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Eczema - Biotech, Pharma and Life Science Channel

11:28 EDT 22nd May 2013 | BioPortfolio

Eczema is a common itchy skin disease characterized by reddening and vesicle formation, which may lead to weeping and crusting. It is endogenous, or constitutional. There are five main types; atopic, seborrhoeic, discoid, gravitational or varicose.  (Oxford Medical Dictionary).

The most common form is atopic, affecting 5-15% of UK children by the age of seven. Often by teenage years, the eczema will have gone, but these adults may find they still have ‘sensitive’ skin.

Atopic eczema can flare up and then calm down for a time, but the skin tends to be dry and itchy even in-between flare ups, which can be caused by anything from soap and detergents to overheating and rough clothing. Research suggests that both genetic and environmental factors play a part. Eczema can be managed in the follow ways, as there is currently no cure; emollients (topical corticosteroids), creams, ointments and lotions

Source; Adapted from National Eczema Society (UK)

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News Articles [ 23 Associated News Articles listed on BioPortfolio]

PuraCap's Team EpiCeram® Joins Walk to Cure Eczema

SOUTH PLAINFIELD, N.J., May 22, 2013 /PRNewswire/ -- Team EpiCeram is proud to announce its support of the National Eczema Association's "Itching for a Cure" walk in New Jersey on June 8, 2013. W...

Peer-Reviewed Article Shows CLn® BodyWash an Effective Solution for Children with Eczema

Parents give product high marks Dallas-based TopMDTM Skin Care today announced results of its first peer-reviewed journal article testing the efficacy of their flagship...

Natural Relief for Eczema Available at Home from Jason International’s Oxygen Bath

Jason International’s MicroSilk® Hydrotherapy Bath Cleanses and Moisturizes Itchy Red Skin and Restores Nine-Year-Old’s Healthy, Clear Complexion As she read the w...

Onset Dermatologics Launches Patented Aurstat® Anti-Itch Hydrogel 225mL

Onset Dermatologics, a PreCision Dermatology Company and a leader in developing and commercializing novel, prescription products for improving skin health, today announced the ava...

With Seasonal Allergens Outside, It's Time To Build A Safe Haven Inside

JACKSONVILLE, Fla., March 7, 2013 /PRNewswire/ -- With the Spring thaw beginning to creep across the country, more than 35 million Americans will soon resume their annual allergy suffering brought on...

Sanofi and Regeneron Report Positive Proof-of-Concept Data for Dupilumab, an IL-4R alpha Antibody, in Atopic Dermatitis

PARIS and TARRYTOWN, N.Y., March 2, 2013 /PRNewswire/ -- Sanofi (EURONEXT: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that pooled data from two Phase 1b...

GlobalMed Telemedicine Camera Receives Canadian Certification

CSA Group, a nonprofit, membership-based association that tests and certifies products around the world, has certified the TotalExam™HD examination camera made by GlobalMed®, t...

Fast-food 'link' to child asthma and eczema

“Fast food and takeaways linked to surge in child asthma and allergies,” reports The Guardian. Along with many other papers, it reports on a study attempting to shed light on one of the enduring m...

Name That Itch: Allergic Skin Conditions

CHICAGO, Nov. 16, 2012 /PRNewswire/ -- Winter months can bring on the itch as cold weather and indoor heat dry out the skin. It's possible, suggests Chicago allergist, Brian Rotskoff, MD...

Upsher-Smith Joins The National Eczema Association To Take Action During Eczema Awareness Month

MAPLE GROVE, Minn., Sept. 24, 2012 /PRNewswire/ -- Upsher-Smith Laboratories, Inc. is proud to support the National Eczema Association (NEA) during Eczema Awareness Month in October...

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Companies [ 2 Associated Companies listed on BioPortfolio]

TopMD Skin Care

Founded by Texas physicians, Azam Anwar, M.D., and highly regarded dermatopathologist Clay Cockerell, M.D., TopMD Skin Care released its premier product, CLn® BodyWash, in the...

