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Fatal Insomnia - Biotech, Pharma and Life Science Channel

11:14 EDT 18th May 2013 | BioPortfolio

PubMed Articles [ 1669 Associated PubMed Articles listed on BioPortfolio]

Radix Puerariae: An overview of Its Chemistry, Pharmacology, Pharmacokinetics, and Clinical Use.

Radix Puerariae has been traditionally used for the treatment of diarrhea, acute dysentery, deafness and cardiovascular diseases. Yege (Gegen or Radix Puerariae lobatae), the dried root of Pueraria lo...

Non-recovery of ACT in a patient with heparin-induced thrombocytopenia type II during mitral valve replacement using argatroban anticoagulation.

Argatroban was used as the anticoagulant during cardiopulmonary bypass (CPB) in a patient with heparin-induced thrombocytopenia (HIT) type II undergoing mitral valve replacement. Dosage was reduced be...

Fatal overwhelming postsplenectomy infection caused by Streptococcus pneumoniae in mothers within 1 year after delivery: case report.

Invasive pneumococcal disease (IPD) has a high mortality. Although preventive strategies including vaccination have been established for children, less attention has been devoted to pregnant and postn...

Fatal skin and pulmonary infection caused by Hormographiella aspergillata in a leukaemic patient: case report and literature overview.

Invasive systemic fungal infections are a major cause of morbidity and mortality in patients after hematopoietic stem cell transplantation. We report the case of a fatal infection with Hormographiella...

The Predictive Value of the In Vitro Platelet Toxicity Assay (iPTA) for the Diagnosis of Hypersensitivity Reactions to Sulfonamides.

Drug hypersensitivity reactions (DHRs) are rare but potentially fatal adverse drug reactions (ADRs). A reliable test to diagnose DHRs would be a major advance in the clinical care for patients and in...

Molecular pathology of pulmonary edema in forensic autopsy cases with special regard to fatal hyperthermia and hypothermia.

Fatalities due to an extreme ambient temperature might present with poor or nonspecific pathologies; thus, the diagnosis of the cause of death in such cases is one of the most difficult tasks in foren...

The influence of stimulants on truck driver crash responsibility in fatal crashes.

Given the monotony and extended driving periods inherent in transport truck driving, drivers might rely on stimulants to sustain attention and combat fatigue. Research indicates that stimulant use imp...

Unexpected death: Anaphylactic intraoperative death due to Thymoglobulin carbohydrate excipient.

Anaphylactic shock is a life-threatening allergic response characterized by severe hypotension, inducing tissue hypoperfusion with possible multi-organ failure and death. We describe the first case of...

Extended suicide by use of a chain saw.

Injuries caused by chain saws are mostly seen due to accidents. Suicides by chain saws are rare, but some cases have already been described. We present the case of homicide on a child by a chain saw f...

Asphyxial death related to postextraction hematoma in an elderly man.

We here report an autopsy case of a man in his seventies who died from asphyxia due to compression of the trachea caused by postextraction bleeding after extraction of his left mandibular third molar...

News Articles [ 1242 Associated News Articles listed on BioPortfolio]

Insomnia Treatment | How “Sleep Brain Waves” Helps People Cure Their Insomnia – HealthReviewCenter.com

“Sleep Brain Waves," developed by Ryan Bolera, is a new insomnia treatment method that reveals the main causes of insomnia and guides on how to treat these causes. A full Sleep Brain Waves revi...

Bel Marra Health Reports on a New Study Revealing a Natural Remedy for Hypertension, Insomnia, and Aging

Bel Marra Health, who offers high-quality, specially formulated vitamins and nutritional supplements, reports a new study that reveals a natural way to reduce stress, anxiety, and high blood pressure,...

Relationship Between Sleep Duration And Suicidal Thoughts In People With Insomnia.

Results of a new study show that every one-hour increase in sleep duration was associated with a 72 percent decrease in the likelihood of moderate or high suicide risk, in comparison with low risk. Da...

New Nimodipine Formulation Aimed At Reducing Fatal Medication Errors

Nymalize, an oral formulation of brain hemorrhage treatment nimodipine, aims to minimize serious risks associated with incorrect administration of older forms of the drug.

SARS-Like Virus Spreads From Patient to Nurse: WHO

Two health workers in Saudi Arabia have become infected with a potentially fatal new SARS-like virus after catching it from patients in their care - the first evidence of such transmission within a ho...

Extra Sleep Drastically Reduces Suicidal Thoughts In Insomniacs

redOrbit Staff & Wire Reports - Your Universe Online Insomniacs who find themselves having suicidal thoughts could benefit from a few more hours of sleep, according to a new study which has repor...

Opiate Withdrawal Fear Could Be Major Cause for Overdose Deaths; Pure Health Group Inc(TM) Provides New Rapid Response Release Technology Detox Solution to Prevent Deaths

Denver, Colorado (PRWEB) May 16, 2013 Opiate withdrawal is no picnic: anxiety, depression, nausea, vomiting, insomnia, restless leg syndrome, spiking fevers and general pain are just some of the...

New study finds association between sleep duration and suicide risk in insomnia

A new study found a relationship between sleep duration and suicidal thoughts in people with insomnia.

More Effective Treatment Of Complex Infections Likely With Cutting-Edge Bacteria Research

Bacteria are life forms, which, like all other life forms, struggle for the best living conditions for themselves. Therefore they will try to avoid getting attacked by the human immune system, and the...

