Botulinum Toxin B - Biotech, Pharma and Life Science Channel
PubMed Articles
Critical Roles of a Dendritic Cell Subset Expressing a Chemokine Receptor, XCR1.
Dendritic cells (DCs) consist of various subsets that play crucial roles in linking innate and adaptive immunity. In the murine spleen, CD8α(+) DCs exhibit a propensity to ingest dying/dead cells, pr...
Neonate-to-adult transition of snake venomics in the short-tailed pit viper, Gloydius brevicaudus.
Snake venoms undergo ontogenetic shifts in biochemical and pharmacological activities. This may be related to variation in venom components associated with the ontogenetic shift in diet. We used the s...
Graphene and Graphene Oxide Materials for Chemo- and Biosensing of Chemical and Biochemical Hazards.
Graphene, a new member of the carbon family, has attracted enormous attention due to its very peculiar properties like high surface area, mechanical strength, and conductivity. Moreover, graphene is e...
Agonist-induced desensitization of human β3-adrenoceptors expressed in human embryonic kidney cells.
β3-Adrenoceptors are resistant to agonist-induced desensitization in some cell types but susceptible in others including transfected human embryonic kidney (HEK) cells. Therefore, we have studied cel...
This report describes a novel diagnostic assay for rapid detection of the Panton-Valentine Leukocidin (PVL) toxin of methicillin-resistant Staphylococcus aureus (MRSA) utilizing resistive pulse sensin...
Rapid mass spectrometric determination of disulfide connectivity in peptides and proteins.
Disulfide crosslinks are ubiquitous in natural peptides and proteins, providing rigidity to polypeptide scaffolds. The assignment of disulfide connectivity in multiple crosslinked systems is often dif...
C-di-GMP is a second messenger in bacteria and partly regulates bacterial physiology by binding to class I and II riboswitches. Four class I c-di-GMP riboswitch aptamer candidates, Ct-E88, Cb-17B, Cb-...
A chimeric protein was constructed expressing three epitopes of LiD1, a dermonecrotic toxin from the venom of Loxosceles intermedia spider. This species is responsible for a large number of accidents...
Bites by Australian black snakes (Pseudechis spp.) do not cause neurotoxicity in human envenoming. This is unusual as in vitro neurotoxicity has been reported for all Pseudechis spp. venoms. The prese...
Bacterial toxin inhibitors based on multivalent scaffolds.
Protein toxins released by certain intestinal bacteria are the cause of many diarrhoeal diseases including cholera and travellers' diarrhoea. The toxins enter their target cells by first binding to sp...
News Articles
Toxic chemicals exist in many of the products people use to prepare their children for summer camp. Essential Safe Products sheds light on health concerns that could be linked to potentially harmful i...
Response Biomedical Corp. Announces Voting Results
VANCOUVER, BRITISH COLUMBIA -- (Marketwired) -- 06/19/13 -- Response Biomedical Corp. (TSX: RBM) (OTCBB: RPBIF) (the "Company"), in accordance with the requirements of the Toronto Stock Exchange, is...
Onabotulinum toxin injection in neurogenic detrusor overactivity: intradetrusor versus suburothelial
Botulinum Toxin Benefits Many PSP Patients With Dystonia
For patients with progressive supranuclear palsy, botulinum toxin A injections relieve disabling blepharospasm and neck and hand dystonia. The greatest benefit is in treating blepharospasm. Medscape...
New Survey Reveals One in Five Women Have Information They Keep Secret from their Doctors
IRVINE, Calif., June 18, 2013 /PRNewswire-USNewswire/ -- Women are frequently the healthcare advocate for their loved ones or families, but unfortunately they often do not give the same priority...
Engineered Anthrax Toxin Variants that Target Cancer
This technology describes the use of novel mutated anthrax protective antigen (PA) protein variants to target tumor cells and tumor vasculature. NIH scientists have engineered two PA variants that se...
