Endocrine paraneoplastic syndromes - Biotech, Pharma and Life Science Channel
PubMed Articles
Over-expression of integrin αvβ6 and increased numbers of cancer-associated fibroblasts (CAFs) play an important role in the development and progression of cancers. The aim of this study is to inves...
Precancerous colorectal tumors.
Preneoplastic lesions of colorectal carcinoma can be divided in non-serrated and serrated lesions. Non-serrated lesions include conventional adenomas (tubular, tubulovillous and villous) and dysplasia...
The association between cytotoxic T-lymphocyte associated antigen 4 (CTLA-4) exon-1 +49 A/G polymorphism and Hashimoto's thyroiditis (HT) has been widely studied. The results, however, are mixed. This...
The unrelenting fall of the pharmacological treatment of obesity.
Nowadays pharmacological therapy to limit obesity has reached a critical stage: not only have Authorities limited the use of antiobesity drugs due to their proven inefficacy and dangerous side effects...
Severe autoimmune hemolytic anemia with renal neoplasm.
Autoimmune hemolytic anemia is a type of hemolytic anemia characterized by autoantibodies directed against red blood cells shortening their survival. When autoimmune hemolytic anemia is secondary to a...
Bilastine for the treatment of urticaria.
Introduction: Urticaria is a highly prevalent disease among people. First-choice treatment continues to be centred on the second-generation H1 antihistamines, including a wide group of drugs with a be...
Dabigatran and acute coronary syndromes.
Expanding the phenotype of IQSEC2 mutations: truncating mutations in severe intellectual disability.
Intellectual disability (ID) is frequent in the general population, with 1 in 50 individuals directly affected worldwide. The multiple etiologies include X-linked ID (XLID). Among syndromic XLID, few...
Gastrointestinal and hepatic manifestations of mitochondrial disorders.
Inherited defects of oxidative phosphorylation lead to heterogeneous, often multisystem, mitochondrial diseases. This review highlights those mitochondrial syndromes with prominent gastrointestinal an...
Von Hippel Lindau (VHL) syndrome is an autosomal dominant disorder characterized by benign and malignant tumors. This study presents the clinical and genetic features of VHL syndrome in a Turkish fami...
News Articles
The Detroit Institute for Children Needs Your Vote To Win $25,000
The Organization is Competing in Art Van Furniture’s Third Annual Million Dollar Charity Challenge Bonus Challenge The Detroit Institute for Children (DIC) needs your help...
Smith Healthy Coffee: Announcing Health & Financial Changes in 2013
Coffee With a Healthy Twist is Changing the Lives of Many. Reno, NV (PRWEB) May 17, 2013 Creating positive changes in the areas of health and finances in 2013 is the recent announcement of a Healthy...
FDA approves Novartis juvenile arthritis drug
The FDA has approved Novartis’ drug Ilaris (canakinumab) for the treatment of active systemic juvenile idiopathic arthritis (SJIA) in patients aged two years and older. Ilaris is the first interleuk...
Nordion, Navidea sign contract manufacturing agreement
Nordion has entered into a contract manufacturing agreement with Navidea Biopharmaceuticals for NAV5001 a diagnostic imaging agent used to detect Parkinsonian Syndromes and Dementia with Lewy Bodies.
MARC Travel Awards announced for the ENDO 2013 95th Annual Meeting
(Federation of American Societies for Experimental Biology) FASEB MARC Program has announced the travel award recipients for The Endocrine Society 95th Annual Meeting in San Francisco, CA from June 15...
Onconova Therapeutics, Inc., a clinical-stage biopharmaceutical company, today announced that new safety and clinical activity data from its Phase 2 ONTARGET study w...
Nordion Signs Contract Manufacturing Agreement with Navidea Biopharmaceuticals
Nordion Inc. (TSX: NDN) (NYSE: NDZ), a leading provider of products and services to the global health science market, today announced it has signed a contract manufacturing agreem...
Targeting inflammasomes in rheumatic diseases
As molecular complexes that promote inflammation, inflammasomes have been implicated in several autoimmune and autoinflammatory disorders, including cryopyrin-associated periodic syndromes and microcr...
Genomind Releases Statement Supporting NIMH Announcement to Move Away From DSM Categories
CHALFONT, PA--(Marketwired - May 14, 2013) - Genomind, a personalized medicine company, has released a statement in response to the National Institute of Mental Health's (NIMH) announcement by Direc...
Hypothyroidism Revolution Review and Hypothyroid Diet Plan Revealed by Daily Gossip
Denver, Colorado (PRWEB) May 13, 2013 Data from the National Endocrine and Metabolic Diseases Information Service estimates that about 4.6 percent of the US population older than 12 have a form of...
Events
Smithers Viscient has brought together an exciting new event for June 2013, Environmental Science Forum.
Companies
Physician Therapeutics is a division of Targeted Medical Pharma, Inc., a specialty pharmaceutical company that develops and sells prescription medical foods to physi...
