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Fatal Insomnia - Biotech, Pharma and Life Science Channel

18:41 EST 21st February 2017 | BioPortfolio

PubMed Articles [829 Associated PubMed Articles listed on BioPortfolio]

Lethal Angiostrongylus vasorum infection in a Hungarian dog.

During post-mortem examination of lungs and heart of a 7-month-old female French bulldog, 158 worms were collected from the lung vessels and they proved Angiostrongylus vasorum by their morphological ...

Report of fatal mixed infection with Cryptosporidium parvum and Giardia intestinalis in neonatal calves.

In the production and management of beef and dairy cattle, controlling diarrhea is one of the important concerns. Pathogenic agents of the disease, protozoan parasites including Cryptosporidium spp., ...

Concurrent chemotherapy alone versus irreversible electroporation followed by chemotherapy on survival in patients with locally advanced pancreatic cancer.

Pancreatic adenocarcinoma is one of the most fatal cancers, characterized by aggressive tumor growth and a short patient survival time between diagnosis and death. Safe and effective treatment options...

Assessing the potential function of ADAR1 in virus-associated sepsis.

Sepsis syndrome is a common and frequently fatal clinical condition. It is defined by the presence of both infection and an uncontrolled systemic inflammatory response. It represents a major, although...

Paraneoplastic pemphigus associated with Castleman disease: Progression from mucous to mucocutaneous lesions with epitope-spreading phenomena.

Paraneoplastic pemphigus (PNP) is a frequently fatal autoimmune blistering disease of the skin and mucous membranes.(1) PNP is commonly associated with malignant neoplasms or haematological disorders ...

Editorial Comment to Biopsy undergrading in men with Gleason score 6 and fatal prostate cancer in the European Randomized study of Screening for Prostate Cancer Rotterdam.

Detection of digestive malignancies and post-gastrectomy complications via gastrointestinal fluid examination.

To date, gastric carcinoma (GC) is one of the common and fatal digestive malignancies worldwide. The prognosis of GC is not always satisfactory because of late diagnosis. Scholars are keen on discover...

Responses of soil methanogens, methanotrophs, and methane fluxes to land-use conversion and fertilization in a hilly red soil region of southern China.

Changes in land-uses and fertilization are important factors regulating methane (CH4) emissions from paddy soils. However, the responses of soil CH4 emissions to these factors and the underlying mecha...

Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction.

Insomnia is the most common sleep complaint which occurs due to difficulty in falling asleep or maintaining it. Most of currently available drugs for insomnia develop dependency and/or adverse effects...

Papillomaviruses: a systematic review.

In the last decades, a group of viruses has received great attention due to its relationship with cancer development and its wide distribution throughout the vertebrates: the papillomaviruses. In this...

News Articles [628 Associated News Articles listed on BioPortfolio]

Researchers Develop Potential Treatment for Fatal, Incurable Kidney Disease

NewsAffecting about 600,000 people in the U.S., autosomal dominant polycystic kidney disease (ADPKD) causes numerous fluid-filled cysts to form in the kidney.

Nonprofit Releases 2016 Dog Bite Fatality Statistics and Trends from 12-Year Dog Bite Fatality Data Set (2005 to 2016)

Austin, TX, February 21, 2017 --(PR.com)-- DogsBite.org, a national dog bite victims' group dedicated to reducing serious dog attacks, releases 2016 U.S. dog bite fatality statistics. Last year, ...

Gene puts thousands at risk of early heart attack death – Herald Scotland

MetroGene puts thousands at risk of early heart attack deathHerald ScotlandONE in every 250 people in Scotland carries a gene for a potentially deadly cholesterol disorder which, if undiagnosed, puts ...

217000 people in the UK have potentially fatal blood condition and they don’t know – Metro

Metro217000 people in the UK have potentially fatal blood condition and they don't knowMetroThe majority of people with a potentially fatal inherited blood condition are completely unaware they are af...

Successful insomnia treatment may require nothing more than a placebo

(Oxford University Press USA) A new study published in Brain indicates that successful treatment for insomnia may not actually require complicated neurofeedback (direct training of brain functions). R...