Half Of All Adult Female Deaths In Rural Bangladesh Due To Non-Communicable Diseases

While global attention has for decades been focused on reducing maternal mortality, population-based data on other causes of death among women of reproductive age has been virtually non-existent. A st...

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Companies [ 10 Associated Companies listed on BioPortfolio]

Isabel Healthcare Inc.

Isabel Healthcare Inc. was founded in 2000 by Jason Maude and is named after Maude’s daughter who almost died after a potentially fatal illness was not recognized. Isabel Hea...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the...

Somaxon Pharmaceuticals, Inc.

Headquartered in San Diego, CA, Somaxon Pharmaceuticals, Inc. is a specialty pharmaceutical company focused on the in-licensing, development and commercialization of proprietary b...

StemCells, Inc.

StemCells, Inc. is focused on the development and commercialization of cell-based technologies. In its cellular medicine programs, StemCells is targeting diseases of the central n...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Integrative Insomnia & Sleep Health Center

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Fisher Wallace Laboratories

Founded by Charles Avery Fisher, the son of stereo pioneer Avery Fisher, Fisher Wallace Laboratories manufactures the Fisher Wallace Cranial Stimulator, a cranial electrotherapy stimulation (CES) devi...

Clinical Trials [ 347 Associated Clinical Trials listed on BioPortfolio]

Chemotherapy Treatment for Children With Intraocular Germ-Line Retinoblastoma

Retinoblastoma is an unusual cancer of early childhood involving tumor is both eyes or, in certain circumstances, one eye only. This condition is the result of an abnormal gene which makes...

Randomized Clinical Trial of 4RIF Vs. 9INH for the Treatment of Latent TB

Although effective medications to treat and even prevent Tuberculosis (TB) have been available for over 40 years, TB remains the most important infectious cause of mortality among adults i...

Use of Probiotics to Prevent Cholangitis in Children With Biliary Atresia After the Kasai Portoenterostomy

Abstract Biliary atresia (BA) is an idiopathic, progressive, and fatal disease if untreated. Since Kasai first introduced the operation for BA in 1959, there have been encouraging results...

Failed Retrieval of Inferior Vena Cava (IVC) Filters: Long-Term Outcomes

The inferior vena cava (IVC) is a large vein that enters the bottom part of the heart. Venous blood from the lower portion of the body drains into the IVC. The IVC then returns blood back...

Safety and Efficacy Study of Antisense Oligonucleotides in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD), a fatal muscle degenerative disorder, arises from mutations in the dystrophin gene. Antisense therapy with the use of antisense oligonucleotides (AON) ha...

Effects of Cognitive-Behavioral Therapy on Sleep Disturbance in Peritoneal Dialysis Patients

Sleep disturbance is prevalent in chronic dialysis patients and there is a negative correlation between the quality of life and overall survival and sleep disturbance in them. Cognitive-be...

Dexamethasone Study: Impact on Quality of Life of Continuing Dexamethasone Following Emetogenic Chemotherapy

Background: Dexamethasone is a steroid, which is often given into the vein before chemotherapy to help control acute nausea and vomiting. It can also be given as an oral tablet for patient...

Cognitive Behavioral Therapy for Insomnia in Chronic Pain Patients

This study of cognitive behavioral therapy for insomnia in chronic pain patients is a randomized, controlled clinical trial of parallel groups with three and six months follow up.

Phase 3 Trial for AML Patients in CR2 Comparing 8Gy TBI /Fludarabine to Conditioning With TBI 12Gy/Cyclophosphamide

For patients with acute myeloid leukemia (AML), allogeneic hematopoetic stem cell transplantation (HSCT) is one of the most potent treatment options currently available. In order to overco...

Effects of Lithium and Divalproex`on Brain-Derived Neurotrophic Factor in Huntington's Disease

This study will examine whether lithium carbonate, given alone or with divalproex, increases the amount of brain-derived neurotrophic factor (BDNF) in the spinal fluid of patients with Hun...

Videos

Fatal Familial Insomnia - Documentary

A very interesting documentary about Fatal Familial Insomnia, showing cases and relatives of victims dealing with the disease. ABC production. More about FFI...

Medical and Biotech [MESH] Definitions

Insomnia, Fatal Familial

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

11-beta-hydroxysteroid Dehydrogenase Type 2

An high-affinity, NAD-dependent 11-beta-hydroxysteroid dehydrogenase that acts unidirectionally to catalyze the dehydrogenation of CORTISOL to CORTISONE. It is found predominantly in mineralocorticoid target tissues such as the KIDNEY; COLON; SWEAT GLANDS; and the PLACENTA. Absence of the enzyme leads to a fatal form of childhood hypertension termed, APPARENT MINERALOCORTICOID EXCESS SYNDROME.

Henipavirus

A genus in the subfamily PARAMYXOVIRINAE, family PARAMYXOVIRIDAE. It contains species that infect and cause potentially fatal disease in a number of host species, including humans.

Purpura Fulminans

A severe, rapidly fatal reaction occurring most commonly in children following an infectious illness. It is characterized by large, rapidly spreading skin hemorrhages, fever, or shock. Purpura fulminans often accompanies or is triggered by DISSEMINATED INTRAVASCULAR COAGULATION.

Prions

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

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