Atrial Fibrillation and WolffParkinsonWhite Syndrome WPW - Biotech, Pharma and Life Science Channel

07:08 EST 22nd January 2017 | BioPortfolio

PubMed Articles [8458 Associated PubMed Articles listed on BioPortfolio]

The relationship between right-to-left shunt and brain white matter lesions in Japanese patients with migraine: a single center study.

There may be a link between right-to-left shunt (RLs) and brain white matter lesions (WMLs) in patients with migraine. In this study, we assessed the relationship between WMLs and RLs in Japanese migr...

Clinical assessment and train-of-four measurements in critically ill patients treated with recommended doses of cisatracurium or atracurium for neuromuscular blockade: a prospective descriptive study.

Despite few studies, a monitoring of a neuromuscular blockade with a train of four (TOF) is recommended in intensive care unit (ICU). Our objective was to compare the results of ulnar and facial TOF m...

Influence of hydrogenated oil as cocoa butter replacers in the development of sugar-free compound chocolates: Use of inulin as stabilizing agent.

The effect of the addition of inulin as a surfactant or stability agent on white compound chocolate sweetened with sucralose and Stevia was studied. Samples were stored at 7, 15 and 30°C during 100da...

Phenolics, antioxidant capacity and bioaccessibility of chicory varieties (Cichorium spp.) grown in Turkey.

In this study, the changes in phenolics, anthocyanin, antioxidant capacity, and bioaccessibility of chicory varieties (Cichorium spp.) in Turkey were investigated. A total of 19 phenolic standards wer...

Changes in the antigenicity and allergenicity of ovalbumin in chicken egg white by N-acetylglucosaminidase.

Ovalbumin (OVA), an (hen) egg allergen, is one of the most abundant glycoprotein allergens associated with IgE-mediated hypersensitivity through the T-helper type 2 immune response. The effect of degl...

The cadmium and lead content of the grain produced by leading Chinese rice cultivars.

The cadmium (Cd) and lead (Pb) content in both white and wholemeal flour milled from 110 leading rice cultivars was assessed. The white flour Cd content ranged from

A Validation Study of the International Consensus Diagnostic Criteria for Neuroleptic Malignant Syndrome.

Neuroleptic malignant syndrome requires prompt recognition for effective management, but there are no established diagnostic criteria. This is the first validation study of recently published internat...

Methotrimeprazine-Associated Stevens-Johnson Syndrome in 2 Ashkenazi Jewish Patients.

Bermuda triangle; heart failure, atrial fibrillation, and vitamin D deficiency.

The Curves Exercise Suppresses Endotoxemia in Korean Women with Obesity.

Obesity and metabolic syndrome is a worldwide pandemic and associated with high cardiovascular risk. Metabolic endotoxemia (ME) is thought to be an underlying molecular mechanism. It triggers toll-lik...

News Articles [3592 Associated News Articles listed on BioPortfolio]

Genetic Literacy Project’s Top 6 Stories for the Week, January 23, 2017

CDC Confirms Seoul Virus in 8 Patients

In rare cases, infection can also lead to a type of acute renal disease called Hemorrhagic Fever with Renal Syndrome (HFRS). ? CDC Confirms Seoul Virus in 8 Patients  Info on Seoul Virus (CDC)&nb...

T-6b allocates more assimilation product for oil synthesis and less for polysaccharide synthesis during the seed development of Arabidopsis thaliana

As an Agrobacterium tumefaciens T-DNA oncogene, T-6b induces the development of tumors and the enation syndrome in vegetative tissues of transgenic plants. Most of these effects are related to increas...

UPDATE 2-Trump, in Oval Office, signs first order on Obamacare

WASHINGTON, Jan 20 (Reuters) - President Donald Trump directed government agencies on Friday to freeze regulations and take steps to weaken Obamacare, using his first hours in the White House to make ...

Trump Stays Silent On Health Law In Speech, Then Sets Tone For Repeal

Health care agenda missing from the inaugural address and on the new White House website.

Trump Administration Is Silent On Plans For Overhauling Health Law

Health care agenda missing from the inaugural address and on the new White House website.

European Commission grants ProMetic’s PBI-4050 orphan drug status for Alström Syndrome

LAVAL, QC- The European Commission is granting ProMetic Life Sciences lead drug candidate, PBI-4050, an orphan drug designation as a treatment for Alström Syndrome (AS). The designation is based on ...

Brief Roundup Part II - Conatus (CNAT) and Corcept (CORT)

In Part 1, we wrote our brief thoughts about BioMarin (BMRN) and Capricor (CAPR). Part 2 is focused on Conatus (CNAT) and Corcept (CORT). Conatus Pharmaceutical (CNAT)Conatus recently announced a coll...

