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Cutaneous or mucosal infections - Biotech, Pharma and Life Science Channel

18:58 EST 8th December 2016 | BioPortfolio

PubMed Articles [4659 Associated PubMed Articles listed on BioPortfolio]

Preparing an Adjuvanted Thermoresponsive Gel Formulation for Sublingual Vaccination.

Thermoresponsive gels have unique physicochemical properties that may enable more effective mucosal delivery of active compounds. The thermoresponsive gel (TRG) formulation developed by our group for ...

An easy-to-use wound dressing gelatin-bioactive nanoparticle gel and its preliminary in vivo study.

Beyond promoting hard tissue repairing, bioactive glasses (BGs) have also been proved to be beneficial for wound healing. Nano-scale BGs prepared by sol-gel method were found to have a better performa...

Measuring Telomerase Activity in Senescent Human T Cells Upon Genetic Modification.

Telomerase, a RNA-dependent DNA polymerase that adds telomeric DNA at the 3' ends of eukaryotic chromosomes, is essential for the lifelong preservation of the proliferative potential of antigen specif...

Differentiation of Diverse Progenies of Memory T Cells from Naïve CD8(+) T Cell Precursors.

Following recognition of the cognate antigen, naïve T cells differentiate in a diverse progeny of memory T cells which differ at the phenotypic, gene expression and metabolic level. These molecular d...

Phenotypic and Functional Analysis of Antigen-Specific T Cell Exhaustion.

In some cancers and chronic infections exhausted T cells increase their expression of inhibitory receptors and demonstrate an impaired ability to produce cytokines and to proliferate. Immunological te...

Analysis of T Cell Activation by Confocal Microscopy.

Antigen-recognition by T cells requires the physical association with an antigen presenting cell (APC). At the interface between a T cell and an APC, the orchestrated redistribution of lipids, membran...

Intravital Microscopy Analysis of Hepatic T Cell Dynamics.

T cells play critical roles in controlling hepatotropic viral infections and liver tumors. The protective capacity of these cells is mediated by antigen-experienced effector cells and depends on their...

Hepatitis E Virus in 3 Types of Laboratory Animals, China, 2012-2015.

We found seroprevalences for hepatitis E virus (HEV) of 7.5%, 18.5%, and 83.3% in specific pathogen-free (SPF) laboratory rabbits, monkeys, and pigs, respectively, in China. HEV RNA was detected in 4....

Whole-Genome Characterization and Strain Comparison of VT2f-Producing Escherichia coli Causing Hemolytic Uremic Syndrome.

Verotoxigenic Escherichia coli infections in humans cause disease ranging from uncomplicated intestinal illnesses to bloody diarrhea and systemic sequelae, such as hemolytic uremic syndrome (HUS). Pre...

Ex vivo Cutaneous Bioavailability of Topical Mometasone Furoate in an O/W Preparation.

Mometasone furoate (MMF) is a modern glucocorticoid of the 4th generation, which has been proven not only for inhalation but also for cutaneous treatment. Due to its lipophilic character, it is mainly...

News Articles [2136 Associated News Articles listed on BioPortfolio]

UK launch for Cardiome’s skin infections antibiotic

A one- or two-shot antibiotic has been launched in the UK for the treatment of acute bacterial skin and skin structure infections (ABSSSI) in adults.

2016 Poland Virology and Bacteriology Testing Market: Volume and Sales Forecasts for 100 Tests, Competitive Strategies, Innovative Technologies, Opportunities for Suppliers Prices from USD $4850

This new report from VPG Market Research is designed to help current suppliers and potential market entrants identify and evaluate business opportunities emerging in the infectious disease testing mar...

Vyome Presents on Development of Dual Action Rational Therapeutics (DARTs) to Treat Infections Caused by Antibiotic-Resistant Skin Opportunist Pathogens at Re-Entering Antibacterial Discovery and Development Summit 2016

DARTs Has Potential to Develop Novel Treatments for Gram Positive/Negative Skin Opportunist Pathogens NEW DELHI–(BUSINESS WIRE)–Vyome Biosciences, a clinical-stage specialty biopharmaceuti...

Burkholderia pseudomallei Infections Melioidosis Pipeline Review, H2 2016 Prices from USD $2000

Burkholderia pseudomallei Infections Melioidosis Pipeline Review, H2 2016SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Burkholderia pseudomallei Infection...

Pseudomonas aeruginosa Infections Pipeline Review, H2 2016 Prices from USD $2000

Pseudomonas aeruginosa Infections Pipeline Review, H2 2016SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Pseudomonas aeruginosa Infections Pipeline Review...

Community Acquired MethicillinResistant Staphylococcus aureus CAMRSA Infections Pipeline Review, H2 2016 Prices from USD $2000

Community Acquired MethicillinResistant Staphylococcus aureus CAMRSA Infections Pipeline Review, H2 2016SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Comm...

Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets

The most prevalent route of HIV-1 infection is across mucosal tissues after sexual contact. Langerhans cells (LCs) belong to the subset of dendritic cells (DCs) that line the mucosal epithelia of vagi...

Control of emerging Ebola infections could be aided by new monitoring method

New research on the 2014 Ebola epidemic tracks the rate at which infections move from one district to another and how often infections cross the borders between countries. This study, published in PLO...

20162020 Czech Republic Infectious Disease Testing Market: Volume and Sales Forecasts for 100 Tests, Competitive Strategies, Innovative Technologies, Opportunities for Suppliers Prices from USD $4500

This new report from VPG Market Research is designed to help current suppliers and potential market entrants identify and evaluate business opportunities emerging in the infectious disease testing mar...

