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Diseases caused by Haemophilus sp - Biotech, Pharma and Life Science Channel

11:05 EDT 19th June 2013 | BioPortfolio

PubMed Articles [ 7384 Associated PubMed Articles listed on BioPortfolio]

Pleiotropic Potential of Dehydroxymethylepoxyquinomicin for NF-κB Suppression via Reactive Oxygen Species and Unfolded Protein Response.

Dehydroxymethylepoxyquinomicin (DHMEQ) is a low-m.w. compound that strongly inhibits NF-κB. Previous reports showed that DHMEQ directly binds to specific cysteine residues of NF-κB subunits and ther...

SOCS3 Regulates BAFF in Human Enterocytes under Ribosomal Stress.

Although the activation of B cells in the gastrointestinal tract is of great importance in the context of immunity to pathogens and mucosal inflammatory diseases, little is known about the mechanisms...

Immunization with Biodegradable Nanoparticles Efficiently Induces Cellular Immunity and Protects against Influenza Virus Infection.

The ability of vaccines to induce T cell responses is crucial for preventing diseases caused by viruses or bacteria. Nanoparticles (NPs) are considered an efficient tool for inducing potent immune res...

Intestinal organoids as tissue surrogates for toxicological and pharmacological studies.

Recently developed cell culture protocols have allowed for the derivation of multi-cellular structures dubbed intestinal "organoids" from embryonic stem cells (ESCs), induced pluripotent stem cells (I...

Assessing the damage caused by Deepwater Horizon: Not just another Exxon Valdez.

In light of the high stakes of the Deepwater Horizon civil trial and the important precedent-setting role that the case will have on the assessment of future marine disasters, the methodologies underp...

Benzoapyrene affects Jurkat T cells in the activated state via the antioxidant response element dependent Nrf2 pathway leading to decreased IL-2 secretion and redirecting glutamine metabolism.

There is a clear evidence that environmental pollutants, such as benzo[a]pyrene (B[a]P), can have detrimental effects on the immune system, whereas the underlying mechanisms still remain elusive. Jurk...

Resistance to bacterial infectious diseases in rainbow trout (Oncorhynchus mykiss).

Individually tagged rainbow trout representing 15 full-sibling families were sequentially challenged twice with Aeromonas salmonicida causing furunculosis: first as cohabitation and then as injected i...

Emergence of serogroup X meningococcal disease in Africa: Need for a vaccine.

Neisseria meningitidis is responsible for the seasonal burden and recurrent epidemics of meningitis in an area of sub-Saharan Africa known as the meningitis belt. Historically, the majority of the cas...

Managing the Underlying Cause of Cystic Fibrosis: A Future Role for Potentiators and Correctors.

Cystic fibrosis (CF), a severe genetic disease, is caused by mutations that alter the structure and function of CFTR, a plasma membrane channel permeable to chloride and bicarbonate. Defective anion t...

Lumbar facet joint injection: feasibility as an alternative method in high-risk patients.

OBJECTIVE: To evaluate the effectiveness of therapeutic facet joint steroid injections for symptoms caused by lumbar spinal stenosis in patients who are at risk of bleeding. METHODS: We analysed 134 p...

News Articles [ 6335 Associated News Articles listed on BioPortfolio]

Diagnosis and management of first trimester miscarriage

Summary pointsMiscarriage is the most common complication of pregnancy, affecting 12-24% of all pregnanciesMost early miscarriages are caused by chromosomal abnormalities, and the risk of miscarriage....

Tick-borne Disease Alliance Calls for Parents to Protect Children from Ticks at Summer Camp, Offers Simple Steps for Prevention

Five- to Fourteen-year olds at Highest Risk of Infection by Devastating Tick-Borne Diseases, including Lyme. New York, NY (PRWEB) June 19, 2013 This summer as thousands of children across the U.S. le...

Mirena Multidistrict Litigation Moves Forward: Now, AttorneyOne Can Provide Advice

According to court documents, the next case management conference for the Mirena IUD Multidistrict Litigation will take place on July 1. In light of this news, AttorneyOne, a recognized authority on l...

Lipidation states in certain proteins in the brain differ depending on genotype, cognitive diseases

The lipidation states (or modifications) in certain proteins in the brain that are related to the development of Alzheimer disease appear to differ depending on genotype and cognitive diseases, and le...

New research draws link between people's beliefs and obesity crisis

Whether a person believes obesity is caused by overeating or by a lack of exercise predicts his or her actual body mass, according to new research published in Psychological Science, a journal of the...

Dynavax Chief Scientific Officer Awarded Prestigious Immunology Prize

BERKELEY, CA -- (Marketwired) -- 06/19/13 -- Dynavax Technologies Corporation (NASDAQ: DVAX) announced today that the 2013 Novartis Prize for Basic Immunology has been awarded to Dr. Robert L. Coffma...

Preventing Vascular Calcification May Treat One Of The Main Symptoms Of Premature Aging Disease

HGPS is a rare genetic disease that affects one in every 4-8 million births. The disease is caused by a spontaneous mutation in one of the two copies (alleles) of the gene LMNA, which codes for lamin...

In A Mouse Model Of Polycystic Kidney Disease, Vitamin B3 Blocks Cyst Formation

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited systemic disorder caused by mutations in PKD1 or PKD2 that predominately affects the kidneys and is characterized by the formation...

Renal sympathetic denervation: applications in hypertension and beyond

Increased sympathetic activity is associated with a number of diseases, including resistant hypertension. Renal denervation is becoming increasingly prevalent throughout Europe as a treatment for this...

More Organ-Donor Testing is Advised

The federal government recommended expanding the number of diseases that organ donors should be screened for, adding hepatitis B and hepatitis C to the list.

