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Exposure to teratogens - Biotech, Pharma and Life Science Channel

13:37 EDT 23rd May 2013 | BioPortfolio

PubMed Articles [ 5286 Associated PubMed Articles listed on BioPortfolio]

The suppression of hematopoiesis function in Balb/c mice induced by prolonged exposure of microcystin-LR.

Microcystins (MCs) cause normocytic anemia in patients in a hemodialysis unit in Caruaru, Brazil in 1996, but the underlying mechanisms are still unclear. In the present study, Balb/c mice were intrap...

Everolimus: A Guide to Its Use in Liver Transplantation.

The mammalian target of rapamycin inhibitor everolimus (Zortress(®), Certican(®)) was recently approved in the USA and a number of EU countries for use in combination with a reduced dosage of tacrol...

Biological response of high-back crucian carp (Carassius auratus) during different life stages to wastewater treatment plant effluent.

This study presents the adverse effects of endocrine disrupting chemicals (EDCs) in effluent of wastewater treatment plants (WwTPs) on fish health. A study of chronic exposure to WwTPs effluent for 10...

Spatial and Temporal Variation in the Diet of Tree Swallows: Implications for Trace-Element Exposure After Habitat Remediation.

Emerging aquatic insects play a key role in transporting aquatic contaminants into terrestrial ecosystems. Tree swallows are frequently the focus of studies examining this movement because they are th...

Daily Short Message Service Surveys to Measure Sexual Behavior and Pre-exposure Prophylaxis Use Among Kenyan Men and Women.

Pre-exposure prophylaxis (PrEP) is a novel HIV prevention strategy which requires high adherence. We tested the use of daily short message service (i.e., SMS/text message) surveys to measure sexual be...

Childhood exposure to Libby amphibole during outdoor activities.

Residents of Libby, MT were exposed to amphibole asbestos through multiple environmental pathways. Previous exposure characterization has primarily relied on qualitative report of these exposure activ...

Short-term risk of hospitalization for asthma or bronchiolitis in children living near an aluminum smelter.

Few studies have measured the effect of short-term exposure to industrial emissions on the respiratory health of children. Here we estimate the risk of hospitalization for asthma and bronchiolitis in...

Glycoalkaloid and calystegine levels in table potato cultivars subjected to wounding, light, and heat treatments.

Potato tubers naturally contain a number of defense substances, some of which are of major concern for food safety. Among these substances are the glycoalkaloids and calystegines. We have here analyze...

Slow Avoidance Response to Contaminated Sediments Elicits Sublethal Toxicity to Benthic Invertebrates.

Advanced analytical techniques have identified the heterogeneity of sediments in aquatic environments which may impact the exposure of benthic organisms to contaminants. Acute and chronic toxicity ass...

Monte Carlo simulation of age-dependent radiation dose from alpha- and beta-emitting radionuclides to critical trabecular bone and bone marrow targets.

Alpha (α) particles and low-energy beta (β) particles present minimal risk for external exposure. While these particles can induce leukemia and bone cancer due to internal exposure, they can also be...

News Articles [ 2229 Associated News Articles listed on BioPortfolio]

Exposure To Traffic-Related Air Pollution In Early Years Linked To Hyperactivity

Early-life exposure to traffic-related air pollution was significantly associated with higher hyperactivity scores at age 7, according to new research from the University of Cincinnati (UC) and Cincin...

Intermountain Healthcare Launches Nation’s First System to Measure and Report Cumulative Medical Radiation Exposure

In recent years, new medical knowledge has raised concerns about the safety of radiation used in some medical diagnostic imaging tests. But until now, a program to accurately meas...

Childhood exposure to Libby amphibole during outdoor activities

Swine flu pandemic of 2009 more deadly for younger adults

As the world prepares for what may be the next pandemic strain of influenza virus, in the H7N9 bird flu, a new study reveals that the 2009 H1N1 swine flu pandemic was deadliest for people under the ag...

