improved dramatically. However, little is known about family stress, co...

A Study Exploring Two Strategies of Rivaroxaban (JNJ39039039; BAY-59-7939) and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention

The primary purpose of this study is to evaluate the safety for 2 different rivaroxaban treatment strategies and one Vitamin K Antagonist (VKA) treatment strategy utilizing various combina...

Medical and Biotech [MESH] Definitions

A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulse conducts to the HEART VENTRICLES via an accessory pathway located between the wall of the right or left atria and the ventricles, known as the bundle of Kent. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).

A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)

Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)

A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.

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