Botulinum Toxin A Merz - Biotech, Pharma and Life Science Channel

18:40 EDT 30th May 2015 | BioPortfolio

PubMed Articles [676 Associated PubMed Articles listed on BioPortfolio]

Potentiation of the effect of a commercial animal feed additive mixed with different probiotic yeast strains on the adsorption of aflatoxin B1.

This study potentiates the adsorbent effect for aflatoxin B1 (AFB1) of a commercial additive (CA) of animal feed, containing inactive lysate of three Saccharomyces cerevisiae strains, active enzymes, ...

Medication- and Toxin-Induced Neurologic Syndromes.

Patients who present with mixed clinical neurologic signs and symptoms can be sorted into groups based on the symptom format. Targeted physical examination and evaluation of laboratory results can hel...

Intramural Injection with Botulinum Toxin Type A in Piglet Esophagus. The Influencer on Maximum Load and Elongation: A Dose Response Study.

Introduction The treatment of esophageal atresia (OA) is challenging. The main goal is to achieve primary anastomosis. We have previously demonstrated in a pig model that intramural injection of bot...

Phosphatidylcholine Specific PLC-Induced Dysregulation of Gap Junctions, a Robust Cellular Response to Environmental Toxicants, and Prevention by Resveratrol in a Rat Liver Cell Model.

Dysregulation of gap junctional intercellular communication (GJIC) has been associated with different pathologies, including cancer; however, molecular mechanisms regulating GJIC are not fully underst...

Whole Transcriptome of the Venom Gland from Urodacus yaschenkoi Scorpion.

Australian scorpion venoms have been poorly studied, probably because they do not pose an evident threat to humans. In addition, the continent has other medically important venomous animals capable of...

Pseudomonas aeruginosa ExoT Induces Atypical Anoikis Apoptosis in Target Host Cells by Transforming Crk Adaptor Protein into a Cytotoxin.

Previously, we demonstrated that Pseudomonas aeruginosa ExoT induces potent apoptosis in host epithelial cells in a manner that primarily depends on its ADP-ribosyltransferase domain (ADPRT) activity....

Treatment of Blepharospasm in Schwartz-Jampel Syndrome: Botulinum Toxin A Injection or Surgery.

Schwartz-Jampel syndrome is an autosomal recessive disease that comprises facial and musculoskeletal deformity. Hereby, the authors report 2 cases of Schwartz-Jampel syndrome and surgical method of th...

RELATIONSHIP BETWEEN EXTRACELLULAR LOW MOLECULAR WEIGHT THIOLS AND MERCURY SPECIES IN NATURAL LAKE PERIPHYTIC BIOFILMS.

The uptake of mercury by microorganisms is a key step in the production of methylmercury, a biomagnifiable toxin. Mercury complexation by low molecular weight (LMW) thiols can affect its bioavailabili...

Micropatterned Macrophage Analysis Reveals Global Cytoskeleton Constraints Induced by Bacillus anthracis Edema Toxin.

Bacillus anthracis secretes the edema toxin (ET) that disrupts the cellular physiology of endothelial and immune cells, ultimately affecting the adherens junction integrity of blood vessels that in tu...

A versatile, non genetically modified organism (GMO)-based strategy for controlling low-producer mutants in Bordetella pertussis cultures using antigenic modulation.

The uncontrolled presence of non-producer mutants negatively affects bioprocesses. In Bordetella pertussis cultures, avirulent mutants emerge spontaneously and accumulate. We characterized the dynamic...

News Articles [216 Associated News Articles listed on BioPortfolio]

Aflatoxin Linked to Risk of Gallbladder Cancer

Aflatoxin, a naturally occurring toxin produced by certain types of molds, has been found to be associated with an increased risk of gallbladder cancer.

Merz Pharma GmbH & Co. KgaA - Medical Equipment - Deals and Alliances Profile

Recently added to the BioPortfolio report store, Merz Pharma GmbH & Co. KgaA - Medical Equipment - Deals and Alliances Profile is a new report from GlobalData published on 2015-04-19. This 29-pag...

Clostridium difficile toxin B (TcdB); poliovirus receptor-related 3 (PVRL3)

Cell culture studies suggest inhibiting the TcdB-

Roche's Clostrodium difficile test receives FDA clearance

A Clostridium difficile test developed by Roche for detecting the toxin B gene in patients' stool samples has received 510(k) -More- 

A versatile, non genetically modified organism (GMO)‐based strategy for controlling low‐producer mutants in Bordetella pertussis cultures using antigenic modulation

The uncontrolled presence of non‐producer mutants negatively affects bioprocesses. In Bordetella pertussis cultures, avirulent mutants emerge spontaneously and accumulate. We characterized the dynam...

