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Fatal Insomnia - Biotech, Pharma and Life Science Channel

10:01 EDT 1st October 2016 | BioPortfolio

PubMed Articles [845 Associated PubMed Articles listed on BioPortfolio]

Fatal Case of West Nile Neuroinvasive Disease in Bulgaria.

In Vivo Magnetic Resonance Imaging and Microwave Thermotherapy of Cancer Using Novel Chitosan Microcapsules.

Herein, we develop a novel integrated strategy for the preparation of theranostic chitosan microcapsules by encapsulating ion liquids (ILs) and Fe3O4 nanoparticles. The as-prepared chitosan/Fe3O4@IL m...

Cellular transplant therapies for globoid cell leukodystrophy: Preclinical and clinical observations.

Globoid cell leukodystrophy (GLD) is a progressive neurodegenerative disorder caused by the deficiency of galactocerebrosidase (GALC), resulting in accumulation of toxic metabolites in neural tissues....

Can psychosine and galactocerebrosidase activity predict early-infantile Krabbe's disease presymptomatically?

Krabbe's disease (KD) is a fatal neurodegenerative disorder, with the early-infantile form (EIKD) defined by onset of symptoms before age 6 months. Early and highly accurate identification of EIKD is ...

A microglial hypothesis of globoid cell leukodystrophy pathology.

Globoid cell leukodystrophy (GLD), also known as Krabbe's disease, is a fatal demyelinating disease accompanied by the formation of giant, multinucleated cells called globoid cells. Previously believe...

Clinical, electrophysiological, and biochemical markers of peripheral and central nervous system disease in canine globoid cell leukodystrophy (Krabbe's disease).

Globoid cell leukodystrophy (GLD), or Krabbe's disease, is a debilitating and always fatal pediatric neurodegenerative disease caused by a mutation in the gene encoding the hydrolytic enzyme galactosy...

Sleep Duration and Diabetes Risk: Population Trends and Potential Mechanisms.

Sleep is important for regulating many physiologic functions that relate to metabolism. Because of this, there is substantial evidence to suggest that sleep habits and sleep disorders are related to d...

Diagnostic biomarkers in venous thromboembolic disease.

Venous thromboembolism (VTE) is a common disease with serious, often fatal sequelae. The optimal strategy for diagnosis of VTE remains unclear, although considerable progress has been made in this are...

Educational report: A case of lacrimal sac rhinosporidiosis.

This article reports a presentation of lacrimal sac rhinosporidiosis and informs the reader of this uncommon but important diagnosis. A 36-year-old man from Pakistan presented with a 3-month history o...

News Stories of Intimate Partner Violence: An Experimental Examination of Participant Sex, Perpetrator Sex, and Violence Severity on Seriousness, Sympathy, and Punishment Preferences.

This study experimentally examines the effects of participant sex, perpetrator sex, and severity of violence on perceptions of intimate partner violence (IPV) seriousness, sympathy toward the victim, ...

News Articles [662 Associated News Articles listed on BioPortfolio]

Graceleigh, Inc. Recalls Sammy’s Milk Baby Food Because of Possible Health Risk

Graceleigh, Inc. d/b/a Sammy’s Milk is recalling all lots of Sammy’s Milk Baby Food because of possible presence of Cronobacter, a bacteria that can cause severe and sometimes fatal blood infectio...

Fatal Police Shooting Of Mentally Ill Man Highlights Issue Plaguing The Country

People with severe mental illness are 16 times more likely to be killed by police. States across the U.S. are trying to address the problem, but police officials say part of the problem is the decay o...

Drug Overdose Deaths Drive Increase in Number of Organ Donations: One Family’s Story of Hope from Despair

(ABC News) – In recent years, so many people have died as a result of the nation’s opioid epidemic that it has caused the number of organ donations from fatal overdose victims to skyrocket ...

Academy of Integrative Pain Management Past President's Response to the Surgeon General's Opioid Pledge: First Come to Terms with Chronic Pain, then with Patient Access to Covered Non-Pharmacologic Treatments

SONORA, Calif., Sept. 29, 2016 /PRNewswire/ -- Last week, the Academy of Integrative Pain Management (formerly the American Academy of Pain Management) held its 27th Annual Meeting, educating attendee...

Bullying, Asthma, and Food Allergy: What Can Be Done?

