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Benign Ovarian Masses - Biotech, Pharma and Life Science Channel

23:49 EDT 18th June 2013 | BioPortfolio

PubMed Articles [ 4856 Associated PubMed Articles listed on BioPortfolio]

Genotype Misclassification in Genetic Association Studies of the rs1042522 TP53 (Arg72Pro) Polymorphism: A Systematic Review of Studies of Breast, Lung, Colorectal, Ovarian, and Endometrial Cancer.

Preferential loss of heterozygosity at the rs1042522 locus of the tumor protein 53 gene (TP53) (Arg72Pro) is observed in several tumors. Genetic association studies in oncology often use tumor tissue...

Limits to sustained energy intake. XVIII. Energy intake and reproductive output during lactation in Swiss mice raising small litters.

Limits to sustained energy intake (SusEI) during lactation in Swiss mice have been suggested to reflect the secretory capacity of the mammary glands. However, an alternative explanation is that milk p...

Limits to sustained energy intake. XVII. Lactation performance in MF1 mice is not programmed by fetal number during pregnancy.

Several studies have suggested that lactation performance may be programmed by the number of fetuses during pregnancy, whereas other studies indicate that processes during lactation are more important...

Limits to sustained energy intake. XV. Effects of wheel running on the energy budget during lactation.

The capacity of animals to dissipate heat may constrain sustained energy intake during lactation. We examined these constraints at peak lactation in MF1 mice that had ad libitum access to food, or tha...

Mutated PPP1R3B Is Recognized by T Cells Used To Treat a Melanoma Patient Who Experienced a Durable Complete Tumor Regression.

Adoptive cell therapy with tumor-infiltrating lymphocytes (TILs) represents an effective treatment for patients with metastatic melanoma. However, most of the Ag targets recognized by effective melano...

Interpreting raw biological mass spectra using isotopic mass-to-charge ratio and envelope fingerprinting.

Soft ionization, high-resolution mass spectrometry is widely used to characterize large biological molecules, such as proteins. Deconvolution ('deisotoping') of isotopic envelopes (iEs) in biological...

Reproductive Factors and Kidney Cancer Risk in 2 US Cohort Studies, 1993-2010.

Clinical and experimental findings suggest that female hormonal and reproductive factors could influence kidney cancer development. To evaluate this association, we conducted analyses in 2 large prosp...

Nicotine paradoxically affects the facilitatory effect of ovarian hormones on the adenosine receptor-mediated renal vasodilation.

We tested the hypothesis that nitric oxide synthase (NOS) and/or heme oxygenase (HO) modulate the hormonally-dependent nicotine interaction with adenosine receptor-mediated renal vasodilations. Vasodi...

Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells.

Viral infections of the ovary can cause pathological conditions. However, innate antiviral responses in the ovary are poorly understood. In this study, we demonstrate that Toll-like receptor 3 (TLR3),...

Association between race and follow-up diagnostic care after a positive prostate cancer screening test in the Prostate, Lung, Colorectal, and Ovarian cancer screening trial.

Follow-through of a positive screening test is necessary to reap the potential benefits of cancer screening. Racial variation in follow-through diagnostic care may underlie a proportion of the known d...

News Articles [ 1646 Associated News Articles listed on BioPortfolio]

'Cell' article reveals new resistance mechanism to chemotherapy in breast and ovarian cancer

It is estimated that between 5% and 10% of breast and ovarian cancers are familial in origin, which is to say that these tumours are attributable to inherited mutations from the parents in genes such...

New resistance mechanism to chemotherapy in breast and ovarian cancer

A new study explains why tumors with BRCA1 and BRCA2 mutations stop responding to PARP inhibitor drugs.

Colleen’s Dream Foundation Gifts $10,000 to The University of Arizona Cancer Center to Support Early Ovarian Cancer Detection Research

Colleen’s Dream Foundation has made a $10,000 gift to the University of Arizona Cancer Center in an effort to support early ovarian cancer detection research, according to Colleen’s Dream Foundati...

