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Eye disease - Biotech, Pharma and Life Science Channel

09:11 EDT 24th April 2014 | BioPortfolio

PubMed Articles [11068 Associated PubMed Articles listed on BioPortfolio]

Preventing and controlling zoonotic tuberculosis: a One Health approach.

The expression One Health refers to the unified human and veterinary approach to zoonoses, an approach that used to be identified with Medicine throughout the 20th Century. Zoonotic tuberculosis (TB),...

Positioning therapy for Crohn's disease.

The therapy of Crohn's disease is constantly evolving. It is widely recognized that clinical assessment does not stage disease activity accurately and that endoscopic healing is associated with improv...

Aspirin Desensitization: Useful Treatment for Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) in Aspirin-Exacerbated Respiratory Disease (AERD)?

Aspirin intolerance syndrome is due to disturbances in the arachidonic acid metabolism implicating both the lipoxygenase and cyclooxygenase pathways. This results in imbalances of eicosanoid, leukotri...

Chondrosarcoma of the proximal humerus secondary to ollier disease: an 8-year follow-up of successful resection of the tumor with endoprosthetic replacement of the proximal humerus.

We present a 25-year-old male patient with a diagnosis of multiple enchondromatosis, who developed chondrosarcoma on the proximal humerus of the right upper limb. The patient had the pre-existing lesi...

Modulation of microrna expression by volatile organic compounds in mouse lung.

Volatile organic compounds (VOCs) are one of main pollutants indoors. Exposure to VOCs is associated with cancer, asthma disease, and multiple chemical allergies. Despite the adverse health effects of...

The use of targeted temperature management for elevated intracranial pressure.

The use of hypothermia for treatment of intracranial hypertension is controversial, despite no other medical therapy demonstrating consistent improvements in morbidity or mortality. Much of this may b...

Understanding essential tremor: progress on the biological front.

For many years, little was written about the underlying biology of ET, despite its high prevalence. Discussions of disease mechanisms were dominated by a focus on tremor physiology. The traditional mo...

Epilepsy: old syndromes, new genes.

Next-generation sequencing technologies have tremendously increased the speed of gene discovery in monogenic epilepsies, enabling us to identify a genetic cause in an increasing proportion of patients...

Metabolomics approach in allergic and rheumatic diseases.

Metabolomics is the analysis of the concentration profiles of low molecular weight compounds present in biological fluids. Metabolites are nonpeptide molecules representing the end products of cellula...

Helminth/Parasite treatment of multiple sclerosis.

Epidemiological studies suggest that autoimmune diseases, such as multiple sclerosis (MS), are less frequent in individuals who are helminth carriers. This observation has been tested in murine models...

News Articles [7535 Associated News Articles listed on BioPortfolio]

Celgene Acquires Late-Stage Product for Crohn’s Disease and Other Gastrointestinal Disorders

- GED-0301 is a First-in-Class, Oral Antisense Drug Targeting Smad7 mRNA - Phase III Program for Crohn’s Disease Targeted to Begin by Year-End 2014 Ce...

FDA backs Janssen’s Sylvant for rare disease

The US Food and Drug Administration yesterday approved Johnson & Johnson subsidiary Janssen Biotech’s Sylvant (siltuximab) to treat patients with multicentric Castleman’s disease (MCD), a rare dis...

Catalyst starts process to offer Firdapse at no cost to LEMS patients in US

US-based Catalyst Pharmaceutical Partners has initiated the process necessary to establish an expanded access program (EAP) to make available its investigational potassium channel inhibitor, Firdapse...

HemoShear, Medivir enter research and development collaboration

HemoShear, a US-based human disease biology firm, has entered into research collaboration with Medivir, a Swedish pharmaceutical firm focused on infectious diseases.

Medivation, OncoFusion sign license deal for new bromodomain proteins in oncology

US-based biopharmaceutical firm Medivation and OncoFusion Therapeutics have entered into a research and license agreement for certain compounds targeting Bromodomain and Extra-Terminal (BET) proteins...

Why do some people with Alzheimer's disease die without cognitive impairment?

Since the time of Dr. Alois Alzheimer himself, two proteins (beta-amyloid (Aβ) and tau) have become tantamount to Alzheimer's disease (AD). But a Mayo Clinic study challenges the perception that thes...

Anne Geddes Unveils Inspirational Book Highlighting the Courage and Promise of Meningococcal Disease Survivors in Honor of World Meningitis Day

NEW YORK, April 24, 2014 /PRNewswire/ -- World-renowned photographer and global advocate for children, Anne Geddes, announces the release of her new book, Protecting Our Tomor...

Treatment for deadly yeast disease reduced to three days

(Medical Xpress)—Initial treatment for a brain infection caused by fungus could now be treated in three days, rather than two weeks, due to study by University of Liverpool scientists.

