Conduction defects - Biotech, Pharma and Life Science Channel

04:12 EDT 1st October 2014 | BioPortfolio

PubMed Articles [2338 Associated PubMed Articles listed on BioPortfolio]

Biotinidase deficiency and vascular ring malformation: case report.

Biotinidase deficiency is an autosomal recessive metabolic disorder that affects the cleavage of biotin. Family studies of the index case found that both parents are usually carriers and siblings have...

Evidence for an association between prematurity and enamel defects in permanent teeth is still relatively sparse.

Mixed-up results give misguided conclusions regarding enamel defects in permanent teeth in children born preterm.

The visual pathway-functional anatomy and pathology.

Visual failure of any kind is a common clinical presentation and indication for neuroimaging. Monocular deficits should concentrate the search to the anterior (prechiasmatic) visual pathway. Bitempora...

Long-term evaluation of a historical cohort of Iranian common variable immunodeficiency patients.

Objectives: Common variable immune deficiency (CVID) is the most frequent form of symptomatic primary immunodeficiency disease, characterized by hypogammaglobulinemia, recurrent infections and increas...

The immune escape in melanoma: role of the impaired dendritic cell function.

Melanoma is an immunogenic cancer that overcomes the control of the immune system through the production of tolerogenic cytokines and growth factors in the microenvironment. In melanoma, dendritic cel...

Neuropilin-1 enforces extracellular matrix signalling via ABL1 to promote angiogenesis.

Neuropilin-1 (NRP1), together with neuropilin-2, belongs to the neuropilin family. Neuropilins are transmembrane proteins essential for vascular and neural development and act as co-receptors for secr...

Guidelines for Diagnosis and Management of Beta-Thalassemia Intermedia.

Beta-thalassemia intermedia (β-TI) is a genetic variant of beta-thalassemias with a clinical disorder whose severity falls between thalassemia minor and thalassemia major. Different genetic defects a...

Functional Outcome after Reconstruction of Traumatic Soft Tissue Defects in the Lower Half of the Leg with Distally Based Medial Hemisoleus Muscle Flaps.

Modification of the Peroneal Perforator Flap for Treatment of Knee and Distal Femoral Defects.

News Articles [396 Associated News Articles listed on BioPortfolio]

In Light of a Recent Meta-Analysis of Paxil, The Law Office of Melinda J. Helbock A.P.C. Announces that it Continues to Investigate Potential Paxil Birth Defect Claims

A meta-analysis of published and unpublished clinical trial data, which was published in the journal PLOS ONE on Aug. 27, suggests GlaxoSmithKline overestimates the effectiveness of Paxil in the treat...

Pitt Researchers Search for Genetic Roots of Cleft Lip, Palate with Help from NIH Grant

An $11.8 million NIH grant will support research efforts to explore the genetic roots of cleft lip and cleft palate at the University of Pittsburgh School of Dental Medicine. Pittsburgh, Pennsylvania ...

Reata Announces the Initiation of Phase 2 Studies Examining RTA 408 for the Treatment of Friedreich's Ataxia and Mitochondrial Myopathies

IRVING, TX--(Marketwired - September 30, 2014) - Reata has received clearance from the Division of Neurology Products of the FDA to begin two new Phase 2 clinical programs in patients with Friedreich'...

Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features

Kristijan Ramadan and colleagues report the identification of three individuals from two families with biallelic inactivating mutations in SPRTN causing early onset hepatocellular carcinoma and defect...

New insights into how the heart forms may help identify heart defects

Cdc42 controls embryonic heart formation

Urban Air Initiative Launches Public Awareness Website

WICHITA, Kan., Sept. 29, 2014 /PRNewswire/ -- There's a new website drawing attention to the growing problem of toxic compounds in gasoline, with a call to action for the EPA to regulate some of the m...

How Genes Affect Facial Development

A zebrafish study shed light on how the structure of the face forms. Problems with equivalent genes in people can cause facial defects and other developmental issues.

New comic book explains to children about Primary Immunodeficiency

Primary Immunodeficiency (PID) refers to a group of disorders characterised by limited or absent function of the immune system. The majority of PIDs are inherited defects meaning that a component is e...

Study Identifies Unexpected Clue to Peripheral Neuropathies

CINCINNATI, Sept. 26, 2014 /PRNewswire-USNewswire/ -- New research shows that disrupting the molecular function of a tumor suppressor causes improper formation of a protective insulating sheath o...

NeuroMetrix Reports Publication of Study Demonstrating that DPNCheck is Effective at Detecting Diabetic Peripheral Neuropathy at all Stages of Severity

NeuroMetrix, Inc. (Nasdaq: NURO), today reported publication of results from a DPNCheck® study conducted at the Diabetes Research Unit of the Ipswich Hospital NHS Trust in the Un...

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Companies [12 Associated Companies listed on BioPortfolio]

Imbed Biosciences Inc.

