Esophageal lead - Biotech, Pharma and Life Science Channel
PubMed Articles
Treatment for hepatitis C virus-induced portal hypertension in leukemic children.
Children with acute leukemia are at high risk of hepatitis C infection, either by immunosuppression secondary to chemotherapy or by multiple transfusions of blood products during the course of the dis...
Oxidative stress is considered one of the main events that lead to aging and neurodegeneration. Antioxidant treatments used to counteract oxidative damage have been associated with a wide variety of s...
Trichinella: What is going on during nurse cell formation?
Recent molecular studies have revealed that many genes are mobilized during nurse cell formation, including those involved in activation and proliferation of satellite cells, dedifferentiation, cell c...
Coronary Sinus Obstruction after Atrioventricular Canal Defect Repair.
The coronary sinus can become obstructed with any instrumentation at or near the ostium such as in atrioventricular canal defect repairs. This complication may lead to a wide range of consequences inc...
Perovskite-Structured PbTiO3 Thin Films Grown from a Single-Source Precursor.
Perovskite-structured lead titanate thin films have been grown on FTO-coated glass substrates from a single-source heterometallic molecular complex, [PbTi(μ2-O2CCF3)4(THF)3(μ3-O)]2 (1), which was is...
One-step synthesis of peptide-programmed QDs as ready-to-use nanoprobes.
We developed a facile one-step method to produce ready-to-use quantum dots based on a peptide sequence containing a hexahistidine(his6-tag), poly(ethylene glycol) (PEG), and a functional group, which...
Boerhaave's syndrome is spontaneous rupture of the esophagus, a rare condition with high mortality that occurs most often after forceful vomiting. Polyethylene glycol (PEG) solution is the most common...
Biodegradable stent for the treatment of a colonic stricture in Crohn's disease.
Biodegradable polydioxanone stents were developed for the treatment of refractory benign esophageal strictures but have been suggested as a new therapeutic option for intestinal strictures. The primar...
Esophageal cancer is among the leading causes of cancer-related deaths worldwide. The management of patients with esophageal cancer is determined to a large extent by patient performance status, locat...
We report the emerging role of microRNA (miRNA) deregulation associated with activation of an oncogene SOX4 (a member of the SRY-related HMG-box) in esophageal carcinoma. Paired esophageal cancer and...
News Articles
Endoscopic ablation in patients with Barrett’s esophagus containing confirmed low-grade dysplasia reduces the relative risk for disease progression by 94% as compared to control...
10 Warning Signs: What Your Mouth Says About Your Health
NEW YORK, May 22, 2013 /PRNewswire/ -- If the eyes are the windows to your soul, then your mouth is the gateway to your overall health. Research has found a surprising number of links betwe...
Genetic variation helps predict survival in some cases of pulmonary fibrosis, study finds
Research into genetic features of pulmonary fibrosis by physicians and scientists at the University of Colorado School of Medicine may lead to improved treatment of this deadly lung disease, according...
Failure to use linked health records may lead to biased disease estimates
Failure to use linked electronic health records may lead to biased estimates of heart attack incidence and outcome, warn researchers in a paper published in BMJ today.
Coffee Cuts Biliary Duct Risk (CME/CE)
ORLANDO (MedPage Today) -- Coffee consumption helped protect against the autoimmune liver disease known as primary sclerosing cholangitis (PSC), which can lead to transplantation or death, a researche...
New Research Identifies Cost-Savings For Patients Suffering From GERD
ORLANDO, Fla., May 21, 2013 /PRNewswire-USNewswire/ -- A study presented at Digestive Disease Week® (DDW) suggests that more objective testing may substantially reduce the cost and risk o...
New diagnostic test for lymphatic filariasis
A new diagnostic test for a worm infection that can lead to severe enlargement and deformities of the legs and genitals is far more sensitive than the currently used test, according to results of a fi...
Karyopharm raises $48.2m to inhibit nuclear export
Karyopharm Therapeutics raised $48.2 million in a Series B funding round to start separate Phase II/III studies in hematological malignancies and solid tumors early next year for its lead human drug c...
Peregrine flies higher on Phase III bavituximab plan
Peregrine Pharmaceuticals closed up 18.8% at $1.83 per share after the company said it reached an agreement with the US FDA on a Phase III clinical trial design for its beleaguered lead product cand...
Covance Pushes Further into Biologics Development, Lead Optimization
Although preclinical work for CROs has fallen flat in recent quarters, Covance is looking to take advantage of the industry’s shift to early biologic developments and lead optimization.
Events
Companies
Tokai Pharmaceuticals is a U.S. biopharmaceutical company focused on developing new treatments for prostate cancer. The companyâs lead drug candidate, TOK-001, is the first i...
Instem is a world-leading information solutions provider for the Life Sciences - accelerating drug and chemical development by increasing client productivity and enhancing the pro...
Provectus Pharmaceuticals, Inc.
