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Coronavirus - Biotech, Pharma and Life Science Channel

21:14 EST 18th January 2017 | BioPortfolio

Coronavirus were first identified in the 1960s, and were named after the crown-like projections on the surface of the virus. They cause respiratory infections in both humans and animals.

Coronaviruses are a large family of viruses that includes viruses that may cause a range of illnesses in humans, from the common cold to SARS. Viruses of this family also cause a number of animal diseases.

Novel coronavirus
This particular strain of coronavirus has not been previously identified in humans. There is very limited information on transmission, severity and clinical impact with only a small number of cases reported thus far.

From September 2012 to date, WHO has been informed of a global total of 38 laboratory confirmed cases of human infection with nCoV (Novel coronavirus) including 20 deaths.  For more inforamtion open http://www.who.int/csr/disease/coronavirus_infections/en/index.html

News Articles [1 Associated News Articles listed on BioPortfolio]

NYBC Scientists Partner In New Discovery for Development of MERS Vaccines

NEW YORK, Nov. 29, 2016 /PRNewswire-USNewswire/ -- New York Blood Center (NYBC) today announced groundbreaking findings toward the development of vaccines for the prevention of Middle East respir...

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Clinical Trials [11 Associated Clinical Trials listed on BioPortfolio]

Assessment of Pharyngeal Carriage of Microorganisms Reponsible for Transmissible Acute Respiratory Infections in HAJJ Pilgrims.

The objective of this project is to study the prevalence of viruses and bacteria responsible for transmissible acute respiratory infections in the respiratory tract of pilgrims returning f...

MERS-CoV Infection tReated With A Combination of Lopinavir /Ritonavir and Interferon Beta-1b

This is a placebo-controlled clinical trial to assess the feasibility, efficacy and safety of a combination of lopinavir/ritonavir and Interferon beta-1b in hospitalized patients with MERS...

Safety, Tolerability, and Pharmacokinetics of SAB-301 in Healthy Adults

Background: Middle East Respiratory Syndrome (MERS) is a newly discovered contagious and sometimes fatal respiratory virus. People often get MERS through close contact with an infected pe...

Phase I, Open Label Dose Ranging Safety Study of GLS-5300 in Healthy Volunteers

The Middle East Respiratory Syndrome Coronavirus (MERS CoV), a virus related to Severe Acute respiratory syndrome coronavirus (SARS CoV), was first recognized as a cause of severe pulmonar...

Saudi Outcomes of ECMO-treated MERS-CoV Patients

A highly pathogenic human coronavirus causing respiratory disease emerged in Saudi Arabia in 2012. This viral infection termed Middle East respiratory syndrome coronavirus (MERS-CoV) is as...

Analysis of Human to Human Transmission of Middle East Respiratory Syndrom Coronavirus (MER-CoV)

This study aimed to analysis the characteristics of MERS transmission and the effect of our institutional personal protective equipment on the controlling the MERS at a tertiary Korean Hos...

Seroprevalence of MERS-CoV IgG in Healthcare Workers

The investigators aim to do serosurvey of healthcare-personnel who had participated in treatment of confirmed patients of Middle-East respiratory syndrome. The investigators collected the ...

SARS Coronavirus Vaccine (SARS-CoV)

Severe acute respiratory syndrome (SARS) is a viral illness that affects the respiratory (breathing) system. The purpose of this study is to evaluate the safety and protective (immune) res...

The Interaction Between Severe Acute Respiratory Distress Syndrome Viral Proteins and Monocytes

Severe acute respiratory syndrome (SARS) is a new threat to public health since November, 2002. The SARS is highly contagious and is believed to be transmitted by person-to-person through ...

Induction of Cytokines in Human Monocytes by SARS-CoV in Adults and Children

Severe acute respiratory syndrome (SARS) is a new emerging infectious disease. Its pathogen is a newly discovered coronavirus (SARS-CoV). The clinical course can be classified to 3 stages:...

PubMed Articles [57 Associated PubMed Articles listed on BioPortfolio]

The First Infant Death Associated With Human Coronavirus NL63 Infection.

Human coronavirus NL63 (HCoV-NL63) primarily infects the upper respiratory tract. However, it may cause severe lower respiratory tract infection, and the clinical course may be severe in immunocomprom...

The Important Role of Lipid Raft-Mediated Attachment in the Infection of Cultured Cells by Coronavirus Infectious Bronchitis Virus Beaudette Strain.

Lipid raft is an important element for the cellular entry of some viruses, including coronavirus infectious bronchitis virus (IBV). However, the exact role of lipid rafts in the cellular membrane duri...

Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding.

The global outbreak of SARS in 2002-2003 was caused by the infection of a new human coronavirus SARS-CoV. The infection of SARS-CoV is mediated mainly through the viral surface glycoproteins, which co...

High Prevalence of Middle East Respiratory Coronavirus in Young Dromedary Camels in Jordan.

Prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) was determined in 45 dromedary camels from two geographically separated herds in Jordan. Virus shedding was only detected in swabs...

Time Course of MERS-CoV Infection and Immunity in Dromedary Camels.

Knowledge about immunity to Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels is essential for infection control and vaccination. A longitudinal study of 11 dam-calf pairs sh...

From plague to MERS: coordinating Australia's response to emerging infectious diseases.

Rapid international travel times and the arrival of new and unexpected infectious disease threats have demonstrated that, for effective communicable disease control, Australia's response needs to be f...

Delayed management of Staphyloccocus aureus infective endocarditis in a Middle East respiratory syndrome coronavirus (MERS-CoV) possible case hospitalized in 2015 in Paris, France.

Viral pathogens among elderly people with acute respiratory infections in Shanghai, China: Preliminary results from a laboratory-based surveillance, 2012-2015.

Acute respiratory infections (ARIs), with viral pathogens as the major contributors, are the most common illnesses worldwide, and increase the morbidity and mortality among the elderly population. The...

Murine Leukemia Virus (MLV)-based Coronavirus Spike-pseudotyped Particle Production and Infection.

Viral pseudotyped particles (pp) are enveloped virus particles, typically derived from retroviruses or rhabdoviruses, that harbor heterologous envelope glycoproteins on their surface and a genome lack...

Drivers of airborne human-to-human pathogen transmission.

Airborne pathogens - either transmitted via aerosol or droplets - include a wide variety of highly infectious and dangerous microbes such as variola virus, measles virus, influenza A viruses, Mycobact...

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Medical and Biotech [MESH] Definitions

A species of CORONAVIRUS causing enteritis in turkeys and pullets.

A species of CORONAVIRUS infecting neonatal calves, presenting as acute diarrhea, and frequently leading to death.

A species of CORONAVIRUS infecting dogs. Onset of symptoms is usually sudden and includes vomiting, diarrhea, and dehydration.

A species in the genus CORONAVIRUS causing the common cold and possibly nervous system infections in humans. It contains hemagglutinin-esterase.

A species in the genus CORONAVIRUS causing the common cold and possibly nervous system infections in humans. It lacks hemagglutinin-esterase.

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