Conduction defects - Biotech, Pharma and Life Science Channel

07:57 EST 19th December 2014 | BioPortfolio

PubMed Articles [2373 Associated PubMed Articles listed on BioPortfolio]

The Bacterial Type III Secretion System as a Target for Developing New Antibiotics.

Antibiotic resistance in pathogens requires new targets for developing novel antibacterials. The bacterial type III secretion system (T3SS) is an attractive target for developing antibacterials as it ...

Head Muscle Development.

The developmental paths that lead to the formation of skeletal muscles in the head are distinct from those operating in the trunk. Craniofacial muscles are associated with head and neck structures. In...

Pre-eruptive Intracoronal Resorption of a Permanent First Molar.

For the last 70 years, the phenomenon of pre-eruptive intracoronal resorption (PIR) has been described in the literature, including a number of case reports illustrating the challenges clinicians face...

Developmental Defects of Enamel in Phenylketonuria Patients.

The purpose of this study was to determine the prevalence of developmental defects of enamel in patients diagnosed with phenylketonuria (PKU).

The man o' war mutation in UDP-xylose synthase favors the abortive catalytic cycle and uncovers a latent potential for hexamer formation.

The man 'o war (mow) phenotype in zebrafish is characterized by severe craniofacial defects due to a missense mutation in UDP-α-D-xylose synthase (UXS), an essential enzyme in proteoglycan biosynthes...

Reconstructing the Gauge Earlobe Defect.

The use of gauge earrings causes earlobe defects and, at times, significant contour distortion. Simple closure leads to inadequate results in most cases. We describe a stratified approach to assessing...

Syd/JIP3 and JNK Signaling Are Required for Myonuclear Positioning and Muscle Function.

Highlighting the importance of proper intracellular organization, many muscle diseases are characterized by mispositioned myonuclei. Proper positioning of myonuclei is dependent upon the microtubule m...

An Analysis of Common Indications for Bronchoscopy in Neonates and Findings Over a 10-Year Period.

There is a perceived increase in the number of microdirect laryngoscopies and bronchoscopies (MLBs) required on premature infants, infants with syndromic conditions, and those with complex congenital ...

Vangl2-Regulated Polarisation of Second Heart Field-Derived Cells Is Required for Outflow Tract Lengthening during Cardiac Development.

Planar cell polarity (PCP) is the mechanism by which cells orient themselves in the plane of an epithelium or during directed cell migration, and is regulated by a highly conserved signalling pathway....

Identification of Listeria monocytogenes Determinants Required for Biofilm Formation.

Listeria monocytogenes is a Gram-positive, food-borne pathogen of humans and animals. L. monocytogenes is considered to be a potential public health risk by the U.S. Food and Drug Administration (FDA)...

News Articles [378 Associated News Articles listed on BioPortfolio]

Statement Of Dr. Jennifer L. Howse, President, March Of Dimes On President Obama Signing The Newborn Screening Saves Lives Reauthorization Act Into Law

WASHINGTON, Dec. 18, 2014 /PRNewswire-USNewswire/ -- The March of Dimes released today the following statement from President Dr. Jennifer L. Howse as President Barack Obama signed into law H.R. ...

The March Of Dimes Greets The New Year With Six Simple Resolutions For A Healthy Pregnancy

WHITE PLAINS, N.Y., Dec. 18, 2014 /PRNewswire-USNewswire/ -- The March of Dimes is encouraging women who are pregnant, or planning to become pregnant, to make a New Year's resolution to be as healthy ...

The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells

The unfolded protein response (UPR) is a conserved stress-signaling pathway activated after accumulation of unfolded proteins within the endoplasmic reticulum (ER). Active UPR signaling leads to uncon...

Novel Tool to Study Life-Threatening Arrhythmias: A Genetically Engineered Pig

Researchers at NYU Langone Medical Center have developed the first large animal model of an inherited arrhythmic syndrome – an advance that will lead to a better understanding of the biologic mechan...

Hutchinson-Gilford Progeria syndrome: Substance from broccoli can moderate defects

Children who suffer from Hutchinson-Gilford Progeria syndrome age prematurely due to a defective protein in their cells. Scientists have now identified another important pathological factor: the syste...

Progeria research: Substance from broccoli can moderate defects

Children who suffer from Hutchinson-Gilford Progeria syndrome age prematurely due to a defective protein in their cells. Scientists at Technische Universität München have now identified another impo...

Substance from broccoli can moderate defects

(Technische Universitaet Muenchen) Children who suffer from Hutchinson-Gilford Progeria syndrome age prematurely due to a defective protein in their cells. Scientists at Technische Universität Münch...

A Novel Tool To Study Life-Threatening Arrhythmias: A Genetically Engineered Pig

NEW YORK, Dec. 15, 2014 /PRNewswire-USNewswire/ -- Researchers at NYU Langone Medical Center have developed the first large animal model of an inherited arrhythmic syndrome - an advance that will...

Cobalamin defects can explain neurologic regression in children

(HealthDay)—Cobalamin defects can account for neurologic regression in healthy children, according to a case report published online Dec. 15 in Pediatrics.

Gil Beyen Joins NOVADIP BIOSCIENCES Board of Directors

LOUVAIN-LA-NEUVE, Belgium, December 15, 2014 /PRNewswire/ -- NOVADIP BIOSCIENCES, an innovative biopharmaceutical company specializing in the discovery and development of new generation of regenerati...

