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Cardiac response - Biotech, Pharma and Life Science Channel

18:54 EDT 19th May 2013 | BioPortfolio

PubMed Articles [ 10201 Associated PubMed Articles listed on BioPortfolio]

Evidence for predictive role of BRCA1 and bTUBIII in gastric cancer.

Sensitivity of gastric cancer (GC) to conventional cytotoxic therapy may be at least in part attributed to molecular features of the tumor cells. We analyzed all patients with metastatic GC treated in...

Correction of hypocalcemia allows optimal recruitment of FGF-23-dependent phosphaturic mechanisms in acute hyperphosphatemia post-phosphate enema.

Both parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23) are phosphaturic hormones. These hormones should increase in response to phosphate excess. However, they also regulate serum calc...

Managing Cardiotoxicity of Chemotherapy.

OPINION STATEMENT: The increase in survivorship of cancer patients makes the understanding of the available options for prevention and treatment of cardiotoxicity induced by antineoplastic agents a cr...

Cardiac myxosarcoma with thoracic spinal metastasis.

Echocardiography revealed a left atrial tumor in a 59-year-old man with back pain that concurrently worsened with left foot drop and loss of the left ankle reflex soon after admission to our hospital....

Use of pharmacogenetics for predicting cancer prognosis and treatment exposure, response and toxicity.

Cancer treatment is complicated because of a multitude of treatment options and little patient-specific information to help clinicians choose appropriate therapy. There are two genomes relevant in can...

Proteomic Analysis of the Oxidative Stress Response Induced by Low-Dose Hydrogen Peroxide in Bacillus anthracis.

Anthrax is a bacterial disease caused by the aerobic sporeforming bacterium Bacillus anthracis, which is an important pathogen owing to its ability to be used as a terror agent. B. anthracis spores ca...

Non-invasive assessment of cardiac function in a mouse model of renovascular hypertension.

Hypertension continues to be a significant cause of morbidity and mortality, underscoring the need to better understand its early effects on the myocardium. The aim of this study is to determine the f...

EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2.

MicroRNAs (miRNAs) are generated by two-step processing to yield small RNAs that negatively regulate target gene expression at the post-transcriptional level. Deregulation of miRNAs has been linked to...

Reduced Caveolin-1 Promotes Hyperinflammation due to Abnormal Heme Oxygenase-1 Localization in Lipopolysaccharide-Challenged Macrophages with Dysfunctional Cystic Fibrosis Transmembrane Conductance Regulator.

We have previously reported that TLR4 signaling is increased in LPS-stimulated cystic fibrosis (CF) macrophages (MΦs), contributing to the robust production of proinflammatory cytokines. The heme oxy...

Efficacy and safety of transulnar coronary angiography and interventions - a single center experience.

OBJECTIVES: To evaluate the efficacy and long term safety of transulnar approach in complex coronary interventions. BACKGROUND: The success rate of transulnar approach in complex coronary intervention...

News Articles [ 5966 Associated News Articles listed on BioPortfolio]

Spontaneous brain activity in amygdala higher among combat veterans with PTSD

Chronic trauma can inflict lasting damage to brain regions associated with fear and anxiety. Previous imaging studies of people with post-traumatic stress disorder, or PTSD, have shown that these brai...

New Implantable Defibrillator Could Save Lives

A new kind of implantable cardiac defibrillator may save lives. One cardiac patient shares his story.

Why the Precautionary Principal is a Crock. Speed Matters when it comes to Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

VACCINES Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

News and press releases: European Medicines Agency recommends first vaccine for foot-and-mouth disease for authorisation at EU level

The European Medicines Agency’s Committee for Medicinal Products for Veterinary Use (CVMP) has recommended the marketing authorisation for Aftovaxpur DOE for use in response to outbreaks of foot-and...

ECMO may show promise as rescue strategy for select cardiac arrest patients

Extracorporeal membrane oxygenation, a procedure traditionally used during cardiac surgeries and in the ICU that functions as an artificial replacement for a patient's heart and lungs, has also been u...

Free fatty acids linked to cardiac risk in late adulthood

(HealthDay)—Blood levels of free fatty acids are associated with insulin resistance during young adulthood and cardiovascular risk factors in later adulthood, according to a study published online M...

Pacemakers Could Be Hacked, Researchers Claim, But Not Easily

redOrbit Staff & Wire Reports - Your Universe Online The sensors used by implanted cardiac defibrillators and pacemakers to detect the rhythm of a person’s beating heart are vulnerable to compu...

DNA variant affects diabetes risk and treatment response

A DNA variant near a digestive enzyme does not only affect risk of developing diabetes but also affects the response to treatment, an international consortium of researchers including the University o...

Loyola University Health System creates new weapon to fight against obesity

In the past 30 years the number of children living in the U.S. who are obese has more than doubled and the number of adolescents has tripled. In response, Loyola University Health System has created a...

Infection And Sepsis-Related Mortality Hotspots Identified Across The US

In the past, researchers have sought to determine the geographic distribution of many life-threatening conditions, including stroke and cardiac arrest. Now, researchers at the Perelman School of Medic...

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Companies [ 200 Associated Companies listed on BioPortfolio]

IDS Ltd

From its establishment in 1977, simply as a Distributor of diagnostic products, IDS has become a globally-recognised innovator and marketeer in the IVD industry.The Company is particularly well-known...

BioNova - The Nova Scotia Biotechnology and Life Sciences Industry Association

BioNova was incorporated in 1993 in response to rapid growth in Nova Scotia’s biotechnology and life sciences sector. Since that time, we have advanced alongside our members to offer advocacy and de...

