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Fatal Insomnia - Biotech, Pharma and Life Science Channel

11:56 EST 19th January 2017 | BioPortfolio

PubMed Articles [827 Associated PubMed Articles listed on BioPortfolio]

Lethal Angiostrongylus vasorum infection in a Hungarian dog.

During post-mortem examination of lungs and heart of a 7-month-old female French bulldog, 158 worms were collected from the lung vessels and they proved Angiostrongylus vasorum by their morphological ...

Report of fatal mixed infection with Cryptosporidium parvum and Giardia intestinalis in neonatal calves.

In the production and management of beef and dairy cattle, controlling diarrhea is one of the important concerns. Pathogenic agents of the disease, protozoan parasites including Cryptosporidium spp., ...

Portography: a potentially fatal complication during endoscopic ultrasound-guided choledochoduodenostomy.

The First Infant Death Associated With Human Coronavirus NL63 Infection.

Human coronavirus NL63 (HCoV-NL63) primarily infects the upper respiratory tract. However, it may cause severe lower respiratory tract infection, and the clinical course may be severe in immunocomprom...

Fatal case of rickettsiosis in a toddler from southeastern Mexico.

Rocky Mountain spotted fever is a disease caused by Rickettsia rickettsii, a bacteria transmitted by infected ticks. It is characterized by fever, exanthema, arthralgias and myalgias; but sometimes it...

The role of miR-497-5p in myofibroblast differentiation of LR-MSCs and pulmonary fibrogenesis.

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal fibrotic lung disease characterized by profound changes in stem cell differentiation, epithelial cell phenotypes and fibroblast ...

TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3.

Glioblastoma (GBM) is the most malignant form of primary brain tumor and GBM stem-like cells (GSCs) contribute to the rapid growth, therapeutic resistance and clinical recurrence of these fatal tumors...

Diagnostic open brain biopsy following initial negative results of cerebrospinal fluid assessment for Toxoplasma.

Cerebral toxoplasmosis is a rare but fatal complication after allogeneic hematopoietic stem cell transplantation (HSCT), and reaching an accurate antemortem diagnosis with pathological proof is diffic...

Antidiabetic agents and cardiovascular outcomes in patients with heart diseases.

This article reviews evidence of benefits and risk of antidiabetic agents in cardiovascular (CV) outcomes, with a focus on medications approved by the FDA since 2008. Peer-reviewed articles were ident...

The relationship of perfectionism with psychological symptoms in cancer patients and the contributing role of hyperarousability and coping.

Significant levels of anxiety, depression and insomnia symptoms are found in cancer patients. Perfectionism, arousability and coping have been associated with these psychological symptoms in the gener...

News Articles [617 Associated News Articles listed on BioPortfolio]

Opdivo (nivolumab) Demonstrated Efficacy and Improved Survival in Patients with Previously Treated Advanced Gastric Cancer in a Randomized Phase 3 Study

Opdivo demonstrated a 37% reduction in the risk of death compared to placebo 12-month overall survival rates were 26.6% in Opdivo-treated patients compared to 10.9...

Parent Project Muscular Dystrophy Designates Yale New Haven Children's Hospital, a Certified Duchenne Care Center

HACKENSACK, N.J., Jan. 19, 2017 /PRNewswire-USNewswire/ -- Yale New Haven Children's Hospital's Muscular Dystrophy Program became the 13th clinic named a Certified Duchenne Care Center by Parent ...

New Blood Test Can Predict Outcome for Ebola-Infected Patients

Scientists at the University of Liverpool, in collaboration with Public Health England, Boston University and other international partners, say they used blood samples taken from infected and recoveri...

Tesco recalls thousands of popular curries as they contain ‘deadly’ ingredient not on label – Mirror.co.uk

Mirror.co.ukTesco recalls thousands of popular curries as they contain 'deadly' ingredient not on labelMirror.co.ukSupermarket giant Tesco has cleared shelves of thousands of popular curries as they c...

Teva Receives FDA Approval for VANTRELATM ER (Hydrocodone Bitartrate) Extended-Release Tablets [CII] Formulated with Proprietary Abuse Deterrence Technology

VANTRELA ER label describes the product’s abuse-deterrent properties against abuse in the three most common routes—oral, intranasal and intravenous Teva Pharmaceuti...

