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Conduction defects - Biotech, Pharma and Life Science Channel

23:49 EDT 26th September 2016 | BioPortfolio

PubMed Articles [2242 Associated PubMed Articles listed on BioPortfolio]

The Role of Annealing Process in Ag-Based BaSnO3 Multilayer Thin Films.

The BaSnO3/Ag/BaSnO3 multilayer structure was designed and fabricated on a quartz glass by magnetron sputtering, followed by an annealing process at a temperature from 150 to 750 °C in air. In this ...

The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the breakdown of lignocellulose by Aspergillus niger.

Genes encoding the key transcription factors (TF) XlnR, ClrA and ClrB were deleted from Aspergillus niger and the resulting strains were assessed for growth on glucose and wheat straw, transcription o...

A reproducible protocol for neonatal ischemic injury and cardiac regeneration in neonatal mice.

Cardiac regeneration is one of the prime visions in cardiovascular research. The mouse neonatal apical resection and left anterior descending artery (LAD) ligation model introduced novel in vivo mamma...

Cloud point extraction and gas chromatography with direct microvial insert thermal desorption for the determination of haloanisoles in alcoholic beverages.

A sensitive analytical procedure for the determination of four haloanisoles (2,4,6 trichloroanisole, 2,4,6-tribromoanisole, 2,3,4,6-tetrachloroanisole and pentachloroanisole) related with cork taint d...

Port-to-port delivery: Mobilization of toxic sphingolipids via extracellular vesicles.

The discovery that most cells produce extracellular vesicles (EVs) and release them in the extracellular milieu has spurred the idea that these membranous cargoes spread pathogenic mechanisms. In the ...

New therapeutic approaches for Krabbe disease: The potential of pharmacological chaperones.

Missense mutations in the lysosomal hydrolase β-galactocerebrosidase (GALC) account for at least 40% of known cases of Krabbe disease (KD). Most of these missense mutations are predicted to disrupt t...

How membrane dysfunction influences neuronal survival pathways in sphingolipid storage disorders.

Sphingolipidoses are a class of inherited diseases that result from the toxic accumulation of undigested sphingolipids in lysosomes and other cellular membranes. Sphingolipids are particularly enriche...

Axonal pathology in Krabbe's disease: The cytoskeleton as an emerging therapeutic target.

In Krabbe's disease (KD), demyelination and myelin-independent axonal and neuronal defects contribute to the severe neuropathology. The toxic substrate that accumulates in this disease, psychosine, in...

Fluid levity of the cell: Role of membrane lipid architecture in genetic sphingolipidoses.

Sphingolipidoses arise from inherited loss of function of key enzymes regulating the sphingolipid (SL) metabolism and the accumulation of large quantities of these lipids in affected cells. Most frequ...

Clinical, electrophysiological, and biochemical markers of peripheral and central nervous system disease in canine globoid cell leukodystrophy (Krabbe's disease).

Globoid cell leukodystrophy (GLD), or Krabbe's disease, is a debilitating and always fatal pediatric neurodegenerative disease caused by a mutation in the gene encoding the hydrolytic enzyme galactosy...

News Articles [618 Associated News Articles listed on BioPortfolio]

TSHZ3 deletion causes an autism syndrome and defects in cortical projection neurons

Laurent Fasano and colleagues identify TSHZ3 deletions in patients with autism spectrum disorder. Tshz3-mutant mice show functional changes at synapses established by cortical projection neurons and e...

Regentis Receives IDE Approval for Pivotal GelrinC Clinical Trial

PRINCETON, New Jersey and OR AKIVA, Israel, September 26, 2016 /PRNewswire/ -- Regentis Biomaterials, a developer of hydrogels for tissue regeneration, announced it has received U.S. Food and Drug Ad...

Adult, larval insecticides pack deadly punch to mosquitoes, Zika -U.S.

Sept 23 (Reuters) - The unprecedented aerial spraying of products that kill both adult mosquitoes as well as their larvae delivered a "1-2 punch" that has stopped direct transmission of the Zika virus...

Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65

DNA-based vaccine guards against Zika in monkey study

An experimental DNA-based vaccine protected monkeys from infection with the birth defects-causing Zika virus, and it has proceeded to human safety trials, researchers report.

Swine flu vaccine is unlikely to raise risk of overall birth defects, study finds

Being given the H1N1 influenza vaccine during pregnancy does not seem to be associated with an increased risk of overall birth defects, a Swedish study published in Annals of Internal Medicine has... ...

Avita Medical to Hold ReCell(R) Symposium at Leading European Burns Association Course

NORTHRIDGE, CA and PERTH, AUSTRALIA and LONDON, UNITED KINGDOM -- (Marketwired) -- 09/22/16 -- Avita Medical Ltd (ASX: AVH) (OTCQX: AVMXY), a regenerative medicine company specializing in new treatme...

Defects at the spinterface disrupt transmission

Magnets made of organic materials have a number of advantages over the classic metal or alloy magnets. They are chemically more flexible, cheaper to make, and can be better adapted to various purposes...

Two mood drugs combat virus implicated in birth defects

Two mood-stabilizing drugs provide protection against a potentially dangerous virus implicated in birth defects as well as disease in people with compromised immune systems, Yale School of Medicine re...

