Autosomal Dominant Polycystic Kidney Disease ADPKD - Biotech, Pharma and Life Science Channel
PubMed Articles
The role of heavy-light-hole mixing on the optical initialization of hole spin in InAs quantum dots.
The initialization of a resident hole spin by the absorption of a circularly polarized light at resonance involves the formation of an excited state called a trion state. For a pure heavy hole, this o...
Somatoform pruritus : A psychosomatic disease model.
Pruritus is an interdisciplinary symptom that is difficult to diagnose and treat. When there is no evidence of an organic cause, it is challenge for both the patient and the doctor. Itching affecting...
Chorea due to TITF1/NKX2-1 mutation: phenotypical description and therapeutic response in a family.
INTRODUCTION. Chorea due to a mutation in the TITF1 gene, which is also known as benign hereditary chorea, is an autosomal dominant disorder that usually begins before the age of 5 years. In most case...
Castleman Disease in the Parapharyngeal Space: A Case Report and Review of the Literature.
Castleman disease is most commonly found in the mediastinum, while the head and neck is the second most common location. The disease exists in a unicentric and multicentric variety and is usually succ...
A network perspective on unraveling the role of TRP channels in biology and disease.
Transient receptor potential (TRP) channels are a large family of non-selective cation channels that mediate numerous physiological and pathophysiological processes; however, still largely unknown are...
The association between cytotoxic T-lymphocyte associated antigen 4 (CTLA-4) exon-1 +49 A/G polymorphism and Hashimoto's thyroiditis (HT) has been widely studied. The results, however, are mixed. This...
Aortopulmonary collateral flow in cystic fibrosis assessed with phase-contrast MRI.
BACKGROUND: Cystic fibrosis (CF) is a common genetic disease in Caucasians. Chronic pulmonary disease with progressive destruction of the pulmonary parenchyma is two of the major morbidities, but the...
Patients with both chronic kidney disease (CKD) and diabetes mellitus (DM) are at increased risk for thrombotic events compared to those with one abnormality alone. Whether this can be attributed to c...
Primary Budd-Chiari syndrome in a 3-year-old boy with homozygous factor V Leiden G1691A mutation.
Budd-Chiari syndrome (BCS) is an uncommon disorder characterized by obstruction of hepatic venous outflow. The primary BCS is a rare disease with an incidence about 0.2 per million inhabitants per yea...
Secondary polycythemia with increased production of erythropoietin (EPO) is known to occur in kidney diseases such as hydronephrosis and cystic disease, but the mechanism remains unclear. We report an...
News Articles
Article examines global health policies and burden of disease on men
Men experience a higher burden of disease and lower life expectancy than women, but policies focusing on the health needs of men are notably absent from the strategies of global health organisations,...
AGA announces new grant to study relationship between gut microbiota, digestive disease
The AGA Research Foundation announced a new grant that intends to stimulate research into the relationship between the gut microbiota, one of today's most exciting areas of science, and digestive heal...
The Polycystic Liver: Webinar & Talk
Hamilton, Canada, May 18, 2013 --(PR.com)-- On May 26, the Hamilton Chapter of the PKD Foundation of Canada will host a webinar by Dr. Marie Hogan of the Mayo Clinic in Rochester, MN, followed by a t...
Flesh-eating disease victim gets prosthetic hands
(AP)—A woman who lost both hands, her left leg and right foot after contracting a flesh-eating disease has been fitted with prosthetic hands.
Dr. Allen J. Schultz now provides Laser Assisted New Attachment Procedure gum disease treatment to patients in San Juan Capistrano. The periodontist is fully authorized to perform the Laser Assisted N...
Most Americans Have Smoke-Free Rules For Home And Car
A national survey finds that a large majority of adults in the US voluntarily apply smoke-free rules in their homes or vehicles. Yet despite this, millions of Americans, many of them children, conti...
The good, the bad and the ugly — TFH cells in human health and disease
An increasing number of studies have highlighted novel aspects of the differentiation and function of T follicular helper (TFH) cells. Tangye et al. discuss these recent findings with a particular foc...
[AbbVie] pays for option to acquire [Alvine] equity or its celiac disease compound
In an effort to strengthen its existing gastroenterology pipeline, [Abbott]’s spin off [AbbVie Inc.] has paid $70mm up front for the exclusive option to acquire either equity in [Alvine Pharmaceutic...
Public offering nets $18.8mm for [Cyclacel]
[Cyclacel Pharmaceuticals Inc.] (mainly cancer therapies; also has projects for kidney disease, diabetes, and HIV/AIDS) netted $18.8mm through public offering of 6.67mm common shares at $3 each. Proce...