Swine flu pandemic of 2009 more deadly for younger adults, study finds

As the world prepares for what may be the next pandemic strain of influenza virus, in the H7N9 bird flu, a new UC Irvine study reveals that the 2009 H1N1 swine flu pandemic was deadliest for people un...

Common Chemical In Plastics Linked To Elevated Bloor Pressure In Kids

Brett Smith for redOrbit.com - Your Universe Online From BPA in plastic water bottles to mercury in fish, dangerous chemicals seem to be lurking in every corner these days. According to a new study f...

Smart Sun Choices With Ascenta Skin: Just one teaspoon a day helps to keep UV damage away!

NEW YORK, May 22, 2013 /PRNewswire/ -- Memorial Day weekend marks the unofficial start of summer and the beginning of extra time spent basking in the sun.  While a little dose of Vitamin D i...

New Pong Technology Smartphone and Tablet Cases Marry Science and Art

Designed by IDEO, the New Cases Provide a Glimpse of the Embedded Pong Antenna That Reduces User Exposure to Wireless Energy and Optimizes Device Performance Pong Resea...

Just 2 Months' Exposure to Anticholinergics Affects Cognition

Physicians should consider alternate medications or nonpharmacologic approaches to treat sleep problems, urinary incontinence, and other ailments, researchers say. Medscape Medical News

Dietary exposure to certain plastics may cause metabolic and hormonal abnormalities in children

Plastic additives known as phthalates (pronounced THAL-ates) are odorless, colorless and just about everywhere: They turn up in flooring, plastic cups, beach balls, plastic wrap, intravenous tubing an...

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Companies [ 24 Associated Companies listed on BioPortfolio]

FONEMED

With its 15 years of industry experience and URAC-accreditation, FONEMED maintains a roster of thousands of medical and management personnel, proprietary health information system...

Virtual Corporation

Virtual Corporation is a software and consulting services company that assists organizations to implement sustainable business continuity (BC) and COOP programs. Virtual Corporati...

Radimetrics

Radimetrics provides radiation dose monitoring and management software to hospitals and imaging centers. Radimetrics’ flagship product, eXposure™ is a single-system solu...

AspenBio Pharma, Inc.

AspenBio Pharma, Inc. is an emerging in vitro diagnostic company focused on obtaining FDA clearance for its lead product, AppyScore, which is a unique blood-based test in developm...

Nocimed, LLC

Nocimed, LLC is a privately held Delaware limited liability company with its principal operations based in Redwood City, CA. Nocimed was founded in 2008 to develop technologies fo...

Baron & Budd, P.C. .

The national mesothelioma law firm of Baron & Budd, P.C. has a more than 30-year history of “Protecting What’s Right” for asbestos sufferers and their families. As...

Pong Research Corporation

Founded in 2010, Pong is the world’s leading maker of cell phone and iPad cases that protect users from the wireless device radiation that the World Health Organization class...

Symbiotic Research Services

SR is a contract research organization (CRO) which is licensed to conduct research with radio labeled C-14 materials. SR has been inspected by the US-EPA and the NJ-DEP Division o...

AMI Research

AMI Research provides equity research coverage for promising companies that do not have traditional Wall Street analyst coverage. Coverage by AMI ensures an objective explanation...

Crossix

As the only company founded and focused on a consumer-centric healthcare analytics approach, Crossix is the industry standard by which Top 10 Pharma companies plan, measure and op...

Clinical Trials [ 770 Associated Clinical Trials listed on BioPortfolio]

Immune Response to Hepatitis C Virus

This study will identify and characterize immune factors involved in hepatitis C infection and elimination of the virus. Individual responses to hepatitis C infection vary; some people ar...

Study of Markers of Cosmic Radiation Exposure and Effect Among Flight Crews

Ionizing radiation efficiently induces chromosomal aberrations (CA) and several studies of CA have now been conducted among small groups of flight crews. However, most of the studies only...

