Atrial Fibrillation and WolffParkinsonWhite Syndrome WPW - Biotech, Pharma and Life Science Channel

23:55 EST 21st December 2014 | BioPortfolio

PubMed Articles [8252 Associated PubMed Articles listed on BioPortfolio]

Next Generation Semiconductor Based-Sequencing of a Nutrigenetics Target Gene (GPR120) and Association with Growth Rate in Italian Large White Pigs.

The GPR120 gene (also known as FFAR4 or O3FAR1) encodes for a functional omega-3 fatty acid receptor/sensor that mediates potent insulin sensitizing effects by repressing macrophage-induced tissue inf...

Novel Polymorphisms in Porcine 3'UTR of the Leptin Gene, Including a Rare Variant within Target Sequence for MIR-9 Gene in Duroc Breed, not Associated with Production Traits.

The leptin gene (LEP) is considered as a functional candidate for production traits in livestock due to its crucial role in energy homeostasis. Because polymorphisms in regulatory sequences may affect...

Chemical composition and antioxidant activity of seven cultivars of guava (Psidium guajava) fruits.

The antioxidant activity and identification of phenolic compounds of seven edible guava (Psidium guajava) cultivars that varied in colour from white to pink were examined. In the DPPH assay all four p...

Weight Loss Attitudes and Social Forces in Urban Poor Black and White Women.

To explore differences between Blacks and Whites in perceived influences on weight-related behaviors among obese urban poor women.

Foam Padding in Casts Accommodates Soft Tissue Swelling and Provides Circumferential Strength After Fixation of Supracondylar Humerus Fractures.

Varying casting techniques are used after surgical treatment of pediatric supracondylar humerus fractures. The goals are to maintain fracture reduction, while accommodating soft tissue swelling and mi...

Volatile substance misuse deaths in Washington State, 2003-2012.

Abstract Background: Volatile substance misuse (VSM - also known as huffing or sniffing) causes some deaths, but because there are no specific cause-of-death codes for VSM, these deaths are rarely tab...

Prenatal Screening: An Ethical Agenda for the Near Future.

Prenatal screening for foetal abnormalities such as Down's syndrome differs from other forms of population screening in that the usual aim of achieving health gains through treatment or prevention doe...

Guidelines on genetic evaluation and management of Lynch syndrome.

Recommendations for increasing alkaline comet assay reliability in plants.

In plants, an increasing interest for the comet assay was shown in the last decade. This versatile technique appears to be promising to detect the genotoxic effect of pollutants and to monitor the env...

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome.

Previously, a healthy Nordic diet (ND) has been shown to have beneficial health effects close to those of Mediterranean diets.

News Articles [3385 Associated News Articles listed on BioPortfolio]

First successful vaccination against 'mad cow'-like wasting disease in deer

(NYU Langone Medical Center / New York University School of Medicine) Researchers at NYU Langone Medical Center and elsewhere say that a vaccination they have developed to fight a brain-based, wasting...

Aging white lion euthanized at Ohio zoo

An aging white lion given to the Cincinnati Zoo by performers Seigfried & Roy had to be euthanized because of age-related health issues.

MKSAP: 76-year-old woman with a headache

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 76-year-old woman is evaluated for a 1-day history of headache, left eye pain, nausea...

Xarelto Blood Thinner Lawsuits Consolidated in Louisiana Federal Court -- Patients Allege Xarelto Linked to Serious Bleeding Risk

Wendy R. Fleishman of the national plaintiffs' law firm Lieff Cabraser Heimann & Bernstein, LLP, announced today that nearly two dozen lawsuits filed against Johnson & Joh...

Energy Textiles Launches Celliant Revitalizing Bedsheets

Celliant Revitalizing Bedsheets are designed to be thermoregulating and circulation-enhancing. Tampa, FL (PRWEB) December 19, 2014 Energy Textiles is excited to announce that Celliant Revitalizing Be...

Research shows E.B. White was right in 'Charlotte's Web'

Before Charlotte the spider spelled the word "humble" in her web to describe Wilbur the pig, she told Templeton the rat that the word meant "not proud." That's probably what most people say if you put...

LYNPARZA(TM) Approved By The US Food and Drug Administration For The Treatment Of Advanced Ovarian Cancer In Patients With Germline BRCA-mutations

WILMINGTON, Del., Dec. 19, 2014 /PRNewswire/ -- AstraZeneca today announced that the US Food and Drug Administration (FDA) has approved LYNPARZA™ (olaparib) capsules. LYNPARZA is the first ...

Initial management of Parkinson's disease

Parkinson’s disease is one of the most common neurodegenerative disorders seen in the United States and United Kingdom. The disease is characterised by two processes—cellular degeneration and the....

LYNPARZA™ Approved By The US Food and Drug Administration For The Treatment Of Advanced Ovarian Cancer In Patients With Germline BRCA-mutations

WILMINGTON, Del., Dec. 19, 2014 /PRNewswire/ -- AstraZeneca today announced that the US Food and Drug Administration (FDA) has approved LYNPARZA™ (olaparib) capsules. LYNPARZA is the first ...

