Diabetes - Biotech, Pharma and Life Science Channel
2.8 million people in the UK have been diagnosed with diabetes in the UK and a further 850,000 people are undiagnosed.
Diabetes is characterized by high blood glucose levels, resulting from a problem with Insulin (which is the natural compound that regulates glucose storage). In Type 1 diabetes, no insulin is produced at all because the insulin-producing cells in the pancreas have been destroyed. This type of diabetes is always treated with insulin injections.
In Type 2, Insulin is produced, but there is either insufficient amounts or it does not work effectively. This type of diabetes is treated with lifestyle changes, following a healthy balanced diet, increasing physical activity, and losing weight if needed. Some people may need medications and/or insulin injections to achieve normal blood glucose levels. Risk factors for Type 2 Diabetes include family history, obesity, hypertension, previous CVD, PCO and severe mental health problems.
It is very important to treat diabetes, and maintain scientific research into this disease because of the complications that Diabetes can cause; cardiovascular disease, retinopathy, neuropathy, nephropathy, hypoglycaemia, diabetic ketoacidosis or hyperosmolar hyperglycaemic state (HHS).
Source; Adapted from Diabetes UK
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PubMed Articles
Facebook as a platform for health information and communication: a case study of a diabetes group.
As one of the largest social networking sites in the world, Facebook holds a great potential for promoting health. In this exploratory study, we analyzed 1352 messages posted to an active Facebook dia...
Enhancement of wound closure in diabetic mice by ex vivo expanded cord blood CD34(+) cells.
Diabetes can impair wound closure, which can give rise to major clinical problems. Most treatments for wound repair in diabetes remain ineffective. This study aimed to investigate the influence on wou...
Oxidative stress has been suggested as a potential contributor to the development of diabetic complications. In this study, we investigated the protective effect of a strong antioxidant copper complex...
BACKGROUND: The purpose of the present study was to determine the prevalence of diabetes and its effect on surgical outcomes in patients undergoing emergent, in-patient cholecystectomy for acute chole...
Patients with both chronic kidney disease (CKD) and diabetes mellitus (DM) are at increased risk for thrombotic events compared to those with one abnormality alone. Whether this can be attributed to c...
AIMS/HYPOTHESIS: This study aimed to systematically review what has been reported on the incidence and prevalence of type 2 diabetes in children and adolescents, to scrutinise the methodological issue...
Role of plasma kallikrein in diabetes and metabolism.
Plasma kallikrein (PK) is a serine protease generated from plasma prekallikrein, an abundant circulating zymogen expressed by the Klkb1 gene. The physiological actions of PK have been primarily attrib...
Aim: We assessed the relationship between the level of high-sensitivity C-reactive protein (hsCRP) and cardiovascular risk factors in Korean adults.Methods: We reviewed 1,561 patients with cardiovascu...
Current and future therapies for hepatitis C virus infection.
Enhancing diabetes care by adding a pharmacist to the primary care team.
PURPOSE: The impact of pharmacist interventions on short-term clinical markers and long-term cardiovascular risk in patients with type 2 diabetes is investigated. METHODS: Selected health outcomes wer...
News Articles
Why MannKind's Afrezza Will Succeed Where Pfizer Failed
ByCory Renauer:According to the American Diabetes Association over 25 million people in the US alone have diabetes and the numbers keep on growing. Although insulin injections have come a long way, po...
Statins May Reduce Exercise Benefits For Obese Adults
Statins, the most widely prescribed drugs worldwide, are often suggested to lower cholesterol and prevent heart disease in individuals with obesity, diabetes and metabolic syndrome, which is a combina...
Newer class of diabetes medications may also improve cardiovascular health, researchers report
A newer class of medications used to control blood sugar levels in type 2 diabetics may also improve cardiovascular health, researchers from The Ohio State University Wexner Medical Center reported in...
An evaluation of the first year of a major integrated care pilot—seen as a test bed for national government policy—has found little change in emergency admissions and in the wider use of health an...
Public offering nets $18.8mm for [Cyclacel]
[Cyclacel Pharmaceuticals Inc.] (mainly cancer therapies; also has projects for kidney disease, diabetes, and HIV/AIDS) netted $18.8mm through public offering of 6.67mm common shares at $3 each. Proce...
G-BA rebuffs Pixuvri, Trajenta for second indication
Germany's Federal Joint Committee (G-BA) issued a final benefit assessment rebuffing diabetes drug Trajenta linagliptin from Boehringer Ingelheim GmbH (Ingelheim, Germany) as add-on therapy to insulin...
Researchers Face Off Over Incretin Risk
(MedPage Today) -- As concerns escalate over the potential risks of glucagon-like peptide-1 (GLP-1)-based therapies, a diabetes journal hosted a point-counterpoint debate between the researchers who h...
Injectable nanoparticles developed at MIT may someday eliminate the need for patients with Type 1 diabetes to constantly monitor their blood-sugar levels and inject themselves with insulin. (Phys.org)
The Committee adopted by consensus a positive opinion for an initial marketing authorisation application for ProZinc (insulin human) from Boehringer Ingelheim Vetmedica GmbH, for the treatment of di...
