Corneal Ulcer - Biotech, Pharma and Life Science Channel
PubMed Articles
Formulation of carbenoxolone for delivery to the skin.
Carbenoxolone (CEX), a semi-synthetic derivative of glycyrrhetinic acid, has previously been used as a disodium salt for the management of dyspepsia and peptic ulcer because of its anti-inflammatory p...
Defect covering of a perforated corneal ulcer with bovine pericardium transplant.
An 89-year-old patient presented in an emergency situation with a perforated corneal ulcer of neurotrophic genesis. An operative treatment with a Tutopatch® was performed. In the course of treatment...
Limbal stem cells (LSCs) derived from human embryonic stem cells (hESCs) hold great potential for cell-based therapies for ocular surface diseases. The cell-based therapies mainly depend on an appropr...
Bisphosphonate-associated osteonecrosis of the external auditory canal.
Background: Osteonecrosis is a benign condition characterised by necrotic exposed bone, and is associated with bisphosphonate use. Osteonecrosis of the external auditory canal is rare, with only a few...
Cilostazol prevents foot ulcers in diabetic patients with peripheral vascular disease.
Diabetic patients are at the high risk of foot ulcerations that may lead to limb amputations with important socio economic impact. Peripheral vascular disease may be frequently associated in diabetes...
OBJECTIVE: To characterise four different intramuscular (IM) anaesthetic protocols, two with alfaxalone and two with alfaxalone in combination with medetomidine in terrestrial tortoises. STUDY DESIGN:...
Balancing the Risk of Eye Irritation from UV-C with Infection from Bioaerosols.
The very aspect (photo-toxicity) that makes short-wavelength ultraviolet (UV) radiation an effective germicidal agent also is responsible for the unwanted side effects of erythema (reddening of the sk...
BACKGROUND: The aim of this study was to compare the visual outcome of femtosecond laser-assisted Descemet stripping automated endothelial keratoplasty (DSAEK) to microkeratome-assisted DSAEK as well...
Disseminated histoplasmosis in South America is associated with AIDS in 70-90 % of cases. It is visceral and cutaneous, compromising the oral, pharynx, and laryngeal mucous membranes. The involvement...
Studies concerning the functional status of the corneal epithelium are of special interest due to its key role in preventing ocular surface disease and corneal infections. In particular, quantitative...
News Articles
Discovery of novel medicine for treatment of chronic wounds
Every 20 seconds, a limb is lost as a consequence of diabetic foot ulcer that does not heal. To date, medical solutions that can change this situation are very limited. In his doctoral thesis Yue Shen...
Novel medicine for chronic wound treatment
Every 20 seconds, a limb is lost as a consequence of diabetic foot ulcer that does not heal. To date, medical solutions that can change this situation are very limited.
NASHVILLE, TN -- (Marketwired) -- 05/20/13 -- Research being presented at an influential patient experience summit demonstrates improved patient outcomes in the prevention of pressure ulcers with the...
Discovery of a novel medicine for the treatment of chronic wounds
(Umea University) Every 20 seconds, a limb is lost as a consequence of a diabetic foot ulcer that does not heal. To date, medical solutions that can change this situation are very limited. In his doct...
Ten Years Later, Intacs a Proven Alternative to Corneal Transplants for Managing Keratoconus
Keratoconus is a non-inflammatory disease of the eye characterized by progressive corneal steepening often resulting in vision loss. In 2003, Dr. Brian Boxer Wachler published h...
GAITHERSBURG, Md., May 15, 2013 /PRNewswire/ -- Sigma-Tau Pharmaceuticals, Inc. announced today that the Company was recognized last evening as a rare disease pioneer at the 30th anniversary cele...
MENLO PARK, Calif., May 14, 2013 /PRNewswire/ -- Avellino Lab USA, developer of the only genetic test available worldwide for Avellino Corneal Dystrophy (ACD), today announced that California-bas...
Tissue Regenix makes progress on commercialisation
Tissue Regenix (LON:TRX) had made significant progress towards commercialisation of its regenerative medical technology over the past year, it said today. The company, which has a patente...
Successful Corneal Transplant With Pre-Loaded Donor Tissue: A First For Massachusetts Eye And Ear
The first successful cornea transplant with donor endothelial tissue preloaded by an eye bank has been performed at Massachusetts Eye and Ear in Boston, Mass. Roberto Pineda II, M.D., Director of the...
Corneal Graft Recovery Following Penetrating Keratoplasty
What are some of the factors that predict corneal graft recovery after severe corneal graft rejection post-PKP? BMC Ophthalmology
Events
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Companies
Gene Signal (www.genesignal.com) is developing a robust pipeline of novel antisense oligonucleotides, proteins and monoclonal antibodies to treat a range of conditions based...
