Cellular and Molecular Basis of Cancer - Biotech, Pharma and Life Science Channel
PubMed Articles
Clinical significance of tumor cavitation (TC) prior to and following first-line chemotherapy of lung cancer is unclear. An evaluation of the incidence and prognostic role of TC among treatment naive...
Antisense oligonucleotides (oligos) have been employed against prostate cancer models in both in vivo and in vitro systems. While most target growth factors or their receptors, other oligos are direct...
Prognostic value of TMPRSS4 expression in patients with breast cancer.
Transmembrane protease, serine 4 (TMPRSS4), is a novel type II transmembrane serine protease that is highly expressed on the cell surface in pancreatic, thyroid, lung, and other cancer tissues, althou...
Breast cancer is the most common cancer in women worldwide. The disease remains a public health concern as recent evidence indicates that the breast cancer burden has increased mainly in developing an...
Expression and prognostic significance of GATA-binding protein 2 in colorectal cancer.
GATA-binding protein 2 (GATA2) is a nuclear transcription factor that plays a critical role in tumorigenesis. High levels of GATA2 expression are correlated with poor survival outcomes in many types o...
Clinical significance of serum adipokines levels in lung cancer.
Adipokines have a significant effect on metabolism, immunoinflammatory responses as well as on carcinogenesis; therefore, we aimed at evaluating their potential predictive and prognostic significance...
p73 gene shares structural and functional similarities to p53 and plays an important role in modulating cell cycle arrest and apoptosis. A common non-coding polymorphism of p73 G4C14-to-A4T14 (rs22739...
Prognostic value of proliferation markers expression in breast cancer.
In this study, immunohistochemical expression of five proliferation markers: Ki-67, aurora-A kinase, survivin, B-Myb and cyclin B1, was analyzed. Consecutive 215 tumor samples from breast cancer patie...
Clinical implications of CIP2A protein expression in breast cancer.
The aim of this work is to study the expression and regulatory effects of CIP2A protein in breast cancer and the correlation between CIP2A protein expression and the prognosis of breast cancer. The CI...
CYP2A6, CYP1A1, and CYP2D6 polymorphisms in lung cancer patients from Central South China.
Lung cancer is a common cause of cancer-related death. The link between risk of lung cancer susceptibility and genetic polymorphisms in metabolic enzymes is well documented. In this study, the relatio...
News Articles
OncoGenex Announces Multiple 'Trials in Progress' Presentations at the 2013 ASCO Annual Meeting
BOTHELL, Wash. and VANCOUVER, British Columbia, May 22, 2013 /PRNewswire/ -- OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI), a leader in the development of novel therapeutics to target mechanisms...
Obesity directly tied to several cancers
"Obesity is a major risk factor for developing cancer, roughly the equivalent of tobacco use, and both are potentially reversible. Further, obese cancer patients do worse in surgery, with radiation or...
LOS ANGELES, May 22, 2013 /PRNewswire/ -- Kathy Ireland, CEO and Chief Designer of kathy ireland Worldwide (kiWW) and leading women's health advocate, and world-renowned board certified surg...
Final NICE no for Avastin in ovarian cancer
Final NICE no for Avastin in ovarian cancer
Making gold nanoparticles more effective against ovarian cancer cells
Positively charged gold nanoparticles are usually toxic to cells, but cancer cells somehow manage to avoid nanoparticle toxicity. Mayo Clinic researchers found out why and determined how to make the n...
LDCT helps identify earliest stages of lung cancer
A study of veterans at high risk for developing lung cancer shows that low-dose computed tomography can be highly effective in helping clinicians spot tiny lung nodules which, in a small number of pat...
Roche, Bristol-Myers, Merck drugs aim at lung cancer
A new class of experimental drugs shown to shrink tumors by unleashing the immune system are beginning to attract notice for one of the greatest unmet needs in oncology: treatment of lung cancer. Ro...
Findings suggest that a prosaposin-based drug could block metastasis spread
By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that...
Objective To assess the cancer risk in children and adolescents following exposure to low dose ionising radiation from diagnostic computed tomography (CT) scans.Design Population based, cohort, data.....
On May 22, 2013, the National Institute for Health and Care Excellence (NICE) published guidance on bevacizumab in combination with gemcitabine and carboplatin for treating the first recurrence of pla...
Events
Cancer Vaccines will provide attendees with a complete view of the cancer immunotherapy field. Focusing on the discovery of new vaccines, developments in target identification
SELECTBIO CellTech2014 will feature an integrated program of tracks designed to fully describe the latest trends in analysis of cells, cell-based assays, and high-content phenotypic assays.
Welcome to Molecular Medicine Congress and exhibition.
Stem Cells & Cell Therapy Summit
Select Biosciences' Stem Cells & Cell Therapy Summit is focused on providing an up-to-date expansive view of the current marketplace
Exosomes and Circulating Biomarkers Summit
Select Biosciences' Inaugural Exosomes and Circulating Biomarkers 2013 Summit Focuses on Cutting-Edge Science and Presentations from Academic and Industrial Researchers.
Pharmaceutical industry is utilizing a plethora of novel approaches, techniques and technologies for Drug Design and Discovery.
