Endocrine Disrupting Chemicals (EDCs) - Biotech, Pharma and Life Science Channel
- Endocrine disrupting chemicals (EDCs) consist of a diverse group of industrial chemicals and pharmacological agents.
- Evidence is accumulating that environmental chemicals (ECs) including endocrine-disrupting compounds (EDCs) can alter female reproductive development, fertility and onset of menopause.
- Endocrine disrupting chemicals (EDCs) with estrogenic activity have been similarly linked to an increased prostate cancer risk. Since it has been suggested that stem cells and cancer stem cells are potential targets of cancer initiation and disease management, it is highly possible that estrogens and EDCs influence the development and progression of prostate cancer through reprogramming and transforming the prostate stem and early stage progenitor cells.
Endocrine Disruptors
Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
PubMed Articles
Construction of long-wavelength fluorescein analogues and their application as fluorescent probes.
Born to dye: Five fluorescein analogues were synthesised. One analogue was found to emit in the NIR region with a high quantum yield, excellent photostability and good permeability. Three derivatives...
An organocatalytic asymmetric direct aldol addition reaction that involves cleavage of a carbon-carbon bond through the release of trifluoroacetate was developed. The protocol is wide in scope, genera...
The association between cytotoxic T-lymphocyte associated antigen 4 (CTLA-4) exon-1 +49 A/G polymorphism and Hashimoto's thyroiditis (HT) has been widely studied. The results, however, are mixed. This...
The unrelenting fall of the pharmacological treatment of obesity.
Nowadays pharmacological therapy to limit obesity has reached a critical stage: not only have Authorities limited the use of antiobesity drugs due to their proven inefficacy and dangerous side effects...
Antimicrobial peptides (AMPs) could become the next generation antibiotic compounds which can overcome bacterial resistance by disrupting cell membranes and it is essential to determine the factors un...
Microbial electrosynthesis is the biocathode-driven production of chemicals from CO2 and has the promise to be a sustainable, carbon-consuming technology. To date, microbial electrosynthesis of acetat...
Patient's comfort with and tolerability of thyroid core needle biopsy.
Recently, the core needle biopsy (CNB) has been proposed as a complementary test for thyroid nodules with inconclusive cytology by fine-needle aspiration (FNA). However, there have been no reports reg...
Lack of association between OSAS and hypothyroidism.
Abstract The kinin-kallikrein system (KKS) is an endogenous multiprotein cascade, the activation of which leads to triggering of the intrinsic coagulation pathway and enzymatic hydrolysis of kininogen...
News Articles
1-800-GO-VAPOR.com to Target Gas Station Owners with Chemical-Free Vapor Steam Cleaner Technology
The commercial-grade Ladybug Tekno 2350 Steam Vapor Sanitization System qualifies as a disinfection device for the EPA, making it more suitable than traditional hard-surface disinfectants for cleaning...
Bringing Biotech to Boats at BIO World Congress
At the 2013 BIO World Congress on Industrial Biotechnology in Montreal next month you’ll be able to see a Campion boat on the exhibit show floor. “What will a boat be doing on the show floor of an...
Smith Healthy Coffee: Announcing Health & Financial Changes in 2013
Coffee With a Healthy Twist is Changing the Lives of Many. Reno, NV (PRWEB) May 17, 2013 Creating positive changes in the areas of health and finances in 2013 is the recent announcement of a Healthy...
1-800-GO-VAPOR.com to Market Vapor Steam Cleaner to Orthodontists
The Professional-Grade Ladybug Tekno 2350 Steam Vapor Sanitization System qualifies as a disinfection device for the EPA, making it more suitable than traditional hard-surface disinfectants for many h...
[SK Chemicals] gets South Korean rights to two of [TheraVida]'s drug candidates
Pharmaceutical/life sciences company [SK Chemicals Co. Ltd.] has licensed exclusive South Korean development and marketing rights to [TheraVida Inc.]’s (reformulates existing drugs) Phase II {Toleni...
Home Secretary is Ignoring Advice Over Legal Highs Including her Experts
LONDON, May 16, 2013 /PRNewswire/ -- Founder of the drugs charity, Angelus, Maryon Stewart, described the Home Secretary as, "ignoring advice over Legal Highs including her own experts." The Chair of...
STERIS Launches VaproQuip Decontamination Room
Biological contamination can be present almost anywhere in a hospital. Aggressive pathogens on environmental surfaces, such as high-touch, difficult-to-clean surfaces of mobile equipment and furniture...
Pressure BioSciences, (OTCQB: PBIO), a company focused on developing its pressure cycling technology (PCT), says that researchers at Harvard Medical School have published a scientific paper describing...
Evonik selects OPX Biotechnologies for joint development of bio-based chemicals
OPX Biotechnologies, Inc. (OPXBIO) and Evonik Industries AG announced the two companies have entered into an agreement to jointly develop certain bio-based specialty chemicals. The joint-development...
1-800-GO-VAPOR.com Offers Vapor Steam Cleaners Guide
The new in-depth guide spells out the many uses of Ladybug vapor steam cleaners. Lake Forest, Illinois (PRWEB) May 16, 2013 Today, 1-800-GO-VAPOR.com, a national ecommerce company specializing in top...
