Bulimia Nervosa - Biotech, Pharma and Life Science Channel
Bulimia is an illness characterized by the cycle of binging on food, guilty feelings and resultant purging (vomiting or laxative abuse) to counteract the previous binge. It is much more common in young girls and women.
The cause is thought to be multi-factorial; genetic, psychological, trauma, family, society, or cultural factors. Despite an often normal body weight, patients see themselves as overweight. The social obsession with physical form is thought to help trigger the condition.
The risks of bulimia include damage to teeth (gingivitis or enamel erosion), dehydration and may lead to anorexia and other serious conditions. Treatment includes support groups, CBT and antidepressant medications.
Source; Adapted from NIH
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PubMed Articles
Eating disorders is a prevalent, serious condition that affects, mainly young women. An early and enduring sign of anorexia is amenorrhea. There is no evidence for benefits of hormone therapy in patie...
OBJECTIVE: The aim of this pilot study was to test the acceptability and benefit of a guided self-help intervention incorporating a mobile component in eating disorders (EDs). METHOD: Eighteen people...
Treating eating disorders over the internet: A systematic review and future research directions.
OBJECTIVE: To review the literature regarding internet-based treatment of eating disorders (ED). METHOD: Relevant studies were identified by searching electronic databases (including Medline, Embase,...
OBJECTIVE: Anorexia nervosa (AN) has been associated with weak central coherence (CC) and weak set shifting (SS). The main aim of this study was to examine possible differences between restrictive AN...
Congestive heart failure as cause of death in an anorexia nervosa fatal case.
Background: The aim of this study is to compare the effectiveness of two exposure procedures on habituation of emotional responses to food stimuli: (a) exposure to external cues (food images) without...
We conducted four studies to examine the relationship between over-exercise and suicidality. Study 1 investigated whether over-exercise predicted suicidal behavior after controlling for other eating d...
Purging Disorder: A Comparison to Established Eating Disorders with Purging Behaviour.
This study is part of the larger Christina Barz Study, and it compared consecutively admitted patients with purging disorder (PurD; N = 225) with consecutively admitted patients with anorexia nerv...
OBJECTIVE: There are limited data supporting specific treatments for adults with anorexia nervosa (AN). Randomized clinical trials (RCTs) for adults with AN are characterized by high attrition limitin...
Reduced fasting plasma levels of diazepam-binding inhibitor in adolescents with anorexia nervosa.
OBJECTIVE: Altered expression and/or function, both peripherally and centrally, of various neuropeptides is involved in the neurophysiology of anorexia nervosa (AN). Diazepam-binding inhibitor (DBI) i...
News Articles
Anorexia and bulimia cases outnumbered by other eating disorders
Anorexia and bulimia may be the two most well known eating disorders but they are not the most common, a new study reveals.
The incidence of eating disorders is increasing in the UK
More people are being diagnosed with eating disorders every year and the most common type is not either of the two most well known—bulimia or anorexia—but eating disorders not otherwise specified...
Springer, SISDCA partner to publish scientific journal on eating disorders and obesity
Springer and the Italian Society for the Study of Eating Disorders (Societ- Italiana per lo Studio dei Disturbi del Comportamento Alimentare - SISDCA) have agreed to a five-year collaboration to publi...
Center for Discovery's Runyan Named Keynote Presenter at CAMFT Conference
Center for Discovery, a national leader in eating disorder treatment, has announced that James “Buck” Runyan, MS, LMFT, LPCC, clinical consultant at Center for Discovery, will be a keynote present...
Springer to collaborate with the Italian Society for the Study of Eating Disorders
(Springer) Springer and the Italian Society for the Study of Eating Disorders (Società Italiana per lo Studio dei Disturbi del Comportamento Alimentare - SISDCA) have agreed to a five-year collaborat...
Severe anorexia nervosa improves with modification of standard goals, treatment methods
A new, multinational randomized clinical trial has found that patients with severe and enduring anorexia nervosa will not only stick with treatments but also make significant improvements with just a...
Results Improved For Those With Persistent Anorexia By Rethinking Treatment Goals
A new, multinational randomized clinical trial has found that patients with severe and enduring anorexia nervosa will not only stick with treatments but also make significant improvements with just a...
Complication of pellagra in anorexia nervosa
bmj;346/may08_1/f2842/FIG1F1fig1A 16 year old girl presented to the emergency department with a low body mass index and skin changes. She was diagnosed with anorexia nervosa, and the skin changes......
