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Fatal Insomnia - Biotech, Pharma and Life Science Channel

01:52 EDT 29th July 2016 | BioPortfolio

PubMed Articles [823 Associated PubMed Articles listed on BioPortfolio]

Fatal Case of West Nile Neuroinvasive Disease in Bulgaria.

In Vivo Magnetic Resonance Imaging and Microwave Thermotherapy of Cancer Using Novel Chitosan Microcapsules.

Herein, we develop a novel integrated strategy for the preparation of theranostic chitosan microcapsules by encapsulating ion liquids (ILs) and Fe3O4 nanoparticles. The as-prepared chitosan/Fe3O4@IL m...

Decision support in addiction: The development of an e-health tool to assess and prevent risk of fatal overdose. The ORION Project.

The application of e-health technology to the field of substance use disorders is at a relatively early stage, and methodological quality is still variable. Few have explored the extent of utilization...

Transfusion Related Acute Lung Injury (TRALI): A Single Institution Experience of 15 Years.

Transfusion related acute Lung injury (TRALI) though a serious blood transfusion reaction with a fatality rate of 5-25 % presents with acute respiratory distress with hypoxaemia and noncardiac pulmon...

Application of cellulose acetate for controlled release of thymol.

Cellulose acetate (CA) was investigated as a carrier towards development of material with controlled release of thymol as a natural substance with strong antibacterial properties using high pressure t...

Phosphorylated neurofilament heavy chain levels in paired plasma and CSF of amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by degeneration of both upper and lower motor neurons. In this study, we aimed to measure both plasma and cerebrospinal fluid (CSF)...

Sexual disinhibition and agrypnia excitata in fatal familial insomnia.

Helminth Interaction with the Host Immune System: Short-Term Benefits and Costs in Relation to the Infectious Environment.

Chronic infections imply that the parasite and the host immune system closely interact for a long time without a fatal outcome. Environmental changes encountered by hosts and parasites, such as coinfe...

Fatal Septic Meningitis in Child Caused by Streptococcus suis Serotype 24.

We Made Your Bed, Why Won't You Lie in It? Food Availability and Disease May Affect Reproductive Output of Reintroduced Frogs.

Mitigation to offset the impacts of land development is becoming increasingly common, with reintroductions and created habitat programs used as key actions. However, numerous reviews cite high rates o...

News Articles [644 Associated News Articles listed on BioPortfolio]

Tighten teens' nighttime driving restrictions: CDC

(HealthDay)—Getting U.S. teens out of the driver's seat before midnight would reduce their risk of fatal crashes, federal health officials said Thursday in a new report.

Minerva Neurosciences to Report Second Quarter 2016 Financial Results and Business Updates on August 4, 2016

Management to host conference call WALTHAM, Mass., July 28, 2016 (GLOBE NEWSWIRE) -- Minerva Neurosciences, Inc. (NASDAQ:NERV), a clinical-stage biopharmaceutical company focused on the devel...

In Midst Of Opioid Crisis, Quietly Passed Law Relaxes Rules For Drug Companies

Critics of the legislation say it takes pressure off companies to detect and report drugs flowing to the black market. In other news, after fatal overdoses, advocates say dealers should face punishmen...

Is It Flu, or Is It Valley Fever?

THURSDAY, July 28, 2016 -- Early diagnosis of a potentially fatal fungal infection called valley fever can help patients, but too many are misdiagnosed, experts say. Doctors should suspect valley feve...

Digital start-up gets funding for 'Sleepio'

The latest digital health start-up to get funding in 2016 aims to improve mental health by overcoming poor sleep. London and San Francisco-based Big Health has gained $12 million in a series B fundin...

Acute Respiratory Distress Syndrome patients who smoke, are obese have poorer quality of life

A new study of patients who survive the once-nearly fatal Acute Respiratory Distress Syndrome finds their subsequent quality of life has more to do with lifestyle factors than how sick they were in th...

