Cardiac Imaging Tests - Biotech, Pharma and Life Science Channel
PubMed Articles
Novel aspects of excitation-contraction coupling in heart failure.
Excitation-contraction coupling is the process by which electrical activation is translated into contraction of a cardiac myocyte and thus the heart. In heart failure, expression, phosphorylation, and...
The heart contains various types of cells, including cardiomyocytes, cardiac fibroblasts, many kinds of immune cells and vascular cells. Initial studies mainly focused on cardiomyocytes, which directl...
SIRT1 mediates the protective function of Nkx2.5 during stress in cardiomyocytes.
Nkx2.5 plays protective roles in cardiac homeostasis and survival in the postnatal hearts. However, the underlying molecular mechanisms that mediate the protective functions of Nkx2.5 remain unknown....
Brainstem auditory evoked potentials and somatosensory evoked potentials in Chiari malformation.
INTRODUCTION. Chiari malformations (CM) include a series of congenital anomalies involving the descent of the cerebellar tonsils below the foramen magnum, which may be associated with compression in t...
Objective-To investigate cardiovascular changes and survival times following complete interventional device occlusion of uncomplicated left-to-right shunting patent ductus arteriosus in dogs. Design-R...
Interobserver agreement and diagnostic accuracy of brain magnetic resonance imaging in dogs.
Objective-To evaluate interobserver agreement and diagnostic accuracy of brain MRI in dogs. Design-Evaluation study. Animals-44 dogs. Procedures-5 board-certified veterinary radiologists with variable...
Diagnostic imaging in veterinary dental practice.
Synthesis and application of cNGR-containing imaging agents for detection of angiogenesis.
Angiogenesis is a multi-step process regulated by pro- and anti-angiogenic factors. Inhibition of angiogenesis is a potential anti cancer treatment strategy that is now investigated clinically. In add...
Dry stacking of wastewater treatment sludges.
Drying pans are used during wastewater treatment (WWT) to store, stabilise and dry residual solids. The pans are filled with sludge that dries via exposure to sunshine and wind. We propose that drying...
In vivo imaging of brain metabolism activity using a phosphorescent oxygen-sensitive probe.
Several approaches have been adopted for real-time imaging of neural activity in vivo. We tested a new cell-penetrating phosphorescent oxygen-sensitive probe, NanO2-IR, to monitor temporal and spatial...
News Articles
Unexplained deaths spark FDA probe of Lilly's Zyprexa Relprevv
High doses of olanzapine can cause delirium, cardiopulmonary arrest, cardiac arrhythmias and reduced level of consciousness ranging from sedation to coma, the agency said in a MedWatch alert to health...
Increased Risk Of Prostate Cancer In Human Stem Cells Following Exposure To Low Doses Of BPA
Exposing developing tissue to low levels of the plastic bisphenol A, commonly known as BPA, is linked to a greater incidence of prostate cancer in tissue grown from human prostate stem cells, a new st...
Invivoscribe FLT3 Testing Patents Strengthened by Supreme Court Ruling
SAN DIEGO, CA -- (Marketwired) -- 06/19/13 -- In Association of Molecular Pathology v. Myriad, the U.S. Supreme Court struck down BRCA1 and BRCA2 gene patent claims. It is important for the diagnosti...
CAMBRIDGE, MA -- (Marketwired) -- 06/19/13 -- Sarepta Therapeutics, Inc. (NASDAQ: SRPT), a developer of innovative RNA-based therapeutics, today announced updated data from Study 202, a Phase IIb ope...
The Health Checkup Was It Ever Effective? Could It Be Effective?
In this issue of JAMA, the JAMA Clinical Evidence Synopsis by Krogsbøll et al summarizes a systematic review of 9 randomized trials of a general health check. A general health check is defined as hea...
ImportanceInjection of contaminated methylprednisolone has resulted in an unprecedented nationwide outbreak of Exserohilum rostratum fungal infections, manifested initially as meningitis and/or basila...
Opinion: Perspectives on imaging in axial spondyloarthritis
Imaging is central for the classification and diagnosis of axial spondyloarthritis, as well as for monitoring disease progression and predicting response to treatment. Xenofon Baraliakos and Jürgen B...
Protein Being Studied To Fight Cancer; May Cause Toxicity In Cardiac Cells
A study by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences and the Department of Pharmacology at the University of California, San Diego, shows that a protein called MCL-1, which...
Events
Companies
Royal Philips (NYSE: PHG, AEX: PHIA) is a diversified health and well-being company, focused on improving peopleâs lives through meaningful innovation in the areas of Healthc...
Overlake Hospital Medical Center is a nonprofit, non-tax-supported regional medical center with a network of medical clinics throughout the Eastside. The hospital is licensed for...
