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Cutaneous or mucosal infections - Biotech, Pharma and Life Science Channel

02:08 EST 24th January 2017 | BioPortfolio

PubMed Articles [4649 Associated PubMed Articles listed on BioPortfolio]

Development of a SYBR Green I real-time PCR for the detection of the orf virus.

Orf is a non-systemic, ubiquitous disease of sheep and goats caused by the orf virus (ORFV). ORFV occasionally causes cutaneous lesions in humans in contact with infected animals. In the present study...

Two approaches to the use of benzoc1,2oxaboroles as active fragments for synthetic transformation of clarithromycin().

Clarithromycin (active against Gram positive infections) and 1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole derivatives (effective for Gram negative microbes) are the ligands of bacterial RNA. The antimi...

Acquisition and adaptation of the airway microbiota in the early life of cystic fibrosis patients.

Cystic fibrosis (CF) is a genetic disease in which bacterial infections of the airways play a major role in the long-term clinical outcome. In recent years, a number of next-generation sequencing (NGS...

Mechanism of anti-Vibrio activity of marine probiotic strain Bacillus pumilus H2, and characterization of the active substance.

Vibriosis is a major epizootic disease that impacts free-living and farmed fish species worldwide. Use of probiotics is a promising approach for prevention of Vibrio infections in aquaculture. A probi...

Invasive fungal infections in renal transplant patients: a single center study.

Timely diagnosis of invasive fungal infections (IFI) in renal transplant (RT) patients on immunosuppression is often difficult, jeopardizing their life and graft. We reported IFI and their causative f...

Zika Virus RNA Replication and Persistence in Brain and Placental Tissue.

Zika virus is causally linked with congenital microcephaly and may be associated with pregnancy loss. However, the mechanisms of Zika virus intrauterine transmission and replication and its tropism an...

Vaccine Candidates against Nontypeable Haemophilus influenzae: a Review

Nonencapsulated, nontypeable Hemophilus influenzae (NTHi) remains an important cause of acute otitis and respiratory diseases in children and adults. NTHi bacteria are one of the major causes of respi...

Detection of Multiple Parallel Transmission Outbreak of Streptococcus suis Human Infection by Use of Genome Epidemiology, China, 2005.

Streptococcus suis sequence type 7 emerged and caused 2 of the largest human infection outbreaks in China in 1998 and 2005. To determine the major risk factors and source of the infections, we analyze...

From Visiting a Physician to Expecting Antibiotics: Korean Perspectives and Practices toward Respiratory Tract Infections.

Antibiotic resistance is steadily rising worldwide. Respiratory tract infections (RTIs) are common indications, mostly imprudent, for antibiotic prescriptions in outpatient setting. In Korea, antibiot...

Factors Associated with the Presence and Severity of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Korean Children and Adolescents.

The aim of this study was to identify the risk factors for presence and severity of diabetic ketoacidosis (DKA) at the onset of type 1 diabetes mellitus (T1DM) in Korean children and adolescents. A re...

News Articles [2063 Associated News Articles listed on BioPortfolio]

FDA Grants Priority Review for Genentech’s Actemra® (Tocilizumab) Supplemental Biologics License Application for Giant Cell Arteritis, a Form of Vasculitis

Genentech recently announced positive results from a Phase III clinical trial in giant cell arteritis (GCA) There have been no new therapies for GCA in m...

Antibody responses: A thymic niche for plasma cells

Plasma cells accumulate in the ageing thymus and may provide protection against viral infections.

Immunobiology of Ebola and Lassa virus infections

Severe haemorrhagic fever is a feature of infection with both Ebola and Lassa viruses, but differences in the immune responses induced by infection in each case may have important implications for the...

Enanta Pharmaceuticals to Host Conference Call on February 8 at 4:30 p.m. ET to Discuss Financial Results for its Fiscal First Quarter Ended December 31, 2016

Monday, January 23rd 2017 at 2:17pm UTC WATERTOWN, Mass.–(BUSINESS WIRE)– Enanta Pharmaceuticals, Inc., (NASDAQ: ENTA), a research and development-focused biotechnology company dedicated t...

Improving skin closures for mothers following c-sections

As a way to combat infections after cesarean deliveries, the Society for Maternal-Fetal Medicine conducted a study comparing the effect

GeoVax draws a bead on hep B with therapeutic vaccine deal

GeoVax has partnered with Georgia State University to try to pursue an elusive goal—the development of an effective therapeutic vaccine for hepatitis B virus (HBV) infections. The treatment of chron...

New Information on Infections Related to Heater-Cooler Devices is Revealed by Cardiothoracic Surgeons

Over the last few years, a growing number of serious infections have been linked to bacteria forming in heater-cooler devices (HCDs) used in cardiac surgery operating rooms. In these cases, aerosolize...

Enanta Pharmaceuticals to Host Conference Call on February 8 at 4:30 p.m. ET to Discuss Financial Results for its Fiscal First Quarter Ended December 31, 2016

Enanta Pharmaceuticals, Inc., (NASDAQ: ENTA), a research and development-focused biotechnology company dedicated to creating small molecule drugs for viral infections and liver di...

Safeguards May Be Reducing Serious Catheter Infections

MONDAY, Jan. 23, 2017 -- Improved catheter safety measures in hospitals significantly reduce bloodstream infections and health care costs, a new study indicates. "Safety interventions are a win-win fo...

Study Demonstrates that DecisionDx-Melanoma Test Improves Identification of High Risk Skin Melanoma When Used with AJCC Outcome Prediction Tool

Results published in Journal of the American Academy of Dermatology Castle Biosciences, Inc., a provider of molecular diagnostics to improve cancer treatment decisions, today ...

