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Fatty Liver - Biotech, Pharma and Life Science Channel

20:49 EDT 22nd May 2013 | BioPortfolio

PubMed Articles [ 8318 Associated PubMed Articles listed on BioPortfolio]

Molecular alterations in proteasomes of rat liver during aging result in altered proteolytic activities.

Aging induces alterations of tissue protein homoeostasis. To investigate one of the major systems catalysing intracellular protein degradation we have purified 20S proteasomes from rat liver of young...

Antenna design and tissue parameters considerations for an improved modelling of microwave ablation in the liver.

Microwave ablation is a technique used in treating hepatocellular carcinoma, especially in cases where surgical removal is impossible. In the present study we are investigating the effects of design c...

The ALPPS technique for bilateral colorectal metastases: three "variations on a theme"

The aim of this study was to assess feasibility of technical variations of the associating liver partition and portal vein ligation for staged hepatectomy technique (ALPPS) with regard to three differ...

Non-Esterified Fatty Acids Activate the AMP-Activated Protein Kinase Signaling Pathway to Regulate Lipid Metabolism in Bovine Hepatocytes.

Non-esterified fatty acids (NEFAs) act as signaling molecules involved in regulating genes expression to modulate lipid metabolism. However, the regulation mechanism of NEFAs on lipid metabolism in da...

Time Trends in Liver Cancer Mortality, Incidence, and Risk Factors by Unemployment Level and Race/Ethnicity, United States, 1969-2011.

This study examined unemployment and racial/ethnic disparities in liver cancer mortality, incidence, survival, and risk factors in the United States between 1969 and 2011. Census-based unemployment ra...

Alishewanella solinquinati sp. nov., Isolated from Soil Contaminated with Textile Dyes.

A novel Gram-negative, motile, rod-shaped, facultative anaerobic bacterial strain, KMK6(T), was isolated from soil contaminated with textile dyes from an industrial estate located at Ichalkaranji, Mah...

Tissue Distribution of Metals in White-fronted Geese and Spot-Billed Ducks from Korea.

This study presents concentrations of Fe, Zn, Mn, Cu, Pb and Cd in livers, kidneys, muscles and bones of white-fronted geese Anser albifrons (geese) and spot-billed ducks Anas poecilorhyncha (ducks)....

Prospective phase II study of neoadjuvant FOLFOX6 plus cetuximab in patients with colorectal cancer and unresectable liver-only metastasis.

PURPOSE: Liver resection may offer the only chance of cure in patients with colorectal cancer with liver metastases. In the unresectable cases, neoadjuvant chemotherapy could render curability if rese...

Review: Replacing dietary saturated fatty acids with n-6 polyunsaturated fatty acids does not reduce mortality.

Functional specific roles of FADD: comparative proteomic analyses from knockout cell lines.

Fas-associated death domain (FADD) is a classical adaptor protein involved in tumor necrosis factor receptor family-mediated apoptosis. Besides being an essential instrument in cell death, it also pla...

News Articles [ 2802 Associated News Articles listed on BioPortfolio]

NAFLD Contributes to Hepatocarcinogenesis

Does the latest research show that NAFLD could be responsible for hepatocellular carcinoma in patients with non-cirrhotic liver disease? Journal of Gastroenterology and Hepatology

Vet Supply Source Brings Relief to People With Pet Allergies

Vet Supply Source has a few products that could help people with pet allergies breathe a little easier this summer. Vet Supply Source carries HealthyCoat, a fatty supplement that would greatly reduce...

Bioartificial Liver Project Looks to Disposable Bioreactors for Large Scale Cultures

Disposable bioreactors could be the centerpiece of a project to develop and harvest large quantities of cells that eventually will be used in bioartificial livers for patients with severe liver failur...

Sudden Purpuriform Rash in an Infant Sudden Purpuriform Rash in an Infant

A 10-month-old boy presents with erythematous swelling of bothears and right eyelid and erythematous perioral macules following a respiratory tract infection 12 days before presentation (Figure, A). W...

Fish oil may help the heart beat mental stress

(American Physiological Society) Why is fish oil good for the heart? A new study suggests that this omega 3 fatty acid-rich nutrient could blunt some cardiovascular effects of mental stress.

MicroRNAs in liver disease

This Review summarizes current knowledge on the role of different microRNAs (miRNAs) in liver diseases. The functions of the most relevant miRNAs that have specific roles in liver damage, hepatocyte f...

Alnylam to Webcast Presentation at Deutsche Bank 38th Annual dbAccess Health Care Conference

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, today announced that management will present a company overview at the Deutsche Bank 38th...

Low Potassium Linked with Liver Disease (CME/CE)

(MedPage Today) -- Patients with non-alcoholic fatty liver disease also had low potassium levels, researchers in China found.

Baby Boomers Urged to Get Tested for Hepatitis C Virus

KANSAS CITY, Mo., May 21, 2013 /PRNewswire-USNewswire/ -- If you're a baby boomer, you may not know that odds are high that you're carrying the hepatitis C virus, putting yourself at risk for illness...

Veran Medical Introduces vSupport™ Face-to-Face Virtual Support for Electromagnetic Navigation Customers

PHILADELPHIA, May 21, 2013 /PRNewswire/ -- Veran announced today at the American Thoracic Society International Conference that they are partnering with SpotOn Surgical to launch vSupport™ face-...

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Companies [ 32 Associated Companies listed on BioPortfolio]

Transgene SA

Transgene (NYSE-Euronext: TNG), a member of the Institut Mérieux Group, is a biopharmaceutical company. It creates, develops and manufactures targeted immunotherapeutics for th...

Provectus Pharmaceuticals, Inc.

Provectus Pharmaceuticals specializes in developing oncology and dermatology therapies. Its lead oncology agent, PV-10, is designed to selectively target and destroy cancer cells...

