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Botulinum Toxin A Merz - Biotech, Pharma and Life Science Channel

11:56 EDT 30th June 2016 | BioPortfolio

PubMed Articles [663 Associated PubMed Articles listed on BioPortfolio]

Engineered bacterial toxin as a courier.

Identification of an alkaline phosphatase as a putative Cry1Ac binding protein in Ostrinia furnacalis (Guenée).

Asian corn borer (ACB), Ostrinia furnacalis, is an important insect pest of maize susceptible to different Cry1A toxins. Based on amino acid sequence alignment of ALP sequences from lepidopteran larva...

Heat Wave-Associated Vibriosis, Sweden and Finland, 2014.

During summer 2014, a total of 89 Vibrio infections were reported in Sweden and Finland, substantially more yearly infections than previously have been reported in northern Europe. Infections were spr...

(1)H(N), (13)C, and (15)N resonance assignments of the CDTb-interacting domain (CDTaBID) from the Clostridium difficile binary toxin catalytic component (CDTa, residues 1-221).

Once considered a relatively harmless bacterium, Clostridium difficile has become a major concern for healthcare facilities, now the most commonly reported hospital-acquired pathogen. C. difficile inf...

C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors.

C3 exoenzyme from C. botulinum is an ADP-ribosyltransferase that inactivates selectively RhoA, B, and C by coupling an ADP-ribose moiety. Rho-GTPases are involved in various cellular processes, such a...

Preoperative chemical component relaxation using Botulinum toxin A: enabling laparoscopic repair of complex ventral hernia.

Repair of complex ventral hernia can be very challenging for surgeons. Closure of large defects can have serious pathophysiological consequences. Botulinum toxin A (BTA) has recently been described to...

Plasmon Coupling Enhanced Raman Scattering Nanobeacon for Single-Step, Ultrasensitive Detection of Cholera Toxin.

We report the development of a novel plasmon coupling enhanced Raman scattering (PCERS) method, PCERS nanobea-con, for ultrasensitive, single-step, homogeneous detection of cholera toxin (CT). This me...

Genomic Diversity of Enterotoxigenic Strains of Bacteroides fragilis.

Enterotoxigenic (ETBF) strains of Bacteroides fragilis are the subset of strains that secrete a toxin called fragilysin (Bft). Although ETBF strains are known to cause diarrheal disease and have recen...

Evaluation of the Spectral Response of Functionalized Silk Inverse Opals as Colorimetric Immunosensors.

Regenerated silk fibroin is a high molecular weight protein obtained by purifying the cocoons of the domesticated silkworm, Bombyx mori. This report exploits the aqueous processing and tunable β shee...

Ant and Mite Diversity Drives Toxin Variation in the Little Devil Poison Frog.

Poison frogs sequester chemical defenses from arthropod prey, although the details of how arthropod diversity contributes to variation in poison frog toxins remains unclear. We characterized skin alka...

News Articles [224 Associated News Articles listed on BioPortfolio]

Heart Disease No. 1 Cause Of Death For Americans

Cancer comes in at No. 2, and combined they cause nearly 50 percent of all deaths in the country. Also in the news, church attendance is linked to lower suicide rates, the struggle of helping aging pa...

This month’s toughest USMLE Step 2 question to master

Getting ready for the United States Medical Licensing Examination® (USMLE®) Step 2 is no easy feat, but we’re sharing expert insights to help give you a leg up. Take a look at the exclusive scoo...

How Anthrax Toxin Proteins Might Help Treat Cancerous Tumors

NewsThe bacterium Bacillus anthracis produces a toxin made of three proteins that individually are non-toxic. Contributed Author: 

Botulinum Toxin Injections to the "11s" Between the Brows Produce Significant Patient Satisfaction Rates According to FACE-Q Survey

NEW YORK, June 28, 2016 /PRNewswire-USNewswire/ -- Botulinum toxin type A injections are the most common cosmetic procedure performed in the United States, with 4.3 million procedures performed i...

FDA Consumer Health Information: Raw Dough's a Raw Deal and Could Make You Sick

SILVER SPRING, Md., June 28, 2016 /PRNewswire-USNewswire/ -- Do you find it hard to resist gobbling up a piece of raw dough when making cookies, or letting your children scrape the bowl? Do your kids ...

BRIEF-Great Basin receives CE Mark for Shiga Toxin Direct Test

* Shiga Toxin direct test available for use outside of U.S., having earned CE marking designation Source text for Eikon: Further company coverage: (Bengaluru Newsroom: +1 646 223 8780)

Great Basin Receives CE Mark for Shiga Toxin Direct Test

Standalone molecular test that detects Shiga toxin-producing E. coli (STEC) now available for use outside the United States Read more...