Jeffrey Klein M.D. Dermatology & Associates

Jeffrey Klein M.D. Dermatology & Associates serves patients throughout South Orange County, California with comprehensive cosmetic dermatology and general dermatology treatments,...

Clinical Trials [ 55 Associated Clinical Trials listed on BioPortfolio]

Quality of Life Study in Adults With Facial Eczema

This study is not being conducted in the US. The study consists of a 4 week double blind treatment period. All patients meeting the inclusion/exclusion criteria will enter the study at d...

Safety, Tolerability, and Immune Response of ACAM3000 Modified Vaccinia Ankara (MVA) Smallpox Vaccine in Adults

The purpose of this study is to gather information on the safety and the effectiveness of an investigational vaccine for the prevention of smallpox disease. Smallpox was one of the major c...

Evaluation of the Antipruritic Effect of Elidel (Pimecrolimus) in Non-atopic Pruritic Disease

The development of the topical calcineurin inhibitor pimecrolimus resulted in a significant improvement in the treatment of atopic dermatitis. In addition, an excellent amelioration of pru...

Clobetasol Versus Pimecrolimus for Vulvar Lichen Sclerosus

Lichen sclerosus (LS) is a skin condition of the external genitals (vulva) of women. LS causes vulvar itching, pain, and burning. In addition, LS causes scarring of the vulva which may cau...

Influence of Probiotics on Atopy, Immunological Responses and Gut Microflora - Follow-up to 5 Years

The investigators had conducted a double-blind, randomized placebo-controlled clinical trial studying the effects of 6 months probiotics supplementation from birth on allergic disease and...

Prevention of Asthma With Levocetirizine (36 Month Treatment) in Young Children Suffering From Eczema (Atopic Dermatitis) and Sensitized to Grass Pollen and House Dust Mite and Having Completed the Previous EPAAC Trial (NCT00152464)

Prolongation of the EPAAC™ trial - NCT00152464 (The Early Prevention of Asthma in Atopic Children). 36 months study to evaluate the efficacy and safety of levocetirizine (LCTZ) in preve...

Prevention of Asthma With Levocetirizine 18 Month Treatment in Infants (12 - 24 Months) Suffering From Eczema (Atopic Dermatitis) and Sensitized to Grass Pollen and/or House Dust Mite (HDM)

The Early Prevention of Asthma in Atopic Children (EPAAC™) . 24 months study to evaluate the efficacy and safety of levocetirizine (LCTZ) in preventing the onset of asthma in 12 to 24 mo...

Efalizumab for Eczema

The purpose of this study is to demonstrate a measurable improvement on a validated scale in a small population of adult patients with atopic dermatitis (eczema).

Neuroskin Forte for Dry Skin Relief in Eczema and Psoriasis

The purpose of this study is to assess the efficacy of Neuroskin Forte in relieving the symptoms of dry skin in adults with psoriasis or eczema.

Efficacy and Safety of Pimecrolimus Cream 1% in Patients (2 to 11 Years Old) With Mild to Moderate Facial Atopic Dermatitis

This study is not being conducted in the United States of America (USA). Atopic dermatitis, also called eczema, is characterized by redness, papulation (skin elevation) and pruritus (skin...

PubMed Articles [ 202 Associated PubMed Articles listed on BioPortfolio]

Antioxidant and anti-inflammatory activities of the phenolic extracts of Sapium sebiferum (L.) Roxb. leaves.

The leaves of Sapium sebiferum have long been used in Traditional Chinese Medicine (TCM) for the treatment of eczema, shingles, edema, swelling, ascites, scabs, and snakebites, among other maladies.

Exacerbation of symptoms in agricultural pesticide applicators with asthma.

PURPOSE: Exacerbation is a critical event in asthma management. We investigated whether exacerbation of symptoms is associated with farming exposures among agricultural pesticide applicators with asth...

