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Chronic Kidney Disease - Biotech, Pharma and Life Science Channel

17:13 EDT 25th May 2013 | BioPortfolio

PubMed Articles [ 16529 Associated PubMed Articles listed on BioPortfolio]

Temsirolimus controlled metastatic advanced renal cell carcinoma for over 4 years: a case study.

We present a case report of long-term response with temsirolimus in cytokine refractory metastatic renal cell carcinoma (RCC). A 74-year-old Japanese man was diagnosed with advanced RCC in November 20...

Treatment for hepatitis C virus-induced portal hypertension in leukemic children.

Children with acute leukemia are at high risk of hepatitis C infection, either by immunosuppression secondary to chemotherapy or by multiple transfusions of blood products during the course of the dis...

High CD74 expression correlates with ZAP70 expression in B cell chronic lymphocytic leukemia patients.

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults in Western countries. It is characterized by heterogeneous clinical course of the disease and new prognostic factors are still...

(1)H NMR-based metabonomic analysis of the serum and urine of rats following subchronic exposure to dichlorvos, deltamethrin, or a combination of these two pesticides.

Metabonomic analysis, clinical chemical analysis and histopathology were used to investigate the toxic effects of subchronic exposure to dichlorvos, deltamethrin, and a combination of these two pestic...

Methylenetetrahydrofolate reductase C677T variant in Moroccan patients with inflammatory bowel disease.

The association of genetic polymorphisms related to metabolism of homocysteine and folate with inflammatory bowel disease has been evidenced. Several studies have identified genetic variants of MTHFR...

Characteristics of polyomavirus BK (BKPyV) infection in primary human urothelial cells.

High-level polyomavirus BK (BKPyV) replication in urothelial cells is a hallmark of polyomavirus-associated hemorrhagic cystitis (PyVHC), a painful condition affecting bone marrow transplant recipient...

Index of microvascular resistance: A new effective tool to explore microvascular disease correlated with myocardial ischemia in diabetic patients without significant coronary artery disease.

Animal models of organic heart valve disease.

Heart valve disease is a frequently encountered pathology, related to high morbidity and mortality rates in industrialized and developing countries. Animal models are interesting to investigate the ca...

Novel devices and specialized techniques in recanalization of peripheral artery chronic total occlusions (CTOs) - A literature review.

Currently, recanalization of chronic total occlusions (CTOs) in peripheral arteries remains a challenging obstacle encountered by clinical practitioners. Percutaneous CTO interventions are associated...

Beta-blocker prevents sudden cardiac death in patients with hemodialysis.

Beta blockers were shown to prevent SCD in cardiomyopathy or coronary artery disease patients. Dialysis patients show elevated mortality rates, predominantly due to cardiovascular disease. SCD is now...

News Articles [ 12516 Associated News Articles listed on BioPortfolio]

Men With Afflicted Illnesses Must Know What to Expect from Prostate Surgeries while Dr. Allen’s Device Reverses BPH Naturally, Highlights Fine Treatment

Researchers have found that men with slower-growing forms of cancer and with three or more other serious illnesses, such as heart disease, diabetes, and hypertension, are far more likely to die from o...

Hidden Dangers Dog Dog Parks

SATURDAY, May 25 (HealthDay News) -- Many viruses and parasites that affect both dogs and humans, such as rabies and leptospirosis -- a bacteria-borne illness than can result in liver or kidney failur...

In The Most Severe Form Of Rheumatoid Arthritis, Enzyme-Activating Antibodies Identified As A Marker

In a series of lab experiments designed to unravel the workings of a key enzyme widely considered a possible trigger of rheumatoid arthritis, researchers at Johns Hopkins have found that in the most s...

How The Immune System Peacefully Co-Exists With 'Good' Bacteria

The human gut is loaded with commensal bacteria - "good" microbes that, among other functions, help the body digest food. The gastrointestinal tract contains literally trillions of such cells, and yet...

Anti-Cancer Drug Reverses Alzheimer's Disease In Mice

An anti-cancer drug may reverse memory problems in an Alzheimer's Disease mouse model, according to new research carried out at the University of Pittsburgh Graduate School of Public Health. The study...

The Genetic Basis Of Six Autoimmune Diseases Investigated By Researchers

Researchers from Queen Mary, University of London have led the largest sequencing study of human disease to date, investigating the genetic basis of six autoimmune diseases. The exact cause of these d...

Doctor Eiman Firoozmand Receives America’s Top Surgeon Award 2013 from Consumer’s Research Council of America

Eiman Firoozmand M.D., of Los Angeles Colon and Rectal Surgical Associates, has been presented with the Consumer’s Research Council of America Top Surgeon Award. Beverly Hills, CA (PRWEB) May 24, 20...

Certain chronic pain may raise suicide risk

NEW YORK (Reuters Health) - Back pain, migraine and other types of chronic pain without a known physical cause - and therefore little prospect for relief - were associated with an increased risk of su...

Modeling tumor–host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy

[Jennerex] closes $21.6mm late round

In what appears to be its Series F round, [Jennerex Biotherapeutics Inc.] (vaccinia-based cancer vaccines) has raised $21.6mm from undisclosed investors. Since inception, the company has raised over $...

Events [ 4 Associated Events listed on BioPortfolio]

The Economist Events - Healthy Europe Summit June 20th 2013

From sick care to health care

Diabetes: Secondary Complications, Regulation and Innovation Conference

SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.

AgriGenomics World Congress

Welcome to AgriGenomics World Congress 2013.

14th INTERNATIONAL CONFERENCE ON ALZHEIMER'S DRUG DISCOVERY

The annual Alzheimer's Drug Discovery Foundation (ADDF) conference brings together academic and industry scientists intent on accelerating the development of innovative treatments for Alzheimer’s di...