[Rockwell Medical] nets $38mm through FOPO
[Rockwell Medical Inc.] (end-stage renal and chronic kidney disease treatments) has netted $38mm through the follow-on public offering of 13.2mm common shares (including the overallotment) at $3.05. T...
Events
Diabetes: Secondary Complications, Regulation and Innovation Conference
SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.
Welcome to AgriGenomics World Congress 2013.
14th INTERNATIONAL CONFERENCE ON ALZHEIMER'S DRUG DISCOVERY
The annual Alzheimer's Drug Discovery Foundation (ADDF) conference brings together academic and industry scientists intent on accelerating the development of innovative treatments for Alzheimer’s di...
Companies
From its establishment in 1977, simply as a Distributor of diagnostic products, IDS has become a globally-recognised innovator and marketeer in the IVD industry.The Company is particularly well-known...
National Disease Research Interchange (NDRI)
Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...
Alvine Pharmaceuticals, Inc. is a private, clinical-stage, specialty biopharmaceutical company located in San Carlos, CA, focused on the development of biologics targeting autoimm...
Reverse Medical Corporation is a privately-held medical device company focused on expanding the endovascular management of acute stroke and neurovascular disease. The technology p...
PatientsLikeMe is a patient network that improves lives and a real-time research platform that advances medicine. Through the network, patients connect with others who have the sa...
Nimbus Discovery, a biotechnology company, harnesses cutting-edge computational technologies to uncover breakthroughs in small molecule pharmacology. Nimbus focuses on medically i...
VGTI Florida is the Florida-funded expansion of Oregon Health & Science University's highly successful Vaccine and Gene Therapy Institute. Research at the facility will focus on v...
The Apothecary Shops is one of the foremost chains of independent full-service pharmacies with specialties in veterinary medicine, infectious disease, oncology, ophthalmology, fer...
Tissue Regeneration Technologies, LLC
TRT is an international medical device company established to develop, manufacture and sell SoftWaveTM acoustical pressure pulse devices to treat various conditions poorly served...
Clinical Trials
The investigators hypothesize that a calcineurin inhibitor-free, steroid-free, co-stimulatory blockade-based immunosuppressive regimen, in combination with a GLP-1 agonist, will reduce the...
A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)
The main purpose of the study is to evaluate the efficacy and safety of the study drug known as prasugrel for the reduction of Vaso-Occlusive Crisis events in pediatric participants with s...
Ventricular Arrhythmias in Uremic Cardiomyopathy
There is a certain gene called sarcoplasmic reticulum gene (SERCA2a), which is found in heart muscle. This gene is also found in blood vessels and skin tissue. When active this gene builds...
Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of,...
An Efficacy and Safety Study of Galantamine for the Treatment of Patients With Alzheimer's Disease
The purpose of this study is to evaluate the efficacy and safety of two fixed doses (16mg/day and 24mg/day) of galantamine (a drug for treating dementia) versus placebo for the treatment o...
Intervention to Motivate Teens to be a Designated Organ Donor on Driver's License
This study will test the effectiveness of a multimedia campaign to educate ethnic minority teens about the choice to become a designated organ donor on their first driver's license.
A Study in Patients With Diabetic Kidney Disease
The purpose of this study is to determine if LY2382770 is safe and effective at protecting kidney function in patients with kidney disease due to diabetes.
RATIONALE: Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Interfe...
Parkinson's Disease Registry of the Muhammad Ali Parkinson Center
The purpose of the Parkinson’s disease Registry is to develop a national and international database of persons with Parkinson’s disease (PD). The Registry will be used to facilitate t...
D-Serine Adjuvant Treatment for Parkinson's Disease
The proposed experiment will evaluate the effects of the NMDA receptor full agonist D-serine (~2g/day) on persistent symptoms of Parkinson's Disease and on antiparkinsonian drugs-induced d...
Videos
Ultrasound image of Polycystic Kidney Disease (ADPKD)
Case and ultrasound by Simon van Hooland, nephrologist in AZ St Lucas, Ghent, Belgium This case demonstrates the US appearance of ADPKD (autosomal dominant p...
Medical and Biotech [MESH] Definitions
Casuistry
A method of ETHICAL ANALYSIS that emphasizes practical problem solving through examining individual cases that are considered to be representative; sometimes used to denote specious argument or rationalization. Differentiate from casuistics, which is the recording and study of cases and disease.
Incidental Findings
Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.
Insomnia, Fatal Familial
An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).
Wasting Disease, Chronic
A transmissible spongiform encephalopathy (prion disease) of DEER and elk characterized by chronic weight loss leading to death. It is thought to spread by direct contact between animals or through environmental contamination with the prion protein (PRIONS).
Ulmus
A plant genus of the family ULMACEAE that is susceptible to Dutch elm disease which is caused by the ASCOMYCOTA fungus, Ophiostoma.