Exercise prevents fructose-induced hypertriglyceridemia
(HealthDay)—Moderate aerobic exercise prevents fructose-induced hypertriglyceridemia in healthy males, according to a study published online May 14 in Diabetes.
Events
Diabetes: Secondary Complications, Regulation and Innovation Conference
SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.
Companies
Diabetes Care Club, a Simplex brand, has grown to become the third largest mail-order supplier of diabetic testing supplies for seniors. The company provides home delivery...
Eli Lilly and Company is a leading, innovation-driven corporation committed to developing a growing portfolio of best-in-class and first-in-class pharmaceutical products that help people live longer...
TheAmerican Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Headquartered in Basel, Switzerland, Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Roche is the worldâs largest...
GlycoMark Inc. is a joint venture by Toyota Tsusho America Inc. (New York, N.Y.), Nippon Kayaku (Tokyo, Japan), and the BioMarker Group (N.C.). Located in New York, N.Y., a...
America Stem Cell is a privately held biotechnology company based in San Antonio, TX, with offices in San Diego, CA, and is dedicated to the development and commercialization of s...
IDEAL LIFE, the industry leader in remote health management solutions, has created an innovative platform that addresses many of todayâs most challenging and costly healthcar...
Based in Atlanta, GA, Team Type 1 began as a grassroots initiative to motivate people to take control of their diabetes using cycling as a platform. It grew to become a world-clas...
Based in Houston, Texas, ApoCell (www.apocell.com) is a privately-held specialty clinical research company. Founded in 2004, the firm is a leader in molecular biomarker detection...
LW Robbins (www.lwra.com) is a full service direct response fundraising agency devoted to helping nonprofit organizations acquire and cultivate loyal donors, and raise more...
Clinical Trials
Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes
This Phase 3, open-label, multicenter study is designed to compare the effects of exenatide and insulin glargine (Lantus® injection) on beta-cell function in patients with type 2 diabetes...
A Type 2 Diabetes Study of the Longer-Term Glycemic Effect of AVANDAMET vs. Metformin
This study will evaluate the longer-term glycemic effect of two medicines approved for initial treatment of type 2 diabetes. The study consists of a 2 week screening period (2 study visits...
Exercise and Metformin in Colorectal and Breast Cancer Survivors
Metformin is a medication that is commonly used in the treatment of diabetes. Recently small studies in cancer patients without diabetes suggest that metformin may benefit in lowering ins...
A Study Comparing the Effects and Safety of Dulaglutide With Glimepiride in Type 2 Diabetes Mellitus
The purpose of this study is to examine if once-weekly dulaglutide is efficient and safe compared to glimepiride in participants with type 2 diabetes who have inadequate glycemic control w...
Internet Diabetes Self-Management Workshop
The purpose of this study is to determine of the effectiveness of an Internet based Diabetes Self-Management workshop for people with type II diabetes. Half of the people who complete the...
A Study in Patients With Diabetic Kidney Disease
The purpose of this study is to determine if LY2382770 is safe and effective at protecting kidney function in patients with kidney disease due to diabetes.
The purpose of this study is to evaluate the use of SMBG and CGM for clinical decisions related to the management of type 2 diabetes. The secondary objective is to determine the benefit o...
Effects of Acute Intake of Caffeinated Beverages in Type 1 Diabetes
The aim of this pilot study is to determine the impact of caffeine-enhanced energy drinks on blood glucose excursion on heart rate, blood pressure, cardiac output and cognitive performance...
Effect of a Decision Aid About Statin Use in Patients With Type 2 Diabetes Mellitus
Background- Statins are a safe and effective therapy to reduce cardiovascular risk in patients with type 2 diabetes; however some patients are not prescribed statins, others do not take it...
GALLANT 6 Tesaglitazar vs. Pioglitazone
This is a 24-week randomized, double-blind, multi-center, active-controlled (pioglitazone) study of tesaglitazar (0.5 mg and 1 mg) in patients with type 2 diabetes, not adequately controll...
Videos
Animation about diabetes and the body.
There are two main types of diabetes, known as Type 1 and Type 2. Both types of diabetes are lifelong health conditions. There are 2.9 million people diagnos...
Medical and Biotech [MESH] Definitions
Candida Tropicalis
A species of MITOSPORIC FUNGI that is a major cause of SEPTICEMIA and disseminated CANDIDIASIS, especially in patients with LYMPHOMA; LEUKEMIA; and DIABETES MELLITUS. It is also found as part of the normal human mucocutaneous flora.
Ppar Gamma
A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR ALPHA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES. It is a target of THIAZOLIDINEDIONES for control of DIABETES MELLITUS.
Diabetes Complications
Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.
Pancreatitis, Chronic
INFLAMMATION of the PANCREAS that is characterized by recurring or persistent ABDOMINAL PAIN with or without STEATORRHEA or DIABETES MELLITUS. It is characterized by the irregular destruction of the pancreatic parenchyma which may be focal, segmental, or diffuse.
Aquaporin 2
Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA MEMBRANE is regulated by VASOPRESSIN, and MUTATIONS in AQP2 have been implicated in a variety of kidney disorders including DIABETES INSIPIDUS.