Tag Away

Skin tags (acrochordon) are benign growths, often raised on a pedicle with a tiny stem. 46% of the population has one or more of them.  They are usually ignored, but some people think they are ugly a...

NuView Life Sciences Announces Presentation of Data for Novel Prostate and Bladder Cancer Molecular Diagnostic at SNMMI

VPAC1-based Urine Screen Identified Shed Cancer Cells in 100% of Prostate and Bladder Cancer Patients and none of Healthy or Benign Prostate Hyperplasia Patients in Translational Research Study Park C...

The link between genes and cancer

(Medical Xpress)—When people think about genes and their relationship to cancer, most probably think about a person's hereditary cancer risk, especially after Angelina Jolie's recent news about her...

Scientists discover molecular pathway that can prevent death of oocytes due to chemotherapy

Young women who have cancer treatment often lose their fertility because chemotherapy and radiation can damage or kill their immature ovarian eggs, called oocytes. Now, Northwestern Medicine- scientis...

Book Targets Link Between Sedentary Lifestyle Such as That from Social Media Use, and Obesity

New York, NY, June 18, 2013 --(PR.com)-- Masses of people have been identified with obesity, and in recognizing the necessity of good well-being, there are ways to clear obesity through useful and re...

Colleen’s Dream Foundation Gifts $10,000 to The University of Arizona Cancer Center to Support Early Ovarian Cancer Detection Research

Phoenix, AZ (PRWEB) June 18, 2013 In an ongoing effort to support research for early detection of ovarian cancer, Colleen’s Dream Foundation has made a $10,000 gift to The University of Ariz...

An article in 'Cell' reveals a new resistance mechanism to chemotherapy in breast and ovarian cancer

(Centro Nacional de Investigaciones Oncologicas (CNIO)) The team led by Spanish National Cancer Research Centre researcher Óscar Fernández-Capetillo, head of the Genomic Instability Group, together...

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Companies [ 15 Associated Companies listed on BioPortfolio]

BSD Medical Corporation

BSD Medical Corporation develops, manufactures, markets and services systems to treat cancer and benign diseases using heat therapy delivered using focused radio frequency (RF) an...

Andover Wellness Group

Andover Wellness Group is a community-based organization that focuses on health and wellness by deploying the concept of preventive healthcare as its mantra. We passionately belie...

National Women’s Survivors Convention

Olympic medalist Shannon Miller, who between 1991 and 1996 became the United States’ most decorated gymnast ever with a combined 16 World Championships and Olympic med...

VG Life Sciences Inc.

San Marino, California-based VG Life Sciences Inc., formerly known as Viral Genetics, discovers and develops drug therapies from two exclusively licensed platform technologies bas...

Spirogen and BioAtla

Spirogen Limited (“Spirogen”) was founded in 2001 as a spin-out from several institutions including University College, London. Since that time, it has developed a novel...

IncellDx, Inc.

IncellDx, Inc. is a molecular diagnostics company dedicated to revolutionizing healthcare one cell at a time. By combining molecular diagnostics with high throughput cellular anal...

Urologix

Urologix, Inc., based in Minneapolis, MN develops, manufactures and markets minimally invasive medical products for the treatment of urological disorders. The Company has develope...

Urologix, Inc.

Urologix, Inc., based in Minneapolis, MN develops, manufactures and markets minimally invasive medical products for the treatment of urological disorders. The Company has develope...

Traversa Therapeutics

Traversa Therapeutics, Inc. (www.traversathera.com) is a San Diego, California-based biopharmaceutical company engaged in the discovery, development and commercialization of RNAi...

Provista Diagnostics, Inc.

Provista Diagnostics, Inc., a Delaware company, develops and commercializes breakthrough, easy to administer blood-based diagnostic tests for early oncology-related disease state...

Clinical Trials [ 997 Associated Clinical Trials listed on BioPortfolio]

S0230 Goserelin in Preventing Ovarian Failure in Women Receiving Chemotherapy for Breast Cancer

RATIONALE: Goserelin blocks hormone production in the ovaries. It is not yet known whether ovarian suppression using goserelin will prevent ovarian failure (early menopause) in women recei...

