Eye disease - Biotech, Pharma and Life Science Channel

15:20 EST 4th March 2015 | BioPortfolio

PubMed Articles [14477 Associated PubMed Articles listed on BioPortfolio]

Evaluation of Patients' Knowledge Regarding Smoking and Chronic Pancreatitis: A Pilot Study.

Over the last decade, a strong association has been found between smoking and chronic pancreatitis. Some studies suggest that smoking may be a more important cause of chronic pancreatitis than alcohol...

Proangiogenic potency of MUC18 in arteriosclerotic disease.

Stenotic peripheral and dilatative arteriosclerotic diseases have different pathomechanism although associations between both diseases are well known. The adhesion molecule MUC18 is a cell membrane gl...

Deficiencies with current aortic endografts.

Endovascular aortic aneurysm repair (EVAR) has currently replaced open surgical repair as the primary method for treating aneurysm disease of the abdominal aorta and common iliac artery. Current EVAR ...

Management of patients with psoriatic arthritis.

: Psoriatic arthritis is a chronic inflammatory arthritis condition. If left untreated, patients with psoriatic arthritis may suffer pain, reduced quality of life, joint destruction, and disability. U...

Association of catastrophic biaxial fracture of the proximal sesamoid bones with bony changes of the metacarpophalangeal joint identified by standing magnetic resonance imaging in cadaveric forelimbs of Thoroughbred racehorses.

Objective-To compare bony changes in the metacarpophalangeal joint (MCPJ) of racehorses with (cases) and without (controls) biaxial proximal sesamoid bone (PSB) fracture as determined by 2 grading sca...

The HLA-C*04: 01/KIR2DS4 gene combination and human leukocyte antigen alleles with high population frequency drive rate of HIV disease progression.

The objective of this study is to identify human leukocyte antigen (HLA) class I and killer-cell immunoglobulin-like receptor (KIR) genotypes associated with different risks for HIV acquisition and HI...

Preventing group B streptococcal infections in newborns.

Despite advances in intrapartum antibiotic prophylaxis (IAP), group B streptococcal infection continues to be a predominant cause of early-onset disease in neonates. About 2% of neonates exposed to gr...

Do little embryos make big decisions? How maternal dietary protein restriction can permanently change an embryo.

Periconceptional environment may influence embryo development, ultimately affecting adult health. Here, we review the rodent model of maternal low-protein diet specifically during the preimplantation ...

Predicting Cognitive Function from Clinical Measures of Physical Function and Health Status in Older Adults.

Current research suggests that the neuropathology of dementia-including brain changes leading to memory impairment and cognitive decline-is evident years before the onset of this disease. Older adults...

Prevalence of Vitamin D Deficiency in Sickle Cell Disease: A Systematic Review.

Vitamin D deficiency has emerged as a public health focus in recent years and patients with sickle cell disease (SCD) reportedly have a high prevalence of the condition. Our objectives were to summari...

News Articles [5528 Associated News Articles listed on BioPortfolio]

Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase

P4-ATPases translocate aminophospholipids, such as phosphatidylserine (PS), to the cytosolic leaflet of membranes. PS is highly enriched in recycling endosomes (REs) and is essential for endosomal mem...

Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management—A KDIGO consensus report

Baxter acquires SuppreMol for innovative approach to autoimmune disease

Baxter's Bioscience Business has acquired SuppreMol for €200m in what the privately-held German firm's CEO called "a good day for both companies."

WebMD Health Services Receives NCQA Disease Management Accreditation

NEW YORK, March 4, 2015 /PRNewswire/ -- WebMD Health Services announced it recently received Patient-Oriented Disease Management Accreditation from the National Committee for Quality Assurance (N...

NYS Legislators Honor Academy Award-winning Actress Kathy Bates for National Lymphedema Awareness Day March 6th.

Lymphatic Education & Research Network (LE&RN) announced today that Spokesperson Kathy Bates is being honored by the New York State Assembly and Senate for h...

Cell powerhouse sequencing technology provides deeper look at inherited disease risk

A new sequencing technique may provide a clearer picture of how genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's inherited risk for diabetes, he...

Tricida Announces Closing of $30M Series B Financing

Company raises sufficient funding to enable first in human studies for lead candidate TRC101 in patients with complications of renal disease Tricida, Inc., a privately-held bi...

Arrowhead to Present at 2015 Barclays Global Healthcare Conference

Arrowhead Research Corporation (NASDAQ:ARWR), a biopharmaceutical company developing targeted RNAi therapeutics, today announced that Arrowhead’s president and chief executive o...

Study reveals mechanism behind most common form of inherited Alzheimer's disease

A study from researchers at Massachusetts General Hospital (MGH) and Brigham and Women's Hospital (BWH) reveals for the first time exactly how mutations associated with the most common form of inherit...

