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Botulinum Toxin A Merz - Biotech, Pharma and Life Science Channel

15:40 EST 6th February 2016 | BioPortfolio

PubMed Articles [671 Associated PubMed Articles listed on BioPortfolio]

Ochratoxin A and T-2 Toxin Induce Clonogenicity and Cell Migration in Human Colon Carcinoma and Fetal Lung Fibroblast Cell Lines.

T-2 toxin and Ochratoxin A (OTA) are toxic secondary metabolites produced by various fungi, and together they contaminate feedstuffs worldwide. T-2 toxin and OTA may exert carcinogenic action in roden...

Colonization of Beef Cattle by Shiga Toxin-Producing Escherichia coli during the First Year of Life: A Cohort Study.

Each year Shiga toxin-producing Escherichia coli (STEC) are responsible for 2.8 million acute illnesses around the world and > 250,000 cases in the US. Lowering the prevalence of this pathogen in anim...

Free-Ranging Frigates (Fregata magnificens) of the Southeast Coast of Brazil Harbor Extraintestinal Pathogenic Escherichia coli Resistant to Antimicrobials.

Seabirds may be responsible for the spread of pathogenic/resistant organisms over great distances, playing a relevant role within the context of the One World, One Health concept. Diarrheagenic E. col...

Seroprevalence of Antibodies to Pertussis Toxin among Different Age Groups in Thailand after 37 Years of Universal Whole-Cell Pertussis Vaccination.

Despite the high coverage of prophylactic vaccine against Bordetella pertussis infection in many countries for more than three decades, pertussis remains a common vaccine-preventable disease. Infectio...

Mutated form (G52E) of inactive diphtheria toxin CRM197: molecular simulations clearly display effect of the mutation to NAD binding.

Mutated form (G52E) of diphtheria toxin (DT) CRM197 is an inactive and nontoxic enzyme. Here, we provided a molecular insight using comparative molecular dynamics (MD) simulations to clarify the influ...

Isolation of Shiga Toxin-Producing Escherichia coli from Ground Beef Using Multiple Combinations of Enrichment Broths and Selective Agars.

Shiga toxin-producing Escherichia coli (STEC) are foodborne pathogens, and beef cattle are recognized as the principal reservoir. The aims of this study were (1) to identify the most sensitive combina...

Evaluation of the non-toxic mutant of the diphtheria toxin K51E/E148K as carrier protein for meningococcal vaccines.

Diphtheria toxin mutant CRM197 is a common carrier protein for glycoconjugate vaccines, which has been proven an effective protein vector for, among others, meningococcal carbohydrates. The wide-range...

Reviewing the reviewers: critical appraisal of "Effect of intragastric injection of botulinum toxin A for the treatment of obesity: a meta-analysis and meta-regression".

Bordetella pertussis Strain Lacking Pertactin and Pertussis Toxin.

A Bordetella pertussis strain lacking 2 acellular vaccine immunogens, pertussis toxin and pertactin, was isolated from an unvaccinated infant in New York State in 2013. Comparison with a French strain...

Agonist-Induced Activation of Histamine H3 Receptor Signals to Extracellular Signal-Regulated Kinases 1 and 2 through PKC-, PLD- and EGFR-dependent Mechanisms.

The histamine H3 receptor (H3R), abundantly expressed in the central and the peripheral nervous system, has been recognized as a promising target for the treatment of various important CNS diseases in...

News Articles [214 Associated News Articles listed on BioPortfolio]

Global Market Study on Facial Rejuvenation: Early onset of Ageing and Rising Adoption of minimally Invasive Procedures to Drive the Market, Persistence Market Research

LONDON, Feb. 4, 2016 /PRNewswire/ -- This Persistence Market Research (PMR) report examines the 'Global Facial rejuvenation Market for the period 2015-2021. The primary objective of the report is to o...

New Galderma Campaign Encourages Women To Love Their "Mom Genes"

FORT WORTH, Texas, Feb. 4, 2016 /PRNewswire/ -- Women everywhere know that the mother-daughter bond can run deep. Mothers pass down wisdom, advice and inspiration to their daughters – and, ...

GenSpera, Pursuing Partners, Tests Toxin-Based Drug in Brain Cancer

Like many small biotechs, San Antonio, TX-based GenSpera has plenty of options for developing its cancer drug and limited resources to do so. While GenSpera’s treatment, called mipsagargin or G-202,...

Effect of detrusor botulinum toxin a injection on urothelial dysfunction in patients with chronic spinal cord injury: a clinical and immunohistochemistry study before and after treatment

CDC Declares Multistate Outbreaks of E. coli Infection to Be Over

The Centers for Disease Control and Prevention (CDC) says that the multistate outbreaks of Shiga toxin-producing Escherichia coli O26 infections linked to Chipotle Mexican Grill restaurants appear to ...

New Innovative Technique Makes Fillers Last Longer

Eagan, MN, dermatologist Charles E. Crutchfield III, MD, says that neurotoxin injections can help achieve longer lasting results from dermal fillers. Twin Cities, MN (PRWEB) January 29, 2016 When wor...

