Dysphagia - Biotech, Pharma and Life Science Channel
PubMed Articles
Swallowing and Respiratory Distress in Hospitalized Patients with Bronchiolitis.
The aim of this study was to evaluate the risk of airway and/or pulmonary food or saliva aspiration in infants with moderate respiratory distress who are hospitalized with respiratory syncytial virus...
Clinical relevance and prognostic value of radiographic findings in Zenker's diverticulum.
The aim of this study was to evaluate the clinical relevance and prognostic value of preoperative and postoperative oesophagography in patients with Zenker's diverticulum. The medical records of 155 p...
Early dysphagia complicating anterior cervical spine surgery: incidence and risk factors.
BACKGROUND: Dysphagia is a common complication of anterior cervical spine surgery, and most of them occurred in the early postoperative period. This study aimed to determine the incidence of early dys...
Age-related Differences in Tongue-Palate Pressures for Strength and Swallowing Tasks.
The tongue plays a key role in the generation of pressures for transporting liquids and foods through the mouth in swallowing. Recent studies suggest that there is an age-related decline in tongue str...
What is "Usual Care" in Dysphagia Rehabilitation: A Survey of USA Dysphagia Practice Patterns.
The scope of dysphagia rehabilitation has been expanding. Therapeutic approaches have begun to move away from the use of behavioral compensations and maneuvers only, toward a greater emphasis on resea...
Since the initial description in 2010 of anoctamin 5 deficiency as a cause of muscular dystrophy, a handful of papers have described this disease in cases of mixed populations. We report the first lar...
Dysphagia in amyotrophic lateral sclerosis: prevalence and clinical findings.
OBJECTIVES: To characterize swallowing deficits in amyotrophic lateral sclerosis (ALS); investigate the delay in dysphagia onset; estimate correlations between dysphagia severity and patients' functio...
Dissecting intramural hematoma of the esophagus (DIHE) is a rare condition in which intramural hemorrhage can lead to submucosal dissection of the esophageal wall. DIHE is generally considered a benig...
Patient self-management programs usually require participants to attend group sessions, which can be difficult for individuals with mobility issues. In addition, many programs are not disease specific...
BACKGROUND: There is a learning curve associated with laparoscopic antireflux surgery which has an impact on patient outcomes. It is unclear, however, whether this can be eliminated by supervision of...
News Articles
Phagenesis Expands Series B Financing to $17 million
Manchester, UK – 22 May 2013 − Phagenesis, the world’s leading company in the treatment of dysphagia, has expanded its Series B financing to $17m. In 2011, Phagenesis announced a...
New online resource provides practical guidance on caring for patients with dysphagia
Healthcare professionals caring for patients with dysphagia (swallowing difficulties) now have access to a new and comprehensive online resource called 'Medicines Optimisation in Patients with Dysphag...
New dysphagia and medicines resource now live
Healthcare professionals caring for patients with dysphagia (swallowing difficulties) now have access to a new and comprehensive online resource called 'Medicines Optimisation in Patients with Dysphag...
BioCrea and TU Dresden collaborate on human neuron screening platform
CNS drug discovery specialist BioCrea GmbH has established a collaboration with the Department of Neurology at Dresden University of Technology (TU Dresden) to discover new treatments for neurodegenea...
Keele University School of Pharmacy has launched a website providing guidance on medicines optimisation for patients with dysphagia. The website is aimed at healthcare professionals and includes l...
Study indentifies unmet medical need for treatment of patients with chronic pain and dysphagia
Collegium Pharmaceutical, Inc., a specialty pharmaceutical company focused on the development of innovative treatments for chronic pain, today announced the completion of a research study, conducted w...
Significant Unmet Medical Need for Treatment of Patients with Chronic Pain with Dysphagia (CPD)
CANTON, Mass., April 22, 2013 /PRNewswire/ -- Collegium Pharmaceutical, Inc., a specialty pharmaceutical company focused on the development of innovative treatments for chronic pain, today announ...
Merz North America (affiliate of Merz Pharma Group) congratulates Glenn Block, President and General Manager of Merz Pharma Canada, Ltd., who has been selected for induction into...
Small Sensor Placed On The Neck Records How A Patient With Suspected Dysphagia Swallows
Those suffering from swallowing difficulties, especially stroke patients, could be evaluated more efficiently and noninvasively thanks to research under way at the University of Pittsburgh and the Uni...