Companies [ 368 Associated Companies listed on BioPortfolio]

The Multiple Myeloma Research Foundation

Multiple myeloma is an incurable blood cancer. The five-year relative survival rate for multiple myeloma is approximately 34 percent, one of the lowest of all cancers. In 2009, ap...

Acorda Therapeutics

Acorda Therapeutics, Inc. was established in March 1995 to develop therapeutic products for spinal cord injury ("SCI") and other central nervous system disorders. Acorda is focusing its initial develo...

KineMed, Inc.

KineMed, Inc. ("KineMed" or the "Company") is a drug discovery and development company employing its proprietary translational medicine technology (AquaTag™ and KineMarkerâÂ...

ALung Technologies, Inc.

ALung Technologies, Inc. is commercializing artificial lung devices for the treatment of acute and chronic respiratory disorders. The company's Hemolung System, designed to replace or supplement the u...

Neovacs S.A.

Neovacs is a French biotechnology company focused on active immunotherapy for autoimmune and inflammatory diseases and cancer. Neovacs is a spin-off from Université Pierre et Marie Curie in P...

Diabetes Care Club

Diabetes Care Club, a Simplex brand, has grown to become the third largest mail-order supplier of diabetic testing supplies for seniors. The company provides home delivery...

IDS Ltd

From its establishment in 1977, simply as a Distributor of diagnostic products, IDS has become a globally-recognised innovator and marketeer in the IVD industry.The Company is particularly well-known...

National Disease Research Interchange (NDRI)

Promedior, Inc.

Promedior has developed a novel drug discovery platform to regulate the monocyte-derived cell populations that play key roles in fibrotic, inflammatory and autoimmune diseases. By...

Alvine Pharmaceuticals, Inc.

Alvine Pharmaceuticals, Inc. is a private, clinical-stage, specialty biopharmaceutical company located in San Carlos, CA, focused on the development of biologics targeting autoimm...

Clinical Trials [ 5223 Associated Clinical Trials listed on BioPortfolio]

Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants

To determine whether or not inhaled nitric oxide (iNO) safely decreases the incidence of chronic lung disease (CLD) in premature infants.

Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain

Noxious stimuli occurring intraoperatively and postoperatively generate central sensitization, decreasing pain thresholds and ultimately increasing analgesic requirements. The pathophysiol...

A Study for Monthly Methoxy Polyethylene Glycol-Epoetin Beta Treatment in Patients With Chronic Renal Anaemia

This open-label single-arm study will evaluate the efficacy, safety and tolerability of methoxy polyethylene glycol epoetin beta on long-term maintenance of haemoglobin levels in patients...

Calcineurin Inhibitor-free, Steroid-free Immunosuppressive Regimen in Simultaneous Islet-Kidney Transplantation for Uremic Type 1 Diabetic Patients

The investigators hypothesize that a calcineurin inhibitor-free, steroid-free, co-stimulatory blockade-based immunosuppressive regimen, in combination with a GLP-1 agonist, will reduce the...

Evaluating the Control of COPD Symptoms in Patients Treated With Tiotropium Bromide 18mcg Once Daily Alone, ADOAIR 50/250mcg Twice Daily Alone or ADOAIR 50/250mcg Plus Tiotropium Bromide 18mcg

The purpose of this study is to assess the control of COPD using a symptom and exacerbation risk based treatment strategy based on GOLD 2011. This study is conducted in Japanese subjects w...

A Phase 2a, Dose-Ranging Study to Evaluate the Safety, Pharmacokinetics and Efficacy of VX-135 With Ribavirin in Treatment-Naïve Subjects With Chronic Hepatitis C

The purpose of the study is to determine the safety, pharmacokinetics and efficacy of orally administered VX-135 with ribavirin in treatment naive subjects with chronic hepatitis C infecti...

A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)

The main purpose of the study is to evaluate the efficacy and safety of the study drug known as prasugrel for the reduction of Vaso-Occlusive Crisis events in pediatric participants with s...

Ventricular Arrhythmias in Uremic Cardiomyopathy

There is a certain gene called sarcoplasmic reticulum gene (SERCA2a), which is found in heart muscle. This gene is also found in blood vessels and skin tissue. When active this gene builds...

Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

This randomized phase II trial is studying how well giving tacrolimus and mycophenolate mofetil (MMF) together with or without sirolimus works in preventing acute graft-versus-host disease...

Erlotinib and Sirolimus for the Treatment of Metastatic Renal Cell Carcinoma

The purpose of this study is to test the safety and efficacy of the combination of erlotinib hydrochloride (Tarcevaâ„¢) and sirolimus (Rapamuneâ„¢) in the treatment of patients with metast...

Medical and Biotech [MESH] Definitions

Casuistry

A method of ETHICAL ANALYSIS that emphasizes practical problem solving through examining individual cases that are considered to be representative; sometimes used to denote specious argument or rationalization. Differentiate from casuistics, which is the recording and study of cases and disease.

Incidental Findings

Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.

Wasting Disease, Chronic

A transmissible spongiform encephalopathy (prion disease) of DEER and elk characterized by chronic weight loss leading to death. It is thought to spread by direct contact between animals or through environmental contamination with the prion protein (PRIONS).

Ulmus

A plant genus of the family ULMACEAE that is susceptible to Dutch elm disease which is caused by the ASCOMYCOTA fungus, Ophiostoma.

Receptor, Epha1

The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producing human hepatocellular carcinoma cell line and is highly conserved among many mammalian species. Overproduction of the EphA1 receptor is associated with tumors and tumor cells of epithelial origin. It is also expressed at high levels in LIVER; LUNG; and KIDNEY; which is in contrast to many other members of the Eph receptor that are found primarily in tissues of the nervous system.

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