Fibroblasts could offer alternative to heart transplants

(Medical Xpress)—Fibroblasts, cells long thought to be boring and irrelevant, could offer an alternative to heart transplants for patients with heart disease.

Orion BioNetworks Hosts Rancho BioSciences Webinar May 6th Entitled “The Role of Gut Microbiome on MS Risk and Progression”

There are intriguing suggestions that the microbiome can have profound effects on inflammatory and immune responses system wide. In the seminar Rancho will explore the interaction of the microbiome wi...

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Companies [256 Associated Companies listed on BioPortfolio]

Batten Disease Support and Research Association

Cardax, Inc.

Cardax is a development stage life sciences company that devotes substantially all of its efforts to developing nutraceutical and pharmaceutical products that provide the anti-inf...

FORUM Pharmaceuticals Inc.

FORUM Pharmaceuticals Inc. and its subsidiaries (“FORUM Pharmaceuticals” or “FORUM”) are dedicated to developing groundbreaking medicines in support of all tho...

Aerpio Therapeutics, Inc.

Aerpio Therapeutics, Inc. is a clinical‐stage biopharmaceutical company focused on advancing innovative therapies for the treatment of diabetic eye disease and inflammatory b...

Intelligent Medical Objects

IMO provides the most widely accepted medical terminology solution for the development, management, and licensing of medical vocabularies and software applications at healthcare o...

Allegro Diagnostics Corp.

Allegro Diagnostics’ molecular testing platform utilizes gene expression of normal epithelial cells in the respiratory tract to detect early signs of lung cancer and diseases...

Catabasis Pharmaceuticals Inc.

Catabasis is a clinical-stage company dedicated to the discovery and development of innovative medicines to treat inflammatory and metabolic diseases. The company's drug developme...

Premier Biomedical, Inc.

Premier Biomedical, Inc. is a research-based company that intends to discover and develop medical treatments for humans, specifically targeting the treatment of Alzheimer's Diseas...

International Union Against Tuberculosis and Lung Disease

Exosome Diagnostics, Inc.

Exosome Diagnostics is a developer of proprietary molecular diagnostic tests with applications in oncology and metabolic disease. The company's core technology is based on the discovery that circulat...

Clinical Trials [1270 Associated Clinical Trials listed on BioPortfolio]

Dose Escalation of Hypofractionated Radiation Therapy in Patients With Metastatic Cancer

Patients with metastatic cancer are generally treated with chemotherapy, which has improved median survival compared to best supportive care. Despite this, patients continue to have persi...

A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)

The main purpose of the study is to evaluate the efficacy and safety of the study drug known as prasugrel for the reduction of Vaso-Occlusive Crisis events in pediatric participants with s...

Adipose Derived Cells for Chronic Obstructive Pulmonary Disease

The intent of this clinical study is to answer the questions: 1) Is the proposed treatment safe and 2) Is treatment effective in improving the disease pathology of patients with diagnosed...

FG-4592 (ASP1517) in the Treatment of Anemia in Chronic Kidney Disease Patients Not Requiring Dialysis

This study is conducted to treat anemia in patients with chronic kidney disease. Anemia is a reduced number of red blood cells or hemoglobin. Hemoglobin is important for the transport of o...

Trial of Superiority of Stereotactic Body Radiation Therapy in Patients With Breast Cancer

The previous reported phase I study allows us to prospectively define the optimal total dose in different metastatic locations (88). However, several questions are still unanswered such as...

Impact on Reducing the Incidence of Low Serum Calcium by Providing Educational Materials on the Need to Take Daily Supplemental Calcium and Vitamin D to Patients With Paget's Disease Treated With Reclast®

This study will evaluate the impact of investigator and patient education and educational materials to foster calcium and vitamin D supplementation to mitigate the potential for hypocalcem...

A Randomised Placebo Controlled Study of OXN PR for Severe Parkinson's Disease Associated Pain

To demonstrate superiority of OXN PR compared to placebo with respect to analgesic efficacy in subjects with chronic severe pain associated with Parkinson's disease (PD), as assessed by av...

Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of,...

Open-label Trial of Leukine in Active Crohn's Disease

The purpose of this study is to establish a safety profile sargramostim administered in 8 week cycles to adult patients with active Crohn's disease.

Effect of EGb 761® on Patients With Mild to Moderate Alzheimer's Disease

The aim of this study is to measure the effect of EGb 761® versus placebo on the ratio of the isoform of the protein precursor of beta amyloid platelets, in patients with mild to moderate...

Medical and Biotech [MESH] Definitions

Animate or inanimate sources which normally harbor disease-causing organisms and thus serve as potential sources of disease outbreaks. Reservoirs are distinguished from vectors (DISEASE VECTORS) and carriers, which are agents of disease transmission rather than continuing sources of potential disease outbreaks.

Analyses for a specific enzyme activity, or of the level of a specific enzyme that is used to assess health and disease risk, for early detection of disease or disease prediction, diagnosis, and change in disease status.

The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.

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