Autoimmune hepatitis - Biotech, Pharma and Life Science Channel
PubMed Articles
Treatment for hepatitis C virus-induced portal hypertension in leukemic children.
Children with acute leukemia are at high risk of hepatitis C infection, either by immunosuppression secondary to chemotherapy or by multiple transfusions of blood products during the course of the dis...
Genetics and epigenetics of liver cancer.
Hepatocellular carcinoma (HCC) represents a major form of primary liver cancer in adults. Chronic infections with hepatitis B (HBV) and C (HCV) viruses and alcohol abuse are the major factors leading...
Successful treatment with rituximab of an infant with refractory autoimmune hemolytic anemia.
Autoimmune hemolytic anemia (AIHA) is a rare disease in infants, for which steroids are recognized as a first-line therapy for patients. Rituximab, a humanized monoclonal antibody raised against CD20,...
Pathophysiology and management of primary immune thrombocytopenia.
Primary immune thrombocytopenia, or idiopathic thrombocytopenic purpura (ITP), is an autoimmune disorder characterized by isolated thrombocytopenia due to accelerated platelet destruction and impaired...
PURPOSE: Suppressor of cytokine signaling-1 (SOCS-1) is a negative regulator of the Janus kinase/signal transducer and activation of transcription pathway. The purpose of this study was to investigate...
Hoof Nail Deformity: a previously unknown hereditary nail malformation.
A 54-year-old man who was followed by dermatology regarding a personal history of malignant melanoma was found to have an incidental nail abnormality affecting his bilateral second toenails. The malfo...
Effect of nucleoside analog use in patients with hepatitis B virus-related hepatocellular carcinoma.
AIMS: The aims of the present study were to examine the effect of nucleoside analog (NA) therapy on clinical outcome in patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) who...
Taking nucleos(t)ide analogues is a major antiviral therapy for chronic hepatitis B infection. The problem with this treatment is the selection for drug-resistant mutants. Currently, identification of...
Hepatitis C virus (HCV) is a global health concern infecting 170 million people worldwide. Previous studies indicate that the extract from milk thistle known as silymarin and its main component silibi...
News Articles
The Genetic Basis Of Six Autoimmune Diseases Investigated By Researchers
Researchers from Queen Mary, University of London have led the largest sequencing study of human disease to date, investigating the genetic basis of six autoimmune diseases. The exact cause of these d...
Going live: Immune cell activation in multiple sclerosis
Biological processes are generally based on events at the molecular and cellular level. To understand what happens in the course of infections, diseases or normal bodily functions, scientists would ne...
Biological processes are generally based on events at the molecular and cellular level. To understand what happens in the course of infections, diseases or normal bodily functions, scientists would ne...
Ignyta acquires Actagene Oncology
US company Ignyta, Inc has acquired Actagene Oncology, Inc, a San Diego based biotechnology company founded in February 2013 that was developing personalised medicines for cancer indications based on...
Galapagos and AbbVie extend collaboration to include Crohn’s disease
Galapagos NV and AbbVie have agreed to extend their GLPG0634 clinical development collaboration to include Crohn’s disease. Galapagos will fund and complete a Phase 2 programme in the disease design...
Sinovac Beijing Obtains China GMP Certificate Under the New GMP Guidelines
BEIJING, May 24, 2013 /PRNewswire/ -- Sinovac Biotech Ltd. (NASDAQ: SVA), a leading provider of biopharmaceutical products in China, announced that Sinovac Beijing, the main operating subsidiary...
Study Evaluates Prevalence Of Multiple Health Concerns Among Patients With The Alopecia Areata
JAMA Dermatology Study Highlights A study by Kathie P. Huang, M.D., of Brigham and Women's Hospital, Boston, and colleagues examined the prevalence of comorbid (co-existing) conditions among patients...
Autoantibodies may form basis of lupus diagnostic test
Scientists believe a new diagnostic test for lupus could be developed by looking for the presence of certain antibodies in the blood.Antibodies are proteins manufactured by the immune system to help i...
Going live -- immune cell activation in multiple sclerosis
(Max-Planck-Gesellschaft) Scientists from the Max Planck Institute of Neurobiology in Martinsried have now presented not one, but two studies introducing new indicator molecules which can visualize th...
J&J downplays biosimilar competition
Uptake in Korea of Remsima infliximab, a biosimilar version of autoimmune drug Remicade infliximab, has been "relatively slow," according to Kim Taylor, company group chairman, pharmaceuticals, Asia P...
