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Cutaneous or mucosal infections - Biotech, Pharma and Life Science Channel

19:46 EDT 16th August 2017 | BioPortfolio

PubMed Articles [4809 Associated PubMed Articles listed on BioPortfolio]

Human perinatal immunity in physiological conditions and during infection.

The intrauterine environment was long considered sterile. However, several infectious threats are already present during fetal life. This review focuses on the postnatal immunological consequences of ...

Systemic and microcirculatory effects of blood transfusion in experimental hemorrhagic shock.

The microvascular reperfusion injury after retransfusion has not been completely characterized. Specifically, the question of heterogeneity among different microvascular beds needs to be addressed. In...

Development of a SYBR Green I real-time PCR for the detection of the orf virus.

Orf is a non-systemic, ubiquitous disease of sheep and goats caused by the orf virus (ORFV). ORFV occasionally causes cutaneous lesions in humans in contact with infected animals. In the present study...

Two approaches to the use of benzoc1,2oxaboroles as active fragments for synthetic transformation of clarithromycin().

Clarithromycin (active against Gram positive infections) and 1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole derivatives (effective for Gram negative microbes) are the ligands of bacterial RNA. The antimi...

Acquisition and adaptation of the airway microbiota in the early life of cystic fibrosis patients.

Cystic fibrosis (CF) is a genetic disease in which bacterial infections of the airways play a major role in the long-term clinical outcome. In recent years, a number of next-generation sequencing (NGS...

Mechanism of anti-Vibrio activity of marine probiotic strain Bacillus pumilus H2, and characterization of the active substance.

Vibriosis is a major epizootic disease that impacts free-living and farmed fish species worldwide. Use of probiotics is a promising approach for prevention of Vibrio infections in aquaculture. A probi...

Endogenous endophthalmitis due to Roseomonas mucosa presenting as a subretinal abscess.

Endogenous bacterial endophthalmitis is an infrequently reported entity. Although Roseomonas mucosa has been reported to cause systemic infections in immunosuppressed individuals, ocular infection due...

Management of respiratory tract infections in young children-A qualitative study of primary care providers' perspectives.

Respiratory tract infections in young children are the most common cause of general practice visits in Australia. Despite the availability of clinical practice guidelines, the treatment and management...

Cytotoxicity and anti-Leishmania amazonensis activity of Citrus sinensis leaf extracts.

Leishmania amazonensis is the main agent of diffuse cutaneous leishmaniasis, a disease characterized by lesional polymorphism and the commitment of skin surface. Previous reports demonstrated that the...

Wound healing activity of Pluchea indica leaf extract in oral mucosal cell line and oral spray formulation containing nanoparticles of the extract.

Pluchea indica (L.) Less (Asteraceae) is an herb used as a traditional medicine for wound healing. The chemical compounds found in Pluchea indica leaves are phenolic acids, flavonoids, anthocyanins an...

News Articles [1929 Associated News Articles listed on BioPortfolio]

Perrigo gets FDA approval for generic Mycolog II cream

David SalazarThe drug is indicated to treat cutaneous candidiasis. It had a U.S. market size of $93 million for the 12 months ended June 2017. read more

FDA Grants Priority Review for Seattle Genetics’ Adcetris in Cutaneous T-Cell Lymphoma

BOTHELL, Wash.–(BUSINESS WIRE)–Seattle Genetics, Inc. (Nasdaq: SGEN) announced today that the U.S. Food and Drug Administration (FDA) has accepted for filing a supplemental Biologics Lice...

FDA announces recall of some liquid pharmaceutical products

(HealthDay)—The U.S. Food and Drug Administration has announced a recall of numerous liquid pharmaceutical products because of possible bacterial contamination that could cause severe infections in ...

Regeneron discontinues clinical development of antibody for respiratory virus

Regeneron Pharmaceuticals has announced plans to discontinue further clinical development of its antibody, suptavumab, for respiratory syncytial virus, as it has not met the primary endpoint of preven...

TetraLogic Pharmaceuticals TLOG Financial and Strategic SWOT Analysis Review [Report Updated: 07082017] Prices from USD $300

SummaryTetraLogic Pharmaceuticals TetraLogic is a biopharmaceutical company that research and develops novel small molecule therapeutics in the areas of oncology and infectious diseases. The company's...

Americans Injuring Themselves Grooming Pubic Hair

WEDNESDAY, Aug. 16, 2017 -- Should you consider trimming or shaving "down there," proceed with care -- a new study finds injuries tied to pubic hair grooming are more common than you might think. Cuts...

Ouch! Americans Injuring Themselves Grooming Pubic Hair

WEDNESDAY, Aug. 16, 2017 -- Should you consider trimming or shaving "down there," proceed with care -- a new study finds injuries tied to pubic hair grooming are more common than you might think. Cuts...

FDA Accepts Supplemental Biologics License Application and Grants Priority Review for ADCETRIS® (Brentuximab Vedotin) in Cutaneous T-Cell Lymphoma

-Supplemental BLA Based on Clinical Trial Results from the Phase 3 ALCANZA and Phase 2 Investigator-Sponsored Studies in CTCL- -FDA Previously Granted ADCETRIS Breakthrou...

Genetic Variance is Key to Individual Immune Response

Ever wonder why your friend, co-worker, or partner doesn’t get as sick as you, even though they caught the same “bug” you did? Maybe they made some Faustian bargain that affords them greater pro...

