Botulinum Toxin A Merz - Biotech, Pharma and Life Science Channel

11:12 EDT 21st October 2014 | BioPortfolio

PubMed Articles [688 Associated PubMed Articles listed on BioPortfolio]

CYN determination in tissues from freshwater fish by LC-MS/MS: Validation and application in tissues from subchronically exposed tilapia (Oreochromis niloticus).

Harmful cyanobacterial blooms are occurring in eutrophic freshwater lakes and reservoirs throughout the world and, because of the production of toxins such as cylindrospermopsin (CYN), they can presen...

Enhanced detection of the algal toxin PbTx-2 in marine waters by atmospheric pressure chemical ionization mass spectrometry.

Karenia brevis, a marine dinoflagellate, biosynthesizes a unique class of polyether toxins called brevetoxins that produce significant health, environmental and economic impacts in and along coastal w...

Rational Design of a BPA-Aptamer Selective SERS Nanoprobe.

Surface enhanced Raman scattering (SERS) optical nanoprobes offer a number of advantages for ultrasensitive analyte detection. These functionalized colloidal nanoparticles are a multifunctional assay ...

Esophageal perforation, inflammatory mediastinitis and pseudo-aneurysm of the thoracic aorta as potential complications of botulinum toxin injection for achalasia.

Primary achalasia is a motility disorder of the esophagus involving impaired relaxation of the esophageal sphincter and in later stages, dilatation and aperistalsis of the tubular esophagus. Endoscopi...

The effect of skin fatty acids on Staphylococcus aureus.

Staphylococcus aureus is a commensal of the human nose and skin. Human skin fatty acids, in particular cis-6-hexadecenoic acid (C-6-H), have high antistaphylococcal activity and can inhibit virulence ...

Switch from abobotulinumtoxinA (Dysport®) to incobotulinumtoxinA (Xeomin®) botulinum toxin formulation: A review of 257 cases.

Objective: To explore the dose equivalence ratio and treatment costs for abobotulinumtoxinA and incobotulinumtoxinA for patients with focal dystonias. Design: Patient chart review. Subjects/Patients: ...

The Intrinsically Disordered Domain of the Antitoxin Phd Chaperones the Toxin Doc Against Irreversible Inactivation and Misfolding.

The toxin Doc from the phd/doc toxin- antitoxin module targets the cellular translation machinery and is inhibited by its antitoxin partner Phd. Here we show that Phd also functions as a chaperone, ke...

Biophysical Characteristics of Cholera Toxin and Escherichia coli Heat-Labile Enterotoxin Structure and Chemistry Lead to Differential Toxicity.

The biophysical chemistry of macro molecular complexes confer their functional characteristics. We investigate the mechanisms that make the AB5 holotoxin of V. cholerae (CT) a significantly more patho...

Functional effects of botulinum toxin type-A treatment and subsequent stretching of spastic calf muscles: A study in patients with hereditary spastic paraplegia.

Objective: Although calf muscle spasticity is often treated with botulinum toxin type-A, the effects on balance and gait are ambiguous. Hereditary spastic paraplegia is characterized by progressive sp...

Polylysine-mediated translocation of the diphtheria toxin catalytic domain through the anthrax protective antigen pore.

The Protective Antigen (PA) moiety of anthrax toxin forms oligomeric pores in the endosomal membrane, which translocate the effector proteins of the toxin to the cytosol. Effector proteins bind to oli...

News Articles [202 Associated News Articles listed on BioPortfolio]

Tarantula venom illuminates electrical activity in live cells

(University of California - Davis Health System) Researchers have created a cellular probe that combines a tarantula toxin with a fluorescent compound to help scientists observe electrical activity in...

Tarantula toxin is used to report on electrical activity in live cells

(Marine Biological Laboratory) A novel probe that reports on the electrical activity of cells, made by fusing tarantula toxin with a fluorescent compound, is described in a paper today by scientists f...

AlphaVax, Inc. - Product Pipeline Review - 2014

Recently added to the BioPortfolio report store, AlphaVax, Inc. - Product Pipeline Review - 2014 is a new report from Global Markets Direct published on 2014-09-29. This 34-page report is available i...

New Report Details Rare Case of Mesothelioma from Winemaking, According to Surviving Mesothelioma

The case of mesothelioma in an Italian winemaker is a first for the industry, but may not be the last. Raleigh, NC (PRWEB) October 16, 2014 Cancer researchers in Italy are reporting the case of a man...

Top Reasons to Change Skincare Routine for Fall and Winter

Board-certified dermatologist Dr. William Groff discusses the best skincare practices for fall and winter San Diego, CA (PRWEB) October 16, 2014 A recent article from the Huffington Post talks about ...

Pediatric Written Requests Maintain Societal Value of BPCA Exclusivity, AAP Argues

Response to Merz citizen petition from American Academy of Pediatrics tells FDA that Congress didn’t intend for pediatric-only products to automatically gain exclusivity bonus.