Progress in Pediatrics in 2012: choices in allergy, endocrinology, gastroenterology, hematology, infectious diseases, neurology, nutrition and respiratory tract illnesses.

In this review, we summarize the progresses in allergy, endocrinology, gastroenterology, hematology, infectious diseases, neurology, nutrition and respiratory tract illnesses that have been published...

Anti-allergic drug discovery in China for eczema: current methods and future strategies.

Introduction: Eczema is a common childhood atopic disease associated with chronicity and impaired quality of life. As there is no cure for this disease, treatment relies on topical and systemic anti-a...

Childhood Allergies Affect Health-Related Quality of Life.

Objective. The majority of studies investigating the effects of allergy on the children's health-related quality of life (HRQoL) address one particular allergic disease, using a disease-specific HRQoL...

A metabolite-profiling approach allows the identification of new compounds from Pistacia lentiscus leaves.

Pistacia lentiscus L., commonly known as Mastic tree or lentisk, is a Mediterranean evergreen shrub widely used in traditional medicine to treat such diseases as eczema, diarrhoea, and throat infectio...

Effects of Pimecrolimus Compared with Triamcinolone Acetonide Cream on Skin Barrier Structure in Atopic Dermatitis: a Randomized, Double-blind, Right-Left Arm Trial.

Patients with atopic dermatitis (AD) have an epidermal barrier dysfunction, which allows invasion of allergens to occur. Stratum corneum skin barrier is formed by corneocytes and extracellular lipids...

Skin barrier dysfunction in non-lesional atopic eczema: the role of stratum corneum lipids.

Demodex blepharitis mimicking eyelid sebaceous gland carcinoma.

Sebaceous gland carcinoma (SGC) arises from the sebaceous glands of the ocular adnexa. It can present as a yellow nodule that may be ulcerated. It can also appear as a plaque-like lesion or as recurre...

Fatty-acid composition of maternal and umbilical cord plasma and early childhood atopic eczema in a Spanish cohort.

Background/objectives:Fatty-acid status during in-utero development might influence the risk of atopic diseases in early childhood. The aim of this work was to identify the relationship between matern...

Videos

DermTV - What is Eczema [DermTV.com Epi #173]

Eczema is often confused with different conditions or even dry skin, and thus, when people treat the latter two, they don't get any relief. In this episode o...

Medical and Biotech [MESH] Definitions

Eczema, Dyshidrotic

A recurrent eczematous reaction characterized by the development of vesicular eruptions on the palms and soles, particularly along the sides and between the digits. It is accompanied by pruritus, a burning sensation, and hyperhidrosis. The disease is self-limiting, lasting only a few weeks. (Dorland, 27th ed)

Sporidesmins

A group of related mycotoxins produced by the pasture fungus Pithomyces chartarum (formerly Sporidesmium bakeri); causes liver damage and facial eczema in cattle and sheep.

Wiskott-aldrich Syndrome

A rare, X-linked immunodeficiency syndrome characterized by ECZEMA; LYMPHOPENIA; and, recurrent pyogenic infection. It is seen exclusively in young boys. Typically, IMMUNOGLOBULIN M levels are low and IMMUNOGLOBULIN A and IMMUNOGLOBULIN E levels are elevated. Lymphoreticular malignancies are common.

Bacitracin

A complex of cyclic peptide antibiotics produced by the Tracy-I strain of Bacillus subtilis. The commercial preparation is a mixture of at least nine bacitracins with bacitracin A as the major constituent. It is used topically to treat open infections such as infected eczema and infected dermal ulcers. (From Goodman and Gilman, The Pharmacological Basis of Therapeutics, 8th ed, p1140)

Candidiasis, Cutaneous

Candidiasis of the skin manifested as eczema-like lesions of the interdigital spaces, perleche, or chronic paronychia. (Dorland, 27th ed)

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