Events [ 4 Associated Events listed on BioPortfolio]

Orphan Drugs & Rare Diseases

Recent years have seen huge growth in orphan drug development, but also a time of increased pressure as many leading blockbuster drugs soon come off patent.

Infectious Diseases World Summit 2013

3 Tracks: 10th Anti-Infectives Partnering and Deal-Making 11th Vaccines Research & Development: All Things Considered 2nd Influenza Research & Development

Molecular Medicine Congress

Welcome to Molecular Medicine Congress and exhibition.

CNS Disease World Summit

The CNS Diseases World Summit 2013 brings together the leading experts across the industry and academia to discuss the latest research and developments in the CNS field.

Companies [ 263 Associated Companies listed on BioPortfolio]

Resverlogix Corporation

Resverlogix Corp. (TSX: RVX) is a clinical stage cardiovascular company with an epigenetic platform technology that modulates protein production. Resverlogix is developing RVX-208, a first-in-class...

Bristol-Myers Squibb Company and Simcere Pharmaceutical Group

Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases....

NanoLogix, Inc.

NanoLogix is a biotechnology company focused primarily on medical diagnostics. Its products offer accelerated detection and identification of microorganisms present in infectious and non-infectious hu...

Kadimastem Ltd.

Kadimastem is a biotechnology company focusing on the development and industrial commercialization of products based on human pluripotent stem cells. Kadimastem’s technology...

The Moran Eye Center

The Moran Eye Center is the largest eye care and vision research center in the Intermountain West and is part of the University of Utah Hospitals and Clinics. With collaborators f...

NeuroMetrix, Inc.

NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...

Bioness Inc.

Bioness offers innovative Neuromodulation products designed to help certain individuals with central nervous system disorders and diseases such as Stroke, Multiple Sclerosis, Trau...

Ocular Therapeutix, Inc.

Ocular Therapeutix, Inc. is a privately held company based in Bedford, MA, focused on the development and commercialization of ophthalmic therapeutic products using its proprietar...

MediGene AG

Medigene is a publicly listed (Frankfurt: MDG, prime standard) biotechnology company headquartered in Martinsried/Munich, Germany. Medigene is focused on the research and development of innovative d...

Astellas Pharma Inc.

Astellas Pharma Inc., located in Tokyo, Japan, is a pharmaceutical company dedicated to improving the health of people around the world through the provision of innovative and reliable pharmaceuticals...

Clinical Trials [ 2034 Associated Clinical Trials listed on BioPortfolio]

Fat Biology, Sleep Disorders, and Cardiovascular Disease

Endothelial dysfunction, or abnormal functioning of the lining of blood vessels, appears to be a key process in the development of cardiovascular disease. Endothelial dysfunction appears t...

Pilot Trial to Assess Effect of CNI Conversion of Efalizumab on T Reg Cells

The purpose of this pilot trial is to determine whether a conversion from calcineurin inhibitors (CNI) and mycophenolate mofetil (MMF) to a regimen consisting of efalizumab and sirolimus i...

Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants

To determine whether or not inhaled nitric oxide (iNO) safely decreases the incidence of chronic lung disease (CLD) in premature infants.

Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion

This study will evaluate whether the drug mifepristone can improve the symptoms of Cushing's syndrome in people with ectopic adrenal corticotrophin hormone (ACTH) secretion. Cushing's synd...

Nephrotic Syndrome Study Network

Minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and Membranous nephropathy (MN), generate an enormous individual and societal financial burden, accounting for appr...

Pharmacokinetics, Efficacy, and Safety Study of RI-002 (IGIV) in Subjects With Primary Immunodeficiency Diseases (PIDD)

This is a Phase III, multicenter, open-label study of RI-002 administered as an intravenous infusion of RI-002 (IGIV) every 21 or 28 days in approximately 60 subjects with Primary Immunode...

Glutamine in Preventing Myalgia and/or Arthralgia in Patients Who Are Receiving Paclitaxel For Cancer

RATIONALE: Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Nutriti...

Primary Care Management/Action Plans for Advanced Chronic Diseases

Patients living with advanced chronic diseases (ACD), such as congestive heart failure (CHF) and chronic obstructive lung disease (COPD) present substantial care and economic challenges fo...

Double Bedtime Dosing During Immediate-Release Morphine Administration to Cancer Patients

This is a double -blind randomized crossover study to provide evidence for the expert advice based recommendation of the Expert Working Group of the European Association for Palliative Car...

Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

Problems of compatibility between a mother and her child are frequent. The most well-known case can be illustrated by the fetomaternal blood group incompatibility (rhesus factor) which can...

Videos

Substrains of Morgellons

Morgellons is CBL-001 Phoma Sp. (Pleospora) and there is other strains. A mad scientist fused a Cyanobacteria with a plant disease. Morgellons is also called...

Medical and Biotech [MESH] Definitions

Andrology

A scientific or medical discipline concerning the study of male reproductive biology, diseases of the male genital organs, and male infertility. Major areas of interest include ENDOCRINOLOGY; SPERMATOGENESIS; semen analysis; FERTILIZATION; CONTRACEPTION; and CRYOPRESERVATION.

Hyperuricemia

Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.

Insomnia, Fatal Familial

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

Reproductive Health Services

Health care services related to human REPRODUCTION and diseases of the reproductive system. Services are provided to both sexes and usually by physicians in the medical or the surgical specialities such as REPRODUCTIVE MEDICINE; ANDROLOGY; GYNECOLOGY; OBSTETRICS; and PERINATOLOGY.

Streptococcus Milleri Group

A subset of VIRIDANS STREPTOCOCCI, but the species in this group differ in their hemolytic pattern and diseases caused. These species are often beta-hemolytic and produce pyogenic infections.

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