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Brain Death - Biotech, Pharma and Life Science Channel

06:32 EDT 18th May 2013 | BioPortfolio

PubMed Articles [ 12342 Associated PubMed Articles listed on BioPortfolio]

Nonylphenol-induced apoptotic cell death in mouse TM4 Sertoli cells via the generation of reactive oxygen species and activation of the ERK signaling pathway.

Nonylphenol (NP), a representative endocrine disruptor, interferes with reproductive function in aquatic organisms and animals. Although many previous studies have focused on apoptotic cell death by N...

Acetyl-CoA the Key Factor for Survival or Death of Cholinergic Neurons in Course of Neurodegenerative Diseases.

Glucose-derived pyruvate is a principal source of acetyl-CoA in all brain cells, through pyruvate dehydogenase complex (PDHC) reaction. Cholinergic neurons like neurons of other transmitter systems an...

Stereotactic laser induced thermotherapy (LITT): a novel treatment for brain lesions regrowing after radiosurgery.

Since the inception of radiosurgery, the management of brain metastases has become a common problem for neurosurgeons. Although the use of stereotactic radiosurgery and/or whole brain radiation therap...

PQ1, a quinoline derivative, induces apoptosis in T47D breast cancer cells through activation of caspase-8 and caspase-9.

Apoptosis, a programmed cell death, is an important control mechanism of cell homeostasis. Deficiency in apoptosis is one of the key features of cancer cells, allowing cells to escape from death. Acti...

Bufalin induces G2/M phase arrest and triggers autophagy via the TNF, JNK, BECN-1 and ATG8 pathway in human hepatoma cells.

Liver cancer is the fifth most common cause of cancer death worldwide. The study of more effective anti-hepatoma drugs is urgently required. Bufalin has been isolated from a traditional Chinese medici...

Ontogenetic patterns of morphological variation in the ectocranial human vault.

The skull is considered a modular structure in which different parts are influenced by different factors and, as a result, achieve adult shape at different ages. Previous studies have suggested that t...

The Superficial Glia Limitans of Mouse and Monkey Brain and Spinal Cord.

Using the double immunostaining method, the glia limitans on the surfaces of mouse and monkey brain and spinal cord were studied systematically. The results showed that the superficial glia limitans o...

Classic models for dynamic contrast-enhanced MRI.

Dynamic contrast-enhanced MRI (DCE-MRI) is a functional MRI method where T1 -weighted MR images are acquired dynamically after bolus injection of a contrast agent. The data can be interpreted in terms...

Neuroradiology in Duckburg.

Apoptosis-inducing factor (AIF) and leukocyte elastase inhibitor/L-DNase II (LEI/LDNaseII), can interact to conduct caspase-independent cell death.

Programmed cell death is an important factor in tissue homeostasis. Lot of work has been performed to characterize the caspase-dependent cell death. Caspase-independent cell death, although important...

News Articles [ 12498 Associated News Articles listed on BioPortfolio]

Insomnia Treatment | How “Sleep Brain Waves” Helps People Cure Their Insomnia – HealthReviewCenter.com

“Sleep Brain Waves," developed by Ryan Bolera, is a new insomnia treatment method that reveals the main causes of insomnia and guides on how to treat these causes. A full Sleep Brain Waves revi...

Spontaneous brain activity in amygdala higher among combat veterans with PTSD

Chronic trauma can inflict lasting damage to brain regions associated with fear and anxiety. Previous imaging studies of people with post-traumatic stress disorder, or PTSD, have shown that these brai...

Transcranial random noise stimulation allows the brain to work more efficiently, say researchers

In the future, if you want to improve your ability to manipulate numbers in your head, you might just plug yourself in. So say researchers who report in the Cell Press journal Current Biology on May 1...

Research findings could lead to new therapies for stroke and other brain diseases

Scientists investigating the interaction of a group of proteins in the brain responsible for protecting nerve cells from damage have identified a new target that could increase cell survival.

Meet the World's Most Advanced Brain Scanner

The super-MRI used in the Human Connectome Project is the ultimate brain hacking machine.

The Brain Rewires Itself After Damage Or Injury

When the brain's primary "learning center" is damaged, complex new neural circuits arise to compensate for the lost function, say life scientists from UCLA and Australia who have pinpointed the region...

Better Than Expected Long-Term Outcomes In Patients With Advanced Coronary Artery Disease

Death rates associated with patients with refractory angina, or chronic chest pain, are lower than previously considered; therefore, physicians should focus on relieving the chest pain symptoms and im...

For combat veterans suffering from post-traumatic stress disorder, 'fear circuitry' in the brain never rests

(NYU Langone Medical Center / New York University School of Medicine) Chronic trauma can inflict lasting damage to brain regions associated with fear and anxiety.

Danger signalling during cancer cell death: origins, plasticity and regulation

Death toll from new bird flu in China rises to 36: WHO

LONDON (Reuters) - Four more people in China have died from a new strain of bird flu, bringing the death toll from the H7N9 virus to 36 from 131 confirmed cases, the World Health Organization (WHO) sa...

Events [ 2 Associated Events listed on BioPortfolio]

European Lab Automation 2013

Translational CNS Summit

Increase the translational potential of your CNS therapies - Bridge the Translational Gap

Companies [ 99 Associated Companies listed on BioPortfolio]

Neuronix Ltd.