MedStar Washington Hospital Center

MedStar Heart Institute, headquartered at MedStar Washington Hospital Center, is a national leader in the research, diagnosis and treatment of cardiovascular disease, and has been...

Heart Rhythm Society

The Heart Rhythm Society is the international leader in science, education and advocacy for cardiac arrhythmia professionals and patients, and the primary information resource on heart rhythm disorder...

Dendreon Corporation

Dendreon Corporation is a biotechnology company whose mission is to target cancer and transform lives through the discovery, development, commercialization and manufacturing of no...

OpenSpan, Inc.

OpenSpan provides technology and services that improves, accelerates and measures software- and data-driven work on the desktop, driving performance in front-office and back-offic...

Spaulding Clinical

Spaulding Clinical (www.spauldingclinical.com) is a Phase 1 Clinical Pharmacology Research Unit and Electrocardiography Core Lab located in West Bend, Wisconsin offering a full ra...

Reliant Healthcare Professionals, Inc.

Based in Greenwood Village, Colorado, Reliant Healthcare Professionals, Inc. is a premier provider of rapid-response nurse staffing services, operating as FASTAFF Travel Nu...

DecImmune Therapeutics

DecImmune Therapeutics was founded by Michael Carroll PhD (The Immune Disease Institute, Harvard Medical School), and Francis Moore Jr. MD (Brigham and Women’s Hospital, Harv...

Reichert Technologies

With a history of over 150 years, Reichert Inc., of Buffalo, NY, continues to be a global leader in the design and manufacture of high-quality diagnostic instruments and equipment...

Clinical Trials [ 2316 Associated Clinical Trials listed on BioPortfolio]

Left Atrial Appendage Occlusion Study II

A pilot, multicentre randomized controlled study of surgical left atrial occlusion (LAA) in 50 patients with atrial fibrillation/flutter undergoing cardiac surgery requiring cardiopulmonar...

Efficacy and Safety of Short Course Therapy With Peginterferon Alpha-2b (PEG-IFN Alfa-2b) and Ribavirin (RBV) for Chronic Hepatitis C (Genotype 4) Participants Achieving a Rapid Virological Response at Week 4 of Treatment (MK-8908B-059 AM1)

The purpose of this study is to assess the efficacy of a short course of therapy (24 weeks) versus standard 48 week treatment in previously untreated adult participants with chronic hepati...

Quetiapine in Melancholic Depression

In summary, the investigators propose to integrate fMRI assessments within a clinical trial of quetiapine XR in patients with melancholic depression in order to test the predictions that:...

Docetaxel and Capecitabine for First Line Treatment of Metastatic Squamous Cell Carcinoma of the Head & Neck

Recent progress in treatment of recurrent/metastatic SCCHN has been made with the introduction of the taxanes. Docetaxel as a single agent has a response rate of 22-42% and 17% in patients...

Phase III Randomized Trial of Thalidomide/Dexamethasone vs VAD.

This study compares the response rate, overall response rate and survival of patients with multiple myeloma when randomized to two regimens (thalidomide+Dexamethasone vs. Vincristine+Adria...

HRN 004- Peginterferon a-2a Plus Ribavirin for Chronic Hepatitis C Infection in HIV Infected Persons Who Have Failed to Achieve a Sustained Virologic Response Following Previous Interferon Therapy

Objectives: Primary To evaluate the safety, tolerability, and efficacy of Peginterferon a-2a plus Ribavirin for the treatment of chronic hepatitis C (CHC) infection in persons co-infected...

Measurement of Angiogenic Related Growth Factors in Urine and Blood From Patients With Pulmonary Vein Stenosis

Prospective, single center, descriptive study in 14 infants/children with multivessel pulmonary vein stenosis stratified for patients with or without underlying cardiac disease. Group 1:...

"Salvage Use" of Recombinant Factor VIIa After Inadequate Haemostasis in Complex Cardiac Surgery

Aims and Hypotheses: This randomised placebo controlled study will test the hypothesis that Recombinant Activated Factor VII (rVIIa) will improve haemostasis after an inadequate response...

Clonidine and Left Ventricular Dysfunction

The objectives of this study are: 1. To evaluate the effect of clonidine, a sympathetic modulator, to reverse cardiac remodeling and to improve hemodynamics in diastolic heart fail...

Gene Expression Profiling in PBMCs as a Tool for Prediction of Infliximab Responsiveness in Rheumatoid Arthritis

The objective of the study is to identify and validate predictive markers of infliximab responsiveness in RA patients by 2 approaches: i) measuring biochemical, immunological and bone mark...

Medical and Biotech [MESH] Definitions

Muscle Cells

Mature contractile cells, commonly known as myocytes, that form one of three kinds of muscle. The three types of muscle cells are skeletal (MUSCLE FIBERS, SKELETAL), cardiac (MYOCYTES, CARDIAC), and smooth (MYOCYTES, SMOOTH MUSCLE). They are derived from embryonic (precursor) muscle cells called MYOBLASTS.

Myocytes, Cardiac

Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).

Myoblasts, Cardiac

Precursor cells destined to differentiate into cardiac myocytes (MYOCYTES, CARDIAC).

Myoblasts

Embryonic (precursor) cells of the myogenic lineage that develop from the MESODERM. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes (MYOCYTES, SKELETAL; MYOCYTES, CARDIAC; MYOCYTES, SMOOTH MUSCLE).

Erysimum

A plant genus of the family BRASSICACEAE. Some members contain CARDIAC GLYCOSIDES.

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