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Fatal Insomnia - Biotech, Pharma and Life Science Channel

03:38 EDT 21st April 2014 | BioPortfolio

PubMed Articles [638 Associated PubMed Articles listed on BioPortfolio]

An Efficient RFID Authentication Protocol to Enhance Patient Medication Safety Using Elliptic Curve Cryptography.

Medication errors are very dangerous even fatal since it could cause serious even fatal harm to patients. In order to reduce medication errors, automated patient medication systems using the Radio Fre...

Chemotherapy and QT Prolongation: Overview With Clinical Perspective.

Cardiotoxic adverse events are of concern to physicians treating cancer patients; they are encountered with a variety of agents. Cardiac events may delay the approval of new drugs or impose burdensome...

Human prion diseases and the risk of their transmission during anatomical dissection.

Prion diseases (or transmissible spongiform encephalopathies) are a unique group of fatal progressive neurodegenerative diseases of the central nervous system. The infectious agent is hypothesized to...

Novel adenosine deaminase 2 mutations in a child with a fatal vasculopathy.

Adenosine deaminase 2 (ADA2) deficiency due to CECR1 mutations is a recently defined disorder that involves systemic inflammation and vasculopathy often associated with polyarteritis nodosa. We report...

Necrotizing fasciitis: a review.

Necrotizing fasciitis is a rare, fatal bacterial infection associated with a high morbidity in humans (25-40%) that is frequently underdiagnosed in veterinary patients. Rapid diagnosis of the disease...

Management of pseudoaneurysm of internal carotid artery in post-irradiated nasopharyngeal carcinoma patients.

Objective: Massive epistaxis due to ruptured pseudoaneurysm of internal carotid artery (ICA) is an often-fatal complication of radiation treatment for patients with nasopharyngeal carcinoma. We would...

Retinal microvascular damage and vasogenic edema produced by Clostridium perfringens type D epsilon toxin in rats.

When the brain is exposed to large circulating levels of Clostridium perfringens type D epsilon toxin (EXT), microvascular damage with resulting severe, generalized, vasogenic edema seems to be princi...

What influences youth to operate all-terrain vehicles safely?

The operation of all-terrain vehicles (ATVs) by youth has contributed to the incidence of serious and fatal injuries among children. This study explored factors related to the frequency with which you...

A prospective study on distribution of eschar in patients suspected of scrub typhus.

Scrub typhus is an acute febrile illness caused by a tick bite infected with the bacteria Orientia tsutsugamushi. The clinical diagnosis is difficult as the symptoms are similar to other febrile illne...

Raoultella planticola-associated cholangitis and sepsis: a case report and literature review.

Raoultella planticola is a Gram-negative anaerobic bacterium and a rare cause of human infection. Only 12 cases of clinically relevant human infections (two fatal) have been reported.CASE REPORT: A 70...

News Articles [597 Associated News Articles listed on BioPortfolio]

The One-Minute Cure Review | Introduces How To Improve The Health – Vinaf.com

The One-Minute Cure is a new program developed by Madison Cavanaugh, who promises to teach people how to improve their overall health. An overview on the website Vinaf.com shows if the program is good...

Benzodiazepines may contribute to respiratory problems in people with COPD

A group of drugs commonly prescribed for insomnia, anxiety and breathing issues "significantly increase the risk" that older people with chronic obstructive pulmonary disease, or COPD, need to visit a...

Insomnia May Increase Stroke Risk

Young adults with insomnia may be up to eight times more likely to suffer a stroke than those who have no trouble sleeping, according to a study by researchers in Taiwan. They compared health records...

Vietnam battles fatal measles outbreak

Vietnam is scrambling to contain a deadly outbreak of measles that has killed more than 100 people, mostly young children, and infected thousands more this year, the government said Friday.

Viagra Associated with Increased Risk of Melanoma

Men who take by Viagra (sildenafil) are 84 percent more likely to develop melanoma than men who do not, according to the results of a study published in JAMA Internal Medicine. Melanoma is a potential...

Gene variant raises risk for aortic tear, rupture

The significance of a genetic variant that substantially increases the risk of a frequently fatal thoracic aortic dissection or full rupture has been confirmed by researchers. Thoracic aortic aneurysm...