Psychiatric disorders: A zebrafish model of ADHD

Per1b-mutant zebrafish exhibit symptoms that mimic those of attention-deficit hyperactivity disorder and can be used to provide insight into the pathogenic disease mechanisms.

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Companies [295 Associated Companies listed on BioPortfolio]

Newron Pharmaceuticals S.p.A.

Newron (SIX: NWRN) is a biopharmaceutical company focused on the development of novel therapies for patients with diseases of the central nervous system (CNS) and pain. The Compan...

AqueSys, Inc.

AqueSys, Inc. is a privately-held company headquartered in Irvine, California. The company is focused on the research, development, manufacturing and distribution of implantable devices used to treat ...

National Forum for Heart Disease & Stroke Prevention

The National Forum for Heart Disease and Stroke Prevention builds a collective voice for a heart-healthy and stroke-free society through its collaborative policy and programmatic ...

Plaxgen, Inc.

Privately-held Plaxgen is developing diagnostics in atherosclerosis, Alzheimer’s disease, and other plaque-related diseases, using its proprietary Plaque Array technology. ...

Rainbow Medical

Rainbow Medical, a private operational investment company, currently holds a portfolio of 12 companies that are developing products for the treatment of a range of chronic indicat...

Newron Pharmaceuticals SpA

Newron Pharmaceuticals SpA is a clinical stage biopharmaceutical company focused on the discovery and development of small molecule drugs for the treatment of central nervous system (CNS) diseases. Ou...

Aurinia Pharmaceuticals Inc.

Aurinia is a clinical stage pharmaceutical company focused on the global nephrology market. It is currently enrolling patients in its Phase 2b clinical trial to evaluate the effic...

Lifecode, Inc.

Lifecode is a specialized CLIA certified clinical laboratory focused on the genetic basis of human disease. With an initial focus on oncology, we are committed to improving the li...

ProteoTech Inc.

ProteoTech is a privately-held, drug development company that utilizes its amyloid expertise to discover and develop new drugs for treating misfolded protein disorders and amyloid...

Aileron Therapeutics

Aileron Therapeutics is a biopharmaceutical company leading the development of a new therapeutic modality and class of drugs called Stapled Peptides. Published research on Stapled...

Clinical Trials [1328 Associated Clinical Trials listed on BioPortfolio]

Age-Related Changes in Body Composition

Background: - Advancing age is associated with greater risk of heart disease. High blood pressure and hardening of the arteries also have more complications with age. Studies suggest that...

Pilot Study Assessing the Effects of PXT00864 in Patients With Mild Alzheimer Disease (AD)

The purpose of this study is to assess the safety and efficacy on cognitive impairment and functioning of several doses of PXT00864 (new fixed combination of acamprosate and baclofen at lo...

Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus Placebo

To test the idea that solanezumab will slow the cognitive and functional decline of Alzheimer's Disease (AD) as compared with placebo in participants with mild AD.

Effects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's Disease

This 24-week study will examine the sensitivity of functional MRI to detect brain changes caused by donepezil HCL (a cholinesterase inhibitor) in healthy older adults at genetic risk for A...

Micro-Particle Curcumin for the Treatment of Chronic Kidney Disease

An investigator initiated pilot trial: two arm, double blind, placebo controlled, randomized, parallel group of approximately 750 patients with chronic kidney disease, and who have evidenc...

Assessing Neurocognitive Effects of Gluten Exposure

Many patients with celiac disease complain of neurocognitive symptoms such as mental confusion, grogginess, difficulty with concentration and forgetfulness after exposure to gluten. Howev...

A Study to Evaluate the Effectiveness and Safety of CNTO6785 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

The purpose of the study is to evaluate the effect of CNTO6785 compared with placebo in participants with moderate to severe Chronic Obstructive Pulmonary Disease.

A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study)

This randomized, double-blind, placebo-controlled study will evaluate the potential of aleglitazar to reduce the risk of end stage renal disease and cardiovascular mortality in patients wi...

Efficacy of Isradipine in Early Parkinson Disease

The purpose of the study is to determine whether treatment with isradipine is effective in slowing the progression of Parkinson disease disability.

Safety, Tolerability, and Pharmacodynamic Profile of Oral 2101 in Secondary Raynaud's Disease

To investigate the severity of secondary Raynaud's disease-related attacks during the 14 days 2101 dosing period.

Medical and Biotech [MESH] Definitions

Animate or inanimate sources which normally harbor disease-causing organisms and thus serve as potential sources of disease outbreaks. Reservoirs are distinguished from vectors (DISEASE VECTORS) and carriers, which are agents of disease transmission rather than continuing sources of potential disease outbreaks.

Analyses for a specific enzyme activity, or of the level of a specific enzyme that is used to assess health and disease risk, for early detection of disease or disease prediction, diagnosis, and change in disease status.

The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.

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