Rethinking treatment goals improves results for those with persistent anorexia
(University of Chicago Medical Center) Patients with severe and enduring anorexia nervosa not only stuck with treatments in a clinical trial but also made significant improvements with just a slight m...
Valproate Migraine Drugs During Pregnancy Bad For Baby's IQ
Using migraine prevention valproate sodium drugs during pregnancy can cause offspring to have a lower IQ, the US Food and Drug Administration (FDA) warned yesterday. Sodium valproate is an anticonvuls...
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Companies
Eating Disorder Center of Denver
Established in 2001, Eating Disorder Center of Denver (EDCD) is one of the nation's foremost centers for the diagnosis and treatment of the full range of eating disorders. EDCD is...
Clinical Trials
A Double-Blind, Placebo Controlled Trial of Risperidone for the Treatment of Anorexia Nervosa
The aim of this pilot study is to determine the safety and efficacy of risperidone for the treatment of anorexia nervosa. Hypothesis 1: Subjects on risperidone will show a more significa...
Cortical Excitability in Obsessive-Compulsive and Related Disorders
This study will use transcranial magnetic stimulation (TMS) to study the function of the cerebral cortex (outer layer of the brain) in people with obsessive compulsive disorder (OCD) and r...
Evaluation and Follow-up of Individuals With Obsessive-Compulsive Disorder and Related Conditions
The purpose of this study is to better understand the long-term progress of people with obsessive-compulsive disorder (OCD) and related conditions such as anorexia nervosa, Tourette syndro...
This research examines the efficacy of a 5-session individual psychotherapy intervention designed to enhance readiness and motivation for change in individuals with anorexia nervosa, bulim...
Drug Transport in Patients With Anorexia Nervosa
The aim of this study is to investigate whether patients with anorexia nervosa have elevated plasma cholesterol levels and, if elevated plasma cholesterol levels influence drug transport b...
Bone Loss in Women With Anorexia Nervosa
Women with Anorexia Nervosa have been found to have low bone density. The study will determine whether administration of low doses of a natural hormone, testosterone and/or risedronate, a...
Effects of Anorexia Nervosa on Bone Mass in Adolescents
This study is to determine the effects of anorexia nervosa on bone mass and hormone levels in adolescents. Whether administration of estrogen, a normal hormone present during puberty, can...
Treatment of Binge Eating Disorder
This is a multicenter (2 sites) randomized trial evaluating three group treatment models for subjects with binge eating disorder. One model is a cognitive behavior treatment (CBT) group, o...
Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa
Adolescents with anorexia nervosa (AN) are at high risk for low bone mineral density at a time when healthy adolescents are rapidly accruing bone, with implications for peak bone mass and...
Group Parent Training for Adolescent Eating Disorders
While parents are considered essential for the effective treatment of adolescents with anorexia nervosa, the most effective manner to involve parents in treatment is unknown. Given reports...
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Medical and Biotech [MESH] Definitions
Bulimia Nervosa
An eating disorder that is characterized by a cycle of binge eating (BULIMIA or bingeing) followed by inappropriate acts (purging) to avert weight gain. Purging methods often include self-induced VOMITING, use of LAXATIVES or DIURETICS, excessive exercise, and FASTING.
Binge-eating Disorder
A disorder associated with three or more of the following: eating until feeling uncomfortably full; eating large amounts of food when not physically hungry; eating much more rapidly than normal; eating alone due to embarrassment; feeling of disgust, DEPRESSION, or guilt after overeating. Criteria includes occurrence on average, at least 2 days a week for 6 months. The binge eating is not associated with the regular use of inappropriate compensatory behavior (i.e. purging, excessive exercise, etc.) and does not co-occur exclusively with BULIMIA NERVOSA or ANOREXIA NERVOSA. (From DSM-IV, 1994)
Serotonin Uptake Inhibitors
Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behavior, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the ADRENERGIC UPTAKE INHIBITORS also inhibit serotonin uptake; they are not included here.
Kluver-bucy Syndrome
A neurobehavioral syndrome associated with bilateral medial temporal lobe dysfunction. Clinical manifestations include oral exploratory behavior; tactile exploratory behavior; hypersexuality; BULIMIA; MEMORY DISORDERS; placidity; and an inability to recognize objects or faces. This disorder may result from a variety of conditions, including CRANIOCEREBRAL TRAUMA; infections; ALZHEIMER DISEASE; PICK DISEASE OF THE BRAIN; and CEREBROVASCULAR DISORDERS.
Anorexia
The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
