Conduction defects - Biotech, Pharma and Life Science Channel

06:39 EST 27th February 2015 | BioPortfolio

PubMed Articles [2296 Associated PubMed Articles listed on BioPortfolio]

Reengineering autologous bone grafts with the stem cell activator WNT3A.

Autologous bone grafting represents the standard of care for treating bone defects but this biomaterial is unreliable in older patients. The efficacy of an autograft can be traced back to multipotent ...

Pathway-driven discovery of epilepsy genes.

Epilepsy genes deliver critical insights into the molecular control of brain synchronization and are revolutionizing our understanding and treatment of the disease. The epilepsy-associated genome is r...

Extramacrochaetae functions in dorsal-ventral patterning of Drosophila imaginal discs.

One of the seminal events in the history of a tissue is the establishment of the anterior-posterior, dorsal-ventral (D/V) and proximal-distal axes. Axis formation is important for the regional specifi...

Splice-Correction Strategies for Treatment of X-Linked Agammaglobulinemia.

X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disease caused by mutations in the gene coding for Bruton's tyrosine kinase (BTK). Deficiency of BTK leads to a developmental block in B...

Implanted Scaffold-Free Prevascularized Constructs Promote Tissue Repair.

To evaluate the anastomotic potential of prevascular tissue constructs generated from scaffold-free self-assembly of human endothelial and fibroblast cells, tissue constructs were implanted into athym...

Congenital Malformations and Consequential Epidemiology.

A call for a shift in the discipline of epidemiology, away from those aimed at identifying risk factors and toward those aimed at more directly improving health - so called consequential epidemiology....

A Novel Mutation in Motor Domain of KIF5A Associated With an HSP/Axonal Neuropathy Phenotype.

SPG10 is an autosomal dominant hereditary spastic paraplegia (HSP) caused by mutations in the gene KIF5A encoding the heavy chain of kinesin, a motor protein implied in motility functions within cells...

Practical rules for electrodiagnosis in suspected multifocal motor neuropathy.

Multifocal motor neuropathy (MMN) with conduction block (CB) is a rare chronic immune-mediated neuropathy, but important to diagnose as it is treatable. The key features in prototypic MMN are electrod...

Photothermal synthesis of ultrafine CuxO nanoparticles on carbon nanotubes for photosensitized degradation.

We exploit a facile strategy for photothermal synthesis (PTS) of CuxO nanoparticles (NPs) on carbon nanotubes (CNTs) suspended in solution, where the pulsed laser can penetrate through the liquid unim...

PARK2/Parkin becomes critical when DNM1L/Drp1 is absent.

Maintaining mitochondrial dynamics and proper execution of mitophagy is crucial for sustaining cellular health. Defects in these processes have been linked to cardiovascular diseases and neurodegenera...

News Articles [350 Associated News Articles listed on BioPortfolio]

The Children's Hospital of Philadelphia Supports Public Reporting of Pediatric and Congenital Heart Surgery Outcomes

PHILADELPHIA, Feb. 26, 2015 /PRNewswire-USNewswire/ -- The Children's Hospital of Philadelphia supports the accomplishments of the Pennsylvania Health Care Cost Containment Council (PHC4), which ...

Zofran Lawsuit Website Launches for Birth Defect Allegations

National pharmaceutical and medical device law firm, the Onder Law Firm, provides comprehensive fetal risk information and no-cost, confidential case review to families whose baby was born with a birt...

Human Papillomavirus Infections Therapeutics Market Clinical Trials H2 2014 Review Research Report

DALLAS, February 25, 2015 /PRNewswire/ -- ReportsnReports.com adds "Human Papillomavirus Infections Global Clinical Trials Review, H2, 2014" to its store. This report provides data on clinical trial ...

Bernstein Liebhard LLP Launches Zofran Lawsuit Website in Response to Recent Litigation Involving Anti-Nausea Medication

NEW YORK, Feb. 24, 2015 /PRNewswire/ -- The nationwide law firm of Bernstein Liebhard LLP announces the launch of a new Zofran lawsuit (http://www.zofranlawsuit2015.com/ ) website to keep the public i...

Amelotin molecule plays a critical role in tooth enamel maturation

(International & American Associations for Dental Research) Today, the International and American Associations for Dental Research published an innovative developmental biology study by lead researche...

Epigenome orchestrates embryonic development

(Washington University School of Medicine) Studying zebrafish embryos, researchers at Washington University School of Medicine in St. Louis have shown that the epigenome plays a significant part in gu...

New insight into fragile protein linked to cancer, autism

In recent years, scientists have found a surprising a connection between some people with autism and certain cancer patients: They have mutations in the same gene, one that codes for a protein critica...

New Clues to Cause of Birth Defects in Children from Older Mothers

(Science Daily) – Researchers at Albert Einstein College of Medicine of Yeshiva University have found a possible clue to why older mothers face a higher risk for having babies born with conditio...

Folic acid fortification to prevent birth defects hits FDA roadblock

Preventing certain devastating birth defects has become as easy as pie crust - and bread, cereal, pasta, and other grain products.

New clues to causes of birth defects in children from older mothers

A possible clue has been found to why older mothers face a higher risk for having babies born with conditions such as Down syndrome that are characterized by abnormal chromosome numbers.

