Botulinum Toxin A Merz - Biotech, Pharma and Life Science Channel

21:48 EST 21st December 2014 | BioPortfolio

PubMed Articles [670 Associated PubMed Articles listed on BioPortfolio]

CYN determination in tissues from freshwater fish by LC-MS/MS: Validation and application in tissues from subchronically exposed tilapia (Oreochromis niloticus).

Harmful cyanobacterial blooms are occurring in eutrophic freshwater lakes and reservoirs throughout the world and, because of the production of toxins such as cylindrospermopsin (CYN), they can presen...

Analysis of Bordetella pertussis clinical isolates circulating in European countries during the period 1998-2012.

Despite more than 50 years of vaccination, pertussis is still an endemic disease, with regular epidemic outbreaks. With the exception of Poland, European countries have replaced whole-cell vaccines (...

Prevalence of carriers of Shiga toxin-producing Escherichia coli serotypes O157:H7, O26:H11, O103:H2, O111:H8 and O145:H28 in French slaughtered adult cattle.

The main pathogenic enterohemorrhagic Escherichia coli (EHEC) are defined as Shiga toxin (Stx)-producing E. coli (STEC) belonging to one of the following serotypes: O157:H7, O26:H11, O103:H2, O111:H8 ...

Centrifugal Microfluidic Platform for Ultra-sensitive Detection of Botulinum Toxin.

We present an innovative centrifugal microfluidic immunoassay platform (SpinDx) to address the urgent biodefense and public health need for ultra-sensitive point-of-care/incident detection of botulinu...

Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis.

During endocytosis, energy is invested to narrow the necks of cargo-containing plasma membrane invaginations to radii at which the opposing segments spontaneously coalesce, thereby leading to the deta...

In vitro Transcriptome Analysis of Two Chinese Isolates of Streptococcus suis Serotype 2.

The Streptococcus suis serotype 2 (S. suis 2) isolates 05ZYH33 and 98HAH33 have caused severe human infections in China. Using a strand-specific RNA-seq analysis, we compared the in vitro transcriptom...

Novel Expression Vectors Enabling Induction of Gene Expression by Small-Interfering RNAs and MicroRNAs.

Small-interfering RNAs and microRNAs are small ∼21-22 nucleotide long RNAs capable of posttranscriptional suppression of gene expression. The synthetic siRNAs are especially designed to target pre-s...

Mesomartoxin, a new Kv1.2-selective scorpion toxin interacting with the channel selectivity filter.

Venom-derived neurotoxins are ideal probes for the investigation of structure-function relationship of ion channels and promising scaffolds for the design of ion channel-targeted drug leads as well. T...

Building heterogeneous core-satellite chiral assemblies for ultrasensitive toxin detection.

A chiral-aptasensor for ochratoxin A (OTA) detection based on Au core-Ag nanoparticle satellite assemblies was fabricated for the first time. High yields of Au core-Ag NP satellite assemblies were pre...

Transcriptome Sequencing Reveals the Virulence and Environmental Genetic Programs of Vibrio vulnificus Exposed to Host and Estuarine Conditions.

Vibrio vulnificus is a natural inhabitant of estuarine waters worldwide and is of medical relevance due to its ability to cause grievous wound infections and/or fatal septicemia. Genetic polymorphisms...

News Articles [216 Associated News Articles listed on BioPortfolio]

Planet Biotechnology Inc. - Product Pipeline Review - 2014

Recently added to the BioPortfolio report store, Planet Biotechnology Inc. - Product Pipeline Review - 2014 is a new report from Global Markets Direct published on 2014-12-14. This 25-page report is ...

Resurrecting a magic bullet

Heidelberg Pharma has resuscitated a long-dead ADC toxin with updated conjugation techniques, and its partner Roche has thrown the company a lifeline that could help validate the platform.

Officials Finish Sweep of Federal Labs, Find Handful of Misplaced Microbes

(Washington Post) – Investigators poring through thousands of government labs turned up another two dozen potentially dangerous biological materials that were not properly accounted for, includi...

Tarzana Dermatologist, Dr. Peyman Ghasri, is Now Offering a Discount on Combination of Dysport and Restylane

Tarzana dermatologist, Dr. Peyman Ghasri, is now offering a discount on the popular combination of Dysport and Restylane treatments until the New Year. Tarzana, CA (PRWEB) December 16, 2014 Tarzana d...

2015 Medical Conference agenda for 3rd Annual Primary Care Continuing Medical Education Maui conference has been released by Continuing Education Company

The agenda for the medical conference, "3rd Annual Primary Care Winter CME Conference", has been released by the Continuing Education Company. This medical conference is from February 16-20...

