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Botulinum Toxin A Merz - Biotech, Pharma and Life Science Channel

08:35 EDT 30th March 2017 | BioPortfolio

PubMed Articles [607 Associated PubMed Articles listed on BioPortfolio]

Clostridium perfringens Type A Isolates of Animal Origin with Decreased Susceptibility to Metronidazole Show Extensive Genetic Diversity.

Metronidazole is a first-line drug for the treatment of human infections caused by anaerobic bacteria. Although most Clostridium perfringens isolates are susceptible to metronidazole, a number of stra...

A genetic switch controls the production of flagella and toxins in Clostridium difficile.

In the human intestinal pathogen Clostridium difficile, flagella promote adherence to intestinal epithelial cells. Flagellar gene expression also indirectly impacts production of the glucosylating tox...

Reactions with Antisera and Pathological Effects of Staphylococcus aureus Gamma-Toxin in the Cornea.

This study analyzed the toxicity of purified gamma-toxin from Staphylococcus aureus and the protectiveness of antisera to gamma-toxin in the rabbit cornea.

Hemolysis, Elevated Liver Enzymes, Low Platelets Syndrome Superimposed on Hemolytic Uremic Syndrome.

A pregnancy complicated by typical hemolytic uremic syndrome (HUS) and hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome is reported. At 20 weeks of gestation, a case of HUS was diagno...

Comparative Study of Xenobiotic-Free Media for the Cultivation of Human Limbal Epithelial Stem/Progenitor Cells.

The culture of human limbal epithelial stem/progenitor cells (LSCs) in the presence of animal components poses the risk of cross-species contamination in clinical applications. We quantitatively compa...

Elongated and shortened peptidomimetic inhibitors of the proprotein convertase furin.

Novel elongated and shortened derivatives of the peptidomimetic furin inhibitor phenylacteyl-Arg-Val-Arg-4-amidinobenzylamide were synthesized. The most potent compounds, e.g., Nα(carbamidoyl)Arg-Arg...

The Role of Peganum harmala Ethanolic Extract and Type II Toxin Antitoxin System in Biofilm Formation.

Toxin antitoxin system is a regulatory system that antitoxin inhibits the toxin. We aimed to determine the role of TA loci in biofilm formation in K. pneumoniae clinical and environmental isolates; al...

A Vibrio cholerae autoinducer-receptor pair that controls biofilm formation.

Quorum sensing (QS) is a cell-cell communication process that enables bacteria to track cell population density and orchestrate collective behaviors. QS relies on the production and detection of, and ...

Diphtheria toxin-based anti-human CD19 immunotoxin for targeting human CD19(+) tumors.

CD19 is expressed on normal and neoplastic B cells and is a promising target for immunotherapy. However, there is still an unmet need to further develop novel therapeutic drugs for the treatment of th...

F199E substitution reduced toxicity of Clostridium perfringens epsilon toxin by depriving the receptor binding capability.

Epsilon toxin (ETX), a potent toxin, is produced by types B and D strains of Clostridium perfringens, which could cause severe diseases in humans and domestic animals. Mutant rETX(F199E) was previousl...

News Articles [206 Associated News Articles listed on BioPortfolio]

Ultherapy® and Cellfina® System Recognized as Best-in-Class Treatments in NewBeauty’s Annual Beauty Choice Awards

Merz Aesthetics, a division of Merz North America, announced today that Ultherapy® and the Cellfina® System have been recognized by NewBeauty readers and editors in their 2017 B...

Merz Pharma GmbH Co KgaA Pharmaceuticals Healthcare Deals and Alliances Profile [Updated: 17022017] Prices from USD $250

SummaryMerz Pharma GmbH Co KgaA Merz Pharma, a subsidiary of Merz GmbH Co. KGaA is a pharmaceutical company that specializes in the development of products for aesthetic and medical dermatology and ...

Merz Outsources its Compound Management to BioAscent

BioAscent supplies screening plates on demand to provide flexible and cost-effective management of solid and liquid compounds BioAscent Discovery and Merz Pharmaceuticals GmbH, part of the Merz Pharma...

Bezlotoxumab for Recurrent C difficile Infections

A single intravenous dose of bezlotoxumab in combination with standard-of-care antibiotic treatment for primary or recurrent Clostridium difficile infection was associated with a 38% lower rate of rec...

Research from Dr. Song 3D Urology and Prostate Clinic Finds Links Between Toxins C3a and Prostatic Hyperplasia in Tissue Inflammation

Dr.Songxinping Lab finds C3a to play a large role in urinary track issues regardless of age, and weight. Their 3D Prostate Targeted Treatment is based on the research. (PRWEB) March 27, 2017 The 3D ...

Threshold Pharmaceuticals to Combine with Molecular Templates

NewsMolecular Templates' proprietary technology has been used to create a new class of biologic drug candidates known as Engineered Toxin Bodies or ETBs.

