Atrial Fibrillation and WolffParkinsonWhite Syndrome WPW - Biotech, Pharma and Life Science Channel

17:53 EDT 19th September 2014 | BioPortfolio

PubMed Articles [8484 Associated PubMed Articles listed on BioPortfolio]

Retraction notice to 'Phenolic composition, antioxidant properties, and endothelial cell function of red and white cranberry fruits' Food Chem. 157 (2014) 540-552.

Impact of childhood obesity on cardiac structure and function.

Obesity prevalence is still on the rise worldwide in both adults and children. In adults, obesity is a significant cardiovascular risk factor associated with increased morbidity and mortality. In chil...

Cerebral thrombosis and myeloproliferative neoplasms.

Myeloproliferative neoplasms (MPN) are acquired clonal disorders characterized by the proliferation of bone marrow myeloid cells. Different somatic mutations have been recently associated with MPN, th...

Genetic heterogeneity in Alzheimer disease and implications for treatment strategies.

Since the original publication describing the illness in 1907, the genetic understanding of Alzheimer's disease (AD) has advanced such that it is now clear that it is a genetically heterogeneous condi...

Enhancing Approaches to Therapeutic Hypothermia in Patients with Sudden Circulatory Arrest.

Cardiac arrest is common and causes substantial morbidity and mortality. Despite advances in prevention and resuscitation, most patients remain unconscious and survival remains poor. Therapeutic hypot...

Judicious use of biologicals in juvenile idiopathic arthritis.

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disorder that may cause joint destruction. Biological treatments targeting specific cytokines and cell interactions have transformed the o...

Understanding Parkinson disease: An evolving case study.

Thirty years ago, Parkinson disease was described as a shortage of the neurotransmitter dopamine. Today, understanding of this disorder includes possible genetic influences, premorbid and nonmotor iss...

Infectious Diseases and Tropical Disease Pathology: SY16-2B PEDIATRIC CEREBRAL MALARIA PATHOLOGY.

Malaria kills more than half a million children a year in sub-Saharan Africa despite the availability of effective combination drug therapy, efficacy of bed nets, and environmental control measures. C...

Coexistence of psoriasis, and alopecia areata with trachyonychia in a pediatric patient with Turner Syndrome.

Turner syndrome is a genetic disorder characterized by abnormalities of the X chromosome. An association with many autoimmune diseases is described as well as skin diseases such as psoriasis, vitiligo...

Extramedullary relapse of acute linfoblastic leukemia: report of a case.

The superior vena cava syndrome (SVCS) is considered an emergency and requires immediate treatment; therefore, the etiologic diagnosis is essential before deciding on its implementation. The managemen...

News Articles [3654 Associated News Articles listed on BioPortfolio]

Xarelto Makers Seek Dismissal of Cases Brought in Philadelphia, Notes Rottenstein Law Group LLP

Defendant Xarelto manufacturers want several lawsuits dismissed from Pennsylvania state court, arguing that there is no connection with the state. Rockville Centre, NY (PRWEB) September 19, 2014 Acco...

Cynapsus Therapeutics Inc. : Cynapsus Therapeutics Announces Change of Auditor

PRESS RELEASE Cynapsus Therapeutics Announces Change of Auditor September 19, 2014 TORONTO - Cynapsus Therapeutics Inc. ("Cynapsus" or the "Company") (TSX...

Obama Orders Plan To Reduce Peril Of Antibiotic Resistance

The measures include incentives to develop new drugs, tighter control of existing ones and better tracking of resistant microbes. "Super bugs" are thought to cause 23,000 deaths and two million illnes...

EyeForPharma Multichannel Marketing Summit 2014: Lundbeck's Tim White on customer interaction, apps and buzzwords

Tim White is head of global customer interaction at Lundbeck. The Pharma Letter spoke to him at the EyeForPharma Multichannel Marketing Summit about how his role can be integrated into research and de...

PREVAIL Update Less Positive for Watchman

(MedPage Today) -- More data revealed more failure for the Watchman left atrial appendage closure device, but, again, interventional cardiologists attending the Transcatheter Cardiovascular Therapeuti...

Biotie: Selincro enters the market in France

BIOTIE THERAPIES CORP.            STOCK EXCHANGE RELEASE      19 September 2014   at 11.30 a.m. Biotie: Selincro enters the market in France Biotie today announced that ...

biOasis begins MPS II trial with Lysosomal storage disease expert Dr. Maurizio Scarpa and The Brains for Brain Foundation

biOasis Technologies, the pioneering biopharmaceutical company focused on the delivery of therapeutic drugs across the blood-brain barrier (BBB), has announced a study to investigate the ability of it...

New MHA white paper focuses on major role of PAC Provider within ACOs

Managed Health Care Associates, Inc., a leading health care services and technology company focused on the alternate site health care provider marketplace, today announced the release of a new white p...

