Fatal Insomnia - Biotech, Pharma and Life Science Channel

09:38 EST 31st January 2015 | BioPortfolio

PubMed Articles [950 Associated PubMed Articles listed on BioPortfolio]

Spontaneous remission of adult acute lymphoblastic leukemia: a very rare event.

A middle aged male presented to us with an unusual problem when his acute lymphoblastic leukemia (ALL) disappeared without any chemotherapy. We faced a dilemma whether to go ahead and treat his initia...

Fast Neutron Radiotherapy in the Treatment of Malignant Pleural Mesothelioma.

Malignant pleural mesothelioma (MPM) is a fatal disease lacking standardized treatment. We describe the use of fast neutron radiation therapy in MPM patients referred to the Department of Radiation On...

Radiation Safety of Sealed Radioactive Sources.

Sealed radioactive sources are used in a wide variety of occupational settings and under differing regulatory/licensing structures. The definition of a sealed radioactive source varies between U.S. re...

Fatal Meningoencephalitis in Child and Isolation of Naegleria fowleri from Hot Springs in Costa Rica.

Outbreaks of West Nile virus in captive waterfowl in Ontario, Canada.

The detrimental effects of West Nile virus (WNV) have been well characterized in several taxonomic groups of North American birds, such as corvids and raptors. Relatively less is known about the virus...

Rate of deaths due to child abuse and neglect in children 0-3 years of age in Germany.

In recent years, increasing attention has been paid to the issue of (fatal) child abuse and neglect, largely due to the media attention garnered by some headline-grabbing cases. If media statements ar...

Preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: What can be done?

Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is the most common complication of endoscopic retrograde cholangiopancreatography. The incidence of post-endoscopic retrograde ch...

Serum ferritin correlates with Glasgow coma scale scores and fatal outcome after severe traumatic brain injury.

Abstract Objectives: Severe traumatic brain injury (TBI) is associated with a 30-70% mortality rate. Nevertheless, in clinical practice there are no effective biomarkers for the prediction of fatal ou...

Treating Insomnia Improves Mood State, Sleep, and Functioning in Bipolar Disorder: A Pilot Randomized Controlled Trial.

Objective: To determine if a treatment for interepisode bipolar disorder I patients with insomnia improves mood state, sleep, and functioning. Method: Alongside psychiatric care, interepisode bipolar ...

Compartment-Specific and Sequential Role of MyD88 and CARD9 in Chemokine Induction and Innate Defense during Respiratory Fungal Infection.

Aspergillus fumigatus forms ubiquitous airborne conidia that humans inhale on a daily basis. Although respiratory fungal infection activates the adaptor proteins CARD9 and MyD88 via C-type lectin, Tol...

News Articles [608 Associated News Articles listed on BioPortfolio]

Litchi fruit suspected in mystery illness in India

A mysterious and sometimes fatal brain disease that has afflicted children in northeastern India for years could be linked to a toxic substance in litchi fruits, US researchers said Thursday.

Parent Project Muscular Dystrophy Awards UCLA $50,000 Exploratory Grant for Evaluation of Exon Skipping Enhancers in Duchenne

HACKENSACK, N.J., Jan. 29, 2015 /PRNewswire-USNewswire/ -- Parent Project Muscular Dystrophy (PPMD), a nonprofit organization dedicated to the fight to end Duchenne muscular dystrophy (Duchenne), anno...

Study Links Allergy And Depression Medications To Increased Risk For Dementia

Results from a new study provide increasing evidence that anticholinergic drugs—commonly used to treat allergies, insomnia or even depression--may heighten the risk for dementia in older persons. Th...

Study shows menopause does not increase or create difficulty sleeping

Women in their late thirties and forties who have trouble sleeping are more than three times more likely to suffer sleep problems during menopause than women who have an easier time getting shut-eye, ...

Xarelto Lawsuits Move Forward As FDA Approves Label Changes For Prescription Blood Thinner, The Oliver Law Group Comments

Xarelto Drug Safety Label Warns Bleeding Is A Common Adverse Reaction Of The Blood Thinner And Xarelto Bleeding Side-Effects Lawsuits Claim The Anticoagulant Does Not Have An Antidote Should Severe Bl...

