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Cutaneous or mucosal infections - Biotech, Pharma and Life Science Channel

05:38 EST 7th February 2016 | BioPortfolio

PubMed Articles [4786 Associated PubMed Articles listed on BioPortfolio]

Toward a high-performance management system in health care, part 4: Using high-performance work practices to prevent central line-associated blood stream infections-a comparative case study.

Central line-associated bloodstream infections (CLABSIs) are among the most harmful health care-associated infections and a major patient safety concern. Nationally, CLABSI rates have been reduced thr...

Novel antibacterial ocular prostheses: Proof of concept and physico-chemical characterization.

Discouraging bacterial colonization of ocular biomaterials and implants is a significant challenge in ophthalmology as infections often lead to the need for secondary surgery, with associated risks an...

Anti-biofilm activity of chitosan gels formulated with silver nanoparticles and their cytotoxic effect on human fibroblasts.

The development of multi-species biofilms in chronic wounds is a serious health problem that primarily generates strong resistance mechanisms to antimicrobial therapy. The use of silver nanoparticles ...

Different faces of Nocardia infection in renal transplant recipients.

Nocardia infections are an uncommon but important cause of morbidity and mortality in renal transplant recipients. The present study was carried out to determine the spectrum of Nocardia infections in...

Morphologic characterization of hamartomatous gastrointestinal polyps in Cowden syndrome, Peutz-Jeghers syndrome, and juvenile polyposis syndrome.

The morphologic features of the gastrointestinal polyps in hamartomatous polyposis syndromes are poorly defined. Our aim was to better characterize the gastrointestinal hamartomas in these syndromes. ...

Sex differences in HIV-1-mediated immunopathology.

The article reviews our current knowledge regarding the role of sex and sex hormones in regulating innate immune responses to viral infections, which may account for the described sex differences in i...

Experimental treatment strategies in primary cutaneous T-cell lymphomas.

Cutaneous T-cell lymphoma (CTCL) comprises a heterogeneous group of malignancies derived from skin-homing or resident T cells. Effective treatments are limited, thus new therapies are in development t...

O-024 Improving Pneumococcal Immunization Rates Among Immunocompromised Adolescent Patients with Inflammatory Bowel Disease.

Streptococcus pneumoniae is a leading cause of severe infections, including pneumonia and meningitis, among immunocompromised patients. The administration of both the 13-valent pneumococcal conjugate ...

O-012 The Intestinal Wound Regeneration Modulates Mucosal Microenvironment to Stimulate Expansion of a Local Pro-restitutive Microbiota.

Ulcerative colitis and Crohn's disease frequently cause epithelial damage in the intestine, leading to gut inflammation accompanied by areas of ulceration. The regeneration of damaged mucosa as well a...

O-011 Paneth Cell Phenotypes Define a Subtype of Pediatric Crohn's Disease Through Alterations in Host-Microbial Interactions.

To identify and develop novel targeted therapies for complex diseases such as Crohn's disease (CD), functional subtypes rooted in pathogenesis must be defined. One candidate method to subtype CD is to...

News Articles [1861 Associated News Articles listed on BioPortfolio]

scPharmaceuticals’ drug/device combo aims at replacing IVs in antibiotic drug delivery

scPharmaceuticals has raised $3.6 million in what looks to be a bridge financing round for its drug/device combo that could replace IV use in treating heart failure and infections.

Enyo Pharma closes €22mm Series A

Enyo Pharma SAS (therapies for acute and chronic viral infections) raised €22mm ($24mm) in its Series A financing led by returning shareholder Sofinnova Partners, which was joined by Morningside and...

Myconostica announces successful continuation of D round with investment by Medac

Myconostica Ltd, the UK-based medical diagnostic company developing and commercialising rapid and highly specific tests for life-threatening fungal infections, today announces the completion of an inv...

Vernacare receives Royal Seal of Approval

Bolton-based Vernacare was invited to the event after winning the Queen's Award for Enterprise for its innovative wash bowl, which was developed with the help from NHS clinicians.It aims to meet deman...

Redx bids to launch second spin-out

Pharmaceutical business Redx Pharma is bidding to launch a new company focused on developing drugs to combat resistance to antibiotics and new medicines to tackle viral infections. Led by chief exec...

Euprotec collaborates with Fulhold and New Jersey Medical School in developing a novel agent to prevent multi-drug resistant skin infections

The US Department of Defence (DoD) has awarded to New Jersey Medical School-UMDNJ and an international consortium consisting of Euprotec and Fulhold Ltd a $1.53 million contract (W81XWH-12-2-0076) to ...

Redx raises £6m and takes new division to AZ's Alderley Park site

Redx Pharma is to open a new research and development facility at AstraZeneca’s Alderley Park site in Cheshire.The new venture, Redx Anti-Infectives, will create 119 high value science jobs at...

F2G Ltd and The University of Manchester Announce a new €6.1million project to develop new antifungal agents to treat resistant fungal infections.

F2G Ltd, a privately-held antifungal drug discovery and development company and The University of Manchester, today announced the commencement of a 6.1 million euro EU-funded proje...

Perfectus Biomed seals £100k growth funding

A fledging medical testing company has secured £100,000 investment to expand its research team and make other strategic investments.Perfectus Biomed, based at Sci-Tech Daresbury, Cheshire, rec...

Alabama pays town’s residents to undergo TB testing

The US state of Alabama, struggling to gain control of a tuberculosis epidemic around the small town of Marion, has discovered more than 100 infections after offering money to citizens to undergo... ...

