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Fatal Insomnia - Biotech, Pharma and Life Science Channel

03:11 EST 4th December 2016 | BioPortfolio

PubMed Articles [829 Associated PubMed Articles listed on BioPortfolio]

Fatal Case of West Nile Neuroinvasive Disease in Bulgaria.

In Vivo Magnetic Resonance Imaging and Microwave Thermotherapy of Cancer Using Novel Chitosan Microcapsules.

Herein, we develop a novel integrated strategy for the preparation of theranostic chitosan microcapsules by encapsulating ion liquids (ILs) and Fe3O4 nanoparticles. The as-prepared chitosan/Fe3O4@IL m...

The Relief Effects of Ramelteon on Refractory Chronic Migraine: A Case Report.

The selective melatonin receptor agonism effect of ramelteon is useful for insomnia. Here we wanted to present a refractory chronic migraine case, who had significant improvements in migraine after us...

Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

Immune checkpoint inhibitors have improved clinical outcomes associated with numerous cancers, but high-grade, immune-related adverse events can occur, particularly with combination immunotherapy. We ...

Cardiovascular Toxicities of Small Molecule TKIs: An Opportunity for Systems-Based Approaches.

Once universally considered a rapidly fatal condition, cancer has increasingly become a chronic medical condition and co-morbidities and adverse effects of cancer therapies have become increasingly si...

Safety and Wound Outcomes Following Genetically Corrected Autologous Epidermal Grafts in Patients With Recessive Dystrophic Epidermolysis Bullosa.

Recessive dystrophic epidermolysis bullosa (RDEB) is a devastating, often fatal, inherited blistering disorder caused by mutations in the COL7A1 gene encoding type VII collagen. Support and palliation...

Cellular transplant therapies for globoid cell leukodystrophy: Preclinical and clinical observations.

Globoid cell leukodystrophy (GLD) is a progressive neurodegenerative disorder caused by the deficiency of galactocerebrosidase (GALC), resulting in accumulation of toxic metabolites in neural tissues....

Can psychosine and galactocerebrosidase activity predict early-infantile Krabbe's disease presymptomatically?

Krabbe's disease (KD) is a fatal neurodegenerative disorder, with the early-infantile form (EIKD) defined by onset of symptoms before age 6 months. Early and highly accurate identification of EIKD is ...

A microglial hypothesis of globoid cell leukodystrophy pathology.

Globoid cell leukodystrophy (GLD), also known as Krabbe's disease, is a fatal demyelinating disease accompanied by the formation of giant, multinucleated cells called globoid cells. Previously believe...

Clinical, electrophysiological, and biochemical markers of peripheral and central nervous system disease in canine globoid cell leukodystrophy (Krabbe's disease).

Globoid cell leukodystrophy (GLD), or Krabbe's disease, is a debilitating and always fatal pediatric neurodegenerative disease caused by a mutation in the gene encoding the hydrolytic enzyme galactosy...

News Articles [642 Associated News Articles listed on BioPortfolio]

Biomarker Could Predict Which Formerly Treated Cancer Patients Could Develop Deadly Form of Leukemia

NewsPatients successfully treated for breast, colon and other cancers can go on to develop an often-fatal form of leukemia.

ASH 2016: Biomarker may predict which formerly treated cancer patients will develop highly fatal form of leukaemia

A study conducted by researchers at The University of Texas MD Anderson Cancer Center revealed pre-leukaemic mutations, called clonal haematopoiesis, may predict whether patients develop t-MNs. Clona...

ASH 2016: Biomarker may predict which formerly treated cancer patients will develop highly fatal form of leukemia

A study conducted by researchers at The University of Texas MD Anderson Cancer Center revealed pre-leukaemic mutations, called clonal haematopoiesis, may predict whether patients develop t-MNs. Clona...

Biomarker may predict which formerly treated cancer patients will develop highly fatal form of leukemia

(University of Texas M. D. Anderson Cancer Center) Patients successfully treated for breast, colon and other cancers can go on to develop an often-fatal form of leukemia, sometimes years after complet...

