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Botulinum Toxin A Merz - Biotech, Pharma and Life Science Channel

16:51 EDT 25th September 2017 | BioPortfolio

PubMed Articles [630 Associated PubMed Articles listed on BioPortfolio]

Development and validation of a maleimide-based enzyme-linked immunosorbent assay for the detection of tetrodotoxin in oysters and mussels.

The recent detection of tetrodotoxins (TTXs) in puffer fish and shellfish in Europe highlights the necessity to monitor the levels of TTXs in seafood by rapid, specific, sensitive and reliable methods...

Uremic toxins are conditional danger- or homeostasis-associated molecular patterns.

We mined novel uremic toxin (UT) metabolomics/gene databases, and analyzed the expression changes of UT receptors and UT synthases in chronic kidney disease (CKD) and cardiovascular disease (CVD). We ...

Hemoadsorption corrects hyperresistinemia and restores anti-bacterial neutrophil function.

Mounting evidence suggests that sepsis-induced morbidity and mortality are due to both immune activation and immunosuppression. Resistin is an inflammatory cytokine and uremic toxin. Septic hyperresis...

Degradation and inactivation of Shiga toxins by nitrogen gas plasma.

Shiga toxin (Stx)-producing Escherichia coli (STEC) leads to food poisoning by causing hemorrhagic colitis and hemolytic uremic syndrome. Some STEC produce Shiga toxin 1 (Stx1) and/or Shiga toxin 2 (S...

Targeted therapy of human glioblastoma via delivery of a toxin through a peptide directed to cell surface nucleolin.

Targeted anticancer therapies demand discovery of new cellular targets to be exploited for the delivery of toxic molecules and drugs. In this perspective, in the last few years, nucleolin has been ide...

Primary T cells for mRNA-mediated immunotoxin delivery.

Immune cells become increasingly attractive as delivery system for immunotoxins in cancer therapy in order to reduce the intrinsic toxicity and severe side effects of chimeric protein toxins. In this ...

Characterization of Diarrheagenic Escherichia coli Isolated in Organic Waste Products (Cattle Fecal Matter, Manure and, Slurry) from Cattle's Markets in Ouagadougou, Burkina Faso.

Cattle farming can promote diarrheal disease transmission through waste, effluents or cattle fecal matter. The study aims to characterize the diarrheagenic Escherichia coli (DEC) isolated from cattle ...

Cellular Entry of the Diphtheria Toxin Does Not Require the Formation of the Open-Channel State by Its Translocation Domain.

Cellular entry of diphtheria toxin is a multistage process involving receptor targeting, endocytosis, and translocation of the catalytic domain across the endosomal membrane into the cytosol. The latt...

Asymmetric Cryo-EM Structure of Anthrax Toxin Protective Antigen Pore with Lethal Factor N-Terminal Domain.

The anthrax lethal toxin consists of protective antigen (PA) and lethal factor (LF). Understanding both the PA pore formation and LF translocation through the PA pore is crucial to mitigating and perh...

Humoral Response of Buffaloes to a Recombinant Vaccine against Botulism Serotypes C and D.

Botulism is a fatal intoxication caused by botulinum neurotoxins (BoNTs), which are mainly produced by Clostridium botulinum and characterized by flaccid paralysis. The BoNTs C and D are the main sero...

News Articles [198 Associated News Articles listed on BioPortfolio]

Poison Frogs Evolved Poison Resistance via Complementary Mutations

Brightly colored but capable of dark deeds, poison frogs have evolved several ways to accumulate toxic chemicals that are harmful to predators, or the merely curious, while being harmless to the frogs...

Cans of 'Death Wish' coffee recalled over possible toxin

NEW YORK (Reuters) - Death Wish Coffee Co, a New York coffee maker that sells what it says is the "World's Strongest Coffee," is recalling cans of its Nitro Cold Brew because of the risk that some cou...

Merz Named the Top Aesthetics Company By Aesthetic Everything®

Merz North America CEO Bob Rhatigan named the Top Aesthetics CEO Cellfina® and Ultherapy® Also Recognized as Top Procedures Merz North America, Inc. announced today...

Only lethal if sugar is present

The plant toxin ricin is one of the most poisonous naturally occurring proteins, making it an extremely dangerous bioweapon. Ricin attacks have made the headlines a number of times over the years, in...

Glythera and IONTAS Enter into License Agreement for the Development of Multiple Antibodies for Next-Generation Antibody Drug Conjugates

IONTAS will provide Glythera with antibodies from its fully human antibody libraries Glythera will use these antibodies, in combination with its novel ...

Revance to Participate in the Cantor Fitzgerald 2017 Global Healthcare Conference

Revance Therapeutics, Inc. (NASDAQ:RVNC), a biotechnology company developing botulinum toxin products for use in aesthetic and therapeutic indications, today announced that the co...

Identification of a Tetanus Toxin Specific Epitope in Single Amino Acid Resolution

Vaccinations are among the most potent tools to fight infectious diseases. However, cross‐reactions are an ongoing problem and there is an urgent need to fully understand the mechanisms of the immun...

