Conduction defects - Biotech, Pharma and Life Science Channel

14:08 EST 21st November 2014 | BioPortfolio

PubMed Articles [2370 Associated PubMed Articles listed on BioPortfolio]

Head Muscle Development.

The developmental paths that lead to the formation of skeletal muscles in the head are distinct from those operating in the trunk. Craniofacial muscles are associated with head and neck structures. In...

Folate, vitamin B12, and vitamin B6 status of a group of high socioeconomic status women in the Alberta Pregnancy Outcomes and Nutrition (APrON) cohort.

Folic acid supplementation and food fortification policies have improved folate status in North American women of child bearing age. Recent studies have reported the possible inadequacy of vitamin B12...

Transport and thermoelectric properties of polyaniline/reduced graphene oxide nanocomposites.

Polyanilines (PANI)/reduced graphene oxide (RGO) nanocomposites are chemically synthesized. Their structure and morphology are characterized by scanning and transmission electron microscopies, x-ray d...

Electronic and Structural Differences between Wurtzite and Zinc Blende InAs Nanowire Surfaces: Experiment and Theory.

We determine the detailed differences in geometry and band structure between wurtzite (Wz) and zinc blende (Zb) InAs nanowire (NW) surfaces using scanning tunneling microscopy/spectroscopy and photoem...

Late-Onset of Spinal Neurodegeneration in Knock-In Mice Expressing a Mutant BiP.

Most human neurodegenerative diseases are sporadic, and appear later in life. While the underlying mechanisms of the progression of those diseases are still unclear, investigations into the familial f...

High-resolution Enabled 12-Plex DiLeu Isobaric Tags for Quantitative Proteomics.

Multiplex isobaric tags (TMT, iTRAQ) are a valuable tool for high-throughput mass spectrometry-based quantitative proteomics. We have developed our own multiplex isobaric tags, DiLeu, that feature qua...

Identification and Functional Analysis of a SLC33A1: c.339T>G (p.Ser113Arg) Variant in the Original SPG42 Family.

Using whole exome sequencing, we surveyed all the potential pathogenic variants in an SPG42 family and found five SNPs and four indels that are shared by two patients and lie in the mapped region. Two...

FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry.

Deficiencies in fragile X mental retardation protein (FMRP) are the most common cause of inherited intellectual disability, fragile X syndrome (FXS), with symptoms manifesting during infancy and early...

Identification and in vivo functional characterization of novel compound heterozygous BMP1 variants in osteogenesis imperfecta.

Osteogenesis imperfecta (OI) comprises a heterogeneous group of disorders that are characterized by susceptibility to bone fractures, and range in severity from a subtle increase in fracture frequency...

Effects of Doping on Transport Properties in Cu-Bi-Se-Based Thermoelectric Materials.

The thermoelectric properties of Zn-, In-, and I-doped Cu1.7Bi4.7Se8 pavonite homologues were investigated in the temperature range from 300 to 560 K. On the basis of the comprehensive structural anal...

News Articles [369 Associated News Articles listed on BioPortfolio]

Arizona sues General Motors over delayed safety recalls, seeks potentially billions in fines

Arizona's attorney general is suing General Motors and seeking potentially billions of dollars in fines against the auto giant for failing to recall millions of cars and trucks that had safety defects...

3-D Model of Heart May Help Surgeons Fix Defects

WEDNESDAY, Nov. 19, 2014 -- Being able to examine a 3-D model of the heart may boost surgeons' ability to treat patients born with complex cardiac defects, a new study suggests. Heart surgeons typical...

Targeted gene disruption by use of transcription activator-like effector nuclease (TALEN) in the water flea Daphnia pulex

Background: The cosmopolitan microcrustacean Daphnia pulex provides a model system for both human health research and monitoring ecosystem integrity. It is the first crustacean to have its complete ge...

The small GTPase Arf1 modulates mitochondrial morphology and function

The small GTPase Arf1 plays critical roles in membrane traffic by initiating the recruitment of coat proteins and by modulating the activity of lipid-modifying enzymes. Here, we report an unexpected b...

SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs

Although splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis. The molecular cause of this defect is unknown. Here, we...

Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1

Faithful chromosome segregation during mitosis is tightly regulated by opposing activities of Aurora B kinase and protein phosphatase-1 (PP1). PP1 function at kinetochores has been linked to SDS22, bu...

Splicing together sister chromatids

Splicing of pre-mRNAs is a necessary step for expression of the majority of genes in higher eukaryotes, and its regulation through alternative splice site selection shapes their proteomes. Defects in ...

Remotely controlled magnetic nanoparticles stimulate stem cells to regenerate bones

Researchers in bone tissue regeneration believe they have made a significant breakthrough for sufferers of bone trauma, disease or defects such as osteoporosis.

Pulse oximetry screenings save lives of babies with congenital heart defects

Screening for congenital heart defects with pulse oximetry identified newborn babies with previously unsuspected critical congenital heart defects (CCHD), according to research presented at the Americ...

BestMassage.com Deeply Discounts More Popular Massage Tables and Massage Chairs

BestMassage.com, the international massage table and supplies warehouse, has added newly reduced popular massage tables and chairs to its Discount Massage Table Category Chicago, IL (PRWEB) November 1...