A privately-owned business located in Louisville, Kentucky, PGXL Laboratories was the first lab in the country CLIA-certified specifically to conduct pharmacogenetic tests. It offers pharmacogenetic t...
EPIR Technologies, Inc. is a fast growing high-technology company based in Bolingbrook, Illinois. Dr. Sivananthan, director of the Microphysics Laboratory at the University of Ill...
Daylight Solutions develops molecular detection, imaging and high-power illumination systems for use in industrial process controls, scientific research, medical diagnostics, envi...
Headquartered in suburban Philadelphia, CardioReady is an innovative company committed to improving survival from Sudden Cardiac Arrest. With a team comprised of professi...
Greatbatch, Inc. (NYSE: GB) provides critical technologies to industries that depend on reliable, long lasting performance through its brands Greatbatch Medical and Electrochem. G...
Anthem Blue Cross and Blue Shield Foundation
Through charitable grant making, the Anthem Blue Cross and Blue Shield Foundation LLC, an independent licensee of the Blue Cross and Blue Shield Association, promotes Anthemâ...
NeuroVision Imaging, LLC (www.neurovision.com) was formed in 2010 and is headquartered in Sacramento, California. The Company develops digital imaging, and diagnostic solutions fo...
Based in Brisbane, California, XDx is a molecular diagnostics company focused on the discovery, development and commercialization of noninvasive gene expression-based tests for th...
Clinical Trials
Brain Peripheral Benzodiazepine Receptors in Patients With Multiple Sclerosis
This study will use positron emission tomography (PET) to measure a brain protein called peripheral benzodiazepine receptor (PBR) in patients with multiple sclerosis. PBR is created during...
Neuropsychological and Behavioral Testing in Young Patients With Cancer
This clinical trial is studying neuropsychological and behavioral testing in young patients with cancer. Collecting information over time from a series of tests may help doctors develop ef...
Real Time Optical Coherence Tomography (OCT) of Human Tissue
This is a single-arm, prospective, study of an optical imaging device on approximately twenty (20) subjects undergoing lumpectomies at one study site. In vivo and ex vivo imaging will be p...
Navigation of the Pelvic Floor in Bladder Exstrophy Using Pre-operative MRI
The aim of this study is to investigate the use of intraoperative stereotactic imaging of the pelvic floor musculature during closure of bladder exstrophy.
Left Atrial Appendage Occlusion Study II
A pilot, multicentre randomized controlled study of surgical left atrial occlusion (LAA) in 50 patients with atrial fibrillation/flutter undergoing cardiac surgery requiring cardiopulmonar...
89Zr-trastuzumab PET for Imaging the Effect of HSP90 Inhibition
HSP90 inhibition is a potentially new targeted drug modality in the treatment of HER2 positive, trastuzumab refractory breast cancer. Little is known about the pharmacodynamics of HSP90 in...
Screening Evaluation for Women With Postpartum Depression
This study evaluates the relationship between mood changes and hormones in women with postpartum depression (PPD). This is an observational study; volunteers who participate will not rece...
Positron Emission Tomography (PET) to Study Brain Signaling
This study uses positron emission tomography (PET) to examine brain function and signaling involving phospholipids, and to see how signaling is related to blood flow. Much of the brain is...
This study will evaluate whether the drug mifepristone can improve the symptoms of Cushing's syndrome in people with ectopic adrenal corticotrophin hormone (ACTH) secretion. Cushing's synd...
Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression
Background: - Atherosclerosis (thickening of the artery walls caused by cholesterol and other deposits) commonly occurs in the heart vessels and carotid (neck) arteries of adults. This i...
Videos
Nuclear Cardiac Imaging Camera - The Nebraska Medical Center
Nuclear cardiac imaging gives Nebraska Medical Center doctors new and better ways to see a patient's heart and how it is working. The camera at the UNMC Phys...
Medical and Biotech [MESH] Definitions
Muscle Cells
Mature contractile cells, commonly known as myocytes, that form one of three kinds of muscle. The three types of muscle cells are skeletal (MUSCLE FIBERS, SKELETAL), cardiac (MYOCYTES, CARDIAC), and smooth (MYOCYTES, SMOOTH MUSCLE). They are derived from embryonic (precursor) muscle cells called MYOBLASTS.
Myocytes, Cardiac
Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).
Myoblasts, Cardiac
Precursor cells destined to differentiate into cardiac myocytes (MYOCYTES, CARDIAC).
Myoblasts
Embryonic (precursor) cells of the myogenic lineage that develop from the MESODERM. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes (MYOCYTES, SKELETAL; MYOCYTES, CARDIAC; MYOCYTES, SMOOTH MUSCLE).
Erysimum
A plant genus of the family BRASSICACEAE. Some members contain CARDIAC GLYCOSIDES.