Established in 2008, Neuronix has developed a non-invasive technology-based treatment of brain conditions and their related symptoms, with a focus on Alzheimer's Disease (“AD...

Lumos Labs, Inc.

Lumos Labs is the cognitive neuroscience research and development company behind Lumosity.com, the #1 destination for healthy online brain training with over 7 million members. Th...

Impulse Monitoring, Inc. (IMI)

Impulse Monitoring, Inc. (IMI) provides surgical support services to hospitals and other facilities that includes intraoperative neuromonitoring (IONM) for spinal, nerve and brain...

Lumosity

With more than 11 million members, Lumosity is the leader in brain health and performance. Offering more than 40 games and assessments backed by science, Lumosity tools are clinic...

SurgiVision, Inc.

Founded in 1998, SurgiVision, Inc. is a leader in the emerging field of MRI-guided interventions, creating innovative platforms for performing the next generation of minimally inv...

MRI Interventions, Inc.

Founded in 1998, MRI Interventions, Inc. is creating innovative platforms for performing the next generation of minimally invasive surgical procedures in the brain and heart. Util...

Blaze Bioscience, Inc.

Blaze Bioscience, Inc. is a Seattle-based, privately-held biotechnology company dedicated to developing products that assist surgeons in their quest to improve the lives of cancer...

SAGE Therapeutics

SAGE Therapeutics is a central nervous system (CNS) product focused company building a portfolio of new therapies to meet the growing unmet need in a range of CNS disorders, inclu...

HealthRally

HealthRally is a social health company that has developed a crowdfunding platform that uses social motivation and positive financial incentives to inspire people to achieve their...

Velomedix, Inc.

Based in Menlo Park, California, Velomedix, Inc. is a development stage medical device company created to realize the clinical potential of mild Therapeutic Hypothermia in benefit...

Clinical Trials [ 2221 Associated Clinical Trials listed on BioPortfolio]

Positron Emission Tomography (PET) to Study Brain Signaling

This study uses positron emission tomography (PET) to examine brain function and signaling involving phospholipids, and to see how signaling is related to blood flow. Much of the brain is...

Brain Peripheral Benzodiazepine Receptors in Patients With Multiple Sclerosis

This study will use positron emission tomography (PET) to measure a brain protein called peripheral benzodiazepine receptor (PBR) in patients with multiple sclerosis. PBR is created during...

Progesterone for the Treatment of Traumatic Brain Injury

The ProTECT study will determine if intravenous (IV) progesterone (started within 4 hours of injury and given for a total of 96 hours), is more effective than placebo for treating victims...

Ventricular Arrhythmias in Uremic Cardiomyopathy

There is a certain gene called sarcoplasmic reticulum gene (SERCA2a), which is found in heart muscle. This gene is also found in blood vessels and skin tissue. When active this gene builds...

Duloxetine in Osteoarthritis (OA) Pain

This study aims to determine in people with knee Osteoarthritis (OA) if relief of pain after treatment with either duloxetine or placebo is associated with changes in brain anatomy.

Effects of Transcranial Magnetic Stimulation on Object Recognition

Background: - The brain has natural rhythms called brain waves. An electroencephalogram (EEG) can record these rhythms. When people identify the picture of a familiar object shown on a co...

Vemurafenib, Cetuximab, and Irinotecan in Advanced Solid Cancers

The goal of this clinical research study is to find the highest tolerable dose of vemurafenib that can be given in combination with cetuximab and irinotecan to patients with advanced cance...

A Phase I - II Safety Study of Filgrastim (Neupogen) to Improve Left Ventricular Function After Severe Acute Myocardial Infarction

The objective is to obtain initial information regarding the safety and efficacy of the use of Filgrastim in the setting of acute myocardial infarction. The secondary objectives are to ob...

Family Preparation Study For Withdrawal of Mechanical Ventilation From Their Family Member

Using the self-regulation theory, an intervention to prepare families for that experience was developed. This study will assess the impact of the intervention on a family’s evaluation of...

Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-Year Manometric Follow-Up

Small bowel involvement is still recognized to be associated with great morbidity and mortality in SSc patients, leading particularly to malabsorption and intestinal pseudo-obstruction. In...

Medical and Biotech [MESH] Definitions

Wasting Disease, Chronic

A transmissible spongiform encephalopathy (prion disease) of DEER and elk characterized by chronic weight loss leading to death. It is thought to spread by direct contact between animals or through environmental contamination with the prion protein (PRIONS).

Dynamin I

A subtype of dynamin found primarily in the NEURONS of the brain.

Dynamin Iii

A subtype of dynamin found expressed exclusively in the testis, lung and brain.

Viridans Streptococci

A large heterogeneous group of mostly alpha-hemolytic streptococci. They colonize the respiratory tract at birth and generally have a low degree of pathogenicity. This group of species includes STREPTOCOCCUS MITIS; STREPTOCOCCUS MUTANS; STREPTOCOCCUS ORALIS; STREPTOCOCCUS SANGUIS; STREPTOCOCCUS SOBRINUS; and the STREPTOCOCCUS MILLERI GROUP. The latter are often beta-hemolytic and commonly produce invasive pyogenic infections including brain and abdominal abscesses.

Receptor, Epha3

An eph family receptor that is found primarily in adult BRAIN and variety of tissues in the developing embryo tissues. During embryonic development high levels of EphA3 receptor expression is seen in the nervous system and coincides with neuronal cell migration, suggesting a role for this protein in axonal pathfinding.

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