MIAMI, Sept. 29, 2016 /PRNewswire/ -- Victims of bullying feel powerless and vulnerable, which often produces devastating psychological consequences (severe depression or even suicide). Early identifi...

Long-term study shows less frequent and severe pancreatitis following gene therapy for LPLD

Up to 6 years after receiving a single treatment with the gene therapy product lipoprotein lipase (LPL), patients with the debilitating genetic disease LPL deficiency (LPLD) had about 50% fewer episod...

American Cheese, Sidewalks and Chairs Have a Connection that may Surprise You

SOURCE: Bloomberg DESCRIPTION:Originally posted by the Washington Post. The Johns Hopkins Bloomberg School of Public Health turns 100 this year. The school came to life during a time when women freque...

Fibromyalgia Product Merits Top Rating from TopConsumerReviews.com

Fibro Freedom, a leading product for relieving the symptoms of Fibromyalgia, receives the highest ranking available from TopConsumerReviews.com. Overland Park, KS (PRWEB) September 29, 2016 TopConsum...

New England Journal of Medicine Publishes Study on Zika Genomic Sequence Identification by IDbyDNA

SAN FRANCISCO, Sept. 28, 2016 /PRNewswire/ -- IDbyDNA, a precision medicine company focused on metagenomic approaches for infectious disease identification, today announced publication results in...

Gilead donates $20 million to enhance access to treatment for often fatal neglected tropical disease

Gilead Sciences has entered into a partnership with the World Health Organization to provide $20 million…

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Companies [17 Associated Companies listed on BioPortfolio]

CurePSP

CurePSP is the leading nonprofit advocacy organization focused on prime of life neurodegenerative diseases – a spectrum of fatal brain disorders that often strike during a pe...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the ...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Clinical Trials [514 Associated Clinical Trials listed on BioPortfolio]

STATE Trial: SusTained Attention Training to Enhance Sleep

This study is a validation study to document the acceptability of the Tonic and Phasic Alertness Training (TAPAT) training program in older adults with chronic late-life insomnia. The goal...

Development of a Polyphenol-rich Dietary Preparation for Treating Veterans With Gulf War Illness

Gulf War Illness (GWI) is a multi-symptom disorder that is characterized by complex traits such as fatigue, headaches, joint pain, insomnia, and memory problems. With no treatment for GWI ...

Aprepitant Without Steroid in Preventing Chemotherapy-induced Nausea and Vomiting in Patients With Colorectal Cancer

Addition of aprepitant, an NK1 receptor antagonist to a 5-HT3 receptor antagonist and dexamethasone regimen was shown to be effective for prevention of chemotherapy-induced nausea and vomi...

The KHENERGY Study

Mitochondrial Diseases are rare, progressive, multi-system, often-early fatal disorders affecting both children and adults. KH176 is a novel chemical entity currently under development for...

Identification of New Genetic Markers of Risk of Venous Thromboembolism Recurrence by Analyzing Whole Genome

Venous thromboembolism (VTE) is a common and potentially fatal disease. It is considered a chronic disease with a recurrence rate of 30% at 10 years. Reduce the risk of recurrence is a se...

Colchicine for Prevention of Vascular Inflammation in Non-cardio Embolic Stroke

This study evaluates the use of Colchicine in adults over 40 years of age who have suffered an ischaemic stroke or transient ischaemic attack NOT caused by cardiac embolism or other define...

Development and Evaluation of a Sleep-coaching Program

In the present study, a 4-week sleep coaching program is developed and evaluated in members of the German armed Forces. The aim of the program is to provide an efficient tool to prevent sl...

A Pragmatic Pilot Study of Cognitive Behavioural Therapy for Insomnia Among People Living With HIV

Insomnia is a problem for approximately 75% of people living with HIV, which is much higher than the 6% to 10% of people with insomnia in the general population. It is currently unknown wh...

DEpth of EPinephrine Delivery With Auto-injectors Devices

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. Although there are several causes of fatal anaphylaxis, food allergy is one of the most common. Epine...

Internet-based Cognitive Behavior Therapy for Insomnia for Parents Who Have Lost a Child

The purpose of this project is to evaluate an Internet-based Cognitive Behavioral Therapy (ICBT) for bereaved parents with insomnia. Participants are randomized to either a therapist guide...

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Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

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