TheAmerican Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Physician Therapeuticsâ medical foods are amino acid based, FDA-regulated medications specially formulated to meet the bodyâs increased nutritional requirements of disea...
The American Association of Clinical Endocrinologists
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
The Myelodysplastic Syndromes Foundation, Inc. is a multi-disciplinary, international organization devoted to the prevention, treatment, and study of the myelodysplastic syndromes...
TONIX Pharmaceuticals is developing new treatments for challenging disorders of the central nervous system. The Companyâs most advanced program targets fibromyalgia syndrome...
AlphaCore Pharma is an Ann Arbor-based private company focused on the development of ACP-501 as a therapy for acute coronary syndromes, and other high-risk atherosclerosis conditi...
The American Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
NPS Pharmaceuticals is developing new treatment options for patients with rare gastrointestinal and endocrine disorders. The company is currently advancing two Phase 3 registratio...
Clinical Trials
Cell Lines From High-Risk Breast Tissue
Background: - Many risk factors for breast cancer have been identified, including family history, endocrine background, changes in breast tissue, cancer in one breast, radiation...
Randomized Study of ON 01910.Na in Refractory Myelodysplastic Syndrome Patients With Excess Blasts
The primary objective of this study is to compare overall survival (OS) in patients receiving ON 01910.Na + best supportive care (BSC) to OS of patients receiving BSC in a population of pa...
Host Immune Response to Clostridium Difficile Infection in Inflammatory Bowel Disease Patients
The inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's disease (CD) are chronic conditions affecting approximately 1.4 million Americans. The burden of Clostridium dif...
RATIONALE: Sorafenib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the cancer. PURPOSE: This randomized phase I...
Botox as a Treatment for Interstitial Cystitis in Women
Patients with interstitial cystitis have been well documented to have pelvic floor muscle tenderness as well as pain on bladder distension. Some investigators have even suggested that pel...
The purpose of this study is to evaluate the treatment of a cancerous disease of the peritoneum with complete cytoreductive surgery with intraperitoneal chemohyperthermia using oxaliplatin...
PROSPECT: An Imaging Study in Patients With Unstable Atherosclerotic Lesions
PROSPECT is a multi-center prospective registry of Acute Coronary Syndromes (ACS) patients with single or double vessel coronary artery disease. Approximately 700 patients with ACS will be...
Supporting Effect of Dronabinol on Behavioral Therapy in Fibromyalgia and Chronic Back Pain
It is known, that a so called "pain memory" usually evolves in chronic pain syndromes which both aggravates the disorder and modifies the patients pain perception. Thus, the principal obje...
The Study of Human Atherosclerosis by Polarization-Sensitive Optical Coherence Tomography
Atherosclerosis is unquestionably the leading cause of morbidity and mortality in developed countries, and the world-wide importance of acute vascular syndromes is increasing. Rupture of a...
Letrozole in the Treatment of Advanced or Recurrent Hormone Receptor Positive Endometrial Cancer
In Western industrialized countries, endometrial cancer is the most common malignancy of the female reproductive tract. The general therapy options are surgery, radiotherapy, chemotherapy...
Videos
Paraneoplastic Syndromes
Pathology - Neoplasms - Paraneoplastic Syndromes - https://dl.dropbox.com/u/17388924/Paraneoplastic%20Syndromes.jpg.
Medical and Biotech [MESH] Definitions
Vascular Endothelial Growth Factor, Endocrine-gland-derived
A vascular endothelial growth factor whose expression is found largely restricted to the GONADS; ADRENAL CORTEX; and PLACENTA. It has similar biological activity to VASCULAR ENDOTHELIAL GROWTH FACTOR-A.
Carboxypeptidase H
A ZINC-containing exopeptidase primarily found in SECRETORY VESICLES of endocrine and neuroendocrine cells. It catalyzes the cleavage of C-terminal ARGININE or LYSINE residues from polypeptides and is active in processing precursors of PEPTIDE HORMONES and other bioactive peptides.
Receptor, Adenosine A3
A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of locations including the BRAIN and endocrine tissues. The receptor is generally considered to be coupled to the GI, INHIBITORY G-PROTEIN which causes down regulation of CYCLIC AMP.
Receptor, Angiotensin, Type 1
An angiotensin receptor subtype that is expressed at high levels in a variety of adult tissues including the CARDIOVASCULAR SYSTEM, the KIDNEY, the ENDOCRINE SYSTEM and the NERVOUS SYSTEM. Activation of the type 1 angiotensin receptor causes VASOCONSTRICTION and sodium retention.
Piscirickettsiaceae Infections
Infections with bacteria of the family PISCIRICKETTSIACEAE, causing septicemic disease of salmonid fish (SALMONIDAE). Piscirickettsia-like bacteria are also associated with disease syndromes in non-salmonid fish.