Consensus Statement on Surgical Site Infections Released

A new consensus statement on prevention of surgical site infections after gynecologic surgery stresses teamwork, communication, and standardization, using checklists and order sets. Medscape Medical...

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Companies [100 Associated Companies listed on BioPortfolio]

Arsanis, Inc.

Arsanis is committed to the development of monoclonal antibody therapeutics against severe infectious diseases that cannot be controlled with currently available medical treatment...

C3 Jian, Inc.

C3 Jian, founded in 2005, is a clinical-stage biotechnology company developing and commercializing novel products to diagnose, treat and prevent human and animal diseases. C3â€...

Intersect ENT, Inc. '

Intersect ENT, Inc. is dedicated to improving the quality of life for patients with ear, nose and throat conditions. The company markets two steroid releasing implants, PROPEL and...

Telephus Medical LLC

Telephus Medical, located in San Diego, California, is developing a suite of monoclonal antibody products designed to neutralize key staphylococcal enzymes used to attach to host ...

Pursuit Vascular

Headquartered in Maple Grove, Minnesota, Pursuit Vascular, Inc. is developing a family of innovative single-use products designed to protect patients from acquiring life-threateni...

Entasis Therapeutics Inc.

Entasis Therapeutics is developing a portfolio of innovative cures for serious drug-resistant bacterial infections, a global health crisis affecting the lives of millions of patie...

SuctionShield

Made in the USA, SuctionShield safely stores and isolates oral suction tips, such as the Yankauer, between uses to help reduce cross-contamination. It is a disposable, lightweight...

TOPICA Pharmaceuticals, Inc.

TOPICA Pharmaceuticals, Inc. is a privately held clinical research stage pharmaceutical company focused on developing luliconazole for the treatment of onychomycosis, or fungal in...

Cidara Therapeutics, Inc.

Cidara Therapeutics, Inc. is a privately held biopharmaceutical company focused on applying a novel, small molecule immunotherapy platform to treat severe fungal infections in imm...

Avadim Technologies Inc.

Avadim Technologies, Inc., a life science company, was formed in 2007, with a simple vision of improving patient care. Our desire is to transform standard health care practices...

Clinical Trials [2681 Associated Clinical Trials listed on BioPortfolio]

Body Compartment PK for New HIV Pre-exposure Prophylaxis Modalities

The purpose of this study is to determine the ability of new anti-HIV agents to penetrate different body compartments in HIV negative men who have sex with men and transgender women. These...

Safety and Tolerability of Topically Applied Bovine Lung Surfactant on Intact Skin

Bovine Lung Surfactant is used as standard therapy for reducing alveolar surface tension in preterm infants. Here the drug is administered via airways. The use on skin to stimulate the wo...

Specific Respiratory Infections as Triggers of Acute Medical Events

This study will investigate whether there is a population-level association between circulating respiratory viruses and NHS hospital admissions for acute vascular events using data from na...

Phase 3 Multicenter Randomized Double Blind Placebo Controlled Study With Antibacterial Prophylaxis in Azacitidine Treated MDS Patients

Infections are a major and prevalent life-threatening complication among patients with myelodysplastic syndrome (MDS). Currently, the role of prophylactic antibacterial agents after chemot...

Evaluation of Coblation Channeling Treatment for Chronic Tonsillitis.

To evaluate coblation channeling treatment for chronic tonsillitis. Does Tonsillar ablation can create changing in the tonsillar medium for recurrent tonsillar infections and stop the recu...

Fosfomycin i.v. for Treatment of Severely Infected Patients

The purpose of this European, multicentric, prospective, non-interventional study is to document and evaluate the efficacy and safety of the treatment of severely infected patients with in...

Development of the Tool " iPSC " for the Functional Study of Mutations Responsible for Mental Retardation

According to the World Health Organization (WHO), mental retardation (MR) is defined by an intelligence quotient (IQ) < 70 and touches between 1 to 3 % of the general population. Profound ...

Accuracy of a Rapid Diagnostic Test for Cutaneous Leishmaniasis in Morocco

The aim of this study is to estimate the accuracy of CL Detect Rapid Test™ compared to a composite reference standard test (Direct examination of skin smears + PCR test) in patients with...

A Biomarker Study in Advanced Mucosal or Acral Lentiginous Melanoma Receiving Nivolumab in Combination With Ipilimumab

Participants with advanced or metastatic mucosal melanoma (cohort A) and acral lentiginous melanoma (cohort B) eligible for treatment with nivolumab in combination with ipilimumab followed...

ADMSCs for the Treatment of Systemic Sclerosis

Systemic sclerosis (SSc) is a rare autoimmune disease, mainly characterized by cutaneous and visceral fibrosis. Digital ulcer and sclerosing skin are commonly affected on hands, but the tr...

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Medical and Biotech [MESH] Definitions

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous or mucosal papillomas in cattle.

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous and mucosal lesions in rabbits. COTTONTAIL RABBIT PAPILLOMAVIRUS is the type species.

A genus of DNA viruses in the family papillomaviridae, causing mucosal and cutaneous lesions in cats and dogs. Canine oral papillomavirus is the type species.

A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals including rodents. The Leishmania mexicana complex causes both cutaneous (LEISHMANIASIS, CUTANEOUS) and diffuse cutaneous leishmaniasis (LEISHMANIASIS, DIFFUSE CUTANEOUS) and includes the subspecies amazonensis, garnhami, mexicana, pifanoi, and venezuelensis. L. m. mexicana causes chiclero ulcer, a form of cutaneous leishmaniasis (LEISHMANIASIS, CUTANEOUS) in the New World. The sandfly, Lutzomyia, appears to be the vector.

Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.

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