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Companies [12 Associated Companies listed on BioPortfolio]

Imbed Biosciences Inc.

Imbed Biosciences is a privately held medical device company, located in Madison, WI, that develops advanced materials for wound healing and surgical applications. It has develope...

Stratatech Corporation

Stratatech Corp. is a privately-held regenerative medicine company focused on the development and commercialization of cell-based, tissue-engineered skin substitute products for t...

Avita Medical Ltd.

Avita Medical (www.avitamedical.com) develops and distributes regenerative and tissue-engineered products for the treatment of a broad range of wounds, scars and skin defects. The...

NeuroMetrix

NeuroMetrix, Inc. was founded in June 1996 as a spin-off from the Harvard-M.I.T. Division of Health Sciences and Technology. The Company’s mission is to: Create value for our customers by developi...

NeuroMetrix, Inc.

NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...

AGA Medical Holdings, Inc.

AGA Medical, based in Plymouth, Minnesota, is a leading innovator and manufacturer of medical devices for the treatment of structural heart defects and vascular abnormalities. AGA...

Imbed Biosciences

Imbed Biosciences Inc. is a privately held medical device company located in Madison, WI. Company has patent-pending technologies on polymeric nanofilms and microfilms for deliver...

HeartGift Austin

HeartGift Austin provides life-saving surgery to repair congenital heart defects in children who live in countries where this kind of medical care is not available. We provide our...

Stratatech Corp.

Stratatech Corp. is a privately-held regenerative medicine company focused on the development and commercialization of cell-based, tissue-engineered skin substitute products for t...

Intra-Lock® International, Inc.

Intra-Lock® International Inc., headquartered in Boca Raton, Florida, USA, is a leading provider of innovative dental restoration solutions including a wide range of dental imp...

Clinical Trials [283 Associated Clinical Trials listed on BioPortfolio]

PET Study of Non-Motor Symptoms of Parkinson Disease

This research plan is focused on neurochemical positron emission tomography (PET) studies of Parkinson disease (PD). PD is the most common neurodegenerative movement disorder, and consider...

PV Reconnection After PVAI at Different Power Settings and Adenosine Provocation

In this prospective randomized study, we aim to compare the rate of PV reconnection following PVAI performed at different energy settings (30 Watts vs 40 Watts) where dormant PV conduction...

Follow-up Study of Late Effects of Periconceptional Folic Acid in Mothers and Offspring in the Community Intervention Program Population: The Chinese Children and Families Study

Periconceptional folic acid supplements of 400 (Micro) daily prevent neural tube defects (NTD) in offspring. Some data suggest that periconceptional folic acid supplements, folate levels ...

Evaluation of Topical Citrullus Colocynthis Fruit Oil Efficacy in Treatment of Painful Peripheral Diabetic Neuropathy

This study is designed to evaluate the topical Citrullus colocynthis fruit oil efficacy in treatment of painful peripheral diabetic neuropathy (PDN) in a randomized double blind placebo-co...

Gene-activated Matrix for Bone Tissue Repair in Maxillofacial Surgery

The purpose of this study is to evaluate safety and efficacy of gene-activated matrix ("Nucleostim") for regeneration of bone tissue in maxillofacial area. Patients with congenital and acq...

UCB Antiepileptic Drugs (AED) Pregnancy Registry (Formerly the Keppra® Pregnancy Registry)

This is a prospective, observational, exposure-registration and follow-up study of women and their offspring exposed to Keppra® (levetiracetam) and Keppra XR® at the time of conception (...

RTA 408 Capsules in Patients With Mitochondrial Myopathy - MOTOR

Mitochondrial myopathies are a multisystemic group of disorders that are characterized by a wide range of biochemical and genetic mitochondrial defects and variable modes of inheritance. ...

Cardiac Resynchronization Therapy in Congenital Heart Defects

The objective of this multicentre prospective therapeutic study is to evaluate the effects of CRT on the right and left ventricular function of patients with CHD in the medium and long ter...

Safety and Effectiveness of the CustomFlex Artificial Iris Prosthesis for the Treatment of Iris Defects

The purpose of this study is to evaluate the safety and effectiveness of an artificial iris prosthesis for the treatment of iris defects.

Assessment of Autonomic Maturation in Neonatal Period and Early Neural Development From a Longitudinal Prospective Cohort

The heart rate variability assessment of the sympathetic-parasympathetic balance is a strong analytical tool in the autonomic nervous system (ANS) physiology, at each end of life. In neon...

Medical and Biotech [MESH] Definitions

Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.

Transmission of sound waves through vibration of bones in the SKULL to the inner ear (COCHLEA). By using bone conduction stimulation and by bypassing any OUTER EAR or MIDDLE EAR abnormalities, hearing thresholds of the cochlea can be determined. Bone conduction hearing differs from normal hearing which is based on air conduction stimulation via the EAR CANAL and the TYMPANIC MEMBRANE.

A drug used in the treatment of angina pectoris, heart failure, conduction defects, and myocardial infarction. It is a partial agonist at beta adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

An impulse-conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.

Impaired impulse conduction from HEART ATRIA to HEART VENTRICLES. AV block can mean delayed or completely blocked impulse conduction.

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