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Biopharmaceuticals - news, views, blogs and reports - Biotech, Pharma and Life Science Channel

12:15 EDT 21st May 2013 | BioPortfolio

Biopharmaceuticals are medical drugs (see pharmacology) produced using biotechnology. They include proteins (including antibodies), nucleic acids (DNA, RNA or antisense oligonucleotides) and living microorganisms like virus and bacteria where the virulance of viruses and bacteria is reduced by the process of atenuation, they can be used for therapeutic or in vivo diagnostic purposes, and are produced by means other than direct extraction from a native (non-engineered) biological source.

Classification of biopharmaceuticals

Blood factors (Factor VIII and Factor IX)
Thrombolytic agents (tissue plasminogen activator)
Hormones (insulin, glucagon, growth hormone, gonadotrophins)
Haematopoietic growth factors (Erythropoietin, colony stimulating factors)
Interferons (Interferons-α, -β, -γ)
Interleukin-based products (Interleukin-2)
Vaccines (Hepatitis B surface antigen)
Monoclonal antibodies (Various)
Additional products (tumour necrosis factor, therapeutic enzymes)

Uses

Erythropoietin - Treatment of anaemia
Interferon-α - Treatment of leukaemia
Interferon-β - Treatment of multiple sclerosis
Monoclonal antibody - Treatment of rheumatoid arthritis
Colony stimulating factors - Treatment of neutropenia
Glucocerebrosidase - Treatment of Gaucher's disease

Source: Wikipedia

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News Articles [ 839 Associated News Articles listed on BioPortfolio]

Multiple Target ALS Drug Ready for Genervon's Phase 2 Trial

Multiple targets, highly effective, breakthrough therapy for ALS sufferers may now be within reach. Winston Ko, the CEO of Genervon Biopharmaceuticals, will be presenting on Frida...

Rexahn Pharmaceuticals To Present At The Second Annual Marcum LLP MicroCap Conference

ROCKVILLE, Md., May 20, 2013 /PRNewswire/ -- Rexahn Pharmaceuticals, Inc. (NYSE MKT: RNN), a clinical stage biopharmaceutical company developing potential best-in-class oncology therapies announc...

GE Healthcare Launches #GetFit Cancer Prevention Campaign

Challenges the World to Form Healthy Habits GE Healthcare has today launched its third annual #GetFit (www.ge-getfit.com) global public awareness campaign on cancer prevention...

Puma Biotechnology Comment on Trading Activity

Puma Biotechnology, Inc. (NYSE: PBYI), a development stage biopharmaceutical company, has been contacted by the New York Stock Exchange regarding today’s trading in the Company...

Biopharmaceutical Equipment and Technology Assets of Palo Alto, CA Campus of Pharmaceutical Developer Affymax to be Auctioned by Heritage Global Partners and Maynards June 13-14

Heritage Global Partners (“HGP”), a global leader in asset advisory and auction services and a wholly owned subsidiary of Counsel RB Capital (OTCQB: CRBN), in conjuncti...

Tetraphase Pharmaceuticals to Present at the Annual UBS Global Healthcare Conference

Tetraphase Pharmaceuticals, Inc. (NASDAQ: TTPH), a clinical-stage biopharmaceutical company developing a portfolio of potent new antibiotics designed to be effective against dange...

Actinium Pharmaceuticals Clinical Results to be Presented at 8th International Symposium on Targeted Alpha Therapy Conference

NEW YORK, May 16, 2013 /PRNewswire/ -- Actinium Pharmaceuticals, Inc. (OTCBB: ATNM), a biopharmaceutical company that develops innovative targeted payload immunotherapeutics for treatment of adva...

Access Pharmaceuticals Reports First Quarter Results

DALLAS and NEW YORK, May 16, 2013 /PRNewswire/ -- ACCESS PHARMACEUTICALS, INC. (OTCBB: ACCP), an emerging biopharmaceutical company, released its first quarter ended March 31, 2013 financial resu...

Nordion Signs Contract Manufacturing Agreement with Navidea Biopharmaceuticals

Nordion Inc. (TSX: NDN) (NYSE: NDZ), a leading provider of products and services to the global health science market, today announced it has signed a contract manufacturing agreem...

Navidea Biopharmaceuticals Signs Manufacturing and Supply Agreement with Nordion

– Nordion to Produce and Distribute Supplies of 123I-labeled Drug Product NAV5001 for Late-Phase Clinical Trials – Navidea Biopharmaceuticals, Inc. (NYSE MKT: NAVB), a bio...

Events [ 1 Associated Events listed on BioPortfolio]

7th Lyophilization Americas Conference

Achieving optimum lyophilization processes

Companies [ 223 Associated Companies listed on BioPortfolio]

AstraZeneca

AstraZeneca is a global, innovation-driven biopharmaceutical business with a primary focus on the discovery, development and commercialization of prescription medicines. As a leader in gastrointestin...

Pi2 Solutions Ltd

Established in 2002 by its founding directors, Nigel Johnson and Mark Drinkwater to address the information and literature management needs of biopharmaceutical companies.  Global leader in its...