Aradigm gets NIH grant for Linhaliq in pulmonary non-tuberculous mycobacteria treatment

The National Institute of Allergy and Infectious Diseases (NIAID) and National Institutes of Health (NIH) have awarded a Small Business Initiative Research (SBIR) grant to Aradigm to study the treatme...

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Companies [107 Associated Companies listed on BioPortfolio]

Symbiomix Therapeutics, LLC

Symbiomix (sim-bye-OH-mix) is a biopharmaceutical company bringing innovative medicines to market for prevalent gynecological infections that can have serious health consequences....

Osprey Medical Inc.

Osprey Medical's core technologies originated from research conducted by Dr David Kaye at Melbourne’s Baker IDI Heart and Diabetes Institute. Osprey is focused on improving p...

HCA Healthcare, Inc.

Nashville-based HCA Healthcare is one of the nation's leading providers of healthcare services, operating 172 locally managed hospitals and 119 freestanding surgery centers in 20 ...

HCA Healthcare

Nashville-based HCA Healthcare is one of the nation's leading providers of healthcare services, operating 174 locally managed hospitals and 119 freestanding surgery centers in 20 ...

Ralexar Therapeutics, Inc.

Ralexar Therapeutics, Inc. is a privately-held specialty pharmaceutical company founded in January 2014 and based in Malvern, Pennsylvania. The company is developing topical and s...

PAVmed Inc.

PAVmed Inc. (Nasdaq: PAVM, PAVMW) is a highly differentiated, multi-product medical device company employing a unique business model designed to advance products from concept to c...

Appili Therapeutics Inc.

Appili is dedicated to identifying, acquiring and advancing novel therapeutics for infectious disease. The company has two anti-infective programs, ATI-1501 and ATI-1503, in its p...

Affinivax, Inc.

Affinivax is advancing a next generation vaccine technology platform to enable the development of vaccines that provide the highest level of protection against challenging infecti...

Discuva

Discuva aims to revolutionise the treatment of disease caused by bacterial infection by discovering and developing new antibiotics against highly drug-resistant pathogens. The com...

Arsanis, Inc.

Arsanis is committed to the development of monoclonal antibody therapeutics against severe infectious diseases that cannot be controlled with currently available medical treatment...

Clinical Trials [3037 Associated Clinical Trials listed on BioPortfolio]

Correlation Between Premature Rupture of Membranes and Early-onset Neonatal Infections

This study hypothesizes that early-onset neonatal Infections are related to premature rupture of membrane (PROM) and that early intervention can improve the prognosis of newborns. The obje...

TB Sequel: Pathogenesis and Risk Factors of Long-term Sequelae of Pulmonary TB

This is an observational cohort study. Pulmonary tuberculosis (TB) patients will be enrolled at the time of TB diagnosis and prospectively followed for at least two years after TB-treatmen...

Chromoendoscopy in Inflammatory Bowel Disease

Patients with longstanding ulcerative colitis (inflammatory bowel disease, IBD) have increased risk of developing colorectal cancer (CRC) when compared with that of the general population....

Biofilm Infection in Adults and Children Burn Injury

The objective of the study is to analyze the different implications (such as graft loss and conversion of indeterminate depth burns) of biofilm infections in burn patients. Additionally, i...

Pharmacological Comparison of Continuous and Intermittent Infusions of Cloxacillin

Our objective is to establish pharmacological equivalence of intermittent and continuous infusion of cloxacillin during methicillin-susceptible Staphylococcus aureus (MSSA) bone and joint ...

Impact of Oral Hygiene Gels on Peri-implant Mucositis

Peri-implant mucositis is abnormal inflammation occurring around dental implants, increasing the risk of loss of bone support. The purpose of this study is to evaluate the impact of brushi...

Effect of OM-85 on Respiratory Tract Infections and Adenoid Tissue in Children With Adenoid Hypertrophy

Clinical research question: Can OM-85 reduce the recurrence of respiratory tract infections (RTIs) in children with AH by stimulating the immunological response of the host and therefore, ...

Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations

To evaluate the efficacy of Rapamycin in extended cervicofacial lymphatic malformations in pediatric patients. Rapamycin is administered oral for a 6 month period. The success rate is det...

Endoscopic Mucosal Resection and Cellular Matrix

This study is being done to assess the use of scaffold products in promoting constructive healing as determined by the ability of the resection site to lift during follow-up.

Ipilimumab and Nivolumab as Adjuvant Treatment of Mucosal Melanoma

The trial is a single arm phase II clinical trial of Ipilimumab and Nivolumab in patients with resected mucosal melanoma. Ipilimumab (1 mg/kg) and Nivolumab (3 mg/kg) will be administered ...

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Medical and Biotech [MESH] Definitions

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous or mucosal papillomas in cattle.

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous and mucosal lesions in rabbits. COTTONTAIL RABBIT PAPILLOMAVIRUS is the type species.

A genus of DNA viruses in the family papillomaviridae, causing mucosal and cutaneous lesions in cats and dogs. Canine oral papillomavirus is the type species.

Fungal infections caused by TRICHOSPORON that may become systemic especially in an IMMUNOCOMPROMISED HOST. Clinical manifestations range from superficial cutaneous infections to systemic lesions in multiple organs.

A subset of T-lymphocytes that are present in large numbers at MUCOUS MEMBRANES and respond to INFECTIONS. They express a conserved invariant T-CELL RECEPTOR ALPHA-CHAIN that enables them to respond to infections by sensing RIBOFLAVIN metabolites of pathogens.

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