Botulinum Toxin A Merz - Biotech, Pharma and Life Science Channel

19:11 EDT 2nd July 2015 | BioPortfolio

PubMed Articles [672 Associated PubMed Articles listed on BioPortfolio]

Sortase Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody Drug Conjugates with High In Vitro and In Vivo Potency.

Antibody drug conjugates (ADCs) have recently been proven to be highly potent anti-tumor drugs, typically exceeding the efficacy of conventional monoclonal antibodies (mAbs). ADCs are currently produc...

Canonical Single Nucleotide Polymorphisms (SNPs) for High-Resolution Subtyping of Shiga-Toxin Producing Escherichia coli (STEC) O157:H7.

The objective of this study was to develop a canonical, parsimoniously-informative SNP panel for subtyping Shiga-toxin producing Escherichia coli (STEC) O157:H7 that would be consistent with epidemiol...

Management of neurogenic lower urinary tract dysfunction in multiple sclerosis patients.

Multiple sclerosis (MS) can be a debilitating neurological condition that attributes significant morbidity to bladder dysfunction. Although many effective treatment options exist, symptomatic patients...

The management of overactive bladder: percutaneous tibial nerve stimulation, sacral nerve stimulation, or botulinum toxin?

We have reviewed the evidence published on botulinum toxin A (BoNT/A), percutaneous tibial nerve stimulation (PTNS), and sacral nerve stimulation (SNS) in the management of overactive bladder (OAB).

The Effect of Botox on the Implant Stabilization and Capsular Formation: An Experimental Study.

Breast augmentation is one of the most common esthetic procedures with increasing frequency throughout the past years. The most demanding complications involving esthetic and reconstructive breast sur...

Botulinum Toxin Type B for Chronic Pain: Panacea or Snake Oil? The Need for More and Better Preclinical Studies.

Erratum on: Absence of Bacterial or Fungal Growth in Vials of Reconstituted Botulinum Toxin Type A After Storage.

Intraspecies interaction of Fusarium graminearum contributes to reduced toxin production and virulence.

Fusarium graminearum is a pathogenic fungus that causes Fusarium Head Blight in wheat and lowers the yield and quality of grains by contamination with the trichothecene mycotoxin, deoxynivalenol. The ...

Natural Occurrence of Alternaria Toxins in Wheat-Based Products and Their Dietary Exposure in China.

A total of 181 wheat flour and 142 wheat-based foods including dried noodle, steamed bread and bread collected in China were analyzed for alternariol (AOH), alternariol monomethyl ether (AME), tentoxi...

Neonatal Pulmonary Macrophage Depletion Coupled to Defective Mucus Clearance Increases Susceptibility to Pneumonia and Alters Pulmonary Immune Responses.

Resident immune cells [e.g., macrophages (MΦ)] and airway mucus clearance both contribute to a healthy lung environment. To investigate interactions between pulmonary MΦ function and defective mucus...

News Articles [210 Associated News Articles listed on BioPortfolio]

Merz Pharmaceuticals GmbH - Product Pipeline Review - 2015

Merz Pharmaceuticals GmbH - Product Pipeline Review - 2015 Summary Global Markets Direct’s, ‘Merz Pharmaceuticals GmbH - Product Pipeline Review - 2015’, provides an overview of the Merz Pharmac...

'Pulse' Technology May Replenish Skin's Collagen

Americans spend over $10 billion a year on products and surgery in their quest to find a "fountain of youth," with little permanent success. Botulinum toxin -- notably Botox -- which smoothes lines an...

Fish-Related Food Poisoning in Florida Under-Reported

MONDAY, June 29, 2015 -- A rare toxin carried by barracuda, grouper and other locally caught sport fish sickens Floridians in greater numbers than previously believed, a new analysis suggests. Consumi...

More people in Florida sickened by toxin in tropical reef fish than previously reported

Public health records may significantly underestimate the number of people in Florida who are sickened by a rare, dangerous food-borne toxin carried by popular sport fish, including barracuda, grouper...

Bacterial physiology: Obg controls bacterial persistence

A new study shows that the GTPase Obg controls bacterial persistence by causing membrane depolarization via a mechanism that involves transcriptional activation of the toxin gene hokB.

Merz Neurosciences Launches Awareness Campaign for Patients with Voice Disorders

Merz Neurosciences Bringing Attention to a Common Issue Merz Neurosciences, a division of Merz North America (US affiliate of the global Merz Pharma Group) announces the launc...

