Dialysis - News, Views, Blogs - Biotech, Pharma and Life Science Channel
In medicine, dialysis is a process for removing waste and excess water from the blood, and is primarily used to provide an artificial replacement for lost kidney function in people with renal failure. Dialysis may be used for those with an acute disturbance in kidney function (acute kidney injury, previously acute renal failure) or for those with progressive but chronically worsening kidney function–a state known as chronic kidney disease stage 5 (previously chronic renal failure or end-stage kidney disease).
The kidneys have important roles in maintaining health. When healthy, the kidneys maintain the body's internal equilibrium of water and minerals (sodium, potassium, chloride, calcium, phosphorus, magnesium, sulfate). Those acidic metabolism end products that the body cannot get rid of via respiration are also excreted through the kidneys. The kidneys also function as a part of the endocrine system producing erythropoietin and calcitriol. Erythropoietin is involved in the production of red blood cells and calcitriol plays a role in bone formation. Dialysis is an imperfect treatment to replace kidney function because it does not correct the endocrine functions of the kidney. Dialysis treatments replace some of these functions through diffusion.
Source: Wikipedia
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News Articles
Nephros Announces Completion of Rights Offering
RIVER EDGE, N.J., May 23, 2013 /PRNewswire/ -- Nephros, Inc. (OTC Bulletin Board:NEPH), a commercial stage medical device company that develops and sells high performance liquid purification ultrafilt...
WASHINGTON, May 22, 2013 /PRNewswire-USNewswire/ -- Bi-partisan members of the Senate Finance Committee and Chairman of the Budget Committee urged Centers for Medicare and Medicaid Services (CMS)...
Emergency Response Plans Ensure That Dialysis Patients Can Get Life-Sustaining Treatments When Disaster Strikes With construction crews still repairing damage from last year...
NxStage Announces New Agreements with DaVita
LAWRENCE, Mass., May 21, 2013 /PRNewswire/ -- NxStage Medical, Inc. (Nasdaq: NXTM), a leading manufacturer of innovative dialysis products, today announced that it has entered into new agreements...
U.S. Renal Care pays $7.3 million to settle billing fraud case brought by nurse-whistleblower
BALTIMORE, May 21, 2013 /PRNewswire/ -- U.S. Renal Care has agreed to pay $7.3 million to the federal government to settle a whistleblower lawsuit brought by a nurse that alleged a company U.S. R...
ALung to Pursue SFDA Approval of Hemolung RAS in China
Agreement Signed with Curative Medical to Initiate Clinical Trial ALung Technologies, Inc., a leading developer of innovative respiratory assist devices, today announced that...
ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials
ISTANBUL, May 21, 2013 /PRNewswire/ -- The congress of the ERA-EDTA (European Renal Association - European Dialysis and Transplant Association) is the biggest congress in Europe on nephrol...
Cantel Medical To Present At The Deutsche Bank 38th Annual Health Care Conference
LITTLE FALLS, N.J., May 20, 2013 /PRNewswire/ -- CANTEL MEDICAL CORP. (NYSE: CMN) announced today that Andrew A. Krakauer, President & CEO, will be presenting at the Deutsche Bank 38th Annual...
Fresenius Medical Care Wins Multiple National Awards for Outstanding Patient Case Management
Case in Point Magazine’s 2013 Awards Recognize Programs and Individuals Making the U.S. Health Care System Safer, More Productive and Cost Effective Fresenius...
NORTH CHICAGO, Ill., May 20, 2013 /PRNewswire/ -- AbbVie (NYSE: ABBV) announced today the initiation of a Phase 3 clinical study called SONAR (Study Of Diabetic Nephropathy with Atrasentan) to as...
Events
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Companies
Renal Ventures Management, LLC
Renal Ventures Management, LLC is a leading provider of dialysis services. The company partners with top physicians to provide patients with knowledgeable, compassionate and quali...
