Fatal Insomnia - Biotech, Pharma and Life Science Channel

10:33 EDT 2nd October 2014 | BioPortfolio

PubMed Articles [930 Associated PubMed Articles listed on BioPortfolio]

Insomnia Treatment Experience and Preferences Among Veterans Affairs Primary Care Patients.

Insomnia is common, but undertreated, among primary care patients. Within the Veterans Health Administration (VA), increasing attention has been given to the treatment of insomnia within primary care ...

Identification of a new disease cluster of Pemphigus vulgaris with autoimmune thyroid disease, rheumatoid arthritis, and type I diabetes.

Pemphigus vulgaris (PV) is a potentially fatal autoimmune blistering skin disease. It is known that individuals suffering from autoimmune diseases, such as PV, as well as family members, are at increa...

Neuropathology: SY21-2 MUCOR FUNGAL ENCEPHALITIS: CASE PRESENTATION.

Mucormycosis is a rare and often fatal infection caused by fungi of the Mucorales order, commonly affecting immunocompromised patients and adults with diabetic ketoacidosis. Infants are infected throu...

Infectious Diseases and Tropical Disease Pathology: SY16-3 PYTHIOSIS: AN ENDEMIC FATAL INFECTIOUS DISEASE.

Pythiosis is a life threatening infectious disease of humans and animals living in tropical and subtropical areas of the world. The causative agent is the fungus-like microorganism Pythium insidiosum,...

Infectious Diseases and Tropical Disease Pathology: SS16-1 UNDERSTANDING ENTEROVIRUS 71 INFECTION AND NEUROPATHOGENESIS: PERSPECTIVE FROM HUMAN AND ANIMAL MODEL STUDIES.

Enterovirus 71 (EV71) (family Picornaviridae, genus Human Enterovirus A) causes the relatively mild hand, foot and mouth disease in children. However, rare complications including meningitis, acute tr...

Fatal Intoxications Associated with the Designer Opioid AH-7921.

AH-7921 (3,4-dichloro-N-[(1-dimethylamino)cyclohexylmethyl]benzamide) is a designer opioid with ∼80% of morphine's µ-agonist activity. Over a 6-month period, we encountered nine deaths where AH-792...

A fatal intoxication of 2,5-dimethoxy-4-chloroamphetamine: a case report†.

Designer drugs appear to be increasing in popularity because of the ease of obtaining these constituents, the lack of ability to identify the substance(s) in routine drug screening, the appeal of the ...

Fatal Methadone Toxicity: Potential Role of CYP3A4 Genetic Polymorphism.

Methadone is difficult to administer as a therapeutic agent because of a wide range of interindividual pharmacokinetics, likely due to genetic variability of the CYP450 enzymes responsible for metabol...

Determining zolpidem compliance: urinary metabolite detection and prevalence in chronic pain patients.

Zolpidem (Ambien(®)) is the most prescribed insomnia treatment in the USA; however, little is known about zolpidem metabolite excretion in chronic pain patients. As zolpidem is extensively metabolize...

Analysis of zolpidem in postmortem fluids and tissues using ultra-performance liquid chromatography-mass spectrometry.

Zolpidem is a nonbenzodiazepine sedative hypnotic drug used for the short-term treatment of insomnia. While quite effective in producing sedation, zolpidem has potentially hazardous side effects when ...

News Articles [733 Associated News Articles listed on BioPortfolio]

Energy drinks cause insomnia and nervousness in athletes

A study analysing the positive and negative effects of energy drinks on athletes has seen that, although in principle their sports performance was seen to improve by between 3% and 7%, there was also ...

How Your Gut Microbes Survive When You're Too Sick to Eat

A bout of the flu can cause even the biggest foodie to abandon the kitchen and forgo regular meals. This change in diet not only affects the waistline, but also starves the good bacteria dwelling in t...

Genes indicate resistance to malaria

Five genes that play a role in conferring natural resistance or making people more susceptible to severe malaria have been identified. The findings could lead to a better understanding of the pr...

Intervention helps decrease 'mean girl' behaviors, researchers find

Relational aggression, or "mean girl" bullying, is a popular subject in news and entertainment media. This nonphysical form of aggression generally used among adolescent girls includes gossiping, rumo...