Swine Flu Vaccine Safe in Early Pregnancy

Population-based study is the first to compare outcomes in exposed, unexposed siblings and finds no increased risk for birth defects associated with the H1N1 vaccine. Medscape Medical News

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Companies [14 Associated Companies listed on BioPortfolio]

St. Jude Medical and Mended Little Hearts

Mended Little Hearts plays a significant role in the lives of families with children diagnosed with CHDs. Through its support group meetings, health education to communities, advo...

The Sloan Firm

The Sloan Firm was established in 1980 and has offices in Longview and Houston, Texas. The Sloan Firm has an impressive track record in negotiations and litigation in its primary ...

Imbed Biosciences Inc.

Imbed Biosciences is a privately held medical device company, located in Madison, WI, that develops advanced materials for wound healing and surgical applications. It has develope...

Stratatech Corporation

Stratatech Corp. is a privately-held regenerative medicine company focused on the development and commercialization of cell-based, tissue-engineered skin substitute products for t...

Avita Medical Ltd.

Avita Medical (www.avitamedical.com) develops and distributes regenerative and tissue-engineered products for the treatment of a broad range of wounds, scars and skin defects. The...

NeuroMetrix

NeuroMetrix, Inc. was founded in June 1996 as a spin-off from the Harvard-M.I.T. Division of Health Sciences and Technology. The Company’s mission is to: Create value for our customers by developi...

NeuroMetrix, Inc.

NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...

AGA Medical Holdings, Inc.

AGA Medical, based in Plymouth, Minnesota, is a leading innovator and manufacturer of medical devices for the treatment of structural heart defects and vascular abnormalities. AGA...

Imbed Biosciences

Imbed Biosciences Inc. is a privately held medical device company located in Madison, WI. Company has patent-pending technologies on polymeric nanofilms and microfilms for deliver...

HeartGift Austin

HeartGift Austin provides life-saving surgery to repair congenital heart defects in children who live in countries where this kind of medical care is not available. We provide our...

Clinical Trials [473 Associated Clinical Trials listed on BioPortfolio]

The Cardiopulmonary Effect of Inhaled Beta-2-agonists on Adult Patients Born With Ventricular Septum Defects.

The overall objective for this study is to test whether β2-agonists will affect the cardiopulmonary capacity of VSD-operated patients compared with un-operated VSD-patients and healthy ag...

Infrared Thermography for Assessment of Caudal Block in Children

Regional analgesia via caudal neuraxial blockade provides pain relief for pediatric patients following urological and lower extremity procedures. The injection of local anesthetic into the...

Furcation Therapy With Enamel Matrix Derivative

Objective: To clinically evaluate mandibular furcation treated with Beta tricalcium phosphate/hydroxyapatite (βTCP/HA) isolated or combined with enamel matrix derivative (EMD + βTCP/HA) ...

Whole Exome Sequencing in Bicuspid Aortic Valve Patients

Bicuspid aortic valve (BAV), congenital anomaly present in 2% of the population, is defined by the presence of two sigmoid valves instead of three. It is conventionally associated with his...

Validation of a Production Method of Stem Cell Isolated From the Nasal Cavity for an Innovative Cell Therapy of Cleft Palate

Cell therapy appears to be an alternative to treat bone defects. Scientific advances have shown in animal models and in humans that mesenchymal stem cells were good candidates to support c...

Ability of a Molecule (Prima) to Restore Physiological Differentiation in Epithelium Expressing Gene p63

Ectodermal dysplasia associated with p63 is a rare disease which, in addition to limbic abnormalities, primarily affects the skin and cornea. The most common forms are called Ectrodactyly,...

Visual and Optics Impact of Refractive Surgery

Refractive surgery includes interventions to correct refractive errors, using a medical device such as a laser or an implant (intraocular lenses) or surgical instruments. The study disting...

Study of GLS-5700 in Dengue Virus Seropositive Adults

The clinical trial will assess the safety, tolerability, and immunogenicity of GLS-5700. GLS-5700 is a synthetic DNA plasmid vaccine against the Zika virus. This is a Phase 1 clinical tria...

Echocardiography-guided Transthoracic Radio Frequency/Laser Ablation for Ventricular Septum of Hypertrophic Obstructive Cardiomyopathy

Hypertrophic Obstructive Cardiomyopathy (HOCM) patients have significant clinical symptoms, including progressively increasing fatigue, angina, exertional dyspnea, and syncope. Conservativ...

National Register of Oesophageal Atresia

The esophageal atresia is a group of birth defects including a break in continuity of the esophagus with or without persistent communication with the trachea (tracheoesophageal fistula), s...

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Medical and Biotech [MESH] Definitions

Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.

Transmission of sound waves through vibration of bones in the SKULL to the inner ear (COCHLEA). By using bone conduction stimulation and by bypassing any OUTER EAR or MIDDLE EAR abnormalities, hearing thresholds of the cochlea can be determined. Bone conduction hearing differs from normal hearing which is based on air conduction stimulation via the EAR CANAL and the TYMPANIC MEMBRANE.

A drug used in the treatment of angina pectoris, heart failure, conduction defects, and myocardial infarction. It is a partial agonist at beta adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

An impulse-conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.

Impaired impulse conduction from HEART ATRIA to HEART VENTRICLES. AV block can mean delayed or completely blocked impulse conduction.

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