Gersowitz Libo & Korek, P.C. New York Personal Injury Attorney Jeff S. Korek Urges Greater Attention to Safety Procedures Following a Fatal Fall Down a NYC Elevator Shaft

New York personal injury attorney Jeff S. Korek of Gersowitz Libo & Korek, P.C. urges construction workers who work near elevator shafts to be extra vigilant following an accident in NYC in which ...

Get the Extra Tools for Stress-Related Health Issues through The Prince Synergy

LOS ANGELES, Jan. 28, 2015 /PRNewswire/ -- The Prince Synergy (www.ThePrinceSynergy.com) announces its programs on how to stay young and healthy under stress, related video on YouTube, https://ww...

New compounds more potent in combatting brain-eating amoeba's fatal infection

A University of South Florida Health College of Public Health professor and his team of researchers have zeroed in on compounds that could one day lead to fast-acting treatments for the fatal infectio...

Medical News Today: Lung cancer to overtake breast cancer as most fatal among European women

Predictions for 2015 estimate that, for the first time, the death rates for lung cancer among women in Europe will exceed those for breast cancer.

NMS Labs Recognizes an Increase in Heroin and Fentanyl Use

In recent years there has been a sharp rise in heroin use and heroin overdoses. According to recent data from the National Institute on Drug Abuse (NIDA), a rise in heroin abuse i...

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Companies [16 Associated Companies listed on BioPortfolio]

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the ...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Akashi Therapeutics, Inc.

Akashi Therapeutics is a clinical stage biopharmaceutical company whose mission is to develop treatments for Duchenne muscular dystrophy and other rare pediatric diseases. ...

Clinical Trials [362 Associated Clinical Trials listed on BioPortfolio]

Eszopiclone Treatment & Cortisol Responsivity

This study was designed to use a sensitive neuroendocrine probe, the Dexamethasone/Corticotropin-Releasing Hormone (DEX/CRH) test, in a sample of healthy adults with insomnia. The primary ...

Study of Skin Tumors in Tuberous Sclerosis

Tuberous sclerosis is a rare, hereditary disease in which patients develop multiple tumors. Although not cancerous, the tumors can affect various organs, including the heart, lungs, kidney...

How to Ease the Withdrawal of Tranquilizers Among Older Consumers?

Benzodiazepines (BZD) are widely used to treat anxiety, insomnia, and depression. These drugs can have very serious side effects if they are taken over a long period of time. In addition t...

Brief Behavioral Therapy in Improving Sleep Disorders in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy

This randomized phase II trial studies how well brief behavioral therapy works in improving sleep disorders in patients with stage I-III breast cancer undergoing chemotherapy. Sleep disord...

Safety Study of Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase to Treat Pompe Disease

Pompe disease is an inherited condition of acid alpha-glucosidase (GAA) deficiency resulting in lysosomal accumulation of glycogen in all tissues. Glycogen accumulation leads to muscle dys...

Busulfan, Melphalan, Fludarabine and T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Followed by Post Transplantation Donor Lymphocyte Infusions

The patients are being offered a stem cell transplant. Stem cells are very early blood cells. They have not yet matured to become red or white blood cells or platelets. They have already r...

Atripla to Raltegravir Switch Study for CNS Toxicity

The purpose of the study is to investigate the benefits of switching away from efavirenz (part of the combination pill, Atripla®) in patients with central nervous system side effects (suc...

Randomized Controlled Trial of a Self-help Book for Insomnia in Patients With Co-morbid OSA and Insomnia

Obstructive sleep apnea (OSA) is a common sleep disorder treated with continuous positive airway pressure (CPAP). Some OSA patients also suffer from co-morbid insomnia. CPAP treatment may ...

Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors

This randomized clinical trial studies a cognitive-behavioral intervention to treat worry, uncertainty, and insomnia in cancer survivors. Counseling may reduce anxiety and insomnia as well...

Study Comparing Ticagrelor With Aspirin for Prevention of Vascular Events in Patients Undergoing CABG

This study (TiCAB) is designed as a pivotal efficacy and safety study of Ticagrelor in patients undergoing coronary artery bypass operation. It is designed for the prevention of fatal and ...

Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

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