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Conduction defects - Biotech, Pharma and Life Science Channel

16:15 EDT 28th July 2016 | BioPortfolio

PubMed Articles [2195 Associated PubMed Articles listed on BioPortfolio]

The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the breakdown of lignocellulose by Aspergillus niger.

Genes encoding the key transcription factors (TF) XlnR, ClrA and ClrB were deleted from Aspergillus niger and the resulting strains were assessed for growth on glucose and wheat straw, transcription o...

Hypertrophic pachymeningitis.

Hypertrophic Pachymeningitis (HP) denotes inflammation and thickening of the dura mater that can be idiopathic or secondary to a wide variety of conditions. Clinically, HP can present as debilitating ...

Genetic insights into migraine and glutamate: a protagonist driving the headache.

Migraine is a complex polygenic disorder that continues to be a great source of morbidity in the developed world with a prevalence of 12% in the Caucasian population. Genetic and pharmacological studi...

217 YAP Is Ready to Rac and Rho: Elucidation of a Novel YAP-Driven Network That Potentiates Brain Cancer Cell Dispersal and Confers Poor Survival in Patients.

Molecular pathways linking cell polarization and migration to extracellular cues regulate many pathological processes, including progression of aggressive and infiltrative cancers. Glioblastoma (GBM),...

8. Low-Intensity Pulsed Ultrasound (LIPUS) Treatment for the Patient With Bone Reconstruction by the Masquelet Technique Using RIA.

The Masquelet technique is a relatively new option in the management of bone defects. It consists of 2-stage surgery. At first surgery, a cement spacer is placed to fill the bone defect. After a waiti...

Von Willebrand Factor Multimers during Transcatheter Aortic-Valve Replacement.

Background Postprocedural aortic regurgitation occurs in 10 to 20% of patients undergoing transcatheter aortic-valve replacement (TAVR) for aortic stenosis. We hypothesized that assessment of defects ...

Inherited platelet dysfunction and hematopoietic transcription factor mutations.

Transcription factors (TFs) are proteins that bind to specific DNA sequences and regulate expression of genes. The molecular and genetic mechanisms in most patients with inherited platelet dysfunction...

Fabrication & Characterization of ZnO Langmuir-Blodgett films and its use in Metal-Insulator-Metal Tunnel Diode.

Metal-insulator-metal tunnel diodes have great potential for use in infrared detection and energy harvesting applications. The quantum based tunneling mechanism of electrons in MIM (Metal-Insulator-Me...

Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.

The RV254 cohort of HIV-infected very early acute (4thG stage 1 and 2) (stage 1/2) and late acute (4thG stage 3) (stage 3) individuals was used to study T helper- B cell responses in acute HIV infecti...

Autophagy in Saccharomyces cerevisiae requires the monomeric GTP-binding proteins, Arl1 and Ypt6.

Macroautophagy/autophagy is a cellular degradation process that sequesters organelles or proteins into a double-membrane structure called the phagophore; this transient compartment matures into an aut...

News Articles [728 Associated News Articles listed on BioPortfolio]

Strong early data on haemophilia gene therapy boosts Biomarin

Biomarin has presented interim results from a Phase I/II study that is being hailed as positive “proof-of-concept” data for their BMN 270 gene therapy in haemophilia A. In the trial, nine patients...

Miami blood donations halted over Zika fears

US regulators Thursday called for a halt to blood donations in the Miami area as investigators probe four potential non-travel associated cases of the mosquito-borne Zika virus, which can cause birth ...

New genetic syndrome tied to defects in protein transport

An international team of researchers has discovered the mutation responsible for a rare, newly identified genetic disorder that causes craniofacial abnormalities and developmental delays. The mutation...

Some Kids With Severe Birth Defects Living Longer (CME/CE)

(MedPage Today) -- Children with trisomy 13 and 18 survived for a decade in a Canadian study

Brazil asks whether Zika acts alone to cause birth defects

Puzzling distribution of cases suggests Zika is not the only factor in reported microcephaly surge.

Rhythm Announces "The Genetic Obesity Project" to Expand Understanding of Rare Genetic Disorders of Obesity

BOSTON, July 27, 2016 /PRNewswire/ -- Rhythm today announced "The Genetic Obesity Project" to improve the medical and scientific understanding of severe life-threatening obesity that is caused by...

Better understanding of glucosamine action may help to avoid birth defects in diabetic pregnancies 

Most pregnant women with well-controlled diabetes give birth to healthy children. But their babies run much higher risks of birth defects than babies born to women without diabetes, because very early...

Severe birth defects are not as lethal as docs once said

Trisomy 13 and trisomy 18 were once thought to be death sentences. But a new study suggests they're not always as lethal as doctors have advised parents.

Study: Severe Birth Defects Not as Lethal as Docs Once Said

Parents of newborns with rare genetic conditions used to hear the grim words that the severe birth defects were "incompatible with life." Support groups and social medi

Severe birth defects not as lethal as docs once said: study

Parents of newborns with rare genetic conditions used to hear the grim words that the severe birth defects were "incompatible with life." Support groups and social media showing the exceptions have ch...