CTD Holdings Names New Board Chairman

ALACHUA, FL--(Marketwired - October 01, 2014) - CTD Holdings, Inc. (OTCQB: CTDH), a family of biotechnology growth companies that distribute and manufacture cyclodextrin-based products, including the...

Treating Insomnia Lowers Risk for Chronic Diseases

Intervention helps decrease 'mean girl' behaviors, MU researchers find

(University of Missouri-Columbia) Relational aggression, or 'mean girl' bullying, is a popular subject in news and entertainment media. This nonphysical form of aggression generally used among adolesc...

Comprehensive Study of Allergic Deaths in U.S. Finds Medications are Main Culprit

BRONX, N.Y., Sept. 30, 2014 /PRNewswire-USNewswire/ -- Medications are the leading cause of allergy-related sudden deaths in the U.S., according to an analysis of death certificates from 1999 to 2010,...

Medications are main culprit of allergic deaths in U.S., comprehensive study finds

Medications are the leading cause of allergy-related sudden deaths in the U.S., according to an analysis of death certificates from 1999 to 2010. The study also found that the risk of fatal drug-induc...

AAAAI & JACI: In Practice Publish First Known Study on Food Allergies and Nannies

Nannies have “good grasp” of basic food allergies but some misconceptions are dangerous Milwaukee, WI (PRWEB) September 30, 2014 Food allergies affect approximately 15 million people in the Unite...

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Companies [16 Associated Companies listed on BioPortfolio]

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the ...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Akashi Therapeutics, Inc.

Akashi Therapeutics is a clinical stage biopharmaceutical company whose mission is to develop treatments for Duchenne muscular dystrophy and other rare pediatric diseases. ...

Clinical Trials [349 Associated Clinical Trials listed on BioPortfolio]

Effects of 'R' (Electro-kinetic Beverage) on Insomnia, Fatigue, and Depression in Breast Cancer Patients Having Adjuvant Chemo

The purpose of this study is to evaluate the effects of consuming "R" on quality of life in the areas of insomnia, fatigue, and depression in female breast cancer patients receiving multi-...

Treating Sleep Problems in VA Adult Day Health Care

The Veterans Millennium Health Care and Benefits Act (Millennium Act) of 1999 mandated the Department of Veterans Affairs (VA) to provide non-institutional long-term care to veterans. Adul...

Cardiovascular Disease (CVD) in Haemophilia

Life expectancy of hemophilia patients has improved considerably during the past decades and is approaching that of the general population. Hemophilia patients are therefore likely to be c...

Systolic Hypertension in the Elderly Program (SHEP)

The primary objective was to assess whether long-term administration of antihypertensive therapy to elderly subjects with isolated systolic hypertension reduced the combined incidence of f...

A Study of AS-101 in Patients With AIDS or AIDS Related Complex (ARC)

To determine the toxic effects of AS-101 at various doses in patients with AIDS or AIDS related complex. Also to determine the effect of various doses of AS-101 on immune functions and the...

A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS

To evaluate the effectiveness and toxicity of oral azithromycin and pyrimethamine as acute therapy for toxoplasmic encephalitis in AIDS patients. To assess the toxicity and effectiveness o...

Genetic and Family Studies of Inherited Muscle Diseases

The purposes of this study are to identify gene mutations in patients with the muscle diseases phosphofructokinase (PFK) deficiency, acid maltase deficiency (GAA deficiency) and to learn m...

Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives

Bone marrow transplants (BMT) are one form of treatment for disorders of the blood, including leukemia. However, because the procedure is often associated with potentially life-threatenin...

A Study of Health-Related Quality of Life in HIV-Infected Patients Undergoing Structured Treatment Interruptions of Highly Active Antiretroviral Therapy

This study will examine and compare the health-related quality of life and degree of symptom discomfort in two groups of patients receiving intensive drug therapy for HIV infection. One gr...

L-5-HTP-Related EMS

In 1989 more than 1500 people who took the dietary supplement L-tryptophan for insomnia and depression developed eosinophilia myalgia syndrome (EMS)-a potentially fatal disease characteriz...

Videos

Dying To Sleep - Documentary

This documentary deals with a very rare and unusual prion disease called Fatal Familial Insomnia or FFI for short. FFI is a prion disease that targets the th...

Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

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