Epidermolysis Bullosa (EB) is a rare genetic disorder characterized by the presence of extremely fragile skin and recurrent blister formation, resulting from minor mechanical fric...
SOOFT italia S.p.A. a Company of OOgroup , is an Italian pharmaceutical firm specialized in the research of new solutions , in carrying out and marketing of products for general a...
SANUWAVE Health, Inc. (www.sanuwave.com) is an emerging regenerative medicine company focused on the development and commercialization of non-invasive, biological response activat...
SightLife and its partner eye banks restore sight to an average of 20 people each day around the globe through the recovery and placement of eye tissue used in cornea transplants....
Ocular Therapeutix, Inc. is a privately held company based in Bedford, MA, focused on the development and commercialization of ophthalmic therapeutic products using its proprietar...
Sigma-Tau Pharmaceuticals, Inc.
Two words to encapsulate the core principles of an entire company. Sigma-Tau Pharmaceuticals, Inc. is a rare corporation dedicated to creating novel therapies for the unmet needs of patients with ra...
RTVue was the first FDA cleared Fourier domain (also known as spectral domain) OCT launched in the United States, and also the first OCT cleared by the U.S. Food and Drug Administration for both corne...
Clinical Trials
The purpose of this investigation is to collect following data in patients given Nexium capsule (Nexium) for long term in usual-post-marketing therapy to prevention of recurrence of gastri...
An RCT on Preventing Pressure Ulcers With Wheelchair Seat Cushions
The primary aim of the proposed multi-site, randomized pressure-reducing wheelchair trial (PRWC-II) is to determine the efficacy of pressure-reducing cushions in preventing sitting-acquire...
A questionnaire composed of items addressing psychological, emotional and social aspects of GERD is developed for Chinese population. We plan to conduct a validation study on this novel di...
To evaluate if intravenous PPI infusion, when administered prior to endoscopy, hastens resolution of bleeding stigmata and thereby facilitates endoscopic examinations and reduces the need...
Characterizing and Diagnosis’s of the Charcot Foot (Charcot Osteoarthropathy) in Diabetic Patients
The condition Charcot foot has been known in more than 130 years, and yet there still remains a large effort to find the cause, diagnostic and medical treatment of the condition. Charcot...
Enzyme Replacement Therapy in Fabry Disease
Fabry disease is an X-linked rare metabolic disease, caused by a deficient activity of the hydrolase α-Galactosidase A, and characterized by a progressive and systematic deposition of gly...
Proton Pump Inhibitor Treatment Stop
The purpose of this study is to determine how many chronic users of antisecretory medication can stop after a test for a bacteria associated with peptic ulcer disease. This is evaluated i...
Screening for Research Subjects With Anterior Segment Diseases
This study will identify patients with anterior segment disease who may be eligible to participate in current or future NEI studies on this disease. Anterior segment disease includes all d...
Effectiveness of Topical Thalidomide to Treat Chronic Graft-Versus-Host-Disease Related Stomatitis
This study will be conducted in two parts. The first part is a pilot study testing the effects of a thalidomide ointment in patients who have developed oral chronic graft-versus-host-disea...
To evaluate the safety and efficacy of BETOPTIC S and Timolol Gel-forming solution in pediatric patients. Patients will dose with study drug at 8 am and 8 pm daily for twelve weeks. Patien...
Videos
corneal ulcer
Dr. Oller explains the diagnosis of corneal ulcer, it's treatment, and important follow up.
Medical and Biotech [MESH] Definitions
Aeromonas Salmonicida
A species of gram-negative bacteria, in the family Aeromonadaceae. It is strictly parasitic and often pathogenic causing FURUNCULOSIS in SALMONIDS and ulcer disease in GOLDFISH.
Corneal Surgery, Laser
Surgical techniques on the CORNEA employing LASERS, especially for reshaping the CORNEA to correct REFRACTIVE ERRORS.
Keratectomy, Subepithelial, Laser-assisted
A surgical technique to correct REFRACTIVE ERRORS of the EYE, such as MYOPIA and ASTIGMATISM. In this method, a flap of CORNEAL EPITHELIUM is created by exposure of the area to dilute alcohol. The flap is lifted and then replaced after laser ablation of the subepithelial CORNEA.
Bowman Membrane
A layer of acellular matrix that lies beneath the CORNEAL EPITHELIUM and above the CORNEAL STROMA. It consists of randomly arranged COLLAGEN fibers in a condensed bed of intercellular substance. It provides stability and strength to the cornea.
Granulomatosis, Orofacial
A condition characterized by persistent or recurrent labial enlargement, ORAL ULCER, and other orofacial manifestations in the absence of identifiable CROHN DISEASE; or SARCOIDOSIS. There is no consensus on whether orofacial granulomatosis is a distinct clinical disorder or an initial presentation of Crohn disease.