A Multinational, Open-Label, Non-Controlled Trial on Safety, Efficacy and Pharmacokinetics of NNC 0129-0000-1003 in Previously Treated Paediatric Patients With Severe Haemophilia A

This trial is conducted globally. The aim of the trial is to investigate safety, efficacy and pharmacokinetics (the exposure of the trial drug in the body) of NNC 0129-0000-1003 (N8-GP) in...

1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain

We will conduct a 12-week, randomized open label study, comparing usual care (UC) antipsychotic treatment (aripiprazole, quetiapine, risperidone) with ziprasidone (ZIP) in children and ado...

First Human Dose Trial of NNC0195-0092 in Healthy Subjects

This trial is conducted in Europe. The aim of this trial is to assess safety, tolerability, pharmacokinetics (the exposure of the trial drug in the body) and pharmacodynamics (the effect o...

Paroxetine-CR to Treat Post-Traumatic Stress Disorder (PTSD) Symptomatic After Initial Exposure Therapy

Both pharmacotherapeutic and psychosocial interventions have domenstrated efficacy for PTSD. However, although these interventions can be helpful, many patients remain symptomatic despite...

The Use of Kineret (Anakinra) in the Treatment of Familial Cold Urticaria

An open labelled trial of Kineret (anakinra) induction therapy (100mg./day) in over a four week period in the treatment of Familial Cold Urticaria. Familial Cold Urticaria (FCU) is a rare...

Genesis of Scleroderma: Role of Environmental Factors in 100 Patients With Scleroderma and 300 Controls

Scleroderma is an autoimmune disease of unknown origin. Recently, the role of environmental factors, and particularly toxic drug exposure, in the genesis of scleroderma has been suggested....

Efficacy of Anti-Tubercular Vaccination in Multiple Sclerosis

The frequency of auto-immune diseases (including multiple sclerosis) is increasing in industrialised countries. According to an hypothesis which is receiving a wide international credit,...

Study to Describe the Allergic Reactions to Factor IX in Patients With Hemophilia B

Retrospective, multicenter study in patients with hemophilia B. This study will be placed at 20 to 50 hemophilia treatment centers in North America and the EU, and is designed to estimate...

Videos

Alcohol consumption during pregnancy

One of the most dramatic aspects of alcohol abuse is its consumption by pregnant women since alcohol freely crosses placenta and reaches developing embryo or...

Medical and Biotech [MESH] Definitions

Toxicity Tests, Chronic

Experiments designed to determine the potential toxic effects of a long-term exposure to a chemical or chemicals.

Tomography, Spiral Computed

Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.

Photobleaching

Light-induced change in a chromophore, resulting in the loss of its absorption of light of a particular wave length. The photon energy causes a conformational change in the photoreceptor proteins affecting PHOTOTRANSDUCTION. This occurs naturally in the retina (ADAPTATION, OCULAR) on long exposure to bright light. Photobleaching presents problems when occurring in PHOTODYNAMIC THERAPY, and in FLUORESCENCE MICROSCOPY. On the other hand, this phenomenon is exploited in the technique, FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING, allowing measurement of the movements of proteins and LIPIDS in the CELL MEMBRANE.

Microbubbles

Very small encapsulated gas bubbles (diameters of micrometers) that can be used as CONTRAST MEDIA, and in other diagnostic and therapeutic applications. Upon exposure to sufficiently intense ultrasound, microbubbles will cavitate, rupture, disappear, release gas content, etc. Such characteristics of the microbubbles can be used to enhance diagnostic tests, dissolve blood clots, and deliver drugs or genes for therapy.

Embryo Culture Techniques

The technique of maintaining or growing mammalian EMBRYOS in vitro. This method offers an opportunity to observe EMBRYONIC DEVELOPMENT; METABOLISM; and susceptibility to TERATOGENS

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