Merz North America Announces the Appointment of David Dobrowski as Vice President, Head of North American Research and Development

Merz North America (U.S. affiliate of Merz Pharma Group) today announced the appointment of David Dobrowski as Vice President and Head of North American Research and Development, ...

Global Scar Treatment Market Will Reach US$ 31,904.8 Mn by 2022 : Persistence Market Research

New York, NY, June 21, 2015 --(PR.com)-- According to a new market report published by Persistence Market Research “Global Market Study on Scar Treatment: Asia to Witness Highest Growth by 2022...

Novel botulinum toxin less dangerous than thought

When a team of California researchers reported a new type of botulinum toxin in 2013, they withheld genetic data on the lethal toxin out of concern that malefactors could use […]

Botox: It's Not Just for Wrinkles

Albertson, NY (PRWEB) June 17, 2015 In 2002, the FDA approved the use of injected botulinum toxin type A for temporary reduction in the appearance of wrinkles between the eyebrows. It soon became a...

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Companies [8 Associated Companies listed on BioPortfolio]

Pharmaleads

Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...

OCuSOFT, Inc.

OCuSOFT, Inc. is a privately-held Richmond, TX USA-based ophthalmic research, development and supply company with an established reputation for innovation, particularly in the are...

Merz North America, Inc.

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in medical and aesthetic dermatology, and neurology in the U.S...

Merz North America

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in aesthetics, dermatology and neurology in the U.S. and Canad...

Merz, Inc.

Merz, Inc. is a focused specialty healthcare company that is responsible for developing and commercializing innovative products and solutions in neurology, medical aesthetics, and...

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

Merz Aesthetics

Merz Aesthetics, the new business unit of Merz Pharma Group, is a leader in the global aesthetic medicine market. With a 100-year history of compassion and innovation in healthcare, Merz Aesthetics i...

DentaSpa

DentaSpa™ is one of the nation’s leading Botulinum Toxin, dermal fillers and injectables business education companies tailored exclusively for dental practitioners. Dent...

Clinical Trials [231 Associated Clinical Trials listed on BioPortfolio]

Two-week Course Versus Conventionally Fractionated Chemoradiotherapy in Rectal Cancer

The investigators compare two-week course of chemoradiation (33 Gy in 10 fractions with oral capecitabine) and conventional chemoradiation (50.4 Gy in 28 fractions with 5-FU and leucovorin...

Intra Individual Evaluation of Uremic Toxin Levels in Hemodialysed Patients

Chronic kidney disease (CKD) is characterized by a irreversible decrease of kidney functions. It is characterized by accumulation of solutes called uremic toxins. Uremic toxins levels are ...

The Use of Botox in Advanced Parkinson's Patients Experiencing Pain

Most Parkinsonism related pain can be assigned to one or more of five categories: musculoskeletal pain, neuritic or radicular pain, dystonia associated pain, primary or central pain, and a...

Botulinim Toxin Type A Injections by Different Guidance in Stroke Patients With Spasticity on Lower Extremities

Stroke may result in lower extremity spasticity, which interfere with motor voluntary function and activities of daily living. Botulinum toxin type A (BTX-A) has been shown to improve lowe...

Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Abnormal Contraction or Twitch of the Eyelid

This phase 3 study will serve to collect efficacy and safety data of two different doses of NT 201 in subjects suffering from Bilateral Blephorasm (BEB) who are BTX treatment-naïve. In t...

BOTOX® Treatment in Pediatric Lower Limb Spasticity

This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) in pediatric patients with lower limb spasticity.

Botulinum Toxin A Injections in Patients With Fowler's Syndrome

Hypothesis / aims of study Urinary retention is uncommon in young women, and one cause is a primary disorder of urethral sphincter relaxation, characterised by an elevated urethral pressu...

Botulinum Toxin for the Treatment of Trigeminal Neuralgia

IncobotulinumtoxinA (Xeomin®) is a neurotoxin which inhibits the release of certain chemicals at the nerve terminals. It blocks cholinergic transmission at the neuromuscular junction by...

Safety and Efficacy of Botulinum Toxin Type A (BOTOX®) to Treat Chronic Migraine in Korea

This study is a Post-Marketing Surveillance study in Korea to evaluate the safety and efficacy of botulinum toxin Type A to treat Chronic Migraine in clinical practice.

BOTOX® Treatment in Pediatric Upper Limb Spasticity

This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) in pediatric patients with upper limb spasticity.

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Medical and Biotech [MESH] Definitions

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.

Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.


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