LSU Health New Orleans technology part of $90 million pharma deal

(Louisiana State University Health Sciences Center) A technology invented by faculty at LSU Health New Orleans is part of an acquisition deal by Allergan plc, a global pharmaceutical company. Allergan...

Kibow Biotech Continues to Document the "Enteric Dialysis" Concept Towards Modulation of the Gut Microbiome With RENADYL

This year's annual American society of Nephrology (ASN) 2015 Kidney Week conference was held at the San Diego Convention Center, Nov 3-8.1 Kibow Biotech, Inc. was pleased to mark its 10th year of cont...

Figure: Gut movement

Hitchhiker's guide to the gut Product R&D Gut movement Applied Molecular Transport LLC (AMT) has co-opted the infection route of a bacterial toxin to create Transint, an oral biologics platform that c...

Priority Review for Merck's bezlotoxumab

Merck & Co Inc. (NYSE:MRK) said FDA accepted for filing and granted Priority Review to a BLA for bezlotoxumab (MK-6072) to treat recurrent Clostridium difficile infection. Its PDUFA date is July 23.Me...

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Companies [10 Associated Companies listed on BioPortfolio]

Merz Neurosciences

Merz Neurosciences is a division of Merz North America, a specialty healthcare company that develops and commercializes treatment solutions in aesthetics, dermatology and neurosci...

Merz Inc.

Pharmaleads

Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...

OCuSOFT, Inc.

OCuSOFT, Inc. is a privately-held Richmond, TX USA-based ophthalmic research, development and supply company with an established reputation for innovation, particularly in the are...

Merz North America, Inc.

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in medical and aesthetic dermatology, and neurology in the U.S...

Merz North America

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in aesthetics, dermatology and neurology in the U.S. and Canad...

Merz, Inc.

Merz, Inc. is a focused specialty healthcare company that is responsible for developing and commercializing innovative products and solutions in neurology, medical aesthetics, and...

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

Merz Aesthetics

Merz Aesthetics, the new business unit of Merz Pharma Group, is a leader in the global aesthetic medicine market. With a 100-year history of compassion and innovation in healthcare, Merz Aesthetics i...

DentaSpa

DentaSpa™ is one of the nation’s leading Botulinum Toxin, dermal fillers and injectables business education companies tailored exclusively for dental practitioners. Dent...

Clinical Trials [268 Associated Clinical Trials listed on BioPortfolio]

Safety and Efficacy Study of Intravesical Instillations of BotuGelTM, Slow Release RTGel Based Botox® Formulations, in Idiopathic OAB Patients With Urinary Incontinence ("INTIMO2")

The study will investigate the safety and efficacy of UroGen's TC-3 Gel for sustained release of Botulinum Toxin A (BTX) in urinary bladder in patients with idiopathic overactive bladder.

Observational Study of Botulinum Toxin Type A in Patients With Urinary Incontinence Associated With Overactive Bladder

This study will describe the prescription conditions of botulinum toxin Type A (Botox®) injection for the treatment of urinary incontinence due to neurogenic detrusor overactivity (NDO) o...

Kinematic Characterization of Upper Limb Parkinson's Disease Tremor for Optimized Botulinum Toxin Type A Therapy

The primary objective is to study the efficacy of botulinum toxin type A (BoNT-A) injected via kinematic parameters in the treatment of unilateral/bilateral upper extremity tremor in Parki...

Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Trigeminal Neuralgia. Safety Issues.

Trigeminal neuralgia is one of the strongest pains known to humans. Some patients do not have enough effect with the available pharmaceutical treatments and are offered surgery. There are ...

Peroral Endoscopic Myotomy Versus Botulinum Toxin Injection in Spastic Esophageal Disorders

To compare the efficacy of peroral endoscopic myotomy and Botulinum toxin injection in spastic esophageal disorders.

Clinical and Kinematic Assessment for Determination of Botox® Injection Parameters in Cervical Dystonia

This study investigates the use of a kinematic measurement device to quantify the abnormal head movements and postures in patients with cervical dystonia (CD) in order to individualize and...

Botulinum Toxin is a Potential Prophylactic Therapy for Minimizing Post-excisional Scarring (Allergan Botox Scar Study)

Dermatological surgeons wear many hats to care for subjects with skin cancer. While their role in cancerous tissue removal results in superior cure rates, there is also a need for skilled ...

Glycerol Block of the Trigeminal Ganglion in Trigeminal Neuralgia Using a New Neuronavigation-based Surgical Technique

Trigeminal neuralgia is one of the strongest pains known to humans. Some patients do not have enough effect with the available pharmaceutical treatments and are offered a type of surgery, ...

Botulinum Toxin A for Shoulder Pain After Stroke

Shoulder pain after stroke is a very common, causing significant morbidity disease. Subacromial and subdeltoid (SASD) bursitis are common causes of pain or disability of the shoulder joint...

Botulinum Toxin Injection Into Epicardial Fat Pads to Prevent Atrial Fibrillation in Patients Undergoing Cardiac Surgery

The aim of this prospective randomized double-blind study was to compare the efficacy of botulinum toxin injection in epicardial fat pads for preventing recurrences (in early postoperative...

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Medical and Biotech [MESH] Definitions

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.

Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.

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