Scientists explain how engineered anthrax toxin proteins could help eliminate cancerous tumors

Scientists from the National Institute of Allergy and Infectious Diseases, the National Institute of Dental and Craniofacial Research, and the National Heart, Lung and Blood Institute all parts of the...

Scientists decode how anthrax toxin proteins might help treat cancerous tumors

Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), the National Institute of Dental and Craniofacial Research (NIDCR), and the National Heart, Lung and Blood Institute ...

Researchers investigate what causes cattle to shed shiga toxin-producing Escherichia coli

Shiga toxin-producing Escherichia coli (STEC) are foodborne pathogens spread largely by cattle, that can cause hemorrhagic colitis and kidney failure. In an effort to find ways of reducing this proble...

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Companies [11 Associated Companies listed on BioPortfolio]

Merz Pharma GmbH & Co. KGaA

Merz Neurosciences

Merz Neurosciences is a division of Merz North America, a specialty healthcare company that develops and commercializes treatment solutions in aesthetics, dermatology and neurosci...

Merz Inc.

Pharmaleads

Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...

OCuSOFT, Inc.

OCuSOFT, Inc. is a privately-held Richmond, TX USA-based ophthalmic research, development and supply company with an established reputation for innovation, particularly in the are...

Merz North America, Inc.

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in medical and aesthetic dermatology, and neurology in the U.S...

Merz North America

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in aesthetics, dermatology and neurology in the U.S. and Canad...

Merz, Inc.

Merz, Inc. is a focused specialty healthcare company that is responsible for developing and commercializing innovative products and solutions in neurology, medical aesthetics, and...

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

Merz Aesthetics

Merz Aesthetics, the new business unit of Merz Pharma Group, is a leader in the global aesthetic medicine market. With a 100-year history of compassion and innovation in healthcare, Merz Aesthetics i...

Clinical Trials [283 Associated Clinical Trials listed on BioPortfolio]

Children Toxine Botulinum Detrusor Injection in Neurogenic Vesical Hyperactivity Syndrom: Non Inferiority Multicenter Controlled Therapeutic Study Between Two Reported Weight's Doses

Detrusor hyperactivity is an urodynamic observation defined by involuntary detrusor contractions during the vesical filling. Within neurological bladders childs, especially related to spin...

Treatment of Temporo-Myofascial Disorder of Muscular Origin Using Botulinum Toxin: A Prospective Study

Temporomandibular disorders (TMD) are a group of conditions involving the temporomandibular joint (TMJ), masticatory muscles and associated structures. This broad complex of functional dis...

Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Chronic Rhinosinusitis With Nasal Polyposis

Chronic rhinosinusitis (CRS) with nasal polyps is a particularly challenging form of chronic rhinosinusitis in several ways. Patients have significantly more severe symptom burden and wors...

Evaluation of the Improvement of Quality of Life of Patients Suffering From Hailey Hailey or Darier Disease After Injections of Botulism Toxin Into Large Folds.

Hailey Hailey and Darier disease are rare genetic dermatoses. Mutations of 2 genes (ATP2C1 or ATP2A2 respectively) are responsible for the diseases. These genes have a key role in calcium ...

Phase I, Dose Escalation Study to Evaluate the Safety and Pharmacokinetics of NTM-1632

This is a Phase I, randomized, double-blind, placebo controlled dose escalation trial to evaluate NTM-1632 in three dose cohorts (A: 0.033 mg/kg, B: 0.165 mg/kg, and C: 0.33 mg/kg). NTM-16...

Botulinum Toxin A as a Treatment for Provoked Vestibulodynia

Women with provoked vestibulodynia (PVD) suffer from severe dyspareuni and often present a hyperactivity of the pelvic floor muscles (PFM) which maintain the dyspareunia. The rationale for...

Comparison Between Steroid and Different Sites of Botulinum Toxin Injection in the Treatment of Lateral Epicondylalgia

The aim of the study is to compare two different injection sites of low dose botulinum toxin type A with steroid in treating lateral epicondylalgia.

Comparative Hybrid Effects of Combining BoNT-A With Robot-assisted or Mirror Therapy for U/E Spasticity Stroke Patients

The aim of this study will be to determine and compare the immediate and longer-term effects of combination of BoNT-A injection and mirror therapy vs combination of BoNT-A injection and ro...

A Study to Examine the Effects of Cosmeceutical Therapy in Subjects Undergoing Full Facial Rejuvenation

The primary objective of this study is to determine the efficacy of Sensi Peel®, Rejuvenating Serum, and the C&E Strength Max skin care products in subjects who undergo full facial rejuve...

Effect of Repeated Botulinum Toxin Injection on Gait Pattern in Stroke Patients

Chronic stroke patients exhibit gait pattern alterations which are mainly due to spasticity and treated with repetitive multifocal botulinum toxin injection(BTI). Several studies demonstra...

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Medical and Biotech [MESH] Definitions

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.

Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.

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