Eye disease - Biotech, Pharma and Life Science Channel

11:27 EDT 7th July 2015 | BioPortfolio

PubMed Articles [14866 Associated PubMed Articles listed on BioPortfolio]

Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer's disease.

PET radiopharmaceuticals capable of imaging β-amyloid (Aβ) plaque burden in the brain could offer highly valuable diagnostic tools for clinical studies of Alzheimer's disease. To further supplement ...

Immune Tolerance Induction against Experimental Autoimmune Encephalomyelitis (EAE) Using A New PLP-B7AP Conjugate that Simultaneously Targets B7/CD28 Costimulatory Signal and TCR/MHC-II Signal.

Most of the current therapies used in the treatment of multiple sclerosis (MS) are either ineffective or have adverse side effects. As such, there is a need to develop better therapies that specifical...

Update in primary pulmonary lymphomas.

Despite the fact that primary pulmonary lymphoma (PPL) is a rare lung tumour, significant advances addressing clinical features, histological diagnosis, prognostic criteria and therapeutic management ...

Interstitial lung disease related to smoking: imaging considerations.

To discuss the imaging of interstitial lung disease believed to be caused by smoking.

An Evidence-Based Review of Alternating Electric Fields Therapy for Malignant Gliomas.

Glioblastoma is a deadly disease and even aggressive neurosurgical resection followed by radiation and chemotherapy only extends patient survival to a median of 1.5 years. The challenge in treating t...

Secondary Adult Acute Myeloid Leukemia: a Review of Our Evolving Understanding of a Complex Disease Process.

Secondary AML (s-AML) encompasses AML evolving from myelodysplasia (AML-MDS) and treatment-related AML (t-AML) after exposure to chemotherapy, radiation, or environmental toxins. S-AML has traditional...

Managing Disease and Therapy-Related Complications in Patients with Central Nervous System Tumors.

Treating patients with brain tumors can be divided into tumor-directed therapies, the management of tumor-related symptoms and complications and the psychosocial aspect of patient care. In this review...

An age-structured model for the coupled dynamics of HIV and HSV-2.

Evidence suggests a strong correlation between the prevalence of HSV-2 (genital herpes) and the perseverance of the HIV epidemic. HSV-2 is an incurable viral infection, characterized by periodic react...

Clinical pearls in vascular medicine and anticoagulation.

Clinical pearls in palliative medicine.

News Articles [6281 Associated News Articles listed on BioPortfolio]

Liberian President to Keynote Gala for Global Health

President Ellen Johnson Sirleaf has led Liberia through the recent Ebola outbreak The Center for Infectious Disease Research announced today that President Ellen Johnso...

Summit Therapeutics adds Europe to patent list for key compound

Summit Therapeutics (LON:SUMM, NASDAQ:SMMT) has been granted a patent for its  small molecule utrophin modulator SMT C1100 by the European Patent Office.   The patent protects SMT C1100 ...

Discovery brings MRC scientists one step closer to finding malaria cure

Scientists have identified a key protein that if targeted prevents the malaria parasite's survival, a discovery that could pave the way to a cure for the disease.

MicroRNAs in platelet function and cardiovascular disease

Despite being anucleate, platelets contain RNA transcripts, including microRNAs, which are involved in regulating platelet function and which can also be transferred to other vascular cells. In this R...

Cholera kills 32 in South Sudan, education key to stemming outbreak - U.N.

LONDON, July 7 (Thomson Reuters Foundation) - A cholera outbreak in war-torn South Sudan has killed at least 32 people, a fifth of them children under five, and schools have a major role to play in st...

PV-10 shows potential in hepatocellular carcinoma and metastatic liver disease

by ecancer reporter Janet Fricker Two patients – one with hepatocellular carcinoma (HCC) and one with colorectal cancer (CRC) metastatic to the liver - had non-existent liver cancer at more than 40...

Alexion's Strensiq approved in Japan for ultra-rare metabolic disease

Japan’s Ministry of Health, Labor and Welfare has approved the New Drug Application from US pharma…

Rare Disease United Foundation Brings Art of Medicine to Medical Schools

PROVIDENCE, R.I., July 7, 2015 /PRNewswire-USNewswire/ -- The Rare Disease United Foundation created the Beyond the Diagnosis Art Exhibit to encourage the medical community to look beyond the diagnosi...

Combination of diabetes and heart disease substantially reduces life expectancy

Life expectancy for people with a history of both cardiovascular disease and diabetes is substantially lower than for people with just one condition or no disease, a new study harnessing the power of ...

Cholera kills 32 in South Sudan, education key to stemming outbreak: U.N.

By Kieran Guilbert LONDON (Thomson Reuters Foundation) - A cholera outbreak in war-torn South Sudan has killed at least 32 people, a fifth of them children under five, and schools have a major role to...