Will life-saving benefits of toxin-blocking biotech corn help win over skeptics of genetic engineering?

Aflatoxin is a well-known global health threat. This poison, produced by the Aspergillus fungus, is common in corn, wheat, rice and many other crops. Hot climates and inadequate storage practices aug...

Will toxin-blocking biotech corn help win over skeptics of genetic engineering?

Aflatoxin is a well-known global health threat. This poison, produced by the Aspergillus fungus, is common in corn, wheat, rice and many other crops. Hot climates and inadequate storage practices aug...

2016 Was Not a Good Year for New FDA Anti-infectives

In 2016, two anti-hepatitis C virus combination drugs were approved, as were monoclonal antibodies directed at bacterial toxins (anthrax toxin and Clostridium difficile toxin B), as well as an oral ch...

Revance Therapeutics Inc RVNC Financial and Strategic SWOT Analysis Review [Updated: 13012017] Prices from USD $300

SummaryRevance Therapeutics Inc Revance is a biopharmaceutical company that develops, manufactures and commercializes novel botulinum toxin products. The company's products comprise RT001, a physician...

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Companies [12 Associated Companies listed on BioPortfolio]

Merz Pharmaceuticals

Merz Pharmaceuticals, LLC is a part of Merz, Inc., a wholly owned U.S. subsidiary of the Merz Group of Companies and was established in 1995 to develop and commercialize products for the Merz Group. ...

Merz Pharma GmbH & Co. KGaA

Merz Neurosciences

Merz Neurosciences is a division of Merz North America, a specialty healthcare company that develops and commercializes treatment solutions in aesthetics, dermatology and neurosci...

Merz Inc.

Pharmaleads

Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...

OCuSOFT, Inc.

OCuSOFT, Inc. is a privately-held Richmond, TX USA-based ophthalmic research, development and supply company with an established reputation for innovation, particularly in the are...

Merz North America, Inc.

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in medical and aesthetic dermatology, and neurology in the U.S...

Merz North America

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in aesthetics, dermatology and neurology in the U.S. and Canad...

Merz, Inc.

Merz, Inc. is a focused specialty healthcare company that is responsible for developing and commercializing innovative products and solutions in neurology, medical aesthetics, and...

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

Clinical Trials [339 Associated Clinical Trials listed on BioPortfolio]

Sensorimotor Mapping in Patients With Writer's Cramp

Writer's cramp (WC) is a form of focal dystonia, a movement disorder characterized by sustained or intermittent muscle contractions causing abnormal, often repetitive movements, postures, ...

Feasibility Pilot for the ReBOO-trial

This is a pilot testing the feasibility of the 'REpurposing BOtulinum Toxin in Treatment of Obesity in Adolescents' trial (ReBOO-trial). The full-scale ReBOO will further investigate safet...

A Study of the Efficacy of Botox in the Treatment of Social Anxiety Disorder

The goal of this study is to see whether Botox is an effective treatment for social anxiety disorder (SAD). Participants will complete two short surveys on depression and anxiety symptoms,...

Comparative Study Suburothelial and Trigonal Botulinum Toxin A Injection in Treatment of Interstitial Cystitis

There is no consensus of the therapeutic efficacy and safety between suburothelial injection and trigonal injection of botulinum toxin A (BoNT-A) in treatment of interstitial cystitis/blad...

Investigating Typhoid Fever Pathogenesis

Typhoid fever results from infection with a bacterium called Salmonella Typhi and is a major cause of illness worldwide. It is estimated to infect 20-25 million people every year and can a...

Botulinum Toxin Type A Block of the Otic Ganglion in Chronic Cluster Headache: Safety Issues

Cluster headache (CH) is the most common of the trigeminal autonomic cephalalgias and one of the most severe pains known to man, having a large impact on the sufferer's quality of life. A ...

Effect of Botulinum Toxin A on Neurogenic Detrusor Overactivity in Chronic Spinal Cord Injured Patients

This study investigated the changes in urothelial dysfunction and sensory protein expression in the bladder urothelium with time after onabotulinumtoxin injection in spinal cord injured (S...

Myocardial Injury and Severe Pneumococcal Pneumonia

Hypothesis: The "novo" cardiovascular events (CVE)in patients with severe community-acquired pneumonia (CAP) are frequent (17%) and could be associated with both direct pneumococcal myocar...

Effectiveness of Onabotulinumtoxin A (Botox) in Pediatric Patients Experiencing Migraines: A Study in the Pediatric Pain Population

The purpose of the research is to examine the outcomes of pediatric patients receiving Botulinum toxin type A (Botox ®) for the treatment of migraine. There is limited literature on the e...

Therapeutic Effect of Botulinum Toxin A for the Treatment of Plantar Fasciitis.

Plantar fasciitis is the most common cause of plantar heel pain and is commonly present in people 40 years of age or older, overweight, sedentary or with intense physical activity. It is c...

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Medical and Biotech [MESH] Definitions

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.

Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.

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