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Atrial Fibrillation and WolffParkinsonWhite Syndrome WPW - Biotech, Pharma and Life Science Channel

14:28 EDT 18th April 2014 | BioPortfolio

PubMed Articles [6202 Associated PubMed Articles listed on BioPortfolio]

Aspirin Desensitization: Useful Treatment for Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) in Aspirin-Exacerbated Respiratory Disease (AERD)?

Aspirin intolerance syndrome is due to disturbances in the arachidonic acid metabolism implicating both the lipoxygenase and cyclooxygenase pathways. This results in imbalances of eicosanoid, leukotri...

Good's Syndrome, CVID, and Selective Antibody Deficiency in Patients with Chronic Rhinosinusitis.

Good's syndrome and common variable immune deficiency (CVID) are associated with chronic rhinosinusitis. Good's syndrome is characterized by hypogammaglobulinemia, B-cell depletion, variable defects i...

An attractive way of egg white protein by-product use for producing of novel anti-hypertensive peptides.

The aim of this study was to (i) examine how enzymatic hydrolysis with a non-commercially available proteinase of fig-leaf gourd fruit (Cucurbita ficifolia) increased the use value of egg white protei...

Colloidal iron(III) pyrophosphate particles.

Ferric pyrophosphate is a widely used material in the area of mineral fortification but its synthesis and properties in colloidal form are largely unknown. In this article, we report on the synthesis...

Evaluation of triple stage mass spectrometry as a robust and accurate diagnostic tool for determination of free cordycepin in designer egg.

Direct determination of free cordycepin in designer egg using a highly selective mass spectrometric (MS) technique aided by a rapid and efficient dilute-and-shoot workflow would enhance their applicat...

Modified COLD-PCR for detection of minor microorganisms in wine samples during the fermentation.

The detection of low-abundant microorganism is difficult when in a sample in which a specific microorganism represents an overwhelming majority using polymerase chain reaction (PCR)-based methods. A m...

Influence of dietary pattern, physical activity, and I148M PNPLA3 on steatosis severity in at-risk adolescents.

Evidence relating dietary patterns to obesity and related disorders such as non-alcoholic fatty liver disease (NAFLD) is limited in pediatric age. Aim of this study was to analyze the association betw...

Platelet function testing in contemporary clinical and interventional practice.

Dual antiplatelet therapy with a combination of aspirin and an inhibitor of the ADP P2Y12 receptor is the recommended treatment for patients with acute coronary syndrome or who are undergoing percutan...

Management of hyponatremia in clinical hepatology practice.

The burden of liver disease continues to increase in the United States, with the epidemics of hepatitis C, alcoholic liver disease, and the coming wave of nonalcoholic fatty liver disease patients all...

Anti-epileptic drugs and hormonal treatments.

Epilepsy and the medications used in its treatment are known to affect the menstrual cycle, aspects of contraception, and bone health in women. Adolescence is an important time to review the diagnosis...

News Articles [3266 Associated News Articles listed on BioPortfolio]

Neumedicines Publishes Clinical Data Demonstrating Safety and Hematopoietic and Immune Effects of HemaMax™ (rHuIL-12), a Radiation Medical Countermeasure

Clinical data provides strong supportive evidence of the efficacy and safety of HemaMax™ for the treatment of Acute Radiation Syndrome. Pasadena, California (PRWEB) April 18, 2014 Neumedicines Inc....

Sign-Up Figures Trigger New Round Of Health Law Political Spin

President Barack Obama uses the new enrollment numbers to urge Democrats to be proud of the health law and call on Republicans to back off in their push to repeal the measure. GOP leaders, though, did...

At 8 Million Sign-Ups, Health Law Enrollment Surpasses Target

President Barack Obama hailed the latest tally of people who gained insurance as a result of the health law. News outlets also look inside this latest round of data to find out what inf...

Obama Presses Scrutiny Of 2015 Health Insurance Rates

The president made his appeal to state insurance commissioners at a meeting Thursday. Elsewhere, consumer spending related to the health law jumps, the GOP again demands to know the White House's invo...

Chronic Prostatitis Which Causes Neuroticism Must Get Localized Thermobalancing Therapy of Prostate in the First Place

Men with chronic prostatitis may develop depression and neuroticism in response to poorer treatment a recent study says. At the same time it is possible to achieve chronic prostatitis and prostate enl...

20th Parkinson's Unity Walk to Take Place on April 26 in New York City's Central Park

KINGSTON, N.J., April 18, 2014 /PRNewswire-USNewswire/ -- The Parkinson Alliance announced today that the 20th Parkinson's Unity Walk will take place on Saturday, April 26, 2014, in New York City...

Know the brain, and its axons, by the clothes they wear

(Medical Xpress)—It is widely know that the grey matter of the brain is grey because it is dense with cell bodies and capillaries. The white matter is almost entirely composed of lipid-based myelin,...

Autonomy and relationships among 'good life' goals

Young adults with Down syndrome have a strong desire to be self-sufficient by living independently and having a job, according to a study into the meaning of wellbeing among young people affected by t...

