Botulinum Toxin A Merz - Biotech, Pharma and Life Science Channel

07:47 EST 4th March 2015 | BioPortfolio

PubMed Articles [682 Associated PubMed Articles listed on BioPortfolio]

Comparison between quantitative X-ray imaging, dual energy X-ray absorptiometry and microCT in the assessment of bone mineral density in disuse-induced bone loss.

Objectives: We recently introduced a new methodology called quantitative X-ray imaging (qXRI) to investigate bone mineral density in isolated rodent bones. The aims of the present study were to compar...

Assessment of the effectiveness and safety of Sativex ® in compassionate use.

INTRODUCTION. Sativex ® is a drug approved for use in the treatment of spasticity in multiple sclerosis. We sought to study the tolerability and effectiveness of this drug product in pathologies beyo...

Presence and Correlation of Some Enteric Indicator Bacteria, Diarrheagenic Escherichia coli Pathotypes, and Salmonella Serotypes in Alfalfa Sprouts from Local Retail Markets in Pachuca, Mexico.

Data on the presence of diarrheagenic Escherichia coli pathotypes (DEPs) in alfalfa sprouts and correlations between the presence of coliform bacteria (CB), fecal coliforms (FC), E. coli, DEPs, and Sa...

Antimicrobial Interventions for O157:H7 and Non-O157 Shiga Toxin-Producing Escherichia coli on Beef Subprimal and Mechanically Tenderized Steaks.

Non-O157 Shiga toxin-producing Escherichia coli (STEC) is an emerging risk for food safety. Although numerous postharvest antimicrobial interventions have been effectively used to control E. coli O157...

Efficacy of Antimicrobial Compounds on Surface Decontamination of Seven Shiga Toxin-Producing Escherichia coli and Salmonella Inoculated onto Fresh Beef.

Several antimicrobial compounds have been used in commercial meat processing plants for decontamination of pathogens on beef carcasses, but there are many commercially available, novel antimicrobial c...

The efficacy and safety of liquid-type botulinum toxin type a for the management of moderate to severe glabellar frown lines.

Botulinum toxin type A has been widely used to correct unwanted hyperfunctional facial lines. Most forms of botulinum toxin type A currently used require reconstitution, which is very inconvenient for...

High turnover of Tissue Factor enables efficient intracellular delivery of antibody-drug conjugates.

Antibody drug conjugates (ADC) are emerging as powerful cancer treatments that combine antibody-mediated tumor targeting with the potent cytotoxic activity of toxins. We recently reported the developm...

Safety and Efficacy of Botulinum Toxin A in Children Undergoing Lower Limb Lengthening and Deformity Correction: Results of a Double-blind, Multicenter, Randomized Controlled Trial.

Lengthening of the lower limb is a complex procedure in which pain management and complications such as pin-site infections and muscle contractures impact the family and affect the child's quality of ...

A Novel Mechanism of Bacterial Toxin Transfer within Host Blood Cell-Derived Microvesicles.

Shiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli, which are non-invasive strains that can lead to hemolytic uremic syndrome (HUS), associated with renal failure and...

Safety and immunogenicity of an investigational 4-component Staphylococcus aureus vaccine with or without AS03B adjuvant: Results of a randomized phase I trial.

We assessed the safety, reactogenicity and immunogenicity of a staphylococcal vaccine combining capsular polysaccharides types 5 and 8 (CPS5/8), conjugated to tetanus toxoid (TT), with mutated detoxif...

News Articles [203 Associated News Articles listed on BioPortfolio]

Merz North America Appoints Vice President, Chief Compliance Officer

Merz North America has announced the appointment of Salisa Hauptmann as Vice President and Chief Compliance Officer, effective March 9, 2015. In this role, Hauptmann will be responsible for providing ...

Merz North America Announces the Appointment of Salisa Hauptmann as Vice President, Chief Compliance Officer

Merz North America (U.S. affiliate of Merz Pharma Group) today announced the appointment of Salisa Hauptmann as Vice President and Chief Compliance Officer, effective March 9, 201...

Synthetic Biologics Announces Two Poster Presentations of Novel Monoclonal Antibody Combination for Treatment of Whooping Cough (Pertussis) at ECCMID 2015

ROCKVILLE, Md., March 2, 2015 /PRNewswire/ -- Synthetic Biologics, Inc. (NYSE MKT: SYN), a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting...

Is Topical Botox the Next Big Thing?

On February 24, 2015, Harper’s Bazaar Magazine’s website posted an article reporting on the development of a topical form of botulinum toxin type A. Dr. Simon Ourian of Epione Medical Corporation ...

Researchers develop quick test for fish toxin

Flinders University researchers have invented a revolutionary method to test for food poisoning in fish.

