Fatal Insomnia - Biotech, Pharma and Life Science Channel

09:33 EDT 6th July 2015 | BioPortfolio

PubMed Articles [846 Associated PubMed Articles listed on BioPortfolio]

Ruptured splenic artery aneurysm detected by emergency ultrasound-a case report.

Splenic artery aneurysm is a rare but a potentially fatal condition. It is usually asymptomatic until it ruptures. Here, we present a case of ruptured splenic artery aneurysm in a 59-year-old gentlema...

Matrix remodeling in systemic sclerosis.

Systemic sclerosis (SSc, scleroderma) is an often-fatal disease characterized by connective tissue fibrosis of skin and internal organs. In scleroderma, there is an excessive production and accumulati...

Safety and feasibility of the NanoKnife system for irreversible electroporation ablative treatment of canine spontaneous intracranial gliomas.

OBJECT Irreversible electroporation (IRE) is a novel nonthermal ablation technique that has been used for the treatment of solid cancers. However, it has not been evaluated for use in brain tumors. He...

Human infection with a novel highly pathogenic avian influenza A (H5N6) virus: Virological and clinical findings.

Human severe infection with avian influenza A (H5N6) virus infection was identified firstly in 2014 in China. It was unknown or unclear on the disease or the pathogen by people. This study would illus...

Death matters: understanding heroin/opiate overdose risk and testing potential to prevent deaths.

To describe work undertaken over a 20-year period, investigating overdose characteristics among survivors, effects of acute heroin administration, clustering of risk of overdose fatality and potential...

Fatal tiger shark, Galeocerdo cuvier attack in New Caledonia erroneously ascribed to great white shark, Carcharodon carcharias.

To understand the causes and patterns of shark attacks on humans, accurate identification of the shark species involved is necessary. Often, the only reliable evidence for this comes from the characte...

Macacine Herpesvirus 1 in Long-Tailed Macaques, Malaysia, 2009-2011.

Macacine herpesvirus 1 (MaHV1; B virus) naturally infects macaques (Macaca spp.) and can cause fatal encephalitis in humans. In Peninsular Malaysia, wild macaques are abundant, and translocation is us...

Non-vitamin K antagonist oral anticoagulants and atrial fibrillation guidelines in practice: barriers to and strategies for optimal implementation.

Stroke is a leading cause of morbidity and mortality worldwide. Atrial fibrillation (AF) is an independent risk factor for stroke, increasing the risk five-fold. Strokes in patients with AF are more l...

50 Years Ago in TheJournalof Pediatrics: Fatal Infection in a Newborn Infant Due to Herpes Simplex Virus.

Excessive Video Game Use, Sleep Deprivation, and Poor Work Performance Among U.S. Marines Treated in a Military Mental Health Clinic: A Case Series.

Excessive use of video games may be associated with sleep deprivation, resulting in poor job performance and atypical mood disorders. Three active duty service members in the U.S. Marine Corps were of...

News Articles [496 Associated News Articles listed on BioPortfolio]

Three-pronged approach could reduce suicide risk

"Suicidal thought doesn't need to be fatal to be serious" is the mantra of a University of Queensland expert who has spent five years developing a new mental health test.

Czech tour guide hospitalised with suspected MERS

A Czech tour guide has been hospitalised in Prague, suspected of having the potentially fatal MERS virus, the health minister said Friday.

Tests rule out MERS in Czech tour guide (Update)

Tests have ruled out the potentially fatal MERS virus in a Czech tour guide hospitalised in Prague, the health minister said Friday.

FDA Approves Drug That Eventually Could Help Half of People with Cystic Fibrosis

(The Washington Post) – Federal regulators on Thursday approved a new drug that treats the underlying cause of cystic fibrosis and eventually might be used to help nearly half of the 30,000 pat...

Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001

PALO ALTO, Calif., July 1, 2015 /PRNewswire/ -- Neuraltus Pharmaceuticals, Inc., a privately-held biopharmaceutical company focused on the development of groundbreaking drugs to treat neurod...

Wake UP Happy and Sleep Soundly with Famous Experts with My Wake UP Call® Motivational Alarm Clock® Messages and My Good Night Messages™ - Now Available at Audible!