Royal Seafood Baza, Inc. Recalls Various Ready to Eat Herring Products Because of Possible Health Risk

Royal Seafood Baza, Inc. of Staten, Island, New York is recalling various refrigerated ready to eat herring products because they have the potential to be contaminated with Listeria monocytogenes, an ...

Drug for one hepatitis type may activate another: watchdog

Drugs against one type of hepatitis may activate another, sometimes with fatal consequences, Europe's medicines watchdog warned on Friday.

Could women with mitochondrial diseases prevent passing them onto their children?

A technique that could allow women with mitoch

Non-GMO RNA silencing technique may be used to combat citrus greening disease

AUM LifeTech in collaboration with the United States Department of Agriculture has developed a novel Non-GMO RNA silencing approach for bacteria, insect and pathogen control with a focus on citrus tr...

Online insomnia program can improve sleep for many

An online program designed to help people overcome insomnia significantly improves both the amount and quality of sleep, a new University of Virginia study has found.

Immune System Cells Cause Severe Malaria Complication in Mouse Model

Immune system cells known as cytotoxic T cells attack blood vessels and cause fatal swelling in the brains of mice with a condition that mirrors a severe complication of malaria in humans. These are t...

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Companies [17 Associated Companies listed on BioPortfolio]

CurePSP

CurePSP is the leading nonprofit advocacy organization focused on prime of life neurodegenerative diseases – a spectrum of fatal brain disorders that often strike during a pe...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the ...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Clinical Trials [527 Associated Clinical Trials listed on BioPortfolio]

MRA With Feraheme in HHT

Magnetic resonance (MR) imaging is performed with contrast agents to highlight the blood vessels and allow interpretation and diagnosis of blood vessel abnormalities. HHT (Hereditary Hemor...

Auriculotherapy on Older People With Insomnia

Objective To determine the optimum treatment protocol of auriculotherapy (AT) on the improvement of sleep conditions and quality of life on the elders with insomnia. Research hypothesis T...

Treatment Resistant Depression and Insomnia in Older Veterans

The purpose of this pilot study is to obtain information about older Veterans' preferences for treatment of depression and insomnia and to pilot test the feasibility and clinical effect of...

Non-invasive Estimation of Pulmonary Artery Pressure in Healthy Subjects by Electrical Impedance Tomography

Pulmonary hypertension (PH) is a condition characterized by a sustained elevation in pulmonary artery pressure (PAP) above 25 mmHg assessed by right heart catheterization. PH is fatal in a...

Preventive Effect of Celecoxib on Sorafenib-related Hand Foot Syndrome, a Single Center, Randomized Controlled Clinical Trail

Hepatocellular carcinoma (HCC) is a common fatal malignant tumor, although with the popularity of health examination, most patients were diagnosed as HCC in advanced stages so far. Sorafen...

Equivalence of Monitoring by a Nurse Practitioner for Patients With Digestive Cancer

With 42,150 new cases per year, colorectal cancer is the third cause of cancer in France according to the latest report from the Institut national du Cancer (INCa). Second leading cause of...

Biobehavioral Intervention to Enhance Hematopoietic Stem Cell Transplant Recovery

The goal of this project is to conduct a pilot randomized clinical trial (RCT) to evaluate the feasibility of a brief, behavioral intervention to improve recovery following hematopoietic s...

Long-term Study of Lemborexant in Insomnia Disorder

The key objectives of this study are to determine, using sleep diaries, whether lemborexant at the doses 5 milligrams (mg) and 10 mg is superior to placebo on subjective sleep onset, subje...

OsteoArthritis and Therapy for Sleep

Osteoarthritis (OA) pain affects 50 percent of older adults, more than half of whom also experience significant sleep disturbance. This randomized trial will determine whether a telephone-...

Effect of Background Noise on Sleep Quality

Insufficient and low-quality sleep is a major public health problem that has been linked to motor vehicle crashes, industrial disasters, and medical and other occupational errors. Persons ...

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Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

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