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Companies [302 Associated Companies listed on BioPortfolio]

Seres Therapeutics, Inc.

Seres Therapeutics, Inc. is a leading microbiome therapeutics platform company developing a novel class of biological drugs that are designed to treat disease by restoring the fun...

Center for Infectious Disease Research

Center for Infectious Disease Research is the largest independent, non-profit organization in the U.S. focused solely on infectious disease research. Our mission is to make transf...

The Feinstein Institute for Medical Research

Headquartered in Manhasset, NY, The Feinstein Institute for Medical Research is home to international scientific leaders in many areas including Parkinson's disease, Alzhei...

Global Genes

Global Genes is a non-profit organization that operates as one of the leading rare disease patient advocacy groups in the world. Global Genes promotes the needs of the Rare Diseas...

EBR Systems, Inc.

EBR Systems is dedicated to superior treatment of cardiac rhythm disease by providing more physiologically effective stimulation through wireless endocardial pacing. The companyâ...

Health Recovery Solutions

Health Recovery Solutions, a New York City based telehealth provider, supplies the nation’s leading medical centers and home health agencies with disease-specific platforms f...

Kedrion Biopharma Inc.

Kedrion is an international company that collects and fractionates blood plasma to produce and distribute plasma-derived therapeutic products for use in treating and preventing se...

Newron Pharmaceuticals S.p.A.

Newron (SIX: NWRN) is a biopharmaceutical company focused on the development of novel therapies for patients with diseases of the central nervous system (CNS) and pain. The Compan...

InterVene Inc.

InterVene Inc. has developed the first non-implantable, catheter-based, vein valve creation therapy. The product is designed to treat chronic venous insufficiency (CVI) in the dee...

AqueSys, Inc.

AqueSys, Inc. is a privately-held company headquartered in Irvine, California. The company is focused on the research, development, manufacturing and distribution of implantable devices used to treat ...

Clinical Trials [1388 Associated Clinical Trials listed on BioPortfolio]

Dexlansoprazole MR in Nonerosive Reflux Disease

This study aim is to compare the efficacy of Dexlansoprazole MR intake before and after breakfast in patients with nonerosive reflux disease.

Protocol: Balance Training in Parkinson's Disease

Postural instability is a particularly incapacitating disorder, where loss of motor independence by Parkinson´s Disease (PD) patients marks a significant stage of disease onset. Evidence ...

Targeted Therapy With Gefitinib in Patients With USP8-mutated Cushing's Disease

The USP8 gene and its downstream target, epidermal growth factor receptor (EGFR), is a potential therapeutic target of Cushing disease. The EGFR inhibitor, Gefitinib, has been shown to re...

A Study to Evaluate the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease

The purpose of this study is to determine whether ticagrelor is effective in reducing the number of days of pain, intensity of pain, and reducing the use of analgesics due to sickle cell d...

INfusion VErsus STimulation in Parkinson's Disease

Both Continuous intrajejunal Levodopa Infusion (CLI) and Deep Brain Stimulation (DBS) are accepted therapies for the treatment of advanced Parkinson's disease (PD). To date, no comparative...

VX15/2503 Treatment for Huntington Disease

The purpose of this study is to evaluate the safety, tolerability, PK, and efficacy of VX15/2503 in subjects with late prodromal and early manifest Huntington disease.

Ayurvedic Management of Chronic Kidney Disease

The purpose of this study is to determine the effect of multi-dimentional ayurvedic treatment in the patients of various types of chronic kidney disease.

Telehealth Cognitive Behavioral Therapy for Depression in Parkinson's Disease (PD)

The purpose of this study is to test a psychotherapeutic intervention aimed at treating depression in Veterans with Parkinson's Disease (PD).

Evaluating the Influence of Single Task vs. Dual Task Exercise on Rehabilitation in Parkinson's Disease

The purpose of this study is to evaluate the underlying mechanism and influence of single task vs. dual task exercise on rehabilitation in Parkinson's disease. The upcoming exercise interv...

Percutaneous Aponeurotomy in the Treatment of Dupuytren's Disease

The efficiency of percutaneous aponeurotomy in the treatment of Dupyutrens disease is well known. However, the duration of the clinical improvement after aponeurotomy is not well known. ...

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Medical and Biotech [MESH] Definitions

Animate or inanimate sources which normally harbor disease-causing organisms and thus serve as potential sources of disease outbreaks. Reservoirs are distinguished from vectors (DISEASE VECTORS) and carriers, which are agents of disease transmission rather than continuing sources of potential disease outbreaks.

Analyses for a specific enzyme activity, or of the level of a specific enzyme that is used to assess health and disease risk, for early detection of disease or disease prediction, diagnosis, and change in disease status.

The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.


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