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Fatal Insomnia - Biotech, Pharma and Life Science Channel

10:12 EDT 27th May 2016 | BioPortfolio

PubMed Articles [835 Associated PubMed Articles listed on BioPortfolio]

Application of cellulose acetate for controlled release of thymol.

Cellulose acetate (CA) was investigated as a carrier towards development of material with controlled release of thymol as a natural substance with strong antibacterial properties using high pressure t...

Anaphylaxis after administration of amikacin containing sodium metabisulfite in a premature newborn.

Anaphylaxis is a serious systemic hypersensitivity reaction that is rapid in onset and can cause death. Premature newborns, whose immunological system is immature, are less likely to develop anaphylax...

Avoiding Severe Toxicity From Combined BRAF Inhibitor and Radiation Treatment: Consensus Guidelines from the Eastern Cooperative Oncology Group (ECOG).

BRAF kinase gene V600 point mutations drive approximately 40% to 50% of all melanomas, and BRAF inhibitors (BRAFi) have been found to significantly improve survival outcomes. Although radiation therap...

Frequency of health service use in the year prior to asthma death.

High frequency health service use (HSU) is associated with poorly controlled asthma, and is a recognized risk factor for near-fatal or fatal asthma. The objective of this study was to describe the fre...

Hepatitis B Virus Reactivation in the Setting of Cancer Chemotherapy and Other Immunosuppressive Drug Therapy.

Hepatitis B virus reactivation (HBVr) is an important complication of immunosuppressive drug therapy (ISDT). It can occur with active or resolved hepatitis B virus (HBV) infection with a clinical spec...

A Self-Administered Sleep Intervention for Patients With Cancer Experiencing Insomnia.

Sleep-wake disturbances are experienced by as many as 75% of patients with cancer and are associated with poor symptom management, lower functionality, and decreased quality of life. Although promisin...

Diagnosis and Management of Coagulopathy-Related Intracerebral Hemorrhage.

Coagulopathy, defined as impaired clot formation, is common in intensive care units (ICUs). Many physiological derangements lead to dysfunctional hemostasis in the ICU; most of these are acquired rath...

Great nature's second course: Introduction to the special issue on the behavioral neuroscience of sleep.

Sleep is necessary for normal psychological functioning, and psychological function in turn affects sleep integrity. Recent investigations delineate the relation of sleep to a broad array of processes...

Mitochondrial Haplogroups and Risk of Pulmonary Arterial Hypertension.

Pulmonary arterial hypertension (PAH) is a serious and often fatal disease. It is a panvasculopathy of the pulmonary microcirculation characterized by vasoconstriction and arterial obstruction due to ...

Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition.

Pathogens hide immunogenic epitopes from the host to evade immunity, persist and cause infection. The opportunistic human fungal pathogen Candida albicans, which can cause fatal disease in immunocompr...

News Articles [579 Associated News Articles listed on BioPortfolio]

Braeburn Pharmaceuticals Announces FDA Approves Probuphine® (buprenorphine) Implant: The First Implant for Treatment of Opioid Dependence

PRINCETON, N.J., May 26, 2016 /PRNewswire/ -- Braeburn Pharmaceuticals announces that the U.S. Food & Drug Administration (FDA) approved Probuphine, the first implant for the maintenance trea...

Voluntary Recall On Certain Backroad Country Brand Sunflower Kernel Products

Millersburg, OH - Troyer Cheese Inc, under advice from its packaging facility concerning, CRANBERRY NUT DELIGHT MIX PREPACK, HONEY ISLAND CRUNCH MIX PREPACKAGED, PRETZELS PEANUT BUTTER PREPACKAGED, a...

Health risks for female sex workers and their children

(Reuters Health) - Many female sex workers and their children have unmet needs for medical care, which puts them at risk for serious and potentially fatal health problems, some researchers argue.

Telephone-Based CBT Improves Menopause-Related Insomnia

Insomnia decreased while other sleep measures improved after 8 weeks of cognitive behavioral therapy for insomnia in both premenopausal and postmenopausal women. Medscape Medical News

How prions kill neurons: New culture system shows early toxicity to dendritic spines

(PLOS) Prion diseases are fatal and incurable neurodegenerative conditions of humans and animals. Yet, how prions kill nerve cells (or neurons) remains unclear. A study published on May 26, 2016 in PL...

France Tightens Rules in Wake of Fatal Clinical Trial

(Science) – The French government is taking measures to lower the health risks to volunteers in clinical trials in the wake of the final report about a study that killed one person and landed fi...

EMA reportedly reviewing clinical guidelines in wake of fatal drug trial

A report from French regulators concluded Portuguese drugmaker Bial and CRO Biotrial made several key mistakes in a January trial which left one man dead and hospitalized five others. 

