Fatal Insomnia - Biotech, Pharma and Life Science Channel

07:26 EST 28th February 2015 | BioPortfolio

PubMed Articles [915 Associated PubMed Articles listed on BioPortfolio]

Suvorexant (Belsomra) for insomnia.

Selection of patients for sublingual immunotherapy (SLIT) versus subcutaneous immunotherapy (SCIT).

Allergy immunotherapy has been used to help alleviate symptoms of allergic diseases for over 100 years. In the setting of the recently approved sublingual immunotherapy, allergists are now faced with ...

Spontaneous remission of adult acute lymphoblastic leukemia: a very rare event.

A middle aged male presented to us with an unusual problem when his acute lymphoblastic leukemia (ALL) disappeared without any chemotherapy. We faced a dilemma whether to go ahead and treat his initia...

Invasive meningococcal disease in the 21st century-an update for the clinician.

Neisseria meningitidis is a gram-negative diplococcus, for which humans are the only reservoir. While colonization is common, invasive meningococcal disease in the form of meningitis or bacteremia can...

Change in Daily Ambulatory Activity and Cardiovascular Events in People with Impaired Glucose Tolerance.

Patients with pre-diabetes have a tenfold higher risk of developing Type 2 DM and a twofold higher risk of developing coronary heart disease compared to non-diabetics. Interventions targeted at those ...

Pharmacology for insomnia: Consider the options.

Community quarantine to interrupt ebola virus transmission - mawah village, bong county, liberia, august-october, 2014.

On September 30, 2014, the Bong County health officer notified the county Ebola task force of a growing outbreak of Ebola virus disease (Ebola) in Mawah, a village of approximately 800 residents. Duri...

Safety and immunogenicity of an investigational 4-component Staphylococcus aureus vaccine with or without AS03B adjuvant: Results of a randomized phase I trial.

We assessed the safety, reactogenicity and immunogenicity of a staphylococcal vaccine combining capsular polysaccharides types 5 and 8 (CPS5/8), conjugated to tetanus toxoid (TT), with mutated detoxif...

Management Practice and Mortality for Infants with Congenital Diaphragmatic Hernia.

Objective Congenital diaphragmatic hernia (CDH) is fatal in 20 to 40% of cases, largely due to pulmonary dysmaturity, lung hypoplasia, and persistent pulmonary hypertension. Evidence for survival be...

Coffee Consumption and Prostate Cancer Risk: A Meta-Analysis of Cohort Studies.

This meta-analysis was conducted to assess the association between coffee consumption and prostate cancer risk. Thirteen cohort studies with 34,105 cases and 539,577 participants were included in the ...

News Articles [526 Associated News Articles listed on BioPortfolio]

LoveYourBrain Kicks Off Brain Injury Awareness Month with National Fundraiser

Proceeds Used to Help Shift Culture Around Traumatic Brain Injury Recovery Through Yoga and Meditation LoveYourBrain Foundation announced today that, in honor of Brain Injury ...

America’s Stigma Around Methadone Puts Drug Addicts at an Increased Risk for Fatal Overdose

USA (PRWEB) February 27, 2015 The perennial debate between proponents of an abstinence based 12 step program style treatment argue that those who are for the use of a methadone and suboxone program...

Medical News Today: Persistent insomnia linked to higher risk of death, study finds

A new study shows that people who experience persistent insomnia have a higher risk of inflammation and premature death than those who experience intermittent insomnia.

Persistent insomnia and increased mortality risk

A connection between persistent insomnia and increased inflammation and mortality has been identified by a group of researchers from the University of Arizona. Their study, published in The American J...

Persistent Insomnia, Increased Mortality Risk: Link found by researchers

A connection between persistent insomnia and increased inflammation and mortality has been identified by a group of researchers. Their study found that people who suffer from persistent insomnia are a...

Many people with congenital heart disease living longer

At one time, many children born with congenital heart disease (CHD) suffered from issues that carried fatal prognoses. But that's changing, thanks to technological advancements.