Alliqua, Inc.

Alliqua, Inc. (“Alliqua”), formerly HepaLife Technologies, Inc., (OTCBB: HPLF) (FWB: HL1), is an advanced biomedical products company focused on the development and manu...

Pure Inventions

Pure Inventions was founded in 2003 by Certified Clinical Nutritionists and Nutritional Consultants, Lynne Gerhards and Lori Mulligan. The comprehensive line of liquid extracts wa...

Infinity Pharmaceuticals, Inc.

Infinity is an innovative drug discovery and development company seeking to discover, develop, and deliver to patients best-in-class medicines for difficult-to-treat diseases. Inf...

Galectin Therapeutics, Inc.

Galectin Therapeutics (OTC: GALT) is developing promising carbohydrate-based therapies for fibrotic liver disease and cancer based on the Company’s unique understanding of ga...

Jewish Hospital and University of Louisville

Jewish Hospital, a part of KentuckyOne Health, is an internationally renowned high-tech tertiary referral center developing leading-edge advancements in hand and microsurge...

Thermedical

Based in Somerville, Mass., Thermedical is a privately held company founded by Michael G. Curley, Ph.D., and Patrick S. Hamilton, Ph.D. Under multiple National Institutes...

Sucampo Pharmaceuticals, Inc. and Takeda

Sucampo Pharmaceuticals, Inc., an international pharmaceutical company, is focused on the discovery, development and commercialization of proprietary drugs based on prostones. The...

Sucampo Pharmaceuticals, Inc. and Takeda Pharmaceuticals U.S.A., Inc.

Sucampo Pharmaceuticals, Inc. is a global pharmaceutical company focused on innovative research, discovery, development and commercialization of proprietary drugs based on proston...

Clinical Trials [ 1410 Associated Clinical Trials listed on BioPortfolio]

Positron Emission Tomography (PET) to Study Brain Signaling

This study uses positron emission tomography (PET) to examine brain function and signaling involving phospholipids, and to see how signaling is related to blood flow. Much of the brain is...

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010 AM1)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

Omega-3 Fatty Acids in Autism Spectrum Disorders

This is a 12-week open label trial to evaluate whether omega-3 fatty acids is effective in reducing the severity of autism and its comorbidities.

The Effect of Exercise Intervention on Insulin Resistance in Non-alcoholic Fatty Liver Disease (NAFLD)

This project examines the effects of a 4 month structured exercise intervention program in patients with non-alcoholic fatty liver disease (NAFLD). We will examine changes in total and dep...

Dose Escalation Study Combining Oral Capecitabine (Xeloda) and Radiotherapy for Patients With Unresectable Liver or Cholangiocarcinoma

Our long-term working hypothesis is that if 3-D radiation is combined with the effect of capecitabine one hopes to see improved and durable tumor response and survival with acceptable toxi...

HRN 004- Peginterferon a-2a Plus Ribavirin for Chronic Hepatitis C Infection in HIV Infected Persons Who Have Failed to Achieve a Sustained Virologic Response Following Previous Interferon Therapy

Objectives: Primary To evaluate the safety, tolerability, and efficacy of Peginterferon a-2a plus Ribavirin for the treatment of chronic hepatitis C (CHC) infection in persons co-infected...

Study for the Treatment of Significant Steatosis With Xenical Followed by Treatment of Hepatitis C With Pegasys/Copegus

This is a prospective, multi-center, randomized, placebo-controlled trial in subjects with histological evidence of > 33% hepatic steatosis or nonalcoholic steatohepatitis (NASH) and chron...

Lactate Metabolism Study in HIV Infected Persons

Lactic acidosis is a potentially life-threatening disease associated with the treatment of chronic HIV infection. Although acidosis is rare, hyperlactatemia is common and may have long ter...

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combination With Chemotherapy With/Without Bevacizumab for Hepatic Metastases From Colorectal Cancer

The purpose of this study is to determine whether the addition of bevacizumab, to hepatic arterial therapy with floxuridine (FUDR) and dexamethasone (Dex) (regional chemotherapy), and eith...

Acute Normovolemic Hemodilution Versus Standard Intraoperative Management in Patients Having Hepatic Resection and Pancreaticoduodenectomy

With a major liver or pancreas operation, there is a chance that one will require a transfusion of blood products (either red blood cells or plasma). This may be necessary during the oper...

Medical and Biotech [MESH] Definitions

Adenine Nucleotide Translocator 3

A subtype of mitochondrial ADP, ATP translocase found primarily in the LIVER.

Streptococcus Intermedius

A species of gram-positive bacteria in the STREPTOCOCCUS MILLERI GROUP. It is commonly found in the oropharynx flora and has a proclivity for abscess formation, most characteristically in the CENTRAL NERVOUS SYSTEM and LIVER.

Mastocytosis, Systemic

A group of disorders caused by the abnormal proliferation of MAST CELLS in a variety of extracutaneous tissues including bone marrow, liver, spleen, lymph nodes, and gastrointestinal tract. Systemic mastocytosis is commonly seen in adults. These diseases are categorized on the basis of clinical features, pathologic findings, and prognosis.

Receptor, Epha1

The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producing human hepatocellular carcinoma cell line and is highly conserved among many mammalian species. Overproduction of the EphA1 receptor is associated with tumors and tumor cells of epithelial origin. It is also expressed at high levels in LIVER; LUNG; and KIDNEY; which is in contrast to many other members of the Eph receptor that are found primarily in tissues of the nervous system.

Asialoglycoprotein Receptor

A C-type lectin that is a cell surface receptor for ASIALOGLYCOPROTEINS. It is found primarily in the LIVER where it mediates the endocytosis of serum glycoproteins.

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