Corneal Limbal Stem Cell Transplantation - Biotech, Pharma and Life Science Channel
PubMed Articles
Despite the well-defined role of autologous haematopoietic stem cell transplantation (autoHCT) in the treatment of patients with relapsed or refractory Hodgkin lymphoma (HL), relapse remains the main...
The heart contains various types of cells, including cardiomyocytes, cardiac fibroblasts, many kinds of immune cells and vascular cells. Initial studies mainly focused on cardiomyocytes, which directl...
In vitro and in vivo investigations of a modified textile keratoprosthesis : ACTO TexKPRO.
BACKGROUND: Clinical application of a keratoprosthesis (KPRO) is still a challenging task. Recent developments reflect the concepts of nut and bolt, intrastromal implantation or an osteoodontokeratopr...
Prophylaxis and management of complications in penetrating keratoplasty.
Besides routine postoperative follow-up the prophylaxis of complications in penetrating keratoplasty (PKP) includes special preoperative and intraoperative aspects. Preoperative prophylaxis consists o...
It is well accepted that Ag-induced B cell differentiation often results in the generation of exceptionally long-lived plasma cells. Much of the work supporting this viewpoint stems from studies focus...
Research highlights and editors' picks.
Are nonesterified Fatty acids protective in chronic allograft nephropathy?
Do cryopreserved regulatory T cells retain their suppressive potency?
Insulin resistance (IR) and pancreatic β-cell dysfunction lead to type 2 diabetes mellitus (DM). We tested whether risk factors would differ for DM that was preceded predominantly by IR, β-cell dysf...
News Articles
Exposing tissue to low levels of BPA linked to greater incidence of prostate cancer
Exposing developing tissue to low levels of the plastic bisphenol A, commonly known as BPA, is linked to a greater incidence of prostate cancer in tissue grown from human prostate stem cells, a new st...
Researchers identify biochemical pathway essential for promoting head and neck cancer
A study led by researchers at The Ohio State University Comprehensive Cancer Center-- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has identified a biochemical pathway in c...
Increased Risk Of Prostate Cancer In Human Stem Cells Following Exposure To Low Doses Of BPA
Exposing developing tissue to low levels of the plastic bisphenol A, commonly known as BPA, is linked to a greater incidence of prostate cancer in tissue grown from human prostate stem cells, a new st...
Dynavax Chief Scientific Officer Awarded Prestigious Immunology Prize
BERKELEY, CA -- (Marketwired) -- 06/19/13 -- Dynavax Technologies Corporation (NASDAQ: DVAX) announced today that the 2013 Novartis Prize for Basic Immunology has been awarded to Dr. Robert L. Coffma...
Certain Types Of Graft-Versus-Host Disease May Increase Risk Of Death
Joseph Pidala, M.D., M.S., assistant member of the Blood and Bone Marrow Transplant and Immunology programs at Moffitt Cancer Center, and colleagues from the Chronic Graft-Versus-Host Disease Consorti...
'Undruggable' To Druggable: A New Target For Cancer Drug Development
Harvard Stem Cell Institute (HSCI) researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug...
Senescent cells spread the word: non-cell autonomous propagation of cellular senescence
Senescent cells spread the word: non-cell autonomous propagation of cellular senescenceOncogene-induced senescence has been thought to operate cell autonomously. New data establish ‘paracrine senesc...
Transplantation: Alefacept does not reduce risk of T-cell-mediated rejection
Transplantation: The impact of donor CMV infection on kidney graft outcome
Protein Being Studied To Fight Cancer; May Cause Toxicity In Cardiac Cells
A study by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences and the Department of Pharmacology at the University of California, San Diego, shows that a protein called MCL-1, which...
Events
Understand biobanking requirements by encompassing ethical requirements and the latest sampling procedures
Select Biosciences' 4th annual Single Cell Analysis Summit 2013 will build on the overwhelming success of the previous Single Cell events.
SELECTBIO CellTech2014 will feature an integrated program of tracks designed to fully describe the latest trends in analysis of cells, cell-based assays, and high-content phenotypic assays.
Cell Culture World Congress USA
North America’s commercial cell culture event
Advancing cord blood banking & therapeutics
Stem Cells & Regenerative Medicine Congress
North America’s commercial stem cells event
Stem Cells & Cell Therapy Summit
Select Biosciences' Stem Cells & Cell Therapy Summit is focused on providing an up-to-date expansive view of the current marketplace
Oxford Global is proud to present the Biopharma Asia Series taking place on 24th & 25th September 2013 in Singapore.