Events
Smithers Viscient has brought together an exciting new event for June 2013, Environmental Science Forum.
An exhibition for producers and suppliers of raw materials and active pharmaceutical ingredients
Companies
TheAmerican Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Momentive Specialty Chemicals Inc.
Solazyme, Inc. is a renewable oil and bioproducts company and the leader in algal biotechnology. Founded in 2003 and headquartered in South San Francisco, Solazymeâs unique t...
Since its inception in 1963, Capitol Scientific has built a formidable enterprise by leveraging a vast portfolio of name brand products concentrated in high-purity & reagent chemi...
Union Pacific Corporation owns one of America's leading transportation companies. Its principal operating company, Union Pacific Railroad, links 23 states in the western two-th...
The E.T. Horn Company is employee owned and one of North Americaâs largest distributors, marketers and manufacturers of specialty chemicals, raw materials, and specialty ingr...
Verdezyne is an industrial biotechnology company using proven and proprietary metabolic pathway engineering tools to create unique yeast strains for cost-effective production of b...
ChemRisk LLC is a scientific consulting firm committed to helping clients develop sustainable solutions to a growing number of health and safety concerns. Specifically, the...
MeadWestvaco Corporation (NYSE: MWV), provides packaging solutions to many of the worldâs most-admired brands in the healthcare, beauty and personal care, food, beverage, hom...
Syapse is disrupting healthcare by bringing omics into routine medical use. Built on a powerful cloud-based semantic data platform, Syapse applications enable the generation and u...
Clinical Trials
Pelvic Pain in Women With Endometriosis
This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus. Standa...
Cell Lines From High-Risk Breast Tissue
Background: - Many risk factors for breast cancer have been identified, including family history, endocrine background, changes in breast tissue, cancer in one breast, radiation...
Marinobufagenin as a Target for DIGIBIND in Preeclampsia
Background: - Preeclampsia is a combination of high blood pressure and other potentially life-threatening symptoms. Preeclampsia occurs in up to 10% of pregnancies and is a...
The purpose of this study is to evaluate the treatment of a cancerous disease of the peritoneum with complete cytoreductive surgery with intraperitoneal chemohyperthermia using oxaliplatin...
Environmental Enterovirus Monitoring
From last decades, because of lacking the powerful quantitative methods, such as real-time qPCR, there is no environmental monitoring data about enterovirus transmission. If the major tra...
Letrozole in the Treatment of Advanced or Recurrent Hormone Receptor Positive Endometrial Cancer
In Western industrialized countries, endometrial cancer is the most common malignancy of the female reproductive tract. The general therapy options are surgery, radiotherapy, chemotherapy...
Efficacy and Safety of Asenapine With Placebo and Olanzapine (41021)(P05933)(COMPLETED)
Schizophrenia is a brain disease. The primary features of schizophrenia are characterized by Positive symptoms (symptoms that should not be there, inability to think clearly, to distinguis...
Efficacy and Safety of Asenapine With Placebo and Haloperidol (41023)(COMPLETED)
Schizophrenia is a brain disease. The primary features of schizophrenia are characterized by Positive symptoms (symptoms that should not be there, inability to think clearly, to distinguis...
Schizophrenia is a brain disease. The primary features of schizophrenia are characterized by Positive symptoms (symptoms that should not be there, inability to think clearly, to distinguis...
Efficacy and Safety of Asenapine With Placebo and Olanzapine (41022)(COMPLETED)
Schizophrenia is a brain disease. The primary features of schizophrenia are characterized by Positive symptoms (symptoms that should not be there, inability to think clearly, to distinguis...
Videos
Endocrine Disrupting Chemicals - Adam Law, MD
Continuing Medical Education (CME) Activity Jointly Sponsored by Physicians Scientists & Engineers for Healthy Energy and the Medical Society of the State of...
Medical and Biotech [MESH] Definitions
Toxicity Tests, Chronic
Experiments designed to determine the potential toxic effects of a long-term exposure to a chemical or chemicals.
Vascular Endothelial Growth Factor, Endocrine-gland-derived
A vascular endothelial growth factor whose expression is found largely restricted to the GONADS; ADRENAL CORTEX; and PLACENTA. It has similar biological activity to VASCULAR ENDOTHELIAL GROWTH FACTOR-A.
Carboxypeptidase H
A ZINC-containing exopeptidase primarily found in SECRETORY VESICLES of endocrine and neuroendocrine cells. It catalyzes the cleavage of C-terminal ARGININE or LYSINE residues from polypeptides and is active in processing precursors of PEPTIDE HORMONES and other bioactive peptides.
Receptor, Adenosine A3
A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of locations including the BRAIN and endocrine tissues. The receptor is generally considered to be coupled to the GI, INHIBITORY G-PROTEIN which causes down regulation of CYCLIC AMP.
Angiogenesis Modulating Agents
Agents that modulate the PHYSIOLOGIC ANGIOGENESIS process. This is accomplished by endogenous ANGIOGENIC PROTEINS and a variety of other chemicals and pharmaceutical agents.
