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Botulinum Toxin A Merz - Biotech, Pharma and Life Science Channel

21:41 EDT 22nd July 2014 | BioPortfolio

PubMed Articles [700 Associated PubMed Articles listed on BioPortfolio]

Bacillus cereus and Bacillus thuringiensis spores in Korean rice: Prevalence and toxin production as affected by production area and degree of milling.

We determined the prevalence of and toxin production by Bacillus cereus and Bacillus thuringiensis in Korean rice as affected by production area and degree of milling. Rough rice was collected from 64...

Characterization of Aspergillus section Flavi isolated from organic Brazil nuts using a polyphasic approach.

Brazil nut (Bertholletia excelsa), an important non-timber forest product from Amazonia, is commercialized in worldwide markets. The main importers of this nut are North America and European countries...

Toxic Interaction between Th2 Cytokines and Staphylococcus aureus in Atopic Dermatitis.

Patients with atopic dermatitis (AD) are commonly colonized/infected with Staphylococcus aureus, and this bacterium is known to worsen the dermatitis. In this issue, Brauweiler et al. demonstrate a ne...

Microcystin production and regulation under nutrient stress conditions in toxic Microcystis strains.

Microcystin is a common and well known cyanobacteria toxin, which intracellular role is still under investigation. Increasing knowledge on microcystin gene expression and regulation can contribute to...

An in vitro culture model to study the dynamics of colonic microbiota in Syrian golden hamsters and their susceptibility to infection with Clostridium difficile.

Clostridium difficile infections (CDI) are caused by colonization and growth of toxigenic strains of C. difficile in individuals whose intestinal microbiota has been perturbed, in most cases following...

The Presence of the pAA Plasmid in the German O104:H4 Shiga toxin (Stx) type 2a-producing Enteroaggregative Escherichia coli Strain Promotes the Translocation of Stx2a across an Epithelial Cell Monolayer.

 A Shiga toxin (Stx) type 2a-producing enteroaggregative E. coli (EAEC) strain of serotype O104:H4 caused a large outbreak in 2011 in Northern Europe. Pathogenic mechanisms for this strain are uncle...

Protection from Hemolytic Uremic Syndrome by Eyedrop Vaccination with Modified Enterohemorrhagic E. coli Outer Membrane Vesicles.

We investigated whether eyedrop vaccination using modified outer membrane vesicles (mOMVs) is effective for protecting against hemolytic uremic syndrome (HUS) caused by enterohemorrhagic E. coli (EHEC...

Rhinovirus Infection Induces IL-13 Production from CD11b-positive, Exudative M2-polarized Exudative Macrophages.

Rhinovirus (RV) causes many asthma exacerbations. Previously, we showed that adherent bronchoalveolar cells from allergen-treated mice produce IL-13 when stimulated with RV ex vivo, implicating cells...

A Novel TNF-mediated Mechanism of Direct Epithelial Sodium Channel Activation.

Rationale. Alveolar liquid clearance (ALC) is regulated by Na(+)-uptake through the apically expressed epithelial sodium channel (ENaC) and the basolaterally localized Na(+)-K(+)-ATPase in type II alv...

Studies examining the relationship between the chemical structure of Protoxin II and its activity on Voltage Gated Sodium Channels.

The aqueous solution structure of protoxin II (ProTx II) indicated that the toxin is comprised of a well-defined inhibitor cystine knot (ICK) backbone region and a flexible C-terminal tail region, sim...

News Articles [219 Associated News Articles listed on BioPortfolio]

Synthetic Biologics' Academic Collaborator to Present Novel Monoclonal Antibody Combination for Treating Whooping Cough (Pertussis) at Gordon Research Conference

ROCKVILLE, Md., July 21, 2014 /PRNewswire/ -- Synthetic Biologics, Inc. (NYSE MKT: SYN), a developer of novel anti-infective biologic and drug candidates targeting specific pathogens that cause seriou...

Preventing foodborne illness naturally: with cinnamon

Cinnamomum cassia oil was shown to be effective as a natural antibacterial agent against several strains of Shiga toxin-producing Escherichia coli, known to the US Centers for Disease Control and Prev...

Merz North America to Establish Headquarters in Raleigh, North Carolina

Merz North America will establish its headquarters in Raleigh, North Carolina, officials announced today at a press conference with Gov. Pat McCrory. The global pharmaceutical com...

Preventing foodborne illness, naturally -- with cinnamon

(Washington State University) Cinnamomum cassia oil was shown to be effective as a natural antibacterial agent against several strains of Shiga toxin-producing Escherichia coli, known to the US Center...

Soligenix Reveals Combo Vaccine Against Anthrax And Ricin

Clinical stage biopharmaceutical company Soligenix announced that its combination vaccine composed of RiVax and VeloThrax successfully induced simultaneous, protective immunity to both ricin and anthr...