Gene variant raises risk for aortic tear and rupture

Researchers from Yale School of Medicine and Celera Diagnostics have confirmed the significance of a genetic variant that substantially increases the risk of a frequently fatal thoracic aortic dissect...

Pernix Establishes New Corporate Headquarters

Pernix Therapeutics Holdings, Inc. (“Pernix” or the “Company”) (NASDAQ MKT: PTX), a specialty pharmaceutical company, today announced it has signed a lease for new corpora...

Measles Treatment Excels In Antiviral Drug Tests

Developed by scientists in the US and Germany, a new antiviral drug could reduce the sickness component of measles and stop the condition's spread from person-to-person. Based at Georgia State Univers...

Special supplement explores the causes of distracted driving among teens

Motor vehicle crashes rank as the leading cause of teen deaths and in 2008, 16% of all distraction-related fatal automobile crashes involved drivers under 20 years of age.

Events [0 Results]

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Companies [14 Associated Companies listed on BioPortfolio]

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Isabel Healthcare Inc.

Isabel Healthcare Inc. was founded in 2000 by Jason Maude and is named after Maude’s daughter who almost died after a potentially fatal illness was not recognized. Isabel Hea...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the...

Somaxon Pharmaceuticals, Inc.

Headquartered in San Diego, CA, Somaxon Pharmaceuticals, Inc. is a specialty pharmaceutical company focused on the in-licensing, development and commercialization of proprietary b...

Clinical Trials [348 Associated Clinical Trials listed on BioPortfolio]

Treating Sleep Problems in VA Adult Day Health Care

The Veterans Millennium Health Care and Benefits Act (Millennium Act) of 1999 mandated the Department of Veterans Affairs (VA) to provide non-institutional long-term care to veterans. Adul...

Chemotherapy Treatment for Children With Intraocular Germ-Line Retinoblastoma

Retinoblastoma is an unusual cancer of early childhood involving tumor is both eyes or, in certain circumstances, one eye only. This condition is the result of an abnormal gene which makes...

Randomized Clinical Trial of 4RIF Vs. 9INH for the Treatment of Latent TB

Although effective medications to treat and even prevent Tuberculosis (TB) have been available for over 40 years, TB remains the most important infectious cause of mortality among adults i...

Use of Probiotics to Prevent Cholangitis in Children With Biliary Atresia After the Kasai Portoenterostomy

Abstract Biliary atresia (BA) is an idiopathic, progressive, and fatal disease if untreated. Since Kasai first introduced the operation for BA in 1959, there have been encouraging results...

Failed Retrieval of Inferior Vena Cava (IVC) Filters: Long-Term Outcomes

The inferior vena cava (IVC) is a large vein that enters the bottom part of the heart. Venous blood from the lower portion of the body drains into the IVC. The IVC then returns blood back...

Safety and Efficacy Study of Antisense Oligonucleotides in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD), a fatal muscle degenerative disorder, arises from mutations in the dystrophin gene. Antisense therapy with the use of antisense oligonucleotides (AON) ha...

Effects of Cognitive-Behavioral Therapy on Sleep Disturbance in Peritoneal Dialysis Patients

Sleep disturbance is prevalent in chronic dialysis patients and there is a negative correlation between the quality of life and overall survival and sleep disturbance in them. Cognitive-be...

Dexamethasone Study: Impact on Quality of Life of Continuing Dexamethasone Following Emetogenic Chemotherapy

Background: Dexamethasone is a steroid, which is often given into the vein before chemotherapy to help control acute nausea and vomiting. It can also be given as an oral tablet for patient...

Cognitive Behavioral Therapy for Insomnia in Chronic Pain Patients

This study of cognitive behavioral therapy for insomnia in chronic pain patients is a randomized, controlled clinical trial of parallel groups with three and six months follow up.

Phase 3 Trial for AML Patients in CR2 Comparing 8Gy TBI /Fludarabine to Conditioning With TBI 12Gy/Cyclophosphamide

For patients with acute myeloid leukemia (AML), allogeneic hematopoetic stem cell transplantation (HSCT) is one of the most potent treatment options currently available. In order to overco...

Videos

Dying To Sleep - Documentary

This documentary deals with a very rare and unusual prion disease called Fatal Familial Insomnia or FFI for short. FFI is a prion disease that targets the th...

Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

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