American Renal Associates LLC (âARAâ) is the operating subsidiary of American Renal Holdings, Inc. and is a leading owner and provider of outpatient kidney dialysis cent...
Established in 1982, Spectra Laboratories, Inc. is the leading provider of renal-specific laboratory testing services in the United States. The companyâs state-of-the-art ana...
DaVita Inc., a Fortune 500® company, is a leading provider of kidney care in the United States, delivering dialysis services to patients with chronic kidney failure and end sta...
DaVita HealthCare Partners, a Fortune 500® company, is the parent company of DaVita and HealthCare Partners. DaVita is a leading provider of kidney care in the United States, d...
Trevi Therapeutics, Inc. is a drug development company founded in 2011 focused on developing T111 for the severe chronic itching condition known as pruritus. Pruritus is ma...
AngioDynamics, Inc. is a leading provider of innovative medical devices used by interventional radiologists, surgeons and other physicians for the minimally-invasive treatment of...
DaVita Inc., a Fortune 500® company, is a leading provider of kidney care in the United States, delivering dialysis services and education to patients with chronic kidney failu...
American CareSource Holdings, Inc.
American CareSource Holdings, the first national, publicly traded ancillary care network services company, offers a comprehensive national network of over 4,100 ancillary service...
Fresenius Medical Care North America
Fresenius Medical Care North America is a subsidiary of Fresenius Medical Care AG & Co. KGaA, the world's largest integrated provider of products and services for individuals unde...
Clinical Trials
Iron Sucrose in Stage 3/4 Kidney Disease
One of the complications of late stage kidney disease is the development of a low red blood cell count (anaemia/low haemoglobin concentration). The Australian Commonwealth government limit...
Pilot Study of Mycophenolate Mofetil in Congenital Uropathies
Congenital or hereditary structural anomalies of the genitourinary tract account for approximately half of all cases of end stage renal disease in the pediatric population. Despite optimal...
N-Acetylcysteine for Preventing Renal Injury After Cardiac Surgery
Cardiac surgery improves the survival and quality of life of people with heart disease. Nonetheless, several complications continue to adversely affect outcomes following cardiac surgery....
This trial is conducted in Europe. Objective(s): To evaluate the effect of human growth hormone on infants aged 1 to 2 years with chronic renal insufficiency (CRI) and growth retardation...
Malnutrition and Inflammation in Dialysis Patients in Taiwan
According to the reports of the United States Renal Data System (USRDS), there is a 25% annual mortality rate with nearly 50% of all reported maintenance hemodialysis (HD) patient deaths a...
The Factors Predicting Change of Peritoneal Transport Characters in Peritoneal Dialysate
Peritoneal fibrosis (PF) is one of the most serious complications after long-term continuous ambulatory peritoneal dialysis (CAPD). Human peritoneal fibroblast (HPFB) and extracellular mat...
Patients affected by end-stage renal disease (ESRD) are subjected to enhanced oxidative stress, as a result of reduced anti-oxidant systems and increased pro-oxidant activity. Besides, ins...
Effects of Cognitive-Behavioral Therapy on Sleep Disturbance in Peritoneal Dialysis Patients
Sleep disturbance is prevalent in chronic dialysis patients and there is a negative correlation between the quality of life and overall survival and sleep disturbance in them. Cognitive-be...
Enzyme Replacement Therapy in Fabry Disease
Fabry disease is an X-linked rare metabolic disease, caused by a deficient activity of the hydrolase α-Galactosidase A, and characterized by a progressive and systematic deposition of gly...
Haemodialysis Salt Reduction Study
High blood pressure (hypertension) affects up to 80% of all patients receiving haemodialysis for chronic kidney disease (CKD). High blood pressure is a major cause cardiovascular disease...
PubMed Articles
Sirolimus- vs. paclitaxel-eluting stent to coronary intervention in dialysis patients.