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Companies [12 Associated Companies listed on BioPortfolio]

Imbed Biosciences Inc.

Imbed Biosciences is a privately held medical device company, located in Madison, WI, that develops advanced materials for wound healing and surgical applications. It has develope...

Stratatech Corporation

Stratatech Corp. is a privately-held regenerative medicine company focused on the development and commercialization of cell-based, tissue-engineered skin substitute products for t...

Avita Medical Ltd.

Avita Medical (www.avitamedical.com) develops and distributes regenerative and tissue-engineered products for the treatment of a broad range of wounds, scars and skin defects. The...

NeuroMetrix

NeuroMetrix, Inc. was founded in June 1996 as a spin-off from the Harvard-M.I.T. Division of Health Sciences and Technology. The Company’s mission is to: Create value for our customers by developi...

NeuroMetrix, Inc.

NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...

AGA Medical Holdings, Inc.

AGA Medical, based in Plymouth, Minnesota, is a leading innovator and manufacturer of medical devices for the treatment of structural heart defects and vascular abnormalities. AGA...

Imbed Biosciences

Imbed Biosciences Inc. is a privately held medical device company located in Madison, WI. Company has patent-pending technologies on polymeric nanofilms and microfilms for deliver...

HeartGift Austin

HeartGift Austin provides life-saving surgery to repair congenital heart defects in children who live in countries where this kind of medical care is not available. We provide our...

Stratatech Corp.

Stratatech Corp. is a privately-held regenerative medicine company focused on the development and commercialization of cell-based, tissue-engineered skin substitute products for t...

Intra-Lock® International, Inc.

Intra-Lock® International Inc., headquartered in Boca Raton, Florida, USA, is a leading provider of innovative dental restoration solutions including a wide range of dental imp...

Clinical Trials [279 Associated Clinical Trials listed on BioPortfolio]

Gene-activated Matrix for Bone Tissue Repair in Maxillofacial Surgery

The purpose of this study is to evaluate safety and efficacy of gene-activated matrix ("Nucleostim") for regeneration of bone tissue in maxillofacial area. Patients with congenital and acq...

UCB Antiepileptic Drugs (AED) Pregnancy Registry (Formerly the Keppra® Pregnancy Registry)

This is a prospective, observational, exposure-registration and follow-up study of women and their offspring exposed to Keppra® (levetiracetam) and Keppra XR® at the time of conception (...

RTA 408 Capsules in Patients With Mitochondrial Myopathy - MOTOR

Mitochondrial myopathies are a multisystemic group of disorders that are characterized by a wide range of biochemical and genetic mitochondrial defects and variable modes of inheritance. ...

Cardiac Resynchronization Therapy in Congenital Heart Defects

The objective of this multicentre prospective therapeutic study is to evaluate the effects of CRT on the right and left ventricular function of patients with CHD in the medium and long ter...

Safety and Effectiveness of the CustomFlex Artificial Iris Prosthesis for the Treatment of Iris Defects

The purpose of this study is to evaluate the safety and effectiveness of an artificial iris prosthesis for the treatment of iris defects.

Assessment of Autonomic Maturation in Neonatal Period and Early Neural Development From a Longitudinal Prospective Cohort

The heart rate variability assessment of the sympathetic-parasympathetic balance is a strong analytical tool in the autonomic nervous system (ANS) physiology, at each end of life. In neon...

Clinical Investigation on the Blood Oxygenation at the Optic Nerve Head in Fabry Patients

This study aims to evaluate blood oxygenation at the optic nerve head in relation with visual field losses observed in many Fabry patients. Data collected will allow to evaluate if there ...

Are Corneal Epithelial Defects Related to Changes in Ocular Bacterial Flora in Patients With ANLDO

Comparison between patients with nasolacrimal duct obstruction and healthy patients and the influence of their bacterial flora on the corneal epithelium.

Dalfampridine for Imbalance in Multiple Sclerosis

Dalfampridine is a new medication that was FDA approved in 2010 to improve walking speed in people with Multiple Sclerosis (MS). People with MS walk slowly in part because MS damages the ...

Rehabilitation in Patients With Congenital Heart Disease

Exercise intolerance is a major burden for patients with complex congenital heart disease (CHD), significantly affecting their quality of life. Cardiopulmonary exercise testing provides a ...

Medical and Biotech [MESH] Definitions

Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.

Transmission of sound waves through vibration of bones in the SKULL to the inner ear (COCHLEA). By using bone conduction stimulation and by bypassing any OUTER EAR or MIDDLE EAR abnormalities, hearing thresholds of the cochlea can be determined. Bone conduction hearing differs from normal hearing which is based on air conduction stimulation via the EAR CANAL and the TYMPANIC MEMBRANE.

A drug used in the treatment of angina pectoris, heart failure, conduction defects, and myocardial infarction. It is a partial agonist at beta adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

An impulse-conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.

Impaired impulse conduction from HEART ATRIA to HEART VENTRICLES. AV block can mean delayed or completely blocked impulse conduction.

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