Bayer to Present Latest Stivarga Data at ASCO GI 2017

WHIPPANY, N.J., Jan. 18, 2017 /PRNewswire/ -- Bayer announced today that the company will present seven abstracts on Stivarga® (regorafenib) in advanced liver and colorectal cancers at the 2017 ...

Eisai acquires manufacturing rights for API from Roche to treat insomnia

Eisai has acquired the rights for manufacturing active pharmaceutical ingredients (API) for Japan from F Hoffman-La Roche for the insomnia treatment / anaesthesia induction agent flunitrazepam.

New insights in genetic defect allow prevention of fatal illnesses in children

(VIB (the Flanders Institute for Biotechnology)) A team of scientists led by Professor Adrian Liston and Professor Isabelle Meyts were able to characterize a new genetic immunodeficiency resulting fro...

When Mice Attack

By stimulating two separate neuronal pathways, researchers provoke normally timid mice to stalk prey or launch fatal biting attacks. Learn more...

LMS finds AI can predict heart failure – Daily Mail

Daily MailLMS finds AI can predict heart failureDaily MailNewly-unveiled artificial intelligence can predict exactly when patients with a heart disorder will die, scientists claim. Software, developed...

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Companies [17 Associated Companies listed on BioPortfolio]

CurePSP

CurePSP is the leading nonprofit advocacy organization focused on prime of life neurodegenerative diseases – a spectrum of fatal brain disorders that often strike during a pe...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the ...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Clinical Trials [541 Associated Clinical Trials listed on BioPortfolio]

Auricular Acupressure for Hemodialysis Patients With Insomnia

Auricular acupressure therapy (AAT) has been applied in MHD patients with insomnia in recent years and yielded favorable results. However, the effect and safety of AAT for insomnia in MHD ...

BSIP - Better Sleep in Psychiatric Care - ADHD.

Cognitive Behavioral Therapy (CBT) is treatment of choice for insomnia (CBT-i). Many patients in psychiatric care have sleep problems including insomnia, but are rarely given the choice to...

Effects of Leader Sleep Improvement on Leadership

The purpose of our study is to investigate the effects of sleep improvement in leaders on leader outcomes.

Registry of the Combination of Antiplatelet Agents and Anticoagulant in Atrial Fibrillation Patients With a CHA2DS2VASc Score >1 Undergoing Percutaneous Coronary Interventions

Patients undergoing percutaneous coronary intervention (PCI) with stent implantation and requiring chronic anticoagulation for atrial fibrillation (AF) with a CHA2DS2-VASc >1 are required ...

Cardiovascular Impact, Quality e Quantity of Sleep in Bed Partners of Patients With Obstructive Sleep Apnea

Obstructive sleep apnea (OSA) is a common clinical condition associate with a negative impact not limited to the patients but also to the partner that sleep in the same bed. Is it reasonab...

Feasibility and Acceptability of an Internet-based Cognitive-behavioral Treatment for Insomnia

The purpose of the proposed study are to determine if the Internet is a feasible and acceptable delivery method for cognitive-behavioral treatment for insomnia (CBT-I) in adults with asthm...

CBT-I as Early Intervention of Mood Disorders

This study aims to investigate the effectiveness of transdiagnostic nurse-administered 4-session group cognitive behavioral therapy for insomnia (CBT-I) plus standard care, compared to sta...

A Study of Home Monitoring in Adults With Cystic Fibrosis (HOMECF)

Cystic fibrosis (CF) is the most common fatal inherited condition in Caucasians, causing recurrent chest infections and premature death due to lung failure. When patients develop chest inf...

Role of Microparticles in the Coagulopathy of Acute Promyelocytic Leukemia

Although the clinical application of differentiation therapy has made great success in the treatment of acute promyelocytic leukemia (APL), early fatal bleeding remains an unsolved problem...

Sleep to Prevent Evolving Affecting Disorders

The primary objective of the proposed research is to determine the efficacy of Digital Cognitive Behavior Therapy (dCBTI) in preventing the incidence of depression among insomniacs. In add...

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Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

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