Dendritic Cell Vaccine Personalized DCVax - Biotech, Pharma and Life Science Channel
PubMed Articles
Accumulating evidence has shown that microRNAs are involved in multiple processes in cancer development and progression. Recently, miR-22 has been identified as a tumor-suppressing microRNA in many hu...
Recently, novel molecular targeted agents markedly changed the treatment of renal cell carcinoma (RCC), with promising results. However, there is little understanding of how these agents affect immune...
Hypermethylation and prognostic implication of Syk gene in human colorectal cancer.
The study was aimed to investigate the relationship between hypermethylation of Syk gene and clinicopathological characteristics and long-term outcomes in colorectal cancer. The effect of Syk on cell...
The human papillomavirus (HPV) vaccine helps to prevent cervical cancer. However, research indicates that public acceptance of the vaccine is suboptimal. Our aims were to evaluate the willingness of U...
PTPN4 negatively regulates CrkI in human cell lines.
PTPN4 is a widely expressed non-receptor protein tyrosine phosphatase. Although its overexpression inhibits cell growth, the proteins with which it interacts to regulate cell growth are unknown. In th...
A three-component homogeneous catalyst system has been prepared with an Ir(III) complex as the photosensitizer, artificial hydrogenases bearing a diiron core and dendritic frameworks as the proton red...
Nonylphenol (NP), a representative endocrine disruptor, interferes with reproductive function in aquatic organisms and animals. Although many previous studies have focused on apoptotic cell death by N...
β-Arrestins as Potential Therapeutic Targets for Alzheimer's Disease.
β-arrestins represent a small family of G protein-coupled receptors (GPCRs) regulators, which provide modulating effects by facilitating desensitization and internalization of GPCRs as well as initia...
Lactobacillus surface layer proteins: structure, function and applications.
Bacterial surface (S) layers are the outermost proteinaceous cell envelope structures found on members of nearly all taxonomic groups of bacteria and Archaea. They are composed of numerous identical s...
Recent clinical observations and experimental studies of our group indicate that macrophage migration inhibitory factor (MIF) may contribute to tumor progression in head and neck squamous cell carcino...
News Articles
Innovative X-ray method advances new treatments for genetic diseases
An international team of scientists using a new X-ray method recorded the internal structure and cell movement inside a living frog embryo in greater detail than ever before.
Transcranial random noise stimulation allows the brain to work more efficiently, say researchers
In the future, if you want to improve your ability to manipulate numbers in your head, you might just plug yourself in. So say researchers who report in the Cell Press journal Current Biology on May 1...
Research findings could lead to new therapies for stroke and other brain diseases
Scientists investigating the interaction of a group of proteins in the brain responsible for protecting nerve cells from damage have identified a new target that could increase cell survival.
Thioridazine works by weakening staphylococcal cell wall, new study reveals
In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resis...
VACCINES Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics
Natural killer cells: Adaptive control of NK cells
Regulatory T cells maintain NK cell homeostasis through the regulation of interleukin-2 availability.
The plasticity and stability of regulatory T cells
In this Viewpoint article, several experts share their thoughts on the plasticity and stability of regulatory T cells, discussing the recent advances in our understanding of the transcriptional and ep...
Scottish Government advises healthcare workers to get MMR jab
Healthcare workers in Scotland are being urged to get vaccinated against measles in light of the continuing increased risk of infection across the country. The Scottish Government has written to...
Aberrant expression of CCR4 in diffuse large B-cell lymphoma, not otherwise specified
Events
Cancer Vaccines will provide attendees with a complete view of the cancer immunotherapy field. Focusing on the discovery of new vaccines, developments in target identification
Select Biosciences' 4th annual Single Cell Analysis Summit 2013 will build on the overwhelming success of the previous Single Cell events.
SELECTBIO CellTech2014 will feature an integrated program of tracks designed to fully describe the latest trends in analysis of cells, cell-based assays, and high-content phenotypic assays.
World Vaccine Congress Europe 2013
Where global vaccine stakeholders meet to do business
Clinical Trials Asia Summit is a platform for key stake holders to engage and critically analyze the road map for further growth towards establishing sustainable leadership of India in global Clinical...