Discovery aims to fight destructive bee disease

(University of Guelph) University of Guelph researchers hope their new discovery will help combat a disease killing honeybee populations around the world. The researchers have found a toxin released b...

Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis

During endocytosis, energy is invested to narrow the necks of cargo-containing plasma membrane invaginations to radii at which the opposing segments spontaneously coalesce, thereby leading to the deta...

Renowned San Diego Dermatologist Will Be Featured on Upcoming Episode of “The Doctors”

Board-certified dermatology expert Dr. William Groff participated in an episode of the Emmy award-winning television show that will air on Monday, December 15th. San Diego, CA (PRWEB) December 15, 201...

Response Biomedical Corp. Renegotiates Term Loan with Silicon Valley Bank

VANCOUVER, BRITISH COLUMBIA -- (Marketwired) -- 12/15/14 -- Response Biomedical Corp. ("Response" or "the Company") (TSX: RBM)(OTCBB: RPBIF) announced that the Company has entered into an Amendment ...

Response Biomedical Corp. Announces Closing of Private Placement

VANCOUVER, BRITISH COLUMBIA -- (Marketwired) -- 12/12/14 -- Response Biomedical Corp. ("Response" or the "Company") (TSX: RBM)(OTCBB: RPBIF) is pleased to announce the closing of the previously anno...

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Companies [7 Associated Companies listed on BioPortfolio]

Merz North America, Inc.

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in medical and aesthetic dermatology, and neurology in the U.S...

Merz North America

Merz North America is a specialty healthcare company that develops and commercializes innovative treatment solutions in aesthetics, dermatology and neurology in the U.S. and Canad...

Merz, Inc.

Merz, Inc. is a focused specialty healthcare company that is responsible for developing and commercializing innovative products and solutions in neurology, medical aesthetics, and...

Pharmaleads

Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

Merz Aesthetics

Merz Aesthetics, the new business unit of Merz Pharma Group, is a leader in the global aesthetic medicine market. With a 100-year history of compassion and innovation in healthcare, Merz Aesthetics i...

DentaSpa

DentaSpa™ is one of the nation’s leading Botulinum Toxin, dermal fillers and injectables business education companies tailored exclusively for dental practitioners. Dent...

Clinical Trials [215 Associated Clinical Trials listed on BioPortfolio]

Botulinum Toxin A to Treat Arm Tremor

The objective of this study is to assess the efficacy and safety of a single, kinematic-analysis-based intramuscular injection of NT 201, compared with placebo, in moderate to marked essen...

Safety of Sublingual dmLT for ETEC

A Phase 1 dose escalating study of ETEC candidate vaccine to determine safety and immunogenicity of a multi-dose regimen in healthy adult volunteers. The study will be conducted at Cincinn...

Dysport® Adult Upper Limb Spasticity Extension Study

The purpose of this research study is to assess the long term safety of Dysport in hemiparetic subjects with upper limb spasticity due to stroke or traumatic brain injury over repeated tre...

Safety and Efficacy Study of Botulinum Toxin for the Treatment of Glabellar Frown Lines

The primary objective of the study is to evaluate the efficacy in wrinkle reduction of a single treatment of three different doses of botulinum toxin compared to placebo, in the treatment ...

Intravesicular Onabotulinumtoxin A in Interstitial Cystitis

The purpose of this research study is to identify the optimal usage of Onabotulinumtoxin A in interstitial cystitis. Onabotulinumtoxin A, more commonly known by the trade name Botox®, is ...

Arm Spasticity - Non-Interventional Study Early BIRD (BoNT Treatment: Initial and Repeated Documentation) [AS-NIS Early BIRD]

Botulinum toxin A (BoNT-A) is effective and safe in alleviating post-stroke spasticity and reducing the burden of associated symptoms. The hypothesis for this non-interventional study in ...

Incobotulinum Toxin A (Xeomin®) As A Treatment For Focal Task-Specific Dystonia Of The Musician's Hand

The investigational drug being studied in this protocol is Incobotulinumtoxin A (Xeomin®). Botulinum toxin (BoNT) prevents the release of the acetylcholine from peripheral nerves, inhibit...

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

Background: - Researchers who are studying hairy cell leukemia, and how the disease compares with other disorders, are interested in obtaining additional samples from leukemia patients an...

Botox Injection in Treatment of Chronic Migraine

Chronic migraine is in many cases a most disabling condition. Chronic migraine is defined as headaches for at least 15 days per month, of which 8 days have typical migraine features. In ma...

BOTOX® Treatment in Pediatric Upper Limb Spasticity

This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) in pediatric patients with upper limb spasticity.

Medical and Biotech [MESH] Definitions

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.

Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.

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