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Companies [14 Associated Companies listed on BioPortfolio]

St. Jude Medical and Mended Little Hearts

Mended Little Hearts plays a significant role in the lives of families with children diagnosed with CHDs. Through its support group meetings, health education to communities, advo...

The Sloan Firm

The Sloan Firm was established in 1980 and has offices in Longview and Houston, Texas. The Sloan Firm has an impressive track record in negotiations and litigation in its primary ...

Imbed Biosciences Inc.

Imbed Biosciences is a privately held medical device company, located in Madison, WI, that develops advanced materials for wound healing and surgical applications. It has develope...

Stratatech Corporation

Stratatech Corp. is a privately-held regenerative medicine company focused on the development and commercialization of cell-based, tissue-engineered skin substitute products for t...

Avita Medical Ltd.

Avita Medical (www.avitamedical.com) develops and distributes regenerative and tissue-engineered products for the treatment of a broad range of wounds, scars and skin defects. The...

NeuroMetrix

NeuroMetrix, Inc. was founded in June 1996 as a spin-off from the Harvard-M.I.T. Division of Health Sciences and Technology. The Company’s mission is to: Create value for our customers by developi...

NeuroMetrix, Inc.

NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...

AGA Medical Holdings, Inc.

AGA Medical, based in Plymouth, Minnesota, is a leading innovator and manufacturer of medical devices for the treatment of structural heart defects and vascular abnormalities. AGA...

Imbed Biosciences

Imbed Biosciences Inc. is a privately held medical device company located in Madison, WI. Company has patent-pending technologies on polymeric nanofilms and microfilms for deliver...

HeartGift Austin

HeartGift Austin provides life-saving surgery to repair congenital heart defects in children who live in countries where this kind of medical care is not available. We provide our...

Clinical Trials [453 Associated Clinical Trials listed on BioPortfolio]

Filling Bone Defects/Voids With Autologous BonoFill-II for Maxillofacial Bone Regeneration

The purpose of this clinical study is to evaluate the safety and the efficacy of BonoFill-II as a bone filler containing the patient's own (autologous) adipose (fat) tissue-derived cells i...

Genetic Determinism of Epithelial Barrier Defects in Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) profoundly affects the quality of life. Mucosal micro-inflammation, epithelial permeability disorder and proteases activity increase have been demonstrated i...

What Benefit of a Full Analysis of Exome? Routine Care Study in Patients With Solid Tumors

The management of cancers and their therapeutic guidance was until shortly mostly based on histopathological considerations of the tumor. the development of targeted therapies is a turning...

NuTech Affinity™ for the Treatment of Chondral Defects

This study was designed to evaluate the long term effectiveness of a product used in knee surgery called Affinity™ Membrane.

Application of 30 Kilohertz Currents in Whiplash

The purpose of this study is to determine whether the transcutaneous application of unmodulated 30 Kilohertz (KHz) alternating currents could produce a quickly conduction block and if the ...

Coronally Advanced Flap and Prf With or Without Demineralized Freeze-dried Bone Allograft in Gingival Recession

- Gingival recession is defined as the apical migration of gingival margin beyond cemento-enamel junction with the exposure of root surface. More than 20% of the population pres...

The Fontan Education Study: A Randomized Control Trial

The Fontan Education Study is a cluster randomized controlled trial evaluating the impact of a novel education program in combination with usual care, versus usual care alone, on preparing...

Studying Finger-thumb Grip in Patients With Carpal Tunnel Syndrome

INTRODUCTION Carpal tunnel syndrome (CTS) is a common condition that results in impaired hand function. In cases of CTS the "pinch grip" force between the thumb and index finger becomes un...

Regenerative Combined Therapy With Enamel Matrix Derivative and Biphasic Calcium Phosphate Graft

Background: The use of Enamel Matrix Derivative (EMD) when dealing with non-contained defects may be limited, as EMD does not maintain a space itself. It has been proposed the use of combi...

Computer Based Algorithm for Patient Specific Implants for Cranioplasty in Patients With Skull Defects

Patients with skull defects after craniotomy for example tumor resection, head trauma, stroke, need a reimplantation of the bone afterwards. For some circumstances, their own bone cannot b...

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Medical and Biotech [MESH] Definitions

Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.

Transmission of sound waves through vibration of bones in the SKULL to the inner ear (COCHLEA). By using bone conduction stimulation and by bypassing any OUTER EAR or MIDDLE EAR abnormalities, hearing thresholds of the cochlea can be determined. Bone conduction hearing differs from normal hearing which is based on air conduction stimulation via the EAR CANAL and the TYMPANIC MEMBRANE.

A drug used in the treatment of angina pectoris, heart failure, conduction defects, and myocardial infarction. It is a partial agonist at beta adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

An impulse-conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.

Impaired impulse conduction from HEART ATRIA to HEART VENTRICLES. AV block can mean delayed or completely blocked impulse conduction.

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