Cell Culture World Congress USA
North America’s commercial cell culture event
Advancing cord blood banking & therapeutics
Stem Cells & Regenerative Medicine Congress
North America’s commercial stem cells event
World Stem Cells & Regenerative Medicine Congress 2013
Europe's largest stem cells and regenerative medicine industry conference
Stem Cells & Cell Therapy Summit
Select Biosciences' Stem Cells & Cell Therapy Summit is focused on providing an up-to-date expansive view of the current marketplace
Companies
Cancer Genetics, Inc. (CGI) is an emerging leader in the field of personalized medicine, offering products and services that enable cancer diagnostics as well as treatments that are tailored to the...
Foundation Medicine is dedicated to the development of comprehensive tests that will help physicians personalize cancer treatment for their patients. Foundation Medicineâs la...
Eutropics Pharmaceuticals Inc.
Eutropics is addressing the need for improving the treatment of aggressive forms of leukemia, myeloma, lymphoma, and other cancers. The company is developing a novel diagnostic te...
Health Discovery Corporation is a molecular diagnostics company that uses advanced mathematical techniques to analyze large amounts of data to uncover patterns that might otherwis...
Auxogyn is a privately held medical technology company focused on advancing women's reproductive health by applying its novel scientific and clinical knowledge of early human developmental biology to...
OncoMed Pharmaceuticals is a clinical-stage company that discovers and develops novel therapeutics targeting cancer stem cells, the cells believed to be capable of driving tumor growth, recurrence and...
Pepperdine University Graziadio School of Business
Founded on the core values of integrity, stewardship, courage, and compassion, Pepperdine University's Graziadio School of Business and Management has been developing values-centered leaders for conte...
LDM Group is comprised of seasoned leaders with proven track records in consumer based communication and measurement. Our physician based patient messaging system (ScriptGuide®...
GL Rapha have been developing various ranges of pharmaceutical technologies specially focusing on Bio-pharmaceuticals such as recombinant proteins, synthetic peptides, and DDS bio similar based on t...
ConnectedHealth is based in Chicago, Illinois, and is a provider of a new health insurance exchange decision-support platform for health insurers, employers, and consumers....
Clinical Trials
Cell Lines From High-Risk Breast Tissue
Background: - Many risk factors for breast cancer have been identified, including family history, endocrine background, changes in breast tissue, cancer in one breast, radiation...
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with periphe...
RATIONALE: Vaccines made from a person's white blood cells may help the body build an effective immune response. PURPOSE: This phase I trial is studying the side effects of vaccine therap...
Imiquimod Cream in Treating Patients With Basal Cell Skin Cancer
RATIONALE: Biological therapies, such as imiquimod cream, work in different ways to stimulate the immune system and stop tumor cells from growing. PURPOSE: This randomized phase I trial i...
Stem Cell Collection With Ofatumumab
The goal of this clinical research study is to learn if it is possible to collect stem cells after ofatumumab and chemotherapy treatment. This study will also evaluate side-effects, number...
Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy
Background: - Drugs given to treat cancer (chemotherapy) can weaken the human immune system. But it can also become weaker because of aging. Interleukin (IL)-7, a molecule produced natura...
A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)
The main purpose of the study is to evaluate the efficacy and safety of the study drug known as prasugrel for the reduction of Vaso-Occlusive Crisis events in pediatric participants with s...
This randomized phase II trial is studying how well giving tacrolimus and mycophenolate mofetil (MMF) together with or without sirolimus works in preventing acute graft-versus-host disease...
Study of OSI-774 (Tarceva) in Previously Untreated Elderly Lung Cancer Patients
The primary purpose of this study is to determine whether the drug OSI-774 is less toxic and potentially as good as or better than standard chemotherapy drugs, when given to subjects with...
Vemurafenib, Cetuximab, and Irinotecan in Advanced Solid Cancers
The goal of this clinical research study is to find the highest tolerable dose of vemurafenib that can be given in combination with cetuximab and irinotecan to patients with advanced cance...
Videos
bob-extra-ro1Mbps_Strea001.mov
6-year brain tumor survivor Bob Gibbs discusses Northwest Biothereputics (NWBO.OB) personalized cancer vaccine under development - DCVax-Brain.
Medical and Biotech [MESH] Definitions
Chromosomes, Plant
Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of PLANTS.
Mass Vaccination
Administration of a vaccine to large populations in order to elicit IMMUNITY.
Spectral Karyotyping
The simultaneous identification of all chromosomes from a cell by fluorescence in situ hybridization (IN SITU HYBRIDIZATION, FLUORESCENCE) with chromosome-specific florescent probes that are discerned by their different emission spectra.
Chromosomes, Mammalian
Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of MAMMALS.
Stem Cell Transplantation
The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.