Eyelid Disorder Controlled with Botulinum Toxin (CME/CE)
SYDNEY (MedPage Today) -- Patients with blepharospasm related to Parkinson's disease, an involuntary closure of the eyelid caused by spasms of the ocular muscles, can get relief with injections of bot...
Botulinum Toxin Good Long-Term in Dystonia (CME/CE)
SYDNEY (MedPage Today) -- After at least 10 years of treatment, dystonia patients receiving botulinum neurotoxin continued to achieve symptom relief at the same magnitude and at virtually the same dos...
Doctors Rarely Get Proper Consent for Botulinum Treatments
Botulinum toxin injections can have adverse effects, but adequate consent is rarely obtained from patients. Formal consent was deficient at the time of a first injection and even more so at subsequent...
Another test of Bt GMO food --rice that is - for gastrointestinal health (Open Access)
Effects of genetically modified T2A-1 rice on the GI health of rats after 90-day supplementBacillus thuringiensis insecticidal toxin (Bt) rice will be commercialized as a main food source. Traditional...
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Companies
Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...
Pharmaleads is a research company focussed on the custom design of substrates and inhibitors of zinc metallopeptidases and proteases. Pharmaleads has already developed molecules for ECE, NEP, ACE, APN...
Clinical Trials
The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the upper limb are effective in treating spasticity in patients after stroke.
Neuropathic Pain Study With Botulinum Toxin A in Spinal Cord Injury Patients
The purpose of this study is to determine whether botulinum toxin A is effective in the treatment of neuropathic pain in spinal cord injury patients.
The Use of Botulinum Toxin A in Two-Stage Tissue Expander/ Implant Breast Reconstruction
Breast reconstruction is a common procedure with over 86,000 breast reconstruction procedures performed in the United States in 2009. This is a 1.5-fold increase since 2007. Of these breas...
Host Immune Response to Clostridium Difficile Infection in Inflammatory Bowel Disease Patients
The inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's disease (CD) are chronic conditions affecting approximately 1.4 million Americans. The burden of Clostridium dif...
Botox as a Treatment for Chronic Male Pelvic Pain Syndrome
Chronic pelvic pain syndrome (CPPS) is thought to affect approximately 8% of men aged 18 and older. Patients with this condition experience pain in the perineum, the genitalia, and the rec...
Botox as a Treatment for Interstitial Cystitis in Women
Patients with interstitial cystitis have been well documented to have pelvic floor muscle tenderness as well as pain on bladder distension. Some investigators have even suggested that pel...
Vanderbilt University Spasticity Management Program Evaluation Plan
People with severe developmental disabilities frequently have comorbidities that make providing care to them more difficult. Spasticity is one such comorbidity. It produces increased muscl...
The primary aim of the study is to show that the antibody response to hepatitis B, acellular pertussis toxin and inactivated poliovirus antigens after the 4th vaccination with Hexavac® is...
The purpose of this study is to continue the work from the previous review study and determine the effectiveness of Botox in treating patients with idiopathic clubfoot by comparing outcome...
Deep Brain Stimulation to Treat Cervical Dystonia
This study will evaluate the effectiveness of deep brain stimulation (DBS) for treating primary dystonia. Patients with dystonia have muscle spasms that cause uncontrolled twisting and rep...
Videos
dr kris reddy reviews botulinum toxin treatments e.g. b
Dr Kris Reddy reviews Botulinum Toxin Treatments e.g. botox & dysport. Dr. Reddy cares for South Florida botox patients including West Palm Beach botox, West...
Medical and Biotech [MESH] Definitions
Pertussis Toxin
One of the virulence factors produced by BORDETELLA PERTUSSIS. It is a multimeric protein composed of five subunits S1 - S5. S1 contains mono ADPribose transferase activity.
Adenylate Cyclase Toxin
One of the virulence factors produced by virulent BORDETELLA organisms. It is a bifunctional protein with both ADENYLATE CYCLASE and hemolysin components.
Clostridium Botulinum Type A
Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXIN TYPE A which is neurotoxic to humans and animals.
Clostridium Botulinum Type B
Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.
Clostridium Botulinum Type C
Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.