Dr. Oern Stuge Appointed Chairman of Phagenesis
Manchester, UK - 21 March 2013 - Phagenesis, the world's leading company in the treatment of dysphagia, has appointed Dr Oern Stuge, former senior executive at Medtronic and Abbott Laboratories,...
Events
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Companies
Phagenesis is developing the first clinically proven treatment for dysphagia, a debilitating and often lethal condition in which the patientâs ability to swallow is damaged....
Phagenesis is developing the first clinically proven treatment for dysphagia, a debilitating and often lethal condition in which the patientâs ability to swallow is damaged....
Swallow Solutions, LLC is dedicated to individuals suffering from swallowing disorders, generally known as dysphagia. We focus on two areas related to dysphagia â therapeutic...
Clinical Trials
A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab
Eosinophilic esophagitis (EE) is an increasingly recognized condition characterized by dysphagia, food impaction or other obstructive esophageal symptoms in children and young adults....
Comparison of Two Therapies for Upper Esophageal Sphincter (UES) Dysphagia
The aim of this research study is to determine the effectiveness of: 1) a traditional therapy regimen focusing on individual exercises for pharyngeal (throat) and laryngeal (voice box) mus...
This study will examine tongue strength and endurance, how the tongue applies pressure during swallowing, and how the chin muscles react during swallowing in healthy volunteers and in pati...
Introduction Patients with stroke may be silent aspirators or at risk for laryngeal penetration or aspiration because of abnormal oropharyngeal functioning and thus are at risk for aspirat...
Trial of Montelukast in Eosinophilic Esophagitis
Evaluate clinical effectiveness of oral montelukast compared to placebo on prevention of dysphagia and food impaction in patients with EE. Also evaluate tolerance and safety of oral monte...
Trial Comparing Side-to-Side Stapled and Hand-Sewn Esophagogastric Anastomosis in Neck
Carcinoma esophagus is a common cause of dysphagia. Once dysphagia occurs, a majority of the tumours are advanced. Most of them would require some form of treatments for control of dysphag...
Can Cytokines Predict the Severity of Acute Mucositis and the Need for Gastrostomy Tubes (PEG)?
Mucositis and xerostomia are the most common complications of head and neck (H&N) irradiation, and the combination of chemotherapy and radiation therapy is associated with a significantly...
Primary Objective: To determine if amifostine in combination with IMRT can mitigate the decrease in production of saliva by the submandibular and sublingual salivary glands in patients wi...
This study will compare an implant with the technique of sensory training to determine which method may improve the ability to swallow and reduce the risk of choking. Many people with a br...
RATIONALE: Placing a stent in the esophagus may lessen swallowing difficulties and improve quality of life in patients with malignant dysphagia caused by esophageal cancer or gastroesophag...
Videos
Swallow: A Documentary - Dysphagia
To help the cause please donate at http://www.nfosd.com We give our most sincere thanks to everyone in this film for sharing their stories and allowing us th...
Medical and Biotech [MESH] Definitions
Muscular Dystrophy, Oculopharyngeal
An autosomal dominant hereditary disease that presents in late in life and is characterized by DYSPHAGIA and progressive ptosis of the eyelids. Mutations in the gene for POLY(A)-BINDING PROTEIN II have been associated with oculopharyngeal muscular dystrophy.
Lingual Goiter
Pathological enlargement of the LINGUAL THYROID, ectopic thyroid tissue at the base of the TONGUE. It may cause upper AIRWAY OBSTRUCTION; DYSPHAGIA; or HYPOTHYROIDISM symptoms.
Lateral Medullary Syndrome
INFARCTION of the dorsolateral aspect of MEDULLA OBLONGATA in the BRAIN STEM. It is caused by occlusion of the VERTEBRAL ARTERY and/or the posterior inferior cerebellar artery. Clinical manifestations vary with the size of infarction, but may include loss of pain and temperature sensation in the ipsilateral face and contralateral body below the chin; ipsilateral HORNER SYNDROME; ipsilateral ATAXIA; DYSARTHRIA; VERTIGO; nausea, hiccup; dysphagia; and VOCAL CORD PARALYSIS. (From Adams et al., Principles of Neurology, 6th ed, p801)
Esophageal Spasm, Diffuse
A hypermotility disorder of the ESOPHAGUS that is characterized by spastic non-peristaltic responses to SWALLOWING; CHEST PAIN; and DYSPHAGIA.
Myelinolysis, Central Pontine
A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)