High Uric Acid Increases Risk of Non-Fatal Stroke in CKD Patients

Odds of non-fatal stroke are 49% higher in patients in the fourth quartile of uric acid level versus those in the second quartile.

Breakthrough Could Help Sufferers of Deadly Lung Disease

Pioneering research conducted by the University of Sheffield is paving the way for new treatments which could benefit patients suffering from the fatal lung disease pulmonary arterial hypertension (PA...

Hickory Harvest Expands Recall of Certain Sunflower Kernel Products Because of Possible Listeria Monocytogenes

Hickory Harvest Foods, under advice from its sunflower kernel supplier, SunOpta, is expanding their recall of a limited number of products that have the potential to be contaminated with Listeria mono...

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Companies [17 Associated Companies listed on BioPortfolio]

CurePSP

CurePSP is the leading nonprofit advocacy organization focused on prime of life neurodegenerative diseases – a spectrum of fatal brain disorders that often strike during a pe...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Ario Pharma Ltd

ario pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1...

Agilis Biotherapeutics, LLC

Agilis Biotherapeutics, LLC, is a biotechnology company focused on designing and engineering first-in-class DNA-based therapeutics to improve and save the lives of patients affect...

Edge Therapeutics, Inc.

Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...

Takeda Pharmaceuticals U.S.A., Inc. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Global Research & Development Center, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the ...

Takeda Pharmaceuticals U.S.A. and Affymax, Inc.

Based in Deerfield, Ill., Takeda Pharmaceuticals U.S.A., Inc. and Takeda Development Center Americas, Inc. are subsidiaries of Takeda Pharmaceutical Company Limited, the largest p...

Oxyrane UK Limited

WHO WE ARE Oxyrane UK Limited is a biopharmaceutical company dedicated to the development of novel and biosuperior enzyme replacement therapies (ERT) to treat lysosomal storage diseases, a class o...

Alpha-Stim

Alpha-Stim is an industry leader in cranial electrotherapy stimulation (CES) devices, providing treatment for anxiety, depression, insomnia and pain, without the side effects comm...

Janssen Alzheimer Immunotherapy

Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...

Clinical Trials [477 Associated Clinical Trials listed on BioPortfolio]

Study of the Efficacy and Safety of Lemborexant in Subjects 55 Years and Older With Insomnia Disorder

The primary objective of this study is to demonstrate using polysomnography (PSG) that 10 mg lemborexant is superior to zolpidem tartrate extended release 6.25 mg (Ambien CR®) on objectiv...

Behavioral Sleep Intervention in Children With Disruptive Behaviors

Despite the high prevalence of sleep difficulties in children with disruptive behavior disorders, little is known about the role of sleep in treating disruptive behavior. The current study...

Insomnia Interventions in Cancer Survivors

This study looks at two different interventions used for the treatment of insomnia in survivors of breast, colon, lung, prostate and gynecologic cancer.

Cognitive Behavioral Therapy for Insomnia for Gulf War Illness

Sleep disturbance is a common complaint of Veterans with Gulf War Illness (GWI). Because there is clinical evidence that sleep quality influences pain, fatigue, mood, cognition, and daily ...

Tongue Protrusion Force: A Pilot Study

From Weill Cornell Medical College Center for Sleep Medicine, we will recruit patients (N = 25) with previously documented moderate to severe OSA. They will receive an all-night in-home sl...

Infant Night Wakings in Pediatric Primary Care

This study aims to: 1. identify which single item or combination of two items perform best in identifying problematic infant night wakings and 2. describe current practice...

Integrative Cardiac Health Project Cognitive-Behavior Therapy for Insomnia

This study investigates the feasibility, acceptability, and effectiveness of adding Cognitive-Behavioral Therapy for Insomnia (CBT-I) to the standard care received at the Integrative Cardi...

Treatment With Benzodiazepine After Cardiac Surgery

The study deals with the prevalence of insomnia after heart surgery and the outcome of treatment with Benzodiazepine for this phenomena.

Treatment of Comorbid Sleep Disorders and PTSD

The primary objective of the current study is to determine if providing cognitive-behavloral therapy of Insomnia and nightmares (CBTl&N) and Cognitive Processing Therapy of PTSD (CPT) resu...

Dendritic Cell-Based Tumor Vaccine Adjuvant Immunotherapy of Human Glioblastoma Multiforme (WHO Grade IV Gliomas)

Purposes: The purpose of this phase-II clinical trial is to determine whether or not ADCTA-G, a biologic "vaccine" preparation of patient's own dendritic cell (DC) for glioblastoma ...

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Medical and Biotech [MESH] Definitions

An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomnia. It is caused by a mutation in the prion protein (PRIONS).

An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.

A hypnotic and sedative used in the treatment of INSOMNIA.

A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

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