Cutaneous or mucosal infections - Biotech, Pharma and Life Science Channel

02:24 EST 3rd March 2015 | BioPortfolio

PubMed Articles [5038 Associated PubMed Articles listed on BioPortfolio]

Complications of mammalian target of rapamycin inhibitor anticancer treatment among patients with tuberous sclerosis complex are common and occasionally life-threatening.

The aim of this study was to evaluate the most common adverse events (AEs) linked to everolimus therapy, a mammalian target of rapamycin (mTOR) inhibitor, in children and adolescents with tuberous scl...

A randomized controlled trial of factors influencing fire occurrence during laser surgery of cadaveric rodents under simulated mask anesthesia.

Objective-To determine whether face mask fit during anesthesia affects the occurrence of fire episodes during laser surgery in nonintubated cadaveric rodents under volatile anesthesia. Design-Adaptive...

Preventing group B streptococcal infections in newborns.

Despite advances in intrapartum antibiotic prophylaxis (IAP), group B streptococcal infection continues to be a predominant cause of early-onset disease in neonates. About 2% of neonates exposed to gr...

Evaluation of gold nanoparticle based lateral flow assays for diagnosis of enterobacteriaceae members in food and water.

Lateral flow immunoassays (LFIAs) are advantageous over conventional detection methods in terms of their simplicity and rapidity. These assays have been reported using various types of labels but coll...

Which Multidrug-Resitant Bacteria are Emerging in Patients with Hematological Malignancies?: One-Year Report.

The aim of this retrospective, observational study was to evaluate the outcomes of bacteremia attacks during neutropenic episodes caused by chemotherapy in patients with hematological cancers by asses...

Gender moderates the relationship between impulsivity and sexual risk-taking in a cocaine-using psychiatric outpatient population.

Adults who abuse substances are at increased risk for contracting sexually transmitted infections, including HIV. Within this population, sexual risk behaviors have been associated with increased impu...

Effectiveness of Health Education Teachers and School Nurses Teaching Sexually Transmitted Infections/Human Immunodeficiency Virus Prevention Knowledge and Skills in High School.

We examined the differential impact of a well-established human immunodeficiency virus (HIV)/sexually transmitted infections (STIs) curriculum, Be Proud! Be Responsible!, when taught by school nurses ...

Premarital sexual activity among unmarried adolescents in northern Ethiopia: a cross-sectional study.

Sexual activity can expose adolescents to the risks of unintended pregnancy, unsafe abortion and sexually transmitted infections including HIV/AIDS. This risk is magnified for girls. The objective of ...

Autoimmune encephalitis and its relation to infection.

Encephalitis, an inflammatory condition of the brain that results in substantial morbidity and mortality, has numerous causes. Over the past decade, it has become increasingly recognized that autoimmu...

Splice-Correction Strategies for Treatment of X-Linked Agammaglobulinemia.

X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disease caused by mutations in the gene coding for Bruton's tyrosine kinase (BTK). Deficiency of BTK leads to a developmental block in B...

News Articles [1831 Associated News Articles listed on BioPortfolio]

House Call Medicine Helps Patients Receive Treatment While Avoiding the Hassles and Potential Risks of an Urgent Care Facility

LOS ANGELES, March 2, 2015 /PRNewswire/ -- When someone gets sick, their first course of action is usually to head to a primary care physician or an urgent care facility to receive treatment. Aft...

Chimerix Drug Shows Promise As Virus Fighter for Transplant Patients

The commonly found adenovirus poses little problem for healthy people, whose immune systems can fight the respiratory and gastrointestinal infections the virus can cause. But in bone marrow and organ ...

Actavis Receives Approval from the European Commission for XYDALBA™ (dalbavancin)

DUBLIN, March 2, 2015 /PRNewswire/-- Actavis plc (NYSE: ACT) today announced that the European Commission has granted Actavis' subsidiary Durata Therapeutics International B.V., marketing au...

Synthetic Biologics Announces Two Poster Presentations of Novel Monoclonal Antibody Combination for Treatment of Whooping Cough (Pertussis) at ECCMID 2015

ROCKVILLE, Md., March 2, 2015 /PRNewswire/ -- Synthetic Biologics, Inc. (NYSE MKT: SYN), a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting...

Intractable C. Difficile Infection Linked to Multiple Care Settings

(MedPage Today) -- Evidence indicates many infections occur outside the hospital.

Sierra Leone vice president places himself in Ebola quarantine

FREETOWN (Reuters) - Sierra Leone's Vice President Samuel Sam-Sumana said on Saturday that he had placed himself in a 21-day quarantine after one of his bodyguards died of Ebola amid a worrying recent...

MicuRx Pairs US Phase II Trial of Novel Antibiotic with China Test

MicuRx Pharma, a US-China company, was granted FDA approval to begin a US Phase II trial of its lead molecule, MRX-I, a novel oral antibiotic for drug-resistant Gram-positive infections. MicuRx, which...

Salmonella and Campylobacter show significant levels of resistance to common antimicrobials in humans and animals

Treatment options for some of the most common food-borne infections are decreasing, as types of bacteria (called 'isolates') continue to show resistance to antimicrobial drugs. For example, multi-drug...

Ephraim McDowell Regional Medical Center Unveils Xenex Germ Killing Robot

Ephraim McDowell Regional Medical Center (EMRMC) is taking a leading role among Kentucky hospitals with the purchase of a germ-zapping robot. The Xenex robot is capable of moving ...