Provectus Pharmaceuticals specializes in developing oncology and dermatology therapies. Its lead oncology agent, PV-10, is designed to selectively target and destroy cancer cells...
Carrington Colleges Group offer programs through two separate institutions, Carrington College® and Carrington College® California, to prepare students for careers in health...
Retrophin is a biotechnology company focused on discovering and developing treatments for rare and life-threatening diseases. Retrophin is currently developing treatments for foca...
Biosense Webster, Inc., a Johnson & Johnson company, pioneered electrophysiology diagnostic catheters more than 30 years ago and continues to lead the industry as an innovative pr...
Cell Medica is a clinical stage cellular therapeutics company engaged in the development and delivery of cellular immunotherapy treatment strategies for infectious disease and can...
Accelarad, an Atlanta-based company, is a market leader in medical image cloud computing. With the launch of SeeMyRadiology.com - its new online medical exchange community - Accelarad will continue to...
Opsona is a leading immunology drug development company, focused on novel therapeutic approaches to key targets of the innate immune system associated with a wide range of majo...
Founded in 2007, Solaris Paper is a Delaware-incorporated, California-based manufacturer of tissue and towel products for the Away-from-Home commercial marketplace delivering prod...
Clinical Trials
Ventricular Arrhythmias in Uremic Cardiomyopathy
There is a certain gene called sarcoplasmic reticulum gene (SERCA2a), which is found in heart muscle. This gene is also found in blood vessels and skin tissue. When active this gene builds...
Rituximab and Gemcitabine for Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Rituximab has been demonstrated to sensitize drug-resistant NHL cells to the cytotoxic actions of several chemotherapy agents by enhancing sensitivity of tumor cells to chemotherapy-induce...
myoARRAY and TcLandscape Analysis for the Diagnosis of Inflammatory Myopathies
The diagnosis of the different forms of inflammatory myopathies (polymyositis, dermatomyositis, inclusion-body myositis...) remains difficult which may lead to unappropriate patient care....
Risk Factors for Gastric Disease in Pediatric Helicobacter Pylori (H. Pylori)
Helicobacter pylori (Hp) is a major cause of chronic-active gastritis and primary duodenal ulcers, and is strongly linked to gastric cancer. Most Hp infections worldwide are acquired in c...
Cetuximab, Capecitabine, Oxaliplatin and Bevacizumab in Advanced Colorectal Cancer
This is a study to assess the efficacy and safety of the addition of cetuximab to the combined regimen of capecitabine, oxaliplatin and bevacizumab in patients with previously untreated ad...
Rapid Emergency Department Heart Failure Outpatient Trial (REDHOT II)
The purpose of this study is to test whether physicians can make more informed treatment, admission, and discharge decisions related to patient care by having serial Triage® BNP test resu...
Perioperative Effect of Atenolol on Cytokine Profiles
Studies have shown that beta-blockers such as atenolol when given in the perioperative period reduce morbidity and mortality. One study showed that atenolol given just during the surgery...
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. Indeed, certain oncogenic types of HPV can infect the cervix (part of the ut...
Pre-hospital Administration of Thrombolytic Therapy With Urgent Culprit Artery Revascularization
The PATCAR study has been designed to test the hypothesis that the strategy of pre-hospital use of a "clot busting" (thrombolytic) drug followed with emergent heart catheterization includi...
Chemoradiation and Tetrathiomolybdate (TM) in Patients With Esophageal Carcinoma
Surgery has been the standard of care for esophageal cancer for many years, with limited success. At present, several studies are underway nationwide which utilize chemotherapy combined w...
Videos
Acid Reflux Leads To Esophageal Cancer; Both Sleeve & Band Result Patients With Acid Reflux
Acid Reflux Leads to Esophageal Cancer; Both Sleeve & Band Result in Up to 30% of patients with Acid Reflux GASTROESOPHAGEAL REFLUX IS COMMON AFTER BOTH SLEE...
Medical and Biotech [MESH] Definitions
Epigenesis, Genetic
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
Diverticulosis, Esophageal
A pathological condition characterized by the presence of a number of ESOPHAGEAL DIVERTICULA in the ESOPHAGUS.
Clostridium Histolyticum
A species of gram-positive, strongly proteolytic bacteria in the family Clostridiaceae. It contains several forms of COLLAGENASE whose action can lead to GAS GANGRENE in humans and HORSES.
Myopia, Degenerative
Excessive axial myopia associated with complications (especially posterior staphyloma and CHOROIDAL NEOVASCULARIZATION) that can lead to BLINDNESS.
Esophageal Sphincter, Lower
The physiologic or functional barrier to GASTROESOPHAGEAL REFLUX at the esophagogastric junction. Sphincteric muscles remain tonically contracted during the resting state and form the high-pressure zone separating the lumen of the ESOPHAGUS from that of the STOMACH. (Haubrich et al, Bockus Gastroenterology, 5th ed., pp399, 415)