Brinks Charity Tourney a Big Win

Golf Tournament in Texas Supports The Research Down Syndrome Foundation Dallas, TX (PRWEB) April 18, 2014 Brink’s North America President Mel Parker was all smiles when a teammate sunk a 52 foot pu...

Obama: ACA hits 8m; time to 'forcefully defend'

"I don't think we should apologize for it and I don't think we should be defensive about it. I think there is a strong, good, right story to tell," President Obama said from the White House briefing r...

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Companies [110 Associated Companies listed on BioPortfolio]

Akebia Therapeutics, Inc.

Akebia Therapeutics is a discovery and development company focused on anemia and vascular disorders. Akebia’s lead program, AKB-6548, an orally bioavailable HIF-prolyl hydrox...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

EnVivo Pharmaceuticals

Mission: to discover and develop small-molecule therapeutics for disorders of the central nervous system (CNS), specifically neurodegenerative diseases, such as Alzheimer’s Disease, Parkinson’s Di...

XenoPort

We are a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates for the potential treatment of central nervous system (CNS) disorders. We also have a p...

NPS Pharmaceuticals

NPS Pharmaceuticals is engaged in the discovery, development and commercialization of therapeutic small molecules and recombinant proteins to treat bone and mineral, gastrointestinal and central nervo...

PixarBio Corporation

PixarBio Corporation is dedicated to developing new therapeutic options for Parkinson’s disease. Co-founded by Robert S. Langer from MIT’s Langer Lab and Frank Reynolds,...

My Possibilities

My Possibilities is a Plano, Texas-based non-profit, charity - 501(c)(3), for adults with disabilities (Autism, Down Syndrome, Aspergers, Prader-Willi, Head Injuries, etc.). St...

Life Stem Genetics, Inc.

Life Stem Genetics (“LSG”) is a progressive healthcare company focused on Adult Stem Cell (ASC) healing therapies. For decades, stem cells have been utilized in the succ...

Life Stem Genetics Inc.

Life Stem Genetics (“LSG”) is a progressive health care company that focuses on healing with a patient’s own “Stem Cells”. Stem Cells for years have been...

Novogen

Novogen's business is in the most pressing area facing medicine in the modern era - that of degenerative diseases and disorders. Cancer Heart disease (stroke, hypertension, coronary artery disea...

Clinical Trials [3100 Associated Clinical Trials listed on BioPortfolio]

Acute Effects of Preladenant (SCH 420814) on Dyskinesia and Parkinsonism in Levodopa Treated Participants (P05550)

This is a randomized, placebo-controlled, 3-period crossover, balanced, single-site, third party-blind study of preladenant (SCH 420814) in patients with Parkinson disease (PD) to be condu...

Safety and Pharmacokinetics of Ifetroban in Hepatorenal Syndrome Patients

Cumberland Pharmaceuticals Inc. (CPI) is developing ifetroban for treatment of hepatorenal syndrome (HRS) and proposes to conduct a study in hospitalized adult patients with HRS to assess...

Guanfacine in Children With Tic Disorders

The goal of this pilot study is to obtain preliminary information on the tolerability and efficacy of extended release guanfacine (trade name Intuniv) in children with Tourette Disorder (T...

Outcome of Atrial Fibrillation Ablation After Permanent Pulmonary Vein Antrum Isolation With or Without Proven Left Atrial Posterior Wall Isolation

Objective: This prospective study aims to examine the outcome of atrial fibrillation (AF) ablation after permanent pulmonary vein antrum isolation or pulmonary vein antrum isolation plus l...

MAESTRO-OL: Macitentan in Eisenmenger Syndrome To Restore Exercise Capacity (Open-Label)

Long-term study to evaluate if macitentan is safe, tolerable and efficient enough to be used for treatment of Eisenmenger syndrome.

Antithrombotic Triple Therapy in Humans

Background:The acute coronary syndrome (ACS) is a complication of coronary artery disease (CAD) and associated with increased mortality. Dual antiplatelet therapy of acetylsalicylic acid (...

Randomized Evaluation of Long Term Anticoagulant Therapy (RE-LY) With Dabigatran Etexilate

The primary objective of this trial is to demonstrate the efficacy and safety of dabigatran etexilate in patients with non-valvular atrial fibrillation for the prevention of stroke and sys...

Ophthalmologic Safety Study of Pramipexole Immediate Release (IR) Versus Ropinirole in Early Parkinson's Disease (PD) Patients

To determine if there is any difference in the presence of retinal deterioration in PD patients treated with pramipexole IR versus ropinirole as monitored by comprehensive ophthalmologic a...

Survey of Patients With Idiopathic Orbital Inflammation Syndrome

The purpose of this study is to characterise the clinical features, histopathology and the treatment outcomes of patients with idiopathic orbital inflammation syndrome.

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

This study is a research study involving subjects who are diagnosed with a malignant disease, that has either failed standard therapy or is unlikely to be cured with standard non-transplan...

Medical and Biotech [MESH] Definitions

A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulse conducts to the HEART VENTRICLES via an accessory pathway located between the wall of the right or left atria and the ventricles, known as the bundle of Kent. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).

A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)

Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)

A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.

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