Hepatitis C Infections in Hospitals Show Need for Tight Infection Control Practices

FRIDAY, Feb. 27, 2015 -- Two cases of hepatitis C infection that occurred during routine surgeries highlight the need for hospitals to tighten infection control to prevent more transmissions, official...

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Companies [88 Associated Companies listed on BioPortfolio]

Global Virus Network

The Global Virus Network (GVN) is an independent organization comprised of leading medical virologists from Argentina, Australia, Canada, China, Germany, India, Ireland, Israel, I...

Viamet Pharmaceuticals Inc.

Viamet is a biopharmaceutical company focused on the discovery, development and commercialization of novel antifungal agents based on its proprietary metalloenzyme medicinal chemi...

Mucosis B.V.

Mucosis B.V. (Mucosis) is a clinical-stage biotechnology company using a proprietary technology platform to develop next-generation needle-free human vaccines for infectious disea...

Global Virus Network (GVN)

The Global Virus Network (GVN) is an independent, not for profit organization, comprised of leading medical virologists from Argentina, Australia, Belgium, Canada, China, France, ...

Cell Medica Limited

Cell Medica is a cellular therapeutics company engaged in the development, manufacturing and marketing of T cell immunotherapy approaches for the treatment of infections and cance...

Cidara Therapeutics, Inc.

Cidara Therapeutics, Inc. is a privately held biopharmaceutical company focused on applying a novel, small molecule immunotherapy platform to treat severe fungal infections in imm...

Meridian Bioscience Inc.

Meridian is a fully integrated life science company that develops, manufactures, markets and distributes a broad range of innovative diagnostic test kits, purified reagents and re...

StableLab

StableLab’s equine blood test detects and measures Serum Amyloid A (SAA), a major acute phase protein, delivering lab-accurate results at the horse’s side, enabli...

virtuwell

virtuwell is a 24/7 online clinic developed by HealthPartners, the largest consumer-governed nonprofit health care organization in the nation with a mission to improve health and ...

Stemedica Cell Technologies Inc.

Stemedica Cell Technologies Inc. is a specialty biopharmaceutical company that is committed to the manufacturing and development of best-in-class, allogeneic, adult stem cells and...

Clinical Trials [1664 Associated Clinical Trials listed on BioPortfolio]

Dose Proportionality of TFV-DP After a Single Dose of GS-7340 in Women

Purpose: The purpose of this study is to characterize the dose-proportionality in the distribution of tenofovir alafenamide (TAF) and tenofovir (TFV) in plasma and mucosal tissues, and ...

Gene Expression in HIV and Tuberculosis Co-infection

Background: - Tuberculosis (TB) infection is particularly deadly when it happens in people who are also infected with the human immunodeficiency virus (HIV). However, not much is known ab...

Durability of Adherence in Self-Management of HIV (The DASH Study)

Adherence to highly active antiretroviral therapy (HAART) is critical to successful treatment of HIV. This study will test an intervention that helps people infected with HIV take all thei...

Identification of Novel Biomarkers of Cervicovaginal Mucosal Inflammation

This study investigates the response of vaginal and cervical tissue after exposure to three vaginal products: hydroxyethyl cellulose (HEC) placebo, nonoxynol-9 (N9) and imiquimod (IMQ) cr...

Prospective Study on Severe Infections on Acute Myeloid Leukemia (AML) Patients

All patients receiving induction, consolidation and salvage chemotherapy, and autologous or allogeneic stem cell transplantation according to a strategy defined in the GIMEMA AML1310 proto...

Prospective Study to Optimize Vancomycin Dosing in Children and Adults Using Computer Software

We will compare the percentage of patients having therapeutic vancomycin serum concentrations after current standard dosing, after dosing with our software. We will also include therapeut...

Comparison of Alcoholic Chlorhexidine 2% Versus Alcoholic Povidone Iodine for Infections Prevention With Cardiac Resynchronization Therapy Device Implantation

Heart Failure (HF) with systolic dysfunction is associated with a poor prognosis in the long term despite the use of many effective drug treatment in reducing morbidity and mortality. In t...

Study of Intestinal Permeability in Patients With Anorexia Nervosa

In healthy humans, the intestinal mucosa acts as an absorption organ and a defensive barrier preventing the passage of toxic substances from the intestinal lumen to the blood stream. Malnu...

Duke Lupus Registry

Lupus is a systemic autoimmune disease that can present with many varied symptoms, including joint pain, fevers, kidney disease, and rashes. Lupus can affect anyone, but it is most common...

The Effect of Shear- Force at the Skin in Patients With Diabetes Mellitus

1. The objective of this study is to acquire knowledge about the development of reactive hyperaemia and inflammatory responses of the skin after shear- force and pressure loading...

Medical and Biotech [MESH] Definitions

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous or mucosal papillomas in cattle.

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous and mucosal lesions in rabbits. COTTONTAIL RABBIT PAPILLOMAVIRUS is the type species.

A genus of DNA viruses in the family papillomaviridae, causing mucosal and cutaneous lesions in cats and dogs. Canine oral papillomavirus is the type species.

A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals including rodents. The Leishmania mexicana complex causes both cutaneous (LEISHMANIASIS, CUTANEOUS) and diffuse cutaneous leishmaniasis (LEISHMANIASIS, DIFFUSE CUTANEOUS) and includes the subspecies amazonensis, garnhami, mexicana, pifanoi, and venezuelensis. L. m. mexicana causes chiclero ulcer, a form of cutaneous leishmaniasis (LEISHMANIASIS, CUTANEOUS) in the New World. The sandfly, Lutzomyia, appears to be the vector.

Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.

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