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Fatal Insomnia - Biotech, Pharma and Life Science Channel

01:29 EDT 29th August 2016 | BioPortfolio

PubMed Articles [833 Associated PubMed Articles listed on BioPortfolio]

Fatal Case of West Nile Neuroinvasive Disease in Bulgaria.

In Vivo Magnetic Resonance Imaging and Microwave Thermotherapy of Cancer Using Novel Chitosan Microcapsules.

Herein, we develop a novel integrated strategy for the preparation of theranostic chitosan microcapsules by encapsulating ion liquids (ILs) and Fe3O4 nanoparticles. The as-prepared chitosan/Fe3O4@IL m...

Educational report: A case of lacrimal sac rhinosporidiosis.

This article reports a presentation of lacrimal sac rhinosporidiosis and informs the reader of this uncommon but important diagnosis. A 36-year-old man from Pakistan presented with a 3-month history o...

Decision support in addiction: The development of an e-health tool to assess and prevent risk of fatal overdose. The ORION Project.

The application of e-health technology to the field of substance use disorders is at a relatively early stage, and methodological quality is still variable. Few have explored the extent of utilization...

Transfusion Related Acute Lung Injury (TRALI): A Single Institution Experience of 15 Years.

Transfusion related acute Lung injury (TRALI) though a serious blood transfusion reaction with a fatality rate of 5-25 % presents with acute respiratory distress with hypoxaemia and noncardiac pulmon...

Fat Grafting for Gluteal Augmentation: A Systematic Review of the Literature and Meta-Analysis.

With the increasing demand for gluteal fat augmentation, reports of fatal complications have surfaced. Therefore, the authors proposed to analyze the published techniques and compare different protoco...

Coronary artery stenting in a patient with progeria.

Progeria syndrome is a very rare disease with early demise in the second decade due to cardiovascular disease. Most events are sudden and fatal, leaving no time for medical or interventional therapies...

Fatal hepatic failure and pontine and extrapontine myelinolysis in XMEA.

Long non-coding RNA UCA1 contributes to the progression of oral squamous cell carcinoma via regulating WNT/β-catenin signaling pathway.

With the development of the functional genomics studies, a mass of long non-coding RNAs (LncRNA) were discovered from the human genome. LncRNAs serve as pivotal regulator of genes, which are able to g...

Trimethylamine-N-oxide (TMAO) predicts fatal outcomes in community-acquired pneumonia patients without evident coronary artery disease.

The pro-atherosclerotic metabolite trimethylamine-N-oxide (TMAO) is a risk factor for incident cardiovascular events and a potentially modifiable mediator of chronic inflammation through broad-spectru...

News Articles [639 Associated News Articles listed on BioPortfolio]

Glaxo Bets It Can Shake Up HIV Treatment

GlaxoSmithKline is pinning the future of its HIV business on an audacious bet: upending the decades-old triple-drug treatment strategy that has turned a fatal illness into a chronic condition.

Mexican teenage boy dies after a love bite from his girlfriend gave him a stroke – International Business Times UK

International Business Times UKMexican teenage boy dies after a love bite from his girlfriend gave him a strokeInternational Business Times UKThe 17-year-old is thought to have had a fatal seizure aft...

Garden for half hour to slash heart risk – Telegraph.co.uk

Telegraph.co.ukGarden for half hour to slash heart riskTelegraph.co.ukPensioners who spend just half an hour a day pottering in the garden, fishing or walking can reduce their fatal heart attacks by m...

Maker recalls fresh-cut vegetables from stores in Southeast

Fresh-cut vegetables are being recalled from grocery, discount and convenience stores across the Southeast because the food may be contaminated with potentially fatal Listeria bacteria.

Country Fresh Recalls Product Because Of Possible Health Risk

Country Fresh, LLC. of Conroe, Texas, is recalling 30,000 cases of various fresh-cut vegetable products (product descriptions attached), because they have the potential to be contaminated with Listeri...

Well: The Weekly Health Quiz: Happiness, Fracking and Fatal Music

Test your knowledge of this week’s health news.

Electroporation-mediated delivery of the FER gene in the resolution of trauma-related fatal pneumonia

Fateful evolution: New study improves accuracy of diagnosis for Barrett's oesophagus

A disorder known as Barrett's oesophagus (BE) affects some 200,000 Americans each year. The condition, which is caused by stomach acid damaging the lining of the oesophagus, can lead to the developm...

Synthetic Fentanyl Fueling Surge in Overdose Deaths: CDC

THURSDAY, Aug. 25, 2016 -- Deaths from overdoses of the synthetic narcotic fentanyl have surged in recent years, U.S. health officials say in a troubling new report. As more fentanyl was sold illegall...

New study uses evolutionary theory to predict cancer risk in patients with Barrett's esophagus

A disorder known as Barrett's esophagus (BE) affects some 200,000 Americans each year. The condition, which is caused by stomach acid damaging the lining of the esophagus, can lead to the development ...

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Companies [17 Associated Companies listed on BioPortfolio]

CurePSP

CurePSP is the leading nonprofit advocacy organization focused on prime of life neurodegenerative diseases – a spectrum of fatal brain disorders that often strike during a pe...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the ...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Clinical Trials [504 Associated Clinical Trials listed on BioPortfolio]

The Utility of Radiotherapy in the Management of Haemoptysis Secondary to Aspergillomata and Structural Lung Diseases

The sequelae of tuberculosis are still the commonest causes of haemoptysis in the developing world, where life-threatening haemoptysis remains a common and not infrequently fatal medical e...

Interest of Routine Screening for Hepatitis B and C in Patients Receiving Chemotherapy for Solid Tumors

Immunosuppression induced by cancer treatment increases the risk of hepatitis B virus (HBV) and hepatitis C virus (HCV) reactivations. These viral reactivations may be asymptomatic but can...

CoQ10 in Gulf War Illness

The primary objective of this clinical trial is to determine if treatment with ubiquinol, a form of coenzyme Q10, improves the physical function of men and women Veterans suffering from Gu...

Improving Mind/Body Health and Functioning With Integrative Exercise

There is evidence demonstrating that aerobic exercise improves many symptoms of Posttraumatic Stress Disorder (PTSD) including; anxiety, depression, insomnia, and cognition. With the goal ...

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-48816274

This is a 3-part study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of JNJ-48816274 in healthy participants after administration of single and repeated dose...

To Compare the Effectiveness of Suvorexant vs Placebo on Sleep Pressure in Hypertensives With Insomnia

The purpose of this study is to compare the effectiveness and safety of suvorexant versus placebo on sleep pressure and circadian rhythm in hypertensives with insomnia.

Regenerative Stem Cell Therapy for Stroke in Europe

Stroke is the second leading cause of death in the world population. When not fatal, stroke often results in disability, and secondary health problems affecting not only patients but also ...

Efficacy and Safety of ACT-541468 in Elderly With Insomnia Disorder

The primary objective of this study is to assess the effect of ACT-541468 on a measure of sleep maintenance (Wake after Sleep Onset or WASO) by polysomnography in elderly subjects with ins...

Efficacy and Safety of ACT-541468 in Adult Subjects With Insomnia Disorder

The primary objective of this study is to assess the effect of ACT-541468 on a measure of sleep maintenance (Wake after Sleep Onset or WASO) by polysomnography in subjects with insomnia di...

Adverse Drug Reactions With Fatal Outcome

The purpose of this study is to determine the incidence of drug-related deaths in a university hospital during the year 2015

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Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

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