2nd Annual Cell Culture & Bioprocessing Congress 2013
175 delegates representing leading biotech companies, global pharma organisations and internationally renowned academic institutions
th Annual Next Generation Sequencing Congress 2013
Over 400 Next Generation Sequencing, Genomics, Epigenetics, Genetics, Metagenomics experts from UK, Europe and USA
Companies
Verastem, Inc. (NASDAQ: VSTM) is a clinical-stage biopharmaceutical company focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells. Cancer stem cell...
Phyton Biotech, LLC is a global supplier of high quality paclitaxel and docetaxel API. The company has development and manufacturing facilities near Hamburg, Germany and Va...
Kadimastem is a biotechnology company focusing on the development and industrial commercialization of products based on human pluripotent stem cells. Kadimastemâs technology...
OncoMed is a clinical development-stage biopharmaceutical company focused on discovering and developing first-in-class monoclonal antibody therapeutics targeting cancer stem cells, or CSCs. Our appr...
DiaTech Oncology is a privately held clinical pathology laboratory that offers patient-specific chemotherapy testing to help oncologists determine the best cancer treatment plans...
Sequenta, Inc. is a privately held company developing and commercializing molecular diagnostic assays based on a proprietary sequencing approach to the profiling of T and B cell r...
Ocular Therapeutix, Inc. is a privately held company based in Bedford, MA, focused on the development and commercialization of ophthalmic therapeutic products using its proprietar...
RTI Biologics Inc. is a leading provider of sterile biologic implants for surgeries around the world with a commitment to advancing science, safety and innovation. RTI prep...
As a leader in the field of unrelated marrow and umbilical cord blood transplantation, the National Marrow Donor Program (NMDP) is dedicated to ensuring all patients who need a tr...
RTI Biologics Inc. was formed when Regeneration Technologies Inc. and Tutogen Medical Inc. merged on Feb. 27, 2008. The company is now a leading provider of sterile biologi...
Clinical Trials
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with radiation therapy may kill more tumor ce...
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may...
This phase II trial is studying how well giving erlotinib together with celecoxib works in treating patients with recurrent stage IIIB or stage IV non-small cell lung cancer. Erlotinib and...
Collection of Samples and Data for the National Marrow Donor Program Repository
This protocol will collect blood samples and medical information from patients who have had a bone marrow transplant using cells from an unrelated donor identified through the National Mar...
The purpose of this research study is to determine the effects of ProHema modulated umbilical cord blood units used in transplantation. ProHema modulated cord blood units are being tested...
Stem Cell Collection With Ofatumumab
The goal of this clinical research study is to learn if it is possible to collect stem cells after ofatumumab and chemotherapy treatment. This study will also evaluate side-effects, number...
A Study of Pemetrexed and Gefitinib Versus Gefitinib in Non-Small Cell Lung Cancer (NSCLC)
The purpose of this study is to compare the combination of pemetrexed and gefitinib versus gefitinib alone, in terms of progression-free survival. This study is in participants who have st...
This phase I trial studies the side effects and best dose of PI3K inhibitor BKM120 when given together with carboplatin and pemetrexed disodium in treating patients with stage IV non-small...
This trial is conducted in Europe and North America. The aim of this trial is to investigate if liraglutide treatment can increase the proportion of insulin-independent subjects one year a...
IMA901 in Patients Receiving Sunitinib for Advanced/Metastatic Renal Cell Carcinoma
The primary objective of the phase III study is to investigate whether IMA901 can prolong overall survival in patients with metastatic and/or locally advanced renal cell carcinoma (RCC) wh...
Videos
VIDEO: Blind man gains vision after limbal stem cell transplant surgery
An incredible story: A young man's will to see. A sister's gift of sight. A doctor who made it possible. Click above to watch now! Taylor Binns, a Queen's Un...
Medical and Biotech [MESH] Definitions
Chromosomes, Plant
Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of PLANTS.
Spectral Karyotyping
The simultaneous identification of all chromosomes from a cell by fluorescence in situ hybridization (IN SITU HYBRIDIZATION, FLUORESCENCE) with chromosome-specific florescent probes that are discerned by their different emission spectra.
Chromosomes, Mammalian
Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of MAMMALS.
Stem Cell Transplantation
The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.
Periplasmic Proteins
Proteins found in the PERIPLASM of organisms with cell walls.