Malibu, CA (PRWEB) June 30, 2015 Americans report feeling more stressed than ever before. There’s even a documented spike in he...

Heart Fit Clinic Releases External Counterpulsation Therapy To Treat People with Stress and Heart Disease

This economic uncertainty is driving an increased amount of physical stress amongst the workforce as oil and gas companies weather oil's lows since 2008. Now, the Heart Fit Clinic has released Ext...

CTD Holdings Ships Additional Trappsol(R) Cyclo(TM) to Brazil

ALACHUA, FL--(Marketwired - June 30, 2015) - CTD Holdings, Inc. (OTCQB: CTDH), a family of biotechnology growth companies that develop cyclodextrin-based treatments, today announced that the company i...

How small genetic change in Yersinia pestis changed human history

(Northwestern University) While studying Yersinia pestis, the bacteria responsible for epidemics of plague such as the Black Death, scientists found a single small genetic change that fundamentally in...

Targeted Nanoparticles Can Overcome Drug Resistance in Trypanosomes: A High-Tech Approach to Combat Sleeping Sickness and Potentially Other Neglected Diseases

(Nanotechnology Now) – Sleeping sickness, or African trypanosomiasis, is caused by trypanosome parasites transmitted by tsetse flies and threatens millions of people in sub-Saharan Africa. The d...

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Companies [16 Associated Companies listed on BioPortfolio]

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the ...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Akashi Therapeutics, Inc.

Akashi Therapeutics is a clinical stage biopharmaceutical company whose mission is to develop treatments for Duchenne muscular dystrophy and other rare pediatric diseases. ...

Clinical Trials [384 Associated Clinical Trials listed on BioPortfolio]

OCT-Features in Culprit and Not Culprit Coronary Plaque in ACS Patients

The OCT-FORMIDABLE register will include with a retrospective fashion all consecutive patients that perform OCT on culprit and not culprit plaque in any subset in patients with ACS. Clinic...

Prospective Study of Patients With Thrombocytopenia Following HSCT

Isolated thrombocytopenia is a common and severe complication of HSCT, which often leads to an increased risk of life-threatening hemorrhage, frequent requirement of platelet transfusions ...

The Study of Spectrum of Sleep Disorders in Cirrhotic Patients and the Efficacy of Zolpidem in Cirrhotic Patients With Insomnia

50 patients of clinical, radiological, biopsy proven cirrhosis patient will be randomized into cases and control groups after ruling out possibility of psychiatric illnesses like depressio...

Using Ultrasound Elastography to Predict Development of SOS

Sinusoidal obstruction syndrome (SOS) is a potentially fatal hepatic veno-occlusive disease-affecting children following bone marrow transplantation (BMT). SOS most likely develops seconda...

Influence of the Education in Layperson in Out of Hospital Resuscitation

Cardiac arrest occurs frequently and the outcome after out-of-hospital resuscitation is often fatal. Disturbing is that more than half of the surviving patients suffer from permanent impai...

Isoquercetin as an Adjunct Therapy in Patients With Kidney Cancer Receiving First-line Sunitinib

Advanced renal cell carcinoma is invariably fatal, with a life expectancy of 2-3 years since diagnosis. Sunitinib is the standard first-line treatment for this condition, but it is associa...

Circadian Phase Assessments at Home

An estimated 23 million Americans, including adolescents and the elderly, suffer from circadian rhythm sleep disorders, such as delayed sleep phase disorder, advanced sleep phase disorder ...

The Effect of Melatonin Upon Post-Acute Withdrawal Among Males in a Residential Treatment Program

Individuals recovering from drug and/or alcohol addiction initially experience the symptoms of acute withdrawal before experiencing the symptoms of post-acute withdrawal (PAWS). PAWS incl...

Cognitive Behavior Therapy for Insomnia Delivered by a Therapist or on the Internet

Background: Insomnia is a highly prevalent and disabling disorder where Cognitive Behavior Therapy for Insomnia (CBT-I) is established as the best available treatment. Still, only a neglig...

Safety and Efficacy Study of Apixaban to Prevent Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With PEG Asparaginase

To compare the effect of prophylactic oral or enteric apixaban versus no administration of systemic prophylactic anticoagulant during induction chemotherapy, on the composite endpoint of a...

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Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.


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