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Companies [98 Associated Companies listed on BioPortfolio]

Intersect ENT, Inc. '

Intersect ENT, Inc. is dedicated to improving the quality of life for patients with ear, nose and throat conditions. The company markets two steroid releasing implants, PROPEL and...

Telephus Medical LLC

Telephus Medical, located in San Diego, California, is developing a suite of monoclonal antibody products designed to neutralize key staphylococcal enzymes used to attach to host ...

Pursuit Vascular

Headquartered in Maple Grove, Minnesota, Pursuit Vascular, Inc. is developing a family of innovative single-use products designed to protect patients from acquiring life-threateni...

Entasis Therapeutics Inc.

Entasis Therapeutics is developing a portfolio of innovative cures for serious drug-resistant bacterial infections, a global health crisis affecting the lives of millions of patie...

SuctionShield

Made in the USA, SuctionShield safely stores and isolates oral suction tips, such as the Yankauer, between uses to help reduce cross-contamination. It is a disposable, lightweight...

TOPICA Pharmaceuticals, Inc.

TOPICA Pharmaceuticals, Inc. is a privately held clinical research stage pharmaceutical company focused on developing luliconazole for the treatment of onychomycosis, or fungal in...

Cidara Therapeutics, Inc.

Cidara Therapeutics, Inc. is a privately held biopharmaceutical company focused on applying a novel, small molecule immunotherapy platform to treat severe fungal infections in imm...

Avadim Technologies Inc.

Avadim Technologies, Inc., a life science company, was formed in 2007, with a simple vision of improving patient care. Our desire is to transform standard health care practices...

Avadim Technologies, Inc.

Avadim Technologies, Inc., a life science company, was formed in 2007, with a simple vision of improving patient care. Our desire is to transform standard health care practices...

Conkwest, Inc.

Conkwest is an innovative immuno-oncology company that is developing and commercializing a portfolio of highly potent and selective cellular therapies for the treatment of cancers...

Clinical Trials [2199 Associated Clinical Trials listed on BioPortfolio]

ADDITIONAL GASTRIC CORPUS BIOPSIES IN H PYLORI DETECTION

There are controversies about the best sites -biopsy based -tests for H pylori associated gastritis. The study is designed to evaluate the optimal site of gastric mucosal biopsy for identi...

New Strategies Against Cutaneous Squamous Cell Carcinoma

The gold treatment for local invasive cutaneous squamous cell carcinoma is surgical excision. Nevertheless, surgery is not always an option as a consequence of the age and/or the health st...

Evaluation of Low-dose Darunavir in a Switch Study

This is a switch study to assess the non-inferiority (in terms of efficacy and safety) of darunavir (boosted with ritonavir, DRV/r 400mg/100mg daily) when compared with lopinavir (boosted ...

Sharklet Catheter Study

The aim of this study is to determine if the Sharklet catheter, with its unique coating, reduces infections in participants, when compared to a standard catheter.

Optimizing Sysmex Technology as an Innovative Tool to Differentiate Between Malaria (PALUdism) and BACterial Infections in a Malaria Endemic Region

Severe malaria and bacterial Blood Stream Infections (bBSI) are impossible to differentiate clinically. This poses a particular threat in low resource areas, where bBSI is often not diagno...

Assessing a Endoscopic Mucosal Resection Site Using Different Endoscopic Imaging Methods

The purpose of this study is to compare the accuracy of using different endoscopic imaging technique (white light, white light with near focus, narrow band imaging (NBI), NBI with near foc...

Efficacy of AFL-assisted PDT in Microinvasive Squamous Cell Carcinoma

Surgical excision is the standard treatment for cutaneous SCC. However, many patients diagnosed with SCC are elderly and ineligible for surgery. Ablative fractional laser- assisted photody...

Safety and Therapeutic Efficacy of the VRC01 Antibody in Patients Who Initiated Antiretroviral Therapy During Early Acute HIV Infection

The study will evaluate the safety and therapeutic efficacy of the human monoclonal antibody (mAb) VRC-HIVMAB060-00-AB (VRC01), when administered during analytic treatment interruption (AT...

Safety and TDM of Continuous Infusion Vancomycin Through Continuous Renal Replacement Therapy Solution

The purpose of this investigation is to evaluate the safety of delivering continuous infusion (CI) vancomycin in pediatric CRRT by utilizing CI via by mixing the anti-microbial into the CR...

Mast Cells in Acid-induced Intestinal Permeability

This is a randomized, double-blind, cross-over study in healthy volunteers. In the first part, the duodenum of the participants will be perfused with acid or saline, during which intragast...

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Medical and Biotech [MESH] Definitions

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous or mucosal papillomas in cattle.

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous and mucosal lesions in rabbits. COTTONTAIL RABBIT PAPILLOMAVIRUS is the type species.

A genus of DNA viruses in the family papillomaviridae, causing mucosal and cutaneous lesions in cats and dogs. Canine oral papillomavirus is the type species.

A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals including rodents. The Leishmania mexicana complex causes both cutaneous (LEISHMANIASIS, CUTANEOUS) and diffuse cutaneous leishmaniasis (LEISHMANIASIS, DIFFUSE CUTANEOUS) and includes the subspecies amazonensis, garnhami, mexicana, pifanoi, and venezuelensis. L. m. mexicana causes chiclero ulcer, a form of cutaneous leishmaniasis (LEISHMANIASIS, CUTANEOUS) in the New World. The sandfly, Lutzomyia, appears to be the vector.

Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.

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