Global Hyaluronic Acid Dermal Filler Market Data Survey Report 2025 [Report Updated: 29082017] Prices from USD $1500

SummaryHyaluronic Acid Dermal Filler are the product can be used to smooth away wrinkles and fine line, create fuller and more accentuated lips, and adding facial volume and contour.The global Hyaluro...

Ipsen Announces Analysis of Managed Medicaid Data of Children with Cerebral Palsy at Annual Meeting of the American Academy of Cerebral Palsy and Developmental Medicine

42 Percent of Children with Cerebral Palsy Not Receiving Spasticity Management Therapies, According to Retrospective Study on Medicaid Costs Ipsen Biopharmaceuticals, I...

Revance Therapeutics Inc RVNC Pharmaceuticals Healthcare Deals and Alliances Profile [Report Updated: 23082017] Prices from USD $250

SummaryRevance Therapeutics Inc Revance Therapeutics develops, manufactures and commercializes novel botulinum toxin products. The company's product candidate includes RT002, an injectable formulation...

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Companies [13 Associated Companies listed on BioPortfolio]

Merz Pharma Canada Ltd.

Merz Pharma Canada Ltd. a wholly owned subsidiary of the Merz Group of Companies was established in 2009 to expand Merz franchises in the Canadian Marketplace.

Merz Pharmaceuticals

Merz Pharmaceuticals, LLC is a part of Merz, Inc., a wholly owned U.S. subsidiary of the Merz Group of Companies and was established in 1995 to develop and commercialize products for the Merz Group. ...

Merz Pharma GmbH & Co. KGaA

Merz Neurosciences

Merz Neurosciences is a division of Merz North America, a specialty healthcare company that develops and commercializes treatment solutions in aesthetics, dermatology and neurosci...

Merz Inc.

Pharmaleads

Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...

OCuSOFT, Inc.

OCuSOFT, Inc. is a privately-held Richmond, TX USA-based ophthalmic research, development and supply company with an established reputation for innovation, particularly in the are...

Merz North America, Inc.

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in medical and aesthetic dermatology, and neurology in the U.S...

Merz North America

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in aesthetics, dermatology and neurology in the U.S. and Canad...

Merz, Inc.

Merz, Inc. is a focused specialty healthcare company that is responsible for developing and commercializing innovative products and solutions in neurology, medical aesthetics, and...

Clinical Trials [368 Associated Clinical Trials listed on BioPortfolio]

Protein-bound Toxin Removal Between Limited Blood Flow Super High-flux Online HDF and High-Efficiency Online HDF

High-efficiency post-dilution online hemodiafiltration (OL-HDF) using high-flux dialyzer and requiring high blood flow rate (BF ≥400 mL/min) has been reported to enhance protein-bound to...

Botox for Gummy Smile

This is a two part study to measure and observe the efficacy of botulinum toxin A for the treatment of gummy smiles. Part A will randomly compare three different doses of botulinum toxin ...

Efficacy Comparison Between Different Management Strategies for Consistent OAB in Patients With SVMs After Surgery

The investigators' goal is to compare the efficacy of three different management stategies(sacral neuromodulation, botulinum toxin, M receptor antagonist) in treating consistent OAB in pat...

Abdominal Ultrasonography in Urinary Tract Infection - When and Why?

Urinary tract infection (UTI) in a child may be the first symptom of congenital anomaly of the kidneys and the urinary tract (CAKUT). Thus, imaging diagnostics are warranted in children wi...

A Mechanical Device for Blepharospasm

Idiopathic blepharospasm (IB) is a rare but well characterised adult onset focal dystonia that may cause severe visual disability. The most effective treatment is with periodic injections ...

A Phase III Study to Evaluate the Efficacy and Safety of GSK1358820 in Subjects With Post-stroke Upper Limb Spasticity

Botulinum toxin A (GSK1358820) is a sterile, purified type A botulinum neurotoxin complex. In Japan, 240 units of botulinum toxin A are approved as a maximum dose per administration for up...

Evaluation of the Sensitivity of Merz Lips Fullness Assessment Scale Following Etermis 4® Treatment for Lips Volume Augmentation

Primary objective: - To evaluate the sensitivity of the Merz Lip Fullness Assessment Scale (MLFAS). Secondary objectives: - To evaluate the clinical aesthetic improvement outco...

Pain During Injection With Botulinum Toxin in Post-stroke Spasticity Treatment

The aim of the study was to analyze which step of the procedure of toxin botulinum injection is the most painful between skin break-in, electric stimulation, injection and needle withdrawa...

A Multimodal Approach to Cervical Dystonia Treatment With Association of Botulinum Toxin and Motor Learning Techniques

the aim of this study protocol is to describe, using a longitudinal study, a multimodal approach of treatment of cervical dystonia with botulinum toxin (BoNTA) and a new rehabilitation pro...

Botulinum Toxin for Cramps in Diabetic Neuropathy

Objective: previous studies suggest that botulinum toxin A (BoNT/A) can reduce muscle hyperactivity. Research Design and Methods: a single-center, double-blind and placebo-controlled stud...

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Medical and Biotech [MESH] Definitions

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.

Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.

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