Pharmaceutical Research: Quantitative Evaluation of mMate1 Function Based on Minimally Invasive Measurement of Tissue Concentration Using PET with [11C]Metformin in Mouse

Type: Original PaperPurposeTo evaluate the function of multidrug and toxin extrusion proteins (MATEs) using 11C-labeled metformin ([11C]metformin) by positron emission tomography (PET).MethodsPET was ...

Research Study Highlights Promising New Mesothelioma Therapies, According to Surviving Mesothelioma

One of the country’s top mesothelioma researchers has published a new summary of some of the most promising emerging therapies for the deadly cancer. Raleigh, NC (PRWEB) February 25, 2015 UCLA’s ...

Oat Breakfast Cereals may Contain a Common Mold-Related Toxin

Oats are often touted for boosting heart health, but scientists warn that the grain and its products might need closer monitoring for potential mold contamination.

The Molecular Stool Revolution, Part 1: Why Molecular Testing for Stools?

In the first part of this two part series of webinars we will look at a brief history of bacterial stool cultures and Clostridium difficile toxin testing, d...

Botulism - Pipeline Review, H1 2015

Recently added to the BioPortfolio report store, Botulism - Pipeline Review, H1 2015 is a new report from Global Markets Direct published on 2015-01-21. This 34-page report is available in PDF from $...

Events [0 Results]

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Companies [7 Associated Companies listed on BioPortfolio]

Merz North America, Inc.

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in medical and aesthetic dermatology, and neurology in the U.S...

Merz North America

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in aesthetics, dermatology and neurology in the U.S. and Canad...

Merz, Inc.

Merz, Inc. is a focused specialty healthcare company that is responsible for developing and commercializing innovative products and solutions in neurology, medical aesthetics, and...

Pharmaleads

Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

Merz Aesthetics

Merz Aesthetics, the new business unit of Merz Pharma Group, is a leader in the global aesthetic medicine market. With a 100-year history of compassion and innovation in healthcare, Merz Aesthetics i...

DentaSpa

DentaSpa™ is one of the nation’s leading Botulinum Toxin, dermal fillers and injectables business education companies tailored exclusively for dental practitioners. Dent...

Clinical Trials [220 Associated Clinical Trials listed on BioPortfolio]

Botulinum Toxin Injection Versus Anal Myectomy in Management of Idiopathic Constipation

Chronic idiopathic constipation is most common cause of Constipation in childhood with numerous cases in Egypt. Numerous conservative measures were tried but many fail. Surgical options in...

Observational Study for Assessment of the Effect of Fampyra on the Manual Function of Persons With Multiple Sclerosis

Multiple Sclerosis (MS) is the most common chronic neurological disease affecting young adults, with onset usually at age 20-40 years. Women are affected 3-4 times more than men. The disea...

Safety of Sublingual dmLT for ETEC

A Phase 1 dose escalating study of ETEC candidate vaccine to determine safety and immunogenicity of a multi-dose regimen in healthy adult volunteers. The study will be conducted at Cincinn...

Safety and Immunogenicity Study of Recombinant Ricin Toxin A-Chain Vaccine (RVEc™)

This study is a Phase 1, escalating, multiple-dose, single-center study to evaluate the safety and immunogenicity of the RVEc vaccine. The two principal hypotheses to be tested are: RVEc ...

Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related Sialorrhea

Evaluation of the decrease of the secretion of saliva in patients with amyotrophic lateral sclerosis by a local ultrasound-guided bilateral injection of botulinum toxin type A in parotids ...

Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Leg After a Stroke

The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the leg are effective in treating patients with increased muscle tension/uncontrollab...

Botulinum Toxin A to Treat Arm Tremor

The objective of this study is to assess the efficacy and safety of a single, kinematic-analysis-based intramuscular injection of NT 201, compared with placebo, in moderate to marked essen...

Dysport® Adult Upper Limb Spasticity Extension Study

The purpose of this research study is to assess the long term safety of Dysport in hemiparetic subjects with upper limb spasticity due to stroke or traumatic brain injury over repeated tre...

Safety and Efficacy Study of Botulinum Toxin for the Treatment of Glabellar Frown Lines

The primary objective of the study is to evaluate the efficacy in wrinkle reduction of a single treatment of three different doses of botulinum toxin compared to placebo, in the treatment ...

Intravesicular Onabotulinumtoxin A in Interstitial Cystitis

The purpose of this research study is to identify the optimal usage of Onabotulinumtoxin A in interstitial cystitis. Onabotulinumtoxin A, more commonly known by the trade name Botox®, is ...

Medical and Biotech [MESH] Definitions

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.

Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.

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