Lonza IPF airway cells

Lonza now offers cryopreserved lung fibroblasts isolated from donors diagnosed with idiopathic pulmonary fibrosis (IPF) for use in research into this potentially fatal condition. Normal lung fibroblas...

Fatal Neutropenic Enterocolitis With Docetaxel in France

Five fatal cases of neutropenic enterocolitis associated with a generic version of docetaxel have led one cancer centre to swap the drug for paclitaxel. Medscape Medical News

MDS Foods Inc, of Massillon, OH is Expanding the Current Recall to include Products Identified by Deutsch Kase Haus, LLC of Middlebury, Indiana from their 02/15/2017 Product Recall

Deutsch Kase Haus, LLC of Middlebury, Indiana, supplied MDS Foods with cheeses that have been found to be contaminated with the pathogenic organism Listeria Monocytogenes which can cause serious and s...

Kids' OD Risk Rises When Opioids Left Out at Home

MONDAY, Feb. 20, 2017 -- A child's risk of a potentially fatal drug overdose more than doubles if a parent brings home a prescription opioid painkiller like oxycodone, codeine or morphine, a new study...

Group supports patients with familial chylomicronemia syndrome

Familial chylomicronemia syndrome is a rare genetic disease caused by insufficient or impaired function of lipoprotein lipase, an enzyme responsible for triglyceride metabolism. This autosomal recessi...

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Companies [17 Associated Companies listed on BioPortfolio]

CurePSP

CurePSP is the leading nonprofit advocacy organization focused on prime of life neurodegenerative diseases – a spectrum of fatal brain disorders that often strike during a pe...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the ...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Clinical Trials [551 Associated Clinical Trials listed on BioPortfolio]

Study to Validate the Questionnaire Called IDSIQ™ in Patients With Insomnia Disorder

The main study objective is to assess the content validity and the psychometric characteristics of the Insomnia Daytime Symptoms and Impacts Questionnaire™ (IDSIQ™).

Management and Treatment of Patients With Severe Malnutrition in Intensive Care Unit: a Registry

Severe malnutrition can be seen as a low BMI, great weight loss, and even low levels of micronutrients. Current studies on severe malnutrition are mainly in patient with anorexia nervosa. ...

Self-acupressure for Insomnia: A Pilot Randomized Controlled Trial

Abstract Objectives: To explore the clinical effects of self-acupressure for treating insomnia delivered by a training course. Hypothesis: Subjects who have participated in the sel...

The British Heart Foundation SENIOR-RITA Trial

SENIOR-RITA is a multicentre prospective open-label trial randomizing patients presenting with type 1 NSTEMI aged ≥75 years between invasive and conservative treatment strategies, to com...

Study of Low Field Magnetic Stimulation (LFMS) on Measures of Sleep

Participants will be recruited and screened through ongoing studies in the sleep and anxiety disorders clinic. Participants with insomnia will be consented to complete several questionnair...

HLA-B*5801 Screening to Prevent Allopurinol-induced Severe Cutaneous Adverse Reaction

Allopurinol-induced severe cutaneous adverse reaction (SCAR) is a rare but fatal condition. Previous reports have reported that HLA-B*5801 is an important genetic risk factor significantly...

Efficacy and Safety of Ultra Small Dose Decitabine for the Lower Risk MDS Patients With Transfusion Dependent

Myelodysplastic syndrome (MDS) is widely recognized as a clonal hematopoietic stem cell disorder. Decitabine has been approved for the treatment of all subtypes of myelodysplastic syndrome...

Computerized Cognitive Behavioral Therapy Trial for Insomnia in Parkinson Disease

The therapeutic options are limited in Parkinson's Disease (PD) patients with insomnia and are often based on pharmacological treatments. It has been shown that the cognitive behavioral th...

Combination of Dextromethorphan and Memantine in Treating Bipolar Disorder

This is a research clinical trial of double-blind, stratified randomized, parallel group, two-centre study. It will be conducted in a total of 250~300 male and female subjects from the Dep...

Effects of Ginger on Muscle Soreness and Dysfunction Stemming From Downhill Running

The objective of the study is to determine whether five days of ginger (Zingiber officinale) supplementation is effective at reducing muscle soreness and improving muscle function followin...

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Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

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