Obama launches multi-strategy attack on antibiotic resistance

The White House on 18 September said it was serious about combating antimicrobial resistance (AMR) and issued three documents laying out a multi-strategy plan of attack, which officials said demonstra...

TGI Friday! Our weekly round-up of recently published research abstracts | 19 September 2014

From Neuroendocrinology Letters, 30 June 2014 [Epub ahead of print]. Clinical endocannabinoid deficiency (CECD) revisited: Can this concept explain the therapeutic benefits of cannabis in migraine, fi...

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Companies [118 Associated Companies listed on BioPortfolio]

Tenax Therapeutics, Inc.

Tenax Therapeutics, Inc. (formerly Oxygen Biotherapeutics) is a specialty pharmaceutical company focused on developing and commercializing a portfolio of products for the critical...

DC Devices, Inc.

DC Devices, Inc. is dedicated to revolutionizing the treatment of heart failure with first-in-class structural heart devices. The company has developed the world’s first tran...

Lysosomal Therapeutics Inc.

Lysosomal Therapeutics Inc. (LTI) is dedicated to innovative small-molecule research and development in the field of neurodegeneration, yielding new treatment options for patie...

Clear Seas Communications

Jarden Corporation is a leading provider of a diverse range of consumer products with a portfolio of over 120 trusted, quality brands sold globally. Jarden operates in three prima...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Life Stem Genetics, Inc.

Life Stem Genetics (“LSG”) is a progressive healthcare company focused on Adult Stem Cell (ASC) healing therapies. For decades, stem cells have been utilized in the succ...

Life Stem Genetics Inc.

Life Stem Genetics (“LSG”) is a progressive health care company that focuses on healing with a patient’s own “Stem Cells”. Stem Cells for years have been ...

Baylor Scott & White Health

Baylor Scott & White Health is a not-for-profit health care system with total assets of $8.3 billion* and the vision and resources to offer its patients continued exceptional care...

Weill Cornell Medical College

Weill Cornell Medical College, Cornell University's medical school located in New York City, is committed to excellence in research, teaching, patient care and the advancement of the art and sci...

Sea-licious™

Karlene Karst, a Registered Dietician, is a leading health specialist in both nutrition and natural medicine. She is the co-author of the national best seller “Healthy ...

Clinical Trials [3110 Associated Clinical Trials listed on BioPortfolio]

A Multicenter VESIcare® Efficacy and Safety Study for the Treatment of Urgency Associated With Overactive Bladder (OAB)

The purpose is to evaluate the efficacy of 5 and 10mg VESIcare® (solifenacin succinate) in patients with urgency who have overactive bladder syndrome.

Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That is Recurrent, Metastatic, or Cannot Be Removed by Surgery

This phase I/II trial studies the side effects and best dose of recombinant interleukin-12 when given together with cetuximab and to see how well they work in treating patients with squamo...

Anti-CD19 White Blood Cells for Children and Young Adults With B Cell Leukemia or Lymphoma

Background: - Although progress has been made in treating children with B-cell cancers such as leukemia or lymphoma, many children do not respond to the standard treatments. One possible ...

Shocking Therapy for Chronic Pelvic Pain Syndrome

Chronic prostatitis/chronic pelvic pain syndrome is an extremely common urologic diagnosis and accounts for approximately 2 million outpatient visits to urology practices in the United Sta...

Ischemia Care Biomarkers of Acute Stroke Etiology (BASE)

The proposed study will validate the clinical use of new biomarker blood tests to identify blood components that may differentiate between diverse stroke etiologies and clinical outcomes a...

12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D)

Irritable Bowel Syndrome with diarrhoea (IBS-D) is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort and diarrhoea. This trial aims ...

Etanercept in Kawasaki Disease

The purpose of this study is to determine whether Etanercept (Enbrel) when used in conjunction with IVIG and aspirin, improves treatment response to IVIG in patients with Kawasaki Disease....

Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy

The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21.

A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)

This multi-center, randomized, double-blind, 3-arm, parallel-group, placebo-cont rolled study will evaluate the efficacy and safety of RG1662 in adults and adole scents with Down syndrome....

Pre-Transplant 5-Azacitidine In Patients With High-Risk Myelodysplastic Syndrome Who Are Candidates For Allogeneic Hematopoietic Cell Transplant

The purpose of this study is to find out if treating people who have high-risk myelodysplastic syndrome (MDS) with 5-Azacitidine (Vidaza) prior to their allogeneic hematopoietic cell trans...

Medical and Biotech [MESH] Definitions

A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulse conducts to the HEART VENTRICLES via an accessory pathway located between the wall of the right or left atria and the ventricles, known as the bundle of Kent. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).

A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)

Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)

A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.

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