Potent spider toxin ‘electrocutes’ German, not American, cockroaches

Using spider toxins to study the proteins that let nerve […]

Ipsen and Galderma become exclusive partners for development and marketing of neurotoxins in the US, Canada, Brazil and Europe1

Ipsen and Galderma to expand their current distribution agreement for Dysport®/Azzalure® in aesthetic and dermatology indications to the US and Canada...

Potent spider toxin 'electrocutes' German, not American, cockroaches

(Johns Hopkins Medicine) Using spider toxins to study the proteins that let nerve cells send out electrical signals, Johns Hopkins researchers say they have stumbled upon a biological tactic that may...

Vaccine Achieves Simultaneous Protection Against Ricin, Anthrax

Soligenix Inc., a clinical stage biopharmaceutical company focused on developing products to treat serious inflammatory diseases where there remains an unmet medical need, as well as developing severa...

Galderma Finalizes Major Expansion in Aesthetic and Corrective Dermatology in the U.S. and Canada

FORT WORTH, Texas, July 10, 2014 /PRNewswire/ -- Galderma S.A. (Galderma) announced that it has gained full rights to distribute Restylane®, Perlane®, Emervel®, Sculptra® and...

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Companies [7 Associated Companies listed on BioPortfolio]

Merz North America, Inc.

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in medical and aesthetic dermatology, and neurology in the U.S...

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

DentaSpa

DentaSpa™ is one of the nation’s leading Botulinum Toxin, dermal fillers and injectables business education companies tailored exclusively for dental practitioners. Dent...

Merz North America

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in aesthetics, dermatology and neurology in the U.S. and Canad...

Merz, Inc.

Merz, Inc. is a focused specialty healthcare company that is responsible for developing and commercializing innovative products and solutions in neurology, medical aesthetics, and...

Pharmaleads

Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...

Merz Aesthetics

Merz Aesthetics, the new business unit of Merz Pharma Group, is a leader in the global aesthetic medicine market. With a 100-year history of compassion and innovation in healthcare, Merz Aesthetics i...

Clinical Trials [199 Associated Clinical Trials listed on BioPortfolio]

Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Arm After a Stroke

The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the upper limb are effective in treating spasticity in patients after stroke.

The Use of Botulinum Toxin A in Two-Stage Tissue Expander/ Implant Breast Reconstruction

Breast reconstruction is a common procedure with over 86,000 breast reconstruction procedures performed in the United States in 2009. This is a 1.5-fold increase since 2007. Of these breas...

Effect of Botulinum Toxin to Hallux Valgus in Addition to Total Contact Insole

The investigators propose a new therapeutic approach by injecting Botulinum Toxin Type A (BTA) to the oblique and transverse heads of adductor muscle of the great toe. BTA works by binding...

Neuropathic Pain Study With Botulinum Toxin A in Spinal Cord Injury Patients

The purpose of this study is to determine whether botulinum toxin A is effective in the treatment of neuropathic pain in spinal cord injury patients.

Host Immune Response to Clostridium Difficile Infection in Inflammatory Bowel Disease Patients

The inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's disease (CD) are chronic conditions affecting approximately 1.4 million Americans. The burden of Clostridium dif...

Study to Assess the Efficacy of Botulinum Toxin B (Myobloc) for the Treatment of Prosthesis-associated Sweating

The objective of this study is to determine if Myobloc significantly decreases prosthesis-associated symptomatic sweating in amputees when compared to a saline solution placebo. The study...

Does Botulinum Toxin Injections Improve Outdoor Activity in Children With Cerebral Palsy?- a Pilot Study

Background: Motor impairment limits social and recreational activities in children with cerebral palsy (CP), compromising participation and impacting on quality of life. Improvement of mo...

Botulinum a Toxin to Treat Patients With Painful Bladder Syndrome

Botulinum A toxin (BoNT/A) injections in patients with painful bladder syndrome (PBS) associated with increased urinary frequency refractory to conventional treatments versus bladder over...

The Effects of AST-120 on Endothelial Dysfunction in Patients With Chronic Kidney Disease

Indoxyl sulfate (IS) is a uremic toxin that accelerates the progression of chronic kidney disease (CKD). AST-120 (Kremezin®; Kureha Corporation, Tokyo, Japan) removes indole, which is the...

A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GSK1358820 (Botulinum Toxin Type A) in Chinese Subjects With Post-stroke Upper Limb Spasticity

This trial is a multicenter, double-blind, randomized, placebo-controlled study to compare GSK1358820 with placebo on the efficacy and safety of treatment in poststroke subjects with focal...

Medical and Biotech [MESH] Definitions

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.

Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.

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