Amphibian chytrid fungus reaches Madagascar

(Helmholtz Centre for Environmental Research - UFZ) The chytrid fungus, which is fatal to amphibians, has been detected in Madagascar for the first time. This means that the chytridiomycosis pandemic ...

Researchers find link between persistent insomnia and increased mortality risk

(Elsevier Health Sciences) A connection between persistent insomnia and increased inflammation and mortality has been identified by a group of researchers from the University of Arizona. Their study, ...

G-BA backs J&J's Sylvant

Germany's Federal Joint Committee (G-BA) concluded that Sylvant siltuximab from Johnson & Johnson (NYSE:JNJ) provides added benefit for patients with multicentric Castleman's disease (MCD) who are HIV...

CURE OM Director and Patient Advocate Sara Selig, MD Responds to Oliver Sacks Ocular Melanoma News

WASHINGTON, Feb. 25, 2015 /PRNewswire-USNewswire/ -- The Community United for Research and Education of Ocular Melanoma (CURE OM) commends Oliver Sacks for bravely sharing his experiences with oc...

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Companies [16 Associated Companies listed on BioPortfolio]

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the ...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Akashi Therapeutics, Inc.

Akashi Therapeutics is a clinical stage biopharmaceutical company whose mission is to develop treatments for Duchenne muscular dystrophy and other rare pediatric diseases. ...

Clinical Trials [364 Associated Clinical Trials listed on BioPortfolio]

ROOBY Trial Follow-up Extension

The Department of Veterans Affairs "Randomized On/Off Bypass" (ROOBY) Trial (CSP #517) was funded in 2001. ROOBY was designed to compare the short-term (30-day) and intermediate-term (1-ye...

Stepped Care Model for the Wider Dissemination of Cognitive-Behavioural Therapy for Insomnia Among Cancer Patients

Insomnia is very common in cancer patients. When left untreated, insomnia can lead to numerous serious consequences (e.g., psychological disorders) for the individual and significant costs...

Elderly Primary Insomnia Polysomnographic Study (0928-002)(TERMINATED)

The purpose of the study is to test the safety and effectiveness of an Investigational Drug on insomnia in the elderly.

Adult Polysomnography Primary Insomnia Cross Over Study (0928-049)(TERMINATED)

The purpose of this study is determine whether this drug will improve your insomnia in terms of decreasing your time to fall asleep and allowing you to stay asleep longer. The drug will b...

Eszopiclone Treatment & Cortisol Responsivity

This study was designed to use a sensitive neuroendocrine probe, the Dexamethasone/Corticotropin-Releasing Hormone (DEX/CRH) test, in a sample of healthy adults with insomnia. The primary ...

Study of Skin Tumors in Tuberous Sclerosis

Tuberous sclerosis is a rare, hereditary disease in which patients develop multiple tumors. Although not cancerous, the tumors can affect various organs, including the heart, lungs, kidney...

How to Ease the Withdrawal of Tranquilizers Among Older Consumers?

Benzodiazepines (BZD) are widely used to treat anxiety, insomnia, and depression. These drugs can have very serious side effects if they are taken over a long period of time. In addition t...

Brief Behavioral Therapy in Improving Sleep Disorders in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy

This randomized phase II trial studies how well brief behavioral therapy works in improving sleep disorders in patients with stage I-III breast cancer undergoing chemotherapy. Sleep disord...

Safety Study of Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase to Treat Pompe Disease

Pompe disease is an inherited condition of acid alpha-glucosidase (GAA) deficiency resulting in lysosomal accumulation of glycogen in all tissues. Glycogen accumulation leads to muscle dys...

Busulfan, Melphalan, Fludarabine and T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Followed by Post Transplantation Donor Lymphocyte Infusions

The patients are being offered a stem cell transplant. Stem cells are very early blood cells. They have not yet matured to become red or white blood cells or platelets. They have already r...

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Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

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