Biosense Webster, Inc. Launches Outcomes-Based, Risk-Sharing Program to Reinforce Significant Patient Benefits Demonstrated by Company’s Leading Contact Force Therapy

Biosense Webster, Inc., a worldwide leader in the diagnosis and treatment of cardiac arrhythmias, announced the launch of the BIOSENSE WEBSTER ADVANTAGESM Program, an outcomes-bas...

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Companies [124 Associated Companies listed on BioPortfolio]

Tenax Therapeutics, Inc.

Tenax Therapeutics, Inc. (formerly Oxygen Biotherapeutics) is a specialty pharmaceutical company focused on developing and commercializing a portfolio of products for the critical...

Yumanity Therapeutics

Yumanity Therapeutics is transforming drug discovery for neurodegenerative diseases caused by protein misfolding. Formed in 2014 by renowned biotech industry leader, Tony Coles, M...

Ideal Protein

Ideal Protein is a medical weight loss program that was developed 23 years ago by physician Dr. Tran Tien Chanh. Ideal Protein is a medical solution protocol based on validated sc...

Team Red, White and Blue

Team Red, White and Blue (Team RWB) is a registered 501(c)3 nonprofit organization with headquarters in Chicago, IL. Team RWB’s mission is to enrich the lives of Americaâ€...

Cortendo AB

Cortendo AB is a biopharmaceutical company headquartered in Göteborg, Sweden. Its stock is publicly traded on the NOTC-A-list (OTC) in Norway. Cortendo is a pioneer in the fiel...

Innocrin Pharmaceuticals, Inc.

Innocrin discovers and develops novel, best-in-class oral inhibitors of CYP17 lyase, a validated enzyme target for the treatment of castration-resistant prostate cancer. VT-464 an...

Nolan Auerbach & White

DC Devices, Inc.

DC Devices, Inc. is dedicated to revolutionizing the treatment of heart failure with first-in-class structural heart devices. The company has developed the world’s first tran...

Lysosomal Therapeutics Inc.

Lysosomal Therapeutics Inc. (LTI) is dedicated to innovative small-molecule research and development in the field of neurodegeneration, yielding new treatment options for patie...

Clear Seas Communications

Jarden Corporation is a leading provider of a diverse range of consumer products with a portfolio of over 120 trusted, quality brands sold globally. Jarden operates in three prima...

Clinical Trials [3261 Associated Clinical Trials listed on BioPortfolio]

Blood Cell Response to Exercise

Moderate exercise is recommended to improve cardiovascular health in obese and overweight people particularly with metabolic syndrome (MetS) that have hypertension, elevated fasting blood ...

PET Study of Non-Motor Symptoms of Parkinson Disease

This research plan is focused on neurochemical positron emission tomography (PET) studies of Parkinson disease (PD). PD is the most common neurodegenerative movement disorder, and consider...

Ph 2 Trial to Evaluate Safety & Efficacy of RM-493 in Obese Patients With Prader-Willi Syndrome

The purpose of this study is to evaluate the effects of a once daily subcutaneous (SC) injectable formulation of RM-493 in obese subjects with Prader-Willi syndrome on tolerability, weight...

Phase II Hedgehog Inhibitor for Myelodysplastic Syndrome (MDS)

This study is being done to see how safe an investigational drug is and test how well it will work to help people with refractory/relapsed myelodysplastic syndrome (MDS) or chronic myelomo...

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Ocular Melanoma

Background: - The NCI Surgery Branch has developed an experimental therapy that involves taking white blood cells from patients' tumors, growing them in the laboratory in large numbers, a...

PV Reconnection After PVAI at Different Power Settings and Adenosine Provocation

In this prospective randomized study, we aim to compare the rate of PV reconnection following PVAI performed at different energy settings (30 Watts vs 40 Watts) where dormant PV conduction...

Clinical Evaluation of the SEQureDx T21 Test In High Risk Pregnancies

Whole blood samples will be collected from high-risk pregnant women to validate the clinical performance of the SEQureDx Trisomy 21 Test.

Gene Therapy for WAS

This is a phase I/II study to evaluate the safety and efficacy of Hematopoietic Stem Cell genetherapy for the Wiskott-Aldrich Syndrome.

Study of MLN9708 as Maintenance Therapy for Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) in Remission

The goal of this clinical research study is to learn if ixazomib can prevent AML or MDS from coming back in patients who are in remission. The safety of this drug will also be studied.

Safety Study of TPI-287 to Treat CBS and PSP

The purpose of this study is to determine the safety and tolerability [maximum tolerated dose (MTD) within planned dosing range] of intravenous (IV) infusions of TPI 287 administered once ...

Medical and Biotech [MESH] Definitions

A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulse conducts to the HEART VENTRICLES via an accessory pathway located between the wall of the right or left atria and the ventricles, known as the bundle of Kent. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).

A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)

Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)

A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.

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