Crescendo Biologics Expands ADC Programmes with Innovate UK Funding Award

CAMBRIDGE, England, May 27, 2015 /PRNewswire/ -- Biomedical Catalyst Award to Support Development of New Therapies to Target Prostate Cancer  Crescendo Biologics Limited (Crescendo) today annou...

Study finds association between exposure to aflatoxin and gallbladder cancer

In a small study in Chile that included patients with gallbladder cancer, exposure to aflatoxin (a toxin produced by mold) was associated with an increased risk of gallbladder cancer, according to a s...

Lipella Pharmaceuticals, Inc. - Pharmaceuticals & Healthcare - Deals and Alliances Profile

Recently added to the BioPortfolio report store, Lipella Pharmaceuticals, Inc. - Pharmaceuticals & Healthcare - Deals and Alliances Profile is a new report from GlobalData published on 2015-04-08...

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

Zhao et al. report that brain vessels have a major role in clearing Alzheimer's disease-related toxin Aβ from brain, and show that PICALM gene product and its variant associated with an increased ris...

Roche receives FDA clearance for the cobas® Cdiff Test to detect Clostridium difficile

PLEASANTON, Calif., May 26, 2015 /PRNewswire/ -- Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that the US Food and Drug Administration (FDA) has provided 510(k) clearance for the cobas...

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Companies [8 Associated Companies listed on BioPortfolio]

Pharmaleads

Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...

OCuSOFT, Inc.

OCuSOFT, Inc. is a privately-held Richmond, TX USA-based ophthalmic research, development and supply company with an established reputation for innovation, particularly in the are...

Merz North America, Inc.

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in medical and aesthetic dermatology, and neurology in the U.S...

Merz North America

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in aesthetics, dermatology and neurology in the U.S. and Canad...

Merz, Inc.

Merz, Inc. is a focused specialty healthcare company that is responsible for developing and commercializing innovative products and solutions in neurology, medical aesthetics, and...

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

Merz Aesthetics

Merz Aesthetics, the new business unit of Merz Pharma Group, is a leader in the global aesthetic medicine market. With a 100-year history of compassion and innovation in healthcare, Merz Aesthetics i...

DentaSpa

DentaSpa™ is one of the nation’s leading Botulinum Toxin, dermal fillers and injectables business education companies tailored exclusively for dental practitioners. Dent...

Clinical Trials [227 Associated Clinical Trials listed on BioPortfolio]

BOTOX® Treatment in Pediatric Lower Limb Spasticity

This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) in pediatric patients with lower limb spasticity.

Botulinum Toxin A Injections in Patients With Fowler's Syndrome

Hypothesis / aims of study Urinary retention is uncommon in young women, and one cause is a primary disorder of urethral sphincter relaxation, characterised by an elevated urethral pressu...

Botulinum Toxin for the Treatment of Trigeminal Neuralgia

IncobotulinumtoxinA (Xeomin®) is a neurotoxin which inhibits the release of certain chemicals at the nerve terminals. It blocks cholinergic transmission at the neuromuscular junction by...

Safety and Efficacy of Botulinum Toxin Type A (BOTOX®) to Treat Chronic Migraine in Korea

This study is a Post-Marketing Surveillance study in Korea to evaluate the safety and efficacy of botulinum toxin Type A to treat Chronic Migraine in clinical practice.

BOTOX® Treatment in Pediatric Upper Limb Spasticity

This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) in pediatric patients with upper limb spasticity.

Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Abnormal Contraction or Twitch of the Eyelid

This phase 3 study will serve to collect efficacy and safety data of two different doses of NT 201 in subjects suffering from Bilateral Blephorasm (BEB) who are BTX treatment-naïve. In t...

Apitox, Honeybee Toxin for Pain and Inflammation of Osteoarthritis

The study will identify the efficacy of Apitox, purified honeybee toxin, in 330 patients with diagnosed osteoarthritis of the knee. The subjects will be evaluated for relief of pain using...

Botulinum Toxin Injection to Prevent Ventricular Arrhythmias

The aim of this prospective non-randomized study was to assess the efficacy and safety of endomyocardial botulinum toxin injection in left ventricle for preventing ventricular arrhythmias.

Safety of Sublingual dmLT for ETEC

A Phase 1 dose escalating study of ETEC candidate vaccine to determine safety and immunogenicity of a multi-dose regimen in healthy adult volunteers. The study will be conducted at Cincinn...

Botox Injection in Treatment of Chronic Migraine

Chronic migraine is in many cases a most disabling condition. Chronic migraine is defined as headaches for at least 15 days per month, of which 8 days have typical migraine features. In ma...

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Medical and Biotech [MESH] Definitions

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.

Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.

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