Events
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Companies
Transgene (NYSE-Euronext: TNG), a member of the Institut Mérieux Group, is a biopharmaceutical company. It creates, develops and manufactures targeted immunotherapeutics for th...
Ignyta, Inc., located in San Diego, California, is a personalized medicine company developing revolutionary new products and services to customize diagnosis and treatment of patie...
Neovacs is a French biotechnology company focused on active immunotherapy for autoimmune and inflammatory diseases and cancer. Neovacs is a spin-off from Université Pierre et Marie Curie in P...
Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...
Defymed is a spin -off of the “Centre Europeen d’etude du Diabete” (CeeD) which has been working on the conception of a bio-artificial pancreas since 1996. This work was ca...
ERBA Diagnostics, Inc. (www.erbadiagnostics.com), headquartered in Miami, Florida, is a fully integrated in vitro diagnostics company that develops, manufactures and distributes i...
Alvine Pharmaceuticals, Inc. is a private, clinical-stage, specialty biopharmaceutical company located in San Carlos, CA, focused on the development of biologics targeting autoimm...
Elan Corporation, plc is a neuroscience-based biotechnology company focused on discovering and developing advanced therapies in neurodegeneration and autoimmune diseases, and real...
Seattle Genetics is a clinical-stage biotechnology company focused on the development and commercialization of monoclonal antibody-based therapies for the treatment of cancer and...
Opsona is a leading immunology drug development company, focused on novel therapeutic approaches to key targets of the innate immune system associated with a wide range of majo...
Clinical Trials
Immune Response to Hepatitis C Virus
This study will identify and characterize immune factors involved in hepatitis C infection and elimination of the virus. Individual responses to hepatitis C infection vary; some people ar...
Pilot Trial to Assess Effect of CNI Conversion of Efalizumab on T Reg Cells
The purpose of this pilot trial is to determine whether a conversion from calcineurin inhibitors (CNI) and mycophenolate mofetil (MMF) to a regimen consisting of efalizumab and sirolimus i...
Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy
Background: - Drugs given to treat cancer (chemotherapy) can weaken the human immune system. But it can also become weaker because of aging. Interleukin (IL)-7, a molecule produced natura...
A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010 AM1)
This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....
The purpose of the study is to determine the safety, pharmacokinetics and efficacy of orally administered VX-135 with ribavirin in treatment naive subjects with chronic hepatitis C infecti...
The purpose of this study is to assess the efficacy of a short course of therapy (24 weeks) versus standard 48 week treatment in previously untreated adult participants with chronic hepati...
TMC435-TiDP16-C112 - Interaction Trial With Antidepressants
The purpose of this study is to investigate the effect of steady-state concentrations of TMC435 150mg q.d. (once a day) on the steady-state pharmacokinetics of escitalopram 10 mg q.d., and...
HRN-003 STUDY SYNOPSIS OBJECTIVE: To compare the Sustained Virologic Response (SVR) of PEGIntron plus ribavirin among patients receiving a fixed dose of PEGIntron versus weighted-adjusted...
Objectives: Primary To evaluate the safety, tolerability, and efficacy of Peginterferon a-2a plus Ribavirin for the treatment of chronic hepatitis C (CHC) infection in persons co-infected...
Scleroderma is an autoimmune disease of unknown origin. Recently, the role of environmental factors, and particularly toxic drug exposure, in the genesis of scleroderma has been suggested....
Videos
AutoImmune Hepatitis The Basics 05/03/20
Created on March 10, 2011 using FlipShare.
Medical and Biotech [MESH] Definitions
Hepatitis A Antigens
Antigens produced by various strains of HEPATITIS A VIRUS such as the human hepatitis A virus (HEPATITIS A VIRUS, HUMAN).
Hepatitis A Antibodies
Antibodies to the HEPATITIS A ANTIGENS including antibodies to envelope, core, and non-structural proteins.
Hepatitis Delta Antigens
Antigens produced by various strains of HEPATITIS D VIRUS.
Helicobacter Hepaticus
A species of HELICOBACTER that colonizes the CECUM and COLON of several strains of MICE, and is associated with HEPATITIS and carcinogenesis.
Anellovirus
A free-floating DNA virus genus, unattached to any family, comprising several species of hepatitis-related viruses.