Patients on maintenance hemodialysis (HD) are at high risk for restenosis after percutaneous coronary intervention (PCI) even if treated with a sirolimus-eluting stent (SES). The aim of this study was...
Beta-blocker prevents sudden cardiac death in patients with hemodialysis.
Beta blockers were shown to prevent SCD in cardiomyopathy or coronary artery disease patients. Dialysis patients show elevated mortality rates, predominantly due to cardiovascular disease. SCD is now...
Nutritional predictors of early mortality in incident hemodialysis patients.
PURPOSE: Low serum albumin concentration and low dietary protein intake are associated with protein-energy wasting (PEW) and higher mortality in maintenance hemodialysis patients. The role of these nu...
To elucidate the interspecies variation of susceptibility to microcystins (MCs), fresh plasma and purified albumin from six kinds of mammals and fish were used in toxins-substances binding test. Prote...
Sexual dysfunction predicts depression among women on hemodialysis.
PURPOSE: Depression is common in patients on hemodialysis (HD), and its treatment fails in many cases. Among women on HD, sexual dysfunction (SD) can be an underestimated cause of depression and an im...
Oxadiazole-isopropylamides as Potent and Noncovalent Proteasome Inhibitors.
Screening of the 50 000 ChemBridge compound library led to the identification of the oxadiazole-isopropylamide 1 (PI-1833) which inhibited chymotrypsin-like (CT-L) activity (IC50 = 0.60 μM) with li...
PURPOSE: Patient-reported outcomes are important endpoints to evaluate new models of renal delivery. This is the first study to compare Quality of Life (QOL) and emotional adjustment outcomes between...
Peritoneal dialysis-current status and future challenges.
Peritoneal dialysis is now a well established, mature treatment modality for advanced chronic kidney disease. The medium term (at least 5 year) survival of patients on peritoneal dialysis is currently...
Dialysis: Decrease in mortality among US children starting dialysis.
Regenerative medicine for the kidney: stem cell prospects and challenges.
The kidney has key roles in maintaining human health. There is an escalating medical crisis in nephrology as growing numbers of patients suffer from kidney diseases that culminate in organ failure. Wh...
Videos
Dialysis
If you like this animation, LIKE us on Facebook: http://www.nucleusinc.com/facebook http://www.nucleusinc.com/medical-animation Dialysis. This 3D medical ani...
Medical and Biotech [MESH] Definitions
Peritoneal Fibrosis
Disorder characterized by a wide range of structural changes in PERITONEUM, resulting from fibrogenic or inflammatory processes. Peritoneal fibrosis is a common complication in patients receiving PERITONEAL DIALYSIS and contributes to its gradual decrease in efficiency.
Ultrafiltration
The separation of particles from a suspension by passage through a filter with very fine pores. In ultrafiltration the separation is accomplished by convective transport; in DIALYSIS separation relies instead upon differential diffusion. Ultrafiltration occurs naturally and is a laboratory procedure. Artificial ultrafiltration of the blood is referred to as HEMOFILTRATION or HEMODIAFILTRATION (if combined with HEMODIALYSIS).
Hemodialysis Solutions
Solutions prepared for hemodialysis. The composition of the pre-dialysis solution may be varied in order to determine the effect of solvated metabolites on anoxia, malnutrition, acid-base balance, etc. Of principal interest are the effect of the choice of buffers (e.g., acetate or carbonate), the addition of cations (Na+, K+, Ca2+), and addition of carbohydrates (glucose).
Dialysis Solutions
Solutions prepared for exchange across a semipermeable membrane of solutes below a molecular size determined by the cutoff threshold of the membrane material.
Sorption Detoxification
Elimination of toxic or biologically active substances from body fluids by interaction with a sorbent medium. The types of media include absorbents, adsorbents, ion-exchange materials, and complexing agents. Detoxification can be extracorporeal (hemodialysis, hemofiltration, hemoperfusion, plasmapheresis), or occur inside the body (enterosorption, peritoneal dialysis).