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Companies [100 Associated Companies listed on BioPortfolio]

Arsanis, Inc.

Arsanis is committed to the development of monoclonal antibody therapeutics against severe infectious diseases that cannot be controlled with currently available medical treatment...

C3 Jian, Inc.

C3 Jian, founded in 2005, is a clinical-stage biotechnology company developing and commercializing novel products to diagnose, treat and prevent human and animal diseases. C3â€...

Intersect ENT, Inc. '

Intersect ENT, Inc. is dedicated to improving the quality of life for patients with ear, nose and throat conditions. The company markets two steroid releasing implants, PROPEL and...

Telephus Medical LLC

Telephus Medical, located in San Diego, California, is developing a suite of monoclonal antibody products designed to neutralize key staphylococcal enzymes used to attach to host ...

Pursuit Vascular

Headquartered in Maple Grove, Minnesota, Pursuit Vascular, Inc. is developing a family of innovative single-use products designed to protect patients from acquiring life-threateni...

Entasis Therapeutics Inc.

Entasis Therapeutics is developing a portfolio of innovative cures for serious drug-resistant bacterial infections, a global health crisis affecting the lives of millions of patie...

SuctionShield

Made in the USA, SuctionShield safely stores and isolates oral suction tips, such as the Yankauer, between uses to help reduce cross-contamination. It is a disposable, lightweight...

TOPICA Pharmaceuticals, Inc.

TOPICA Pharmaceuticals, Inc. is a privately held clinical research stage pharmaceutical company focused on developing luliconazole for the treatment of onychomycosis, or fungal in...

Cidara Therapeutics, Inc.

Cidara Therapeutics, Inc. is a privately held biopharmaceutical company focused on applying a novel, small molecule immunotherapy platform to treat severe fungal infections in imm...

Avadim Technologies Inc.

Avadim Technologies, Inc., a life science company, was formed in 2007, with a simple vision of improving patient care. Our desire is to transform standard health care practices...

Clinical Trials [2734 Associated Clinical Trials listed on BioPortfolio]

A Comparison of Different Community Models of ART Delivery Amongst Stable HIV+ Patients in Two Urban Settings in Zambia

The purpose of this study is to compare the virological and clinical outcomes of patients participating in community models of ART delivery to the standard of care in an urban setting in Z...

Evaluation of the Cost of a Nosocomial Infection With Clostridium Difficile

Clostridium difficile is the first cause of nosocomial infectious diarrhea, due to its mode of transmission and its resistance in the environment. Nosocomiality is defined by the appariti...

Photodynamic Therapy for Treatment of Cutaneous Squamous Cell Carcinoma in Situ

This pilot study will evaluate the effectiveness of using photodynamic therapy for treatment of cutaneous squamous cell in situ (SCCis). Our hypothesis is that PDT will be effective for tr...

A Phase 1 TP-271 Oral PK Single Ascending Dose Study

The purpose of this study is to determine the safety and tolerability of up to 6 different single ascending oral doses of TP-271, ranging from 25 mg to 300 mg, in healthy adult male or fem...

The Human Mucosal Immune Responses to Influenza Virus (SLVP026)

This study will examine the immune responses to the seasonal influenza vaccine in single cells of the nasal passages when compared with cells in circulating blood.

Conventional Endoscopic Mucosal Resection vs Underwater Resection for Colorectal Non-pedunculated Colorectal Lesions

Randomized, comparative and prospective study between Conventional Endoscopic Mucosal Resection for the removal of flat or sessile colorectal lesions without previous attempt to resection.

Laser Fluorescence in Cancer Surgical Treatment

The use of fluorescence for real-time evaluation of organ and tissue vascularization and lymph node anatomy is a recent technology with potential for the surgical treatment of cancer. The ...

A Trial of Enteral Colostrum on Clinical Outcomes in Critically Ill Patients

Enteral administration of immune-modulating nutrients such as glutamine, omega-3 fatty acids, selenium, and antioxidants has been suggested to reduce infections and improve recovery from c...

Clinical Trial of L. Reuteri in Urinary Tract Infections in Non Pregnant Women

RCT to evaluate the safety and efficacy of Lactobacillus reuteri DSM 16666 & Lactobacillus reuteri DSM 17938 to significantly modify the frequency of clinical or bacteriological cure in wo...

COMPLI-PICC: Study on Picclines' Complications

This is a prospective monocentric study of PICC Line complications use in 5 medical and one surgical units of Brest Medical University Hospital. To evaluate the incidence of the following...

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Medical and Biotech [MESH] Definitions

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous or mucosal papillomas in cattle.

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous and mucosal lesions in rabbits. COTTONTAIL RABBIT PAPILLOMAVIRUS is the type species.

A genus of DNA viruses in the family papillomaviridae, causing mucosal and cutaneous lesions in cats and dogs. Canine oral papillomavirus is the type species.

A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals including rodents. The Leishmania mexicana complex causes both cutaneous (LEISHMANIASIS, CUTANEOUS) and diffuse cutaneous leishmaniasis (LEISHMANIASIS, DIFFUSE CUTANEOUS) and includes the subspecies amazonensis, garnhami, mexicana, pifanoi, and venezuelensis. L. m. mexicana causes chiclero ulcer, a form of cutaneous leishmaniasis (LEISHMANIASIS, CUTANEOUS) in the New World. The sandfly, Lutzomyia, appears to be the vector.

Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.

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