Could social media be a whistle-blower for the next disease outbreak?

A study, published in The Journal of Infectious Diseases, found evidence of the early stages of Ebola and Middle East Respiratory Syndrome (MERS) outbreaks through social media.

Enzyvant licenses DiGeorge syndrome therapy from Duke University

Duke University granted Enzyvant Sciences GMBH exclusive global rights to develop and sell RVT802, a tissue-based therapy in Phase III trials for the rare congenital immunodeficiency disease complete ...

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Companies [150 Associated Companies listed on BioPortfolio]


We are a biopharmaceutical company focused on developing a portfolio of internally discovered product candidates for the potential treatment of central nervous system (CNS) disorders. We also have a p...

LuxCath LLC

LuxCath is a leader in catheter-based, real-time, optical tissue-electrode contact assessment, lesion progression monitoring, and lesion visualization for cardiac ablation. LuxCat...

Velicept Therapeutics, Inc.

Velicept Therapeutics, Inc. is a privately held, clinical development company focused on advancing best-in-class compounds with the potential to fill unmet medical needs. Its lead...

Alexion Pharmaceuticals Inc.

Alexion is a global biopharmaceutical company focused on developing and delivering life-transforming therapies for patients with devastating and rare disorders. Alexion developed ...

Prana Biotechnology

Prana Biotechnology has developed a proprietary library of class-leading chemical compounds. This library is combined with a drug development program to explore novel therapeutics in multiple disease ...

PathMaker Neurosystems Inc.

PathMaker Neurosystems Inc. is a clinical-stage neuromodulation company founded to commercialize recent breakthrough advances in the development and clinical application of trans-...

Delaware Park

Delaware Park is a multi-level gaming facility, offering guests more than 2,300 exciting slot machines, live table games including poker, blackjack, craps and roulette, cash and t...

Cigna Corporation and WESTMED Medical Group

WESTMED Medical Group is a large multi-specialty group medical practice, with headquarters in Purchase, NY. It is staffed by a team of 318 physicians dedicated to providing coordi...

Neuropore Therapies, Inc.

Neuropore Therapies is developing novel small molecule therapeutics to treat and slow the progression of neurodegenerative disorders such as Alzheimer’s and Parkinson’s ...

Dannon Company, Inc.

The Dannon Company is America's founding national yogurt company and continually leverages its expertise to develop and market innovative cultured fresh dairy products in the Unit...

Clinical Trials [5024 Associated Clinical Trials listed on BioPortfolio]

tDCS on PD Cognition

Parkinson's disease (PD) has been classically regarded as a "movement disorder", so earlier work has focused on treating motor symptoms only. As PD patients now have longer life expectancy...

Pharmacogenomics of the Variability in the In Vivo Response to Glucocorticoids

This study evaluates the effect of acute administration of oral prednisone in white blood cells counts and glucose tolerance and the relationship of these measures with changes in gene exp...

Study of Iguratimod in Sjögren's Syndrome

A single-center, self-control, open-label study of efficacy and safety of Iguratimod in patients with Sjögren's Syndrome

Diagnosis of Bladder Pain Syndrome / Interstitial Cystitis

To identify new, simple and reliable biomarkers for bladder pain syndrome/interstitial cystitis (BPS/IC) for diagnosis of this disease.

Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation

Title: Optimal Delay Time to Initiate Anticoagulation after Ischemic Stroke in Atrial Fibrillation (START): a pragmatic, adaptive randomized clinical trial. Primary Objective: ...

Severe ARDS: Generating Evidence

An assessment of early management of moderate-severe ARDS in the United States, including ventilator management and use of rescue therapy.

Mobile Health Strategies for Veterans

The purpose of this study is to determine whether text messages/messaging (TM) or a mobile application (app), compared with an educational website-control provided to all Veterans, can imp...

Comparing the Therapeutic Efficacy and Safety of DA-9701 With Domperidone in Patients With Parkinson's Disease

This study will evaluate the therapeutic efficacy and safety of DA-9701 with domperidone in patients with Parkinson's disease

Nigrosomal Iron Imaging in Parkinson's Disease

Prospective observational study to compare sensitivity of 3T functional Magnetic Resonance Imaging (3T fMRI) at diagnosing Parkinson's Disease (PD) against the benchmark DaTScan diagnostic...

Protein Bioavailability of Wolffia Globosa (Mankai); Acute Test Meal Effects

The investigators aim to test the protein bioavailability of new specific developed strain of duckweed [Wolffia globose, Mankai] , an aquatic plant, which might serve as a protein source a...


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Medical and Biotech [MESH] Definitions

A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulse conducts to the HEART VENTRICLES via an accessory pathway located between the wall of the right or left atria and the ventricles, known as the bundle of Kent. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).

A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)

Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)

A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.

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