Merz North America Announces the Appointment of Patrick Urban as Head of Ulthera Business Unit

Merz North America (U.S. affiliate of Merz Pharma Group) today announced the appointment of Patrick Urban as Head of the Ulthera Business Unit, which was acquired by Merz earlier ...

Response Biomedical Corp. Announces Funded Program and Equity Investment by Leading Chinese Medical Device Company

VANCOUVER, BRITISH COLUMBIA -- (Marketwired) -- 10/15/14 -- Response Biomedical Corp. ("Response" or "the Company") (TSX: RBM)(OTCBB: RPBIF) today announced that it has entered into a funded Technol...

Lake Erie increasingly susceptible to large cyanobacteria blooms

(University of Michigan) Lake Erie has become increasingly susceptible to large blooms of toxin-producing cyanobacteria since 2002, potentially complicating efforts to rein in the problem in the wake ...

PreferredOne Introduces Dr. Howard Epstein as Chief Medical Officer

GOLDEN VALLEY, Minn., Oct. 13, 2014 /PRNewswire/ -- PreferredOne today announced Dr. Howard Epstein as its executive vice president and chief medical officer. Epstein will be responsible for leading i...

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Companies [7 Associated Companies listed on BioPortfolio]

Merz North America, Inc.

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in medical and aesthetic dermatology, and neurology in the U.S...

Merz North America

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in aesthetics, dermatology and neurology in the U.S. and Canad...

Merz, Inc.

Merz, Inc. is a focused specialty healthcare company that is responsible for developing and commercializing innovative products and solutions in neurology, medical aesthetics, and...

Pharmaleads

Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

Merz Aesthetics

Merz Aesthetics, the new business unit of Merz Pharma Group, is a leader in the global aesthetic medicine market. With a 100-year history of compassion and innovation in healthcare, Merz Aesthetics i...

DentaSpa

DentaSpa™ is one of the nation’s leading Botulinum Toxin, dermal fillers and injectables business education companies tailored exclusively for dental practitioners. Dent...

Clinical Trials [202 Associated Clinical Trials listed on BioPortfolio]

Onabotulinum Toxin Type A and Abobotulinum Toxin Type A Crow's Feet Rhytid Study

The objective of the study is to compare the time to onset of Dysport® versus Botox® in the treatment of lateral orbital rhytids ("crow's feet"). Thirty subjects were enrolled in the stu...

The Use of Botulinum Toxin A in Two-Stage Tissue Expander/ Implant Breast Reconstruction

Breast reconstruction is a common procedure with over 86,000 breast reconstruction procedures performed in the United States in 2009. This is a 1.5-fold increase since 2007. Of these breas...

Long Term Follow-up Study of Safety and Efficacy of Botulinum Toxin Type A for the Treatment of Patients With Idiopathic Overactive Bladder With Urinary Incontinence

The purpose of this study is to assess the long term safety and effectiveness of botulinum toxin type A in treating patients with idiopathic overactive bladder with urinary incontinence.

Safety Study of DWP-450 (Botulinum Purified Neurotoxin, Type A) Injection to Treat Glabellar Lines

The purpose of this study is to demonstrate the safety of multiple doses of DWP-450 (Botulinum purified neurotoxin, Type A) Injection in treatment of moderate to severe glabellar lines in ...

Safety and Efficacy Study of Botulinum Toxin for the Treatment of Glabellar Frown Lines

The primary objective of the study is to evaluate the efficacy in wrinkle reduction of a single treatment of three different doses of botulinum toxin compared to placebo, in the treatment ...

MDs on Botox Utility (MOBILITY)

The MOBILITY Project is a prospective, non-randomized, observational, multi-centre evaluation of Health Utility via the SF-12® Health Survey Scores and the SF-6D in patients receiving BOT...

Host Immune Response to Clostridium Difficile Infection in Inflammatory Bowel Disease Patients

The inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's disease (CD) are chronic conditions affecting approximately 1.4 million Americans. The burden of Clostridium dif...

Study to Assess the Efficacy of Botulinum Toxin B (Myobloc) for the Treatment of Prosthesis-associated Sweating

The objective of this study is to determine if Myobloc significantly decreases prosthesis-associated symptomatic sweating in amputees when compared to a saline solution placebo. The study ...

Neuropathic Pain Study With Botulinum Toxin A in Spinal Cord Injury Patients

The purpose of this study is to determine whether botulinum toxin A is effective in the treatment of neuropathic pain in spinal cord injury patients.

Effect of Botulinum Toxin to Hallux Valgus in Addition to Total Contact Insole

The investigators propose a new therapeutic approach by injecting Botulinum Toxin Type A (BTA) to the oblique and transverse heads of adductor muscle of the great toe. BTA works by binding...

Medical and Biotech [MESH] Definitions

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.

Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.

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