NCMA’s Dr. James Marco Steele Shares Insights About a New Study Concerning the Hazards of Too Much or Too Little Sleep

Northern California Medical Associate’s Dr. James Marco Steele discusses the importance of getting enough rest and offers some options for people with chronic sleep issues. Santa Rosa, CA (PRWEB) Ju...

This App Is Conquering Insomnia And Depression At The Same Time

The developers behind Sleepio have just raisedanother $12 million to sell their app to more employers in the U.S.

Big Health Raises $12M to Bring Evidence-Based Digital Medicine to Millions

SAN FRANCISCO, CA and LONDON, UNITED KINGDOM -- (Marketwired) -- 07/27/16 -- Digital health company Big Health today announces a new round of $12 million led by Octopus Ventures with Kaiser Permanent...

New study finds ARDS patients who smoke and are obese have poorer quality of life

(Intermountain Medical Center) A new study of patients who survive the once-nearly fatal Acute Respiratory Distress Syndrome finds their subsequent quality of life has more to do with lifestyle factor...

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Companies [17 Associated Companies listed on BioPortfolio]

CurePSP

CurePSP is the leading nonprofit advocacy organization focused on prime of life neurodegenerative diseases – a spectrum of fatal brain disorders that often strike during a pe...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the ...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Clinical Trials [497 Associated Clinical Trials listed on BioPortfolio]

Efficacy and Safety of ACT-541468 in Elderly With Insomnia Disorder

The primary objective of this study is to assess the effect of ACT-541468 on a measure of sleep maintenance (Wake after Sleep Onset or WASO) by polysomnography in elderly subjects with ins...

Efficacy and Safety of ACT-541468 in Adult Subjects With Insomnia Disorder

The primary objective of this study is to assess the effect of ACT-541468 on a measure of sleep maintenance (Wake after Sleep Onset or WASO) by polysomnography in subjects with insomnia di...

Adverse Drug Reactions With Fatal Outcome

The purpose of this study is to determine the incidence of drug-related deaths in a university hospital during the year 2015

Diabetes Complication Control in Community Clinics (D4C) Trial

The overall objective of the proposed cluster randomized trial is to test whether implementation of protocol-based integrated care will improve CVD risk factors (glycated hemoglobin [HbA1C...

Understanding Benzodiazepine and Non-benzodiazepine Sedative Use

Inappropriate medication use among the elderly ranges from 11% to 62% (Guaraldo 2011) and is a major concern for patient safety. Benzodiazepines account for approximately 20 to 25% of inap...

Effect of Transcranial Direct-current Stimulation Therapy on Primary Chronic Insomnia Patients

To evaluate the clinical efficacy and safety of neuromodulation by transcranial direct current stimulation (tDCS) in the patients with primary chronic insomnia .

The Role of Tapering Pace and Selected Traits on Hypnotic Discontinuation

Treatment-seeking insomnia sufferers most often present in primary care venues where the first and usually only treatment is a prescription for a sedative hypnotic, typically a benzodiazep...

Cognitive Behavioral Therapy for Insomnia in Stable Heart Failure

The purpose of this exploratory developmental study is to test the feasibility, acceptability, and preliminary efficacy of cognitive behavioral therapy for insomnia (CBT-I) among adults wh...

The Sleepless Brain: Neuroimaging Support for a Differential Diagnosis of Insomnia

One-tenth of the population suffers from insomnia, increasing their risk on other health problems such as depression. Self-reported sleep quality only was historically leading for insomnia...

A Study to Compare Administration Schedules of G-CSF (Filgrastim) for Primary Prophylaxis of Chemotherapy-Induced Febrile Neutropenia in Early Stage Breast Cancer (REaCT-G2)

In patients with early-stage breast cancer, chemotherapy has substantially improved survival rates. Improvements in outcomes, however, are compromised by the considerable toxicities associ...

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Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

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