Vorinostat, Carboplatin and Gemcitabine Plus Vorinostat Maintenance in Women With Recurrent, Platinum-Sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

The purpose of this research study is to: 1) Determine the highest dose of the drug vorinostat that can be given safely in combination with carboplatin and gemcitabine and 2) determine how...

An Observational Study of YONDELIS®+PLD for the Treatment of Patients With Platinum-sensitive Relapse of Ovarian Cancer

Clinical trials are, due to the inclusion and exclusion criteria, accomplished with defined patient groups, which are not representative for the whole patient population. Especially elder...

Optimal rhCG(Ovidrel®) Dose in Poor Responder During IVF and ICSI Cycles

Choriogonadotropin alfa (Ovidrel®) is a recombinant hCG (rhCG) preparation derived from genetically engineered Chinese hamster ovary cells, which is widely used for final oocyte maturatio...

Docetaxel and Carboplatin in Treating Patients With Relapsed Stage III or Stage IV Ovarian Epithelial or Primary Peritoneal Cavity Cancer

RATIONALE: Drugs used in chemotherapy, such as docetaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from div...

Gemcitabine and Topotecan in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer

RATIONALE: Drugs used in chemotherapy, such as gemcitabine and topotecan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from div...

Erlotinib, Docetaxel, and Carboplatin in Treating Patients With Newly Diagnosed Stage III or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer

RATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as docetaxel and carboplatin, work in diffe...

Phase II Clinical Study of Pegylated Liposomal Doxorubicin Hydrochloride Injection as 2nd-line or Later Therapy in Patients With Mullerian Carcinoma (Epithelial Ovarian Carcinoma, Primary Carcinoma of Fallopian Tube, Peritoneal Carcinoma) Having Prior Pla

The purpose of this study is to assess the effectiveness and safety of pegylated liposomal doxorubicin hydrochloride injection in Japanese patients with Mullerian carcinoma. This clinical...

Imatinib Mesylate in Combination With Docetaxel for Advanced, Platinum-Refractory Ovarian Cancer

Imatinib mesylate is an inhibitor of the receptor tyrosine kinases for platelet-derived growth factor (PDGF) and stem cell factor (SCF), c-Kit, and inhibits PDGF- and SCF-mediated cellular...

Ixabepilone and Liposomal Doxorubicin in Treating Women With Advanced Ovarian Epithelial, Peritoneal Cavity, or Fallopian Tube Cancer or Metastatic Breast Cancer

RATIONALE: Drugs used in chemotherapy, such as ixabepilone and liposomal doxorubicin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping t...

Medical and Biotech [MESH] Definitions

Luteinization

Formation of CORPUS LUTEUM. This process includes capillary invasion of the ruptured OVARIAN FOLLICLE, hypertrophy of the GRANULOSA CELLS and the THECA CELLS, and the production of PROGESTERONE. Luteinization is regulated by LUTEINIZING HORMONE.

Mastocytoma

A solid tumor consisting of a dense infiltration of MAST CELLS. It is generally benign.

Ultrasound, High-intensity Focused, Transrectal

Tissue ablation of the PROSTATE performed by ultrasound from a transducer placed in the RECTUM. The procedure is used to treat prostate cancer (PROSTATIC NEOPLASMS) and benign prostatic hypertrophy (PROSTATIC HYPERPLASIA).

Endometrial Stromal Tumors

Neoplasms of the endometrial stroma that sometimes involve the MYOMETRIUM. These tumors contain cells that may closely or remotely resemble the normal stromal cells. Endometrial stromal neoplasms are divided into three categories: (1) benign stromal nodules; (2) low-grade stromal sarcoma, or endolymphatic stromal myosis; and (3) malignant endometrial stromal sarcoma (SARCOMA, ENDOMETRIAL STROMAL).

Follicle Stimulating Hormone, Human

A major gonadotropin secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and the LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. The alpha subunit is common in the three human pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.

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