Botulinum Toxin A Merz - Biotech, Pharma and Life Science Channel

09:23 EST 27th January 2015 | BioPortfolio

PubMed Articles [669 Associated PubMed Articles listed on BioPortfolio]

Assessment of T-2 toxin effect and its metabolite HT-2 toxin combined with insulin-like growth factor I, leptin and ghrelin on progesterone secretion by rabbit ovarian fragments.

Assessment of A-trichothecene mycotoxins (T-2 and HT-2 toxins) effect combined with growth factor IGF-I, and the metabolic hormones leptin and ghrelin on progesterone secretion by rabbit ovarian fragm...

Evaluation of the BD Max Cdiff assay for the detection of toxigenic Clostridium difficile in human stool specimens.

The Becton Dickinson (BD) PCR-based GeneOhm Cdiff assay has demonstrated a high sensitivity and specificity for detecting Clostridium difficile. Recently, the BD Max platform, using the same principle...

Staphylococcus aureus ST6-t701 Isolates from Food Poisoning Outbreaks (2006-2013) in Xi'an, China.

The aim of the study was to investigate the molecular epidemiologic of Staphylococcus aureus isolated from seven staphylococcal food poisoning (SFP) outbreaks between 2006 and 2013 in Xi'an, northwest...

An Autonomous In Vivo Dual Selection Protocol for Boolean Genetic Circuits.

Success in synthetic biology depends on the efficient construction of robust genetic circuitry. However, even the direct engineering of the simplest genetic elements (switches, logic gates) is a chall...

Recoded organisms engineered to depend on synthetic amino acids.

Genetically modified organisms (GMOs) are increasingly used in research and industrial systems to produce high-value pharmaceuticals, fuels and chemicals. Genetic isolation and intrinsic biocontainmen...

The role of Dorsomedial Hypotalamus ionotropic glutamate receptors in the hypertensive and tachycardic responses evoked by Tityustoxin intracerebroventricular injection.

The scorpion envenoming syndrome is an important worldwide public health problem due to its high incidence and potential severity of symptoms. Some studies address the high sensitivity of the central ...

Physiological behaviour of gliotoxigenic Aspergillus fumigatus sensu stricto isolated from maize silage under simulated environmental conditions.

Environmental conditions play a key role in fungal development. During the silage production process, humidity, oxygen availability and pH vary among lactic-fermentation phases and among different sil...

The effects of lead sources on oral bioaccessibility in soil and implications for contaminated land risk management.

Lead (Pb) is a non-threshold toxin capable of inducing toxic effects at any blood level but availability of soil screening criteria for assessing potential health risks is limited. The oral bioaccessi...

Risk factors, outcomes, and epidemiology associated with Clostridium difficile infection in patients with hematologic malignancies in a tertiary care hospital in China.

Purpose: To evaluate the risk factors, outcomes, and epidemiology associated with Clostridium difficile infection (CDI) in patients with hematologic malignancies in a tertiary care hospital in China. ...

Conophylline protects cells in cellular models of neurodegenerative diseases by inducing mTOR-independent autophagy.

Macroautophagy is a cellular response that leads to the bulk, non-specific degradation of cytosolic components, including organelles. In recent years, it has been recognized that autophagy is essentia...

News Articles [209 Associated News Articles listed on BioPortfolio]

ALPHAEON Begins Phase III Study For Its Neurotoxin, EVOSYAL

IRVINE, Calif., Jan. 22, 2015 /PRNewswire/ --  ALPHAEON® Corporation announced today that the U.S. Food and Drug Administration (FDA) agreed to the protocol for its phase III clinical study ...

Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens

Unprecedented speed and accuracy for detection of STECs adulterants is now part of the CDx product line. Boulder, CO / Rootstown, OH (PRWEB) January 22, 2015 Crystal Diagnostics (CDx) Xpress System, ...

Luminex xMAP® Tracks 6 of the Most Dangerous Biotoxins

AUSTIN, Texas, Jan. 21, 2015 /PRNewswire/ -- Quickly detecting and identifying dangerous biotoxins is now a reality, thanks to the xMAP® Biothreat Toxin Panel (BTP) by Luminex. The xMAP...

Tetrodotoxin Poisoning Outbreak From Imported Puffer Fish

Preparation and consumption of puffer fish is safe only with specialized training, as they contain a highly lethal toxin. What was the source in this outbreak? Morbidity & Mortality Weekly Report

NY State to Expand Fluoridation Ignoring Own Evidence of Harm & Ineffectiveness

NEW YORK, Jan. 20, 2015 /PRNewswire-USNewswire/ -- Despite their own evidence of harm and ineffectiveness, New York State unelected bureaucrats encourage water fluoridation expansion thr...