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Companies [13 Associated Companies listed on BioPortfolio]

The Sloan Firm

The Sloan Firm was established in 1980 and has offices in Longview and Houston, Texas. The Sloan Firm has an impressive track record in negotiations and litigation in its primary ...

Imbed Biosciences Inc.

Imbed Biosciences is a privately held medical device company, located in Madison, WI, that develops advanced materials for wound healing and surgical applications. It has develope...

Stratatech Corporation

Stratatech Corp. is a privately-held regenerative medicine company focused on the development and commercialization of cell-based, tissue-engineered skin substitute products for t...

Avita Medical Ltd.

Avita Medical (www.avitamedical.com) develops and distributes regenerative and tissue-engineered products for the treatment of a broad range of wounds, scars and skin defects. The...

NeuroMetrix

NeuroMetrix, Inc. was founded in June 1996 as a spin-off from the Harvard-M.I.T. Division of Health Sciences and Technology. The Company’s mission is to: Create value for our customers by developi...

NeuroMetrix, Inc.

NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...

AGA Medical Holdings, Inc.

AGA Medical, based in Plymouth, Minnesota, is a leading innovator and manufacturer of medical devices for the treatment of structural heart defects and vascular abnormalities. AGA...

Imbed Biosciences

Imbed Biosciences Inc. is a privately held medical device company located in Madison, WI. Company has patent-pending technologies on polymeric nanofilms and microfilms for deliver...

HeartGift Austin

HeartGift Austin provides life-saving surgery to repair congenital heart defects in children who live in countries where this kind of medical care is not available. We provide our...

Stratatech Corp.

Stratatech Corp. is a privately-held regenerative medicine company focused on the development and commercialization of cell-based, tissue-engineered skin substitute products for t...

Clinical Trials [288 Associated Clinical Trials listed on BioPortfolio]

IVIg for Demyelination in Diabetes Mellitus

The purpose of this study is to determine whether intravenous immunoglobulin (IVIg) is an effective intervention for patients with diabetes, peripheral neuropathy, and demyelination on ner...

Triple-site Biventricular Stimulation in the Optimization of CRT

Cardiac resynchronization is a recommended therapy for patients with advanced heart failure, under optimized medical treatment with reduced left ventricular ejection fraction and prolonged...

Ultrasonographic Assessment of Carpal Tunnel Syndrome

Mucopolysaccharidosis are lysosomal storage disorders such as Hunter, Hurler, and Sanfilippo syndromes. These patients have a genetic enzyme deficiency that results in the inability to de...

Regeneration of Human Intrabony Defects With rhFGF-2/HA

BACKGROUND: Periodontal disease is an infection that results in progressive loss of dental support, which may lead to tooth loss.. The goal of the present study was to evaluate if recombin...

Safety Study of Spray-Dried Solvent/Detergent-Treated Plasma for Infusion in Healthy Volunteers

This study is a Phase 1, single-center, open-label, ascending dose study which will assess the safety and tolerability of 5 doses of spray-dried solvent/detergent treated plasma (Resusix®...

Safety and Efficacy Study of Autologous Bone Marrow Aspirate Concentrate for No-Option Critical Limb Ischemia

The aim of the presented clinical trial is to evaluate a hypothesis, that BMAC prepared from bone marrow aspirate and injected intramuscularly into ischemic areas of the lower extremity in...

PET Study of Non-Motor Symptoms of Parkinson Disease

This research plan is focused on neurochemical positron emission tomography (PET) studies of Parkinson disease (PD). PD is the most common neurodegenerative movement disorder, and consider...

PV Reconnection After PVAI at Different Power Settings and Adenosine Provocation

In this prospective randomized study, we aim to compare the rate of PV reconnection following PVAI performed at different energy settings (30 Watts vs 40 Watts) where dormant PV conduction...

Follow-up Study of Late Effects of Periconceptional Folic Acid in Mothers and Offspring in the Community Intervention Program Population: The Chinese Children and Families Study

Periconceptional folic acid supplements of 400 (Micro) daily prevent neural tube defects (NTD) in offspring. Some data suggest that periconceptional folic acid supplements, folate levels ...

Evaluation of Topical Citrullus Colocynthis Fruit Oil Efficacy in Treatment of Painful Peripheral Diabetic Neuropathy

This study is designed to evaluate the topical Citrullus colocynthis fruit oil efficacy in treatment of painful peripheral diabetic neuropathy (PDN) in a randomized double blind placebo-co...

Medical and Biotech [MESH] Definitions

Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.

Transmission of sound waves through vibration of bones in the SKULL to the inner ear (COCHLEA). By using bone conduction stimulation and by bypassing any OUTER EAR or MIDDLE EAR abnormalities, hearing thresholds of the cochlea can be determined. Bone conduction hearing differs from normal hearing which is based on air conduction stimulation via the EAR CANAL and the TYMPANIC MEMBRANE.

A drug used in the treatment of angina pectoris, heart failure, conduction defects, and myocardial infarction. It is a partial agonist at beta adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

An impulse-conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.

Impaired impulse conduction from HEART ATRIA to HEART VENTRICLES. AV block can mean delayed or completely blocked impulse conduction.

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