Select Bio is pleased to present the 3rd Screening Asia conference, which will take place at the Biopolis, Singapore, on November 12th & 13th
3rd Annual Oncology Biomarkers Congress 2013
Over 150 oncology focused industry delegates Over 50 presentations/roundtables/panel discussions
3rd World Congress on Cancer Science & Therapy
3rd world congress on Cancer Science & Therapy serves as a reunion land for scientists in the area of cancer research.
Companies
LABS, Inc., founded in 1979 as Immunological Associates of Denver, was one of the first transplant laboratories established in the United States. Today, as a taxable, non-profit c...
Ambry Genetics is a CAP-accredited, CLIA-certified commercial clinical laboratory headquartered in Aliso Viejo, California. Since the company's inception in 2000, it has become a leader in provi...
The Multiple Myeloma Research Foundation
Multiple myeloma is an incurable blood cancer. The five-year relative survival rate for multiple myeloma is approximately 34 percent, one of the lowest of all cancers. In 2009, ap...
Transgene (NYSE-Euronext: TNG), a member of the Institut Mérieux Group, is a biopharmaceutical company. It creates, develops and manufactures targeted immunotherapeutics for th...
TRANSGENE is a leading integrated gene therapy company, dedicated to the discovery and development of gene delivery technologies and gene therapy products for the treatment of acquired and inherited d...
American Cancer Society Cancer Action Network
The American Cancer Society combines an unyielding passion with nearly a century of experience to save lives and end suffering from cancer. As a global grassroots force of more th...
Loma Linda University Medical Center
Loma Linda University Medical Center (LLUMC), a Seventh-Day Adventist institution, is among the largest private medical educational centers in the United States and the only one in inland Southern...
Bio-Path is developing a patented, liposomal drug delivery system and products developed at The University of Texas M. D. Anderson Cancer Center, with two clinical cancer drug can...
Cancer Genetics, Inc. (CGI) is an emerging leader in the field of personalized medicine, offering products and services that enable cancer diagnostics as well as treatments that are tailored to the...
Foundation Medicine is dedicated to the development of comprehensive tests that will help physicians personalize cancer treatment for their patients. Foundation Medicineâs la...
Clinical Trials
Cell Lines From High-Risk Breast Tissue
Background: - Many risk factors for breast cancer have been identified, including family history, endocrine background, changes in breast tissue, cancer in one breast, radiation...
Immune Response to Hepatitis C Virus
This study will identify and characterize immune factors involved in hepatitis C infection and elimination of the virus. Individual responses to hepatitis C infection vary; some people ar...
Exercise and Metformin in Colorectal and Breast Cancer Survivors
Metformin is a medication that is commonly used in the treatment of diabetes. Recently small studies in cancer patients without diabetes suggest that metformin may benefit in lowering ins...
This prospective, multi-center, non-interventional study will evaluate the efficacy and safety of Herceptin (trastuzumab) in routine clinical practice in Chinese patients with gastric or g...
Phase 2A Study of NPC-1C Chimeric Monoclonal Antibody to Treat Pancreatic and Colorectal Cancer
The purpose of the phase 2A component of this study is to determine if giving the immune molecule NPC-1C to individuals who have cancer of the pancreas or gastrointestinal tract (colon or...
Neoadjuvant Axitinib in Prostate Cancer
The goal of this clinical research study is learn if adding axitinib to hormonal therapy can help to control prostate cancer when given before surgery. The safety of this drug will also be...
Testing the Helpfulness of 2 Decision Aids for Prostate Cancer
The purpose of this study is to test different methods for communicating information about prostate cancer treatment to men. The investigators are studying how best to present information...
Collecting and Storing Tissue Samples From Women With or Without Breast Cancer
RATIONALE: Collecting and storing samples of tissue, blood, and urine from patients with or without breast cancer to study in the laboratory may help the study of cancer. PURPOSE: This re...
Vemurafenib, Cetuximab, and Irinotecan in Advanced Solid Cancers
The goal of this clinical research study is to find the highest tolerable dose of vemurafenib that can be given in combination with cetuximab and irinotecan to patients with advanced cance...
Goserelin and Anastrozole in Treating Men With Recurrent or Metastatic Breast Cancer
RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using goserelin and anastrozole may fight breast cancer by blocking the use of estrogen by the tumor cells....
Videos
7.4. Molecular Basis of Cancer - Robbins Pathology Audiobook
Other chapters here- http://goo.gl/xsjkM Check out our channel for other sections- http://youtube.com/MedAudioBooks This is an audio version of the famous pa...
Medical and Biotech [MESH] Definitions
Nucleoside Transport Proteins
Proteins involved in the transport of NUCLEOSIDES across cellular membranes.
Nucleotide Transport Proteins
Proteins involved in the transport of NUCLEOTIDES across cellular membranes.
Dynamins
A family of high molecular weight GTP phosphohydrolases that play a direct role in vesicle transport. They associate with microtubule bundles (MICROTUBULES) and are believed to produce mechanical force via a process linked to GTP hydrolysis. This enzyme was formerly listed as EC 3.6.1.50.
Rna Transport
The process of moving specific RNA molecules from one cellular compartment or region to another by various sorting and transport mechanisms.
Mastocytosis, Systemic
A group of disorders caused by the abnormal proliferation of MAST CELLS in a variety of extracutaneous tissues including bone marrow, liver, spleen, lymph nodes, and gastrointestinal tract. Systemic mastocytosis is commonly seen in adults. These diseases are categorized on the basis of clinical features, pathologic findings, and prognosis.