Recoded organisms engineered to depend on synthetic amino acids

Genetically modified organisms (GMOs) are increasingly used in research and industrial systems to produce high-value pharmaceuticals, fuels and chemicals. Genetic isolation and intrinsic biocontainmen...

Transgenic Crops: Multiple Toxins Not a Panacea for Pest Control

A new study by scientists at the University of Arizona, United States, says strategies for delaying insect resistance to transgenic crops relies on assumptions that are often overly optimistic. Crops ...

Optimizing pyramided transgenic Bt crops for sustainable pest management

This analytic Review of data from 38 field studies identifies key factors affecting the durability of Bt toxin pyramids, and should inform future resistance management strategies.

Los Angeles Law Firm Bailey & Partners Warns of Carbon Monoxide's Insidious Danger

Every year, especially in the winter, carbon monoxide poisoning causes hundreds of deaths and thousands of hospitalizations. Bailey & Partners comments on recent carbon monoxide poisoning cases an...

Affinity Life Sciences to Produce Lyophilized Chem-Bio Assays for SRC Acumen

Amherst, NH, January 16, 2015 --(PR.com)-- Affinity Life Sciences, Inc. and SRC Acumen, LLC are announcing the continued production of freeze-dried qPCR and toxin assays. As part of this agreement, A...

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Companies [7 Associated Companies listed on BioPortfolio]

Merz North America, Inc.

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in medical and aesthetic dermatology, and neurology in the U.S...

Merz North America

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in aesthetics, dermatology and neurology in the U.S. and Canad...

Merz, Inc.

Merz, Inc. is a focused specialty healthcare company that is responsible for developing and commercializing innovative products and solutions in neurology, medical aesthetics, and...

Pharmaleads

Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

Merz Aesthetics

Merz Aesthetics, the new business unit of Merz Pharma Group, is a leader in the global aesthetic medicine market. With a 100-year history of compassion and innovation in healthcare, Merz Aesthetics i...

DentaSpa

DentaSpa™ is one of the nation’s leading Botulinum Toxin, dermal fillers and injectables business education companies tailored exclusively for dental practitioners. Dent...

Clinical Trials [215 Associated Clinical Trials listed on BioPortfolio]

Botulinum Toxin A to Treat Arm Tremor

The objective of this study is to assess the efficacy and safety of a single, kinematic-analysis-based intramuscular injection of NT 201, compared with placebo, in moderate to marked essen...

Safety of Sublingual dmLT for ETEC

A Phase 1 dose escalating study of ETEC candidate vaccine to determine safety and immunogenicity of a multi-dose regimen in healthy adult volunteers. The study will be conducted at Cincinn...

Dysport® Adult Upper Limb Spasticity Extension Study

The purpose of this research study is to assess the long term safety of Dysport in hemiparetic subjects with upper limb spasticity due to stroke or traumatic brain injury over repeated tre...

Safety and Efficacy Study of Botulinum Toxin for the Treatment of Glabellar Frown Lines

The primary objective of the study is to evaluate the efficacy in wrinkle reduction of a single treatment of three different doses of botulinum toxin compared to placebo, in the treatment ...

Intravesicular Onabotulinumtoxin A in Interstitial Cystitis

The purpose of this research study is to identify the optimal usage of Onabotulinumtoxin A in interstitial cystitis. Onabotulinumtoxin A, more commonly known by the trade name Botox®, is ...

Arm Spasticity - Non-Interventional Study Early BIRD (BoNT Treatment: Initial and Repeated Documentation) [AS-NIS Early BIRD]

Botulinum toxin A (BoNT-A) is effective and safe in alleviating post-stroke spasticity and reducing the burden of associated symptoms. The hypothesis for this non-interventional study in ...

Incobotulinum Toxin A (Xeomin®) As A Treatment For Focal Task-Specific Dystonia Of The Musician's Hand

The investigational drug being studied in this protocol is Incobotulinumtoxin A (Xeomin®). Botulinum toxin (BoNT) prevents the release of the acetylcholine from peripheral nerves, inhibit...

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

Background: - Researchers who are studying hairy cell leukemia, and how the disease compares with other disorders, are interested in obtaining additional samples from leukemia patients an...

Botox Injection in Treatment of Chronic Migraine

Chronic migraine is in many cases a most disabling condition. Chronic migraine is defined as headaches for at least 15 days per month, of which 8 days have typical migraine features. In ma...

BOTOX® Treatment in Pediatric Upper Limb Spasticity

This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) in pediatric patients with upper limb spasticity.

Medical and Biotech [MESH] Definitions

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.

Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.

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