Imbed Biosciences is a privately held medical device company, located in Madison, WI, that develops advanced materials for wound healing and surgical applications. It has develope...

Stratatech Corporation

Stratatech Corp. is a privately-held regenerative medicine company focused on the development and commercialization of cell-based, tissue-engineered skin substitute products for t...

Avita Medical Ltd.

Avita Medical (www.avitamedical.com) develops and distributes regenerative and tissue-engineered products for the treatment of a broad range of wounds, scars and skin defects. The...

NeuroMetrix

NeuroMetrix, Inc. was founded in June 1996 as a spin-off from the Harvard-M.I.T. Division of Health Sciences and Technology. The Company’s mission is to: Create value for our customers by developi...

NeuroMetrix, Inc.

NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...

AGA Medical Holdings, Inc.

AGA Medical, based in Plymouth, Minnesota, is a leading innovator and manufacturer of medical devices for the treatment of structural heart defects and vascular abnormalities. AGA...

Imbed Biosciences

Imbed Biosciences Inc. is a privately held medical device company located in Madison, WI. Company has patent-pending technologies on polymeric nanofilms and microfilms for deliver...

HeartGift Austin

HeartGift Austin provides life-saving surgery to repair congenital heart defects in children who live in countries where this kind of medical care is not available. We provide our...

Stratatech Corp.

Stratatech Corp. is a privately-held regenerative medicine company focused on the development and commercialization of cell-based, tissue-engineered skin substitute products for t...

Intra-Lock® International, Inc.

Intra-Lock® International Inc., headquartered in Boca Raton, Florida, USA, is a leading provider of innovative dental restoration solutions including a wide range of dental imp...

Clinical Trials [274 Associated Clinical Trials listed on BioPortfolio]

Clinical Investigation on the Blood Oxygenation at the Optic Nerve Head in Fabry Patients

This study aims to evaluate blood oxygenation at the optic nerve head in relation with visual field losses observed in many Fabry patients. Data collected will allow to evaluate if there ...

Are Corneal Epithelial Defects Related to Changes in Ocular Bacterial Flora in Patients With ANLDO

Comparison between patients with nasolacrimal duct obstruction and healthy patients and the influence of their bacterial flora on the corneal epithelium.

Dalfampridine for Imbalance in Multiple Sclerosis

Dalfampridine is a new medication that was FDA approved in 2010 to improve walking speed in people with Multiple Sclerosis (MS). People with MS walk slowly in part because MS damages the ...

Rehabilitation in Patients With Congenital Heart Disease

Exercise intolerance is a major burden for patients with complex congenital heart disease (CHD), significantly affecting their quality of life. Cardiopulmonary exercise testing provides a ...

Body Water Content in Cyanotic Congenital Heart Disease

Adults with cyanotic congenital heart disease have elevated levels of plasma proatrial natruretic peptide (proANP) which most likely results in chronic dehydration, leading to reduced oxyg...

A Double-Blind, Placebo-Controlled Trial To Evaluate Intravenous Gamma Globulin in Children With Symptomatic HIV Infection Receiving Zidovudine

To evaluate the clinical, immunologic, and virologic effects of oral zidovudine (AZT) plus intravenous immunoglobulin (IVIG) versus AZT plus placebo (albumin). It is estimated that by 1991...

Phase I/II Study of Recombinant Human Interferon-Gamma (rIFN-Gamma) in HIV-Infected Children

PRIMARY: To determine the safety and toxicity of recombinant interferon gamma-1b ( rIFN-gamma ) in HIV-infected children receiving ongoing zidovudine ( AZT ) or didanosine ( ddI ) therapy....

Copper Histidine Therapy for Menkes Diseases

Menkes Disease is a genetic disorder affecting the metabolism of copper. Patient with this disease are both physically and mentally retarded. Menkes disease is usually first detected in t...

Inflammatory Responses in Normal Volunteers and Patients With Abnormal Immune Responses

This study will investigate the inflammatory response. People with abnormal regulation of inflammation and immune defects often have an exaggerated or depressed inflammatory response that ...

Investigation of Heart Function in Patients With Heart Valve Defects

In this study researchers plan to perform a diagnostic test called transesophageal echocardiography in order to see and record the movement and function of the heart. Transesophageal echo...

Medical and Biotech [MESH] Definitions

Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.

Transmission of sound waves through vibration of bones in the SKULL to the inner ear (COCHLEA). By using bone conduction stimulation and by bypassing any OUTER EAR or MIDDLE EAR abnormalities, hearing thresholds of the cochlea can be determined. Bone conduction hearing differs from normal hearing which is based on air conduction stimulation via the EAR CANAL and the TYMPANIC MEMBRANE.

A drug used in the treatment of angina pectoris, heart failure, conduction defects, and myocardial infarction. It is a partial agonist at beta adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

An impulse-conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.

Impaired impulse conduction from HEART ATRIA to HEART VENTRICLES. AV block can mean delayed or completely blocked impulse conduction.

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