Quintiles

Quintiles is the only fully integrated biopharmaceutical services company offering clinical, commercial, consulting and capital solutions worldwide. The Quintiles network of mo...

Tokai Pharmaceuticals

Tokai Pharmaceuticals is a U.S. biopharmaceutical company focused on developing new treatments for prostate cancer. The company’s lead drug candidate, TOK-001, is the first i...

Alvine Pharmaceuticals, Inc.

Alvine Pharmaceuticals, Inc. is a private, clinical-stage, specialty biopharmaceutical company located in San Carlos, CA, focused on the development of biologics targeting autoimm...

Xenetic Biosciences plc

Xenetic is a leading UK-based biopharmaceutical company providing leading-edge expertise in the development of a whole new generation of drugs and vaccines. Working with some of the largest pharma...

Puma Biotechnology, Inc.

Puma Biotechnology, Inc. is a development stage biopharmaceutical company that acquires and develops innovative products for the treatment of various forms of cancer. The Company...

Verastem, Inc.

Verastem, Inc. is a private biopharmaceutical company focused on discovering and developing novel drugs that selectively target cancer stem cells. Cancer stem cells are an underly...

Clovis Oncology, Inc.

Clovis Oncology, Inc. is a biopharmaceutical company focused on acquiring, developing and commercializing innovative anti-cancer agents in the U.S., Europe and additional international markets. Clovis...

Kamada, Ltd.

Kamada is a public biopharmaceutical company (TASE: KMDA) developing, producing and marketing a line of specialty life-saving biopharmaceuticals. Licensed and marketed worldwide,...

Clinical Trials [ 2 Associated Clinical Trials listed on BioPortfolio]

Nicotine Vaccination and Nicotinic Receptor Occupancy

This is a molecular imaging research study designed to examine how much nicotine gets into the brain before and after vaccination with NicVAX, a nicotine vaccine developed by Nabi Biopharm...

Juvista in the Non-surgical Improvement of Existing Scars

Renovo, a Biopharmaceutical company involved in the development of drugs to improve the appearance of scars and enhance wound healing, are proposing to carry out research in improving the...

PubMed Articles [ 340 Associated PubMed Articles listed on BioPortfolio]

Antioxidant and anti-inflammatory activities of the phenolic extracts of Sapium sebiferum (L.) Roxb. leaves.

The leaves of Sapium sebiferum have long been used in Traditional Chinese Medicine (TCM) for the treatment of eczema, shingles, edema, swelling, ascites, scabs, and snakebites, among other maladies.

Synthesis and Biopharmaceutical Studies of JLTN as Potential Dasatinib Prodrug.

Dasatinib was identified as a potent orally administered Src/Abl kinase inhibitor with excellent antiproliferative activity against Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia in chr...

Coupled solid phase extraction and microparticle-based stability and purity-indicating immunosensor for the determination of recombinant human myelin basic protein in transgenic milk.

An optical immunosensor was developed and validated on the surface of microparticles for the determination of a biopharmaceutical protein. The recombinant human myelin basic protein (rhMBP) was produc...

Multifunctional nanocomposites of lanthanide (Eu(3+), Tb(3+)) complexes functionalized magnetic mesoporous silica nanospheres covalently bonded with polymer modified ZnO.

Methacrylic-group-modified ZnO nanoparticles (designated ZnO-MAA) prepared through the sol-gel process are copolymerized with 2-hydroxyethyl methacrylate (HEMA) to form ZnO-MAA-PHEMA hybrid system. Zn...

Dissolution enhancement of Deflazacort using hollow crystals prepared by antisolvent crystallization process.

Deflazacort (DFZ), a derivate of prednisolone, is a poorly soluble drug which has been proposed to have major advantages over other corticosteroids. Poorly soluble drugs present limited bioavailabilit...

Technological and biopharmaceutical optimization of nystatin release from a multiparticulate based bioadhesive drug delivery system.

Formulation considerations of a new drug delivery system include controlling the site of release of the active ingredient, maintaining drug level for a suitable time and decreasing dosage frequency. I...

Differential surface properties of commercial crystalline telmisartan samples.

The aim of the present study was to investigate differences in surface chemistry of commercially available telmisartan (TMS) samples in Indian market and to correlate them to the surface molecular env...

Joint EMA, ISBS, and DR-IBS International Symposium on Biopharmaceutical Statistics: Bridging drug development from research to marketing.

Establishment of a mammalian cell line suitable for industrial production of recombinant protein using mutations induced by high-energy beam radiation.

Mammalian cells are extensively used for production of biopharmaceuticals. Most cells used in industry have infinite proliferative capacity, which provides a high number of cells and corresponding pro...

Evolving Approaches to Metastatic Breast Cancer Patients Pre-treated with Anthracycline and Taxane.

Metastatic breast cancer is currently incurable and the goals of therapy focus on prolonging survival and maintaining quality of life by controlling symptoms and minimizing toxicity. Treatments for me...

Medical and Biotech [MESH] Definitions

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