Fetal genetic diagnostic tests - Biotech, Pharma and Life Science Channel
PubMed Articles
The influence of genetic polymorphisms in MDR1 gene on breast cancer risk factors in Chinese.
Breast cancer (BC) is the most common cancer among women in the world. The human multidrug resistance 1 gene (MDR1) is potentially an important gene influencing the susceptibility to breast cancer. Th...
Diagnostic and prognostic significance of CA IX and suPAR in gastric cancer.
This study was intended to evaluate the prognostic and diagnostic significance of carbonic anhydrase IX (CA IX) and soluble urokinase plasminogen activator receptor (suPAR) levels in gastric cancer pa...
Diagnostic value of mesothelin in pleural fluids: comparison with CYFRA 21-1 and CEA.
CYFRA 21-1 and CEA have been applied for the differential diagnosis of malignant pleural mesothelioma (MPM). The soluble mesothelin-related peptide (SMRP) has been proposed as a specific marker for di...
Of marsupials and men: "Backdoor" dihydrotestosterone synthesis in male sexual differentiation.
Following development of the fetal bipotential gonad into a testis, male genital differentiation requires testicular androgens. Fetal Leydig cells produce testosterone that is converted to dihydrotest...
BACKGROUND: Four genes responsible for pseudohypoaldosteronism type II (PHA-II) have been identified, thereby facilitating molecular diagnostic testing. CASE-DIAGNOSIS/TREATMENT: A 1-year-old boy with...
Genomics in cardiovascular disease.
A paradigm shift toward biology occurred in the 1990s and was subsequently catalyzed by the sequencing of the human genome in 2000. The cost of deoxyribonucleic acid (DNA) sequencing has gone from mil...
Modeling the effect of cell division on genetic oscillators.
Many genetic oscillators (circadian clocks, synthetic oscillators) continue to oscillate across the cell division cycle. Since cell divisions create discontinuities in the dynamics of genetic oscillat...
Laboratory tests during direct oral anticoagulant treatment? Yes.
Laboratory tests during direct oral anticoagulant treatment? No.
A 61-year-old man with factor V Leiden thrombophilia presented with hemorrhage and transverse sinus thrombosis (figure, A). Four years later, he developed worsening aphasia, new hemorrhage, and hemisp...
News Articles
Abbott aids Epizyme in matching epigenetic drug with cancer patients
April 18, 2013 - Abbott plans to develop a companion diagnostic test for an experimental leukemia drug from the biotech startup Epizyme.
Corgenix partners with Eli Lilly to develop diagnostic technology
Corgenix Medical has collaborated with Eli Lilly to develop diagnostic technology that supports the latter's oncology pipeline program.
University Services Announces Expansion of its pm-Assist® Sleep Scoring & Interpretation Service
University Services’ pm-Assist® service now offers additional opportunities to medical professionals and insurance companies including diagnostic pathway determination, shipping of home sleep t...
Corgenix to collaborate with Eli Lilly for diagnostic technology development
Specialized diagnostic kits manufacturer Corgenix has signed an agreement with Eli Lilly and Company, a US-based pharmaceutical company, to develop diagnostic technology in support of a Lilly oncology...
American Clinical Solutions Adds Ritalin to Their Drug Test Panel
Boca Raton, FL, May 23, 2013 --(PR.com)-- American Clinical Solutions now offers drug tests for both methylphenidate and ritalinic acid in urinary or oral fluid samples. Ritalin (methylphenidate) is...
Texas lawmakers OK drug tests for some unemployment applicants
AUSTIN, Texas (Reuters) - Texas came a step closer to requiring some applicants for unemployment benefits to first undergo drug testing, when lawmakers gave final approval to a Republican-backed bill...
Researchers find that over 40% of patients treated for COPD did not actually have the disease
More than 40 percent of patients being treated for COPD at a federally funded clinic did not have the disease, researchers found after evaluating the patients with spirometry, the diagnostic "gold sta...
Iodine Deficiency In Pregnant Women May Harm Babies' IQs
Iodine deficiency during pregnancy may have a negative effect on babies' mental development, according to new research published in The Lancet. Iodine is ingested mainly through dairy products and sea...
In recent years, new medical knowledge has raised concerns about the safety of radiation used in some medical diagnostic imaging tests. But until now, a program to accurately meas...
Events
Select Biosciences' 4th annual Single Cell Analysis Summit 2013 will build on the overwhelming success of the previous Single Cell events.
Welcome to Molecular Medicine Congress and exhibition.
Welcome to AgriGenomics World Congress 2013.
Companies
From its establishment in 1977, simply as a Distributor of diagnostic products, IDS has become a globally-recognised innovator and marketeer in the IVD industry.The Company is particularly well-known...
Foundation Medicine is dedicated to the development of comprehensive tests that will help physicians personalize cancer treatment for their patients. Foundation Medicineâs la...
Eutropics Pharmaceuticals Inc.
Eutropics is addressing the need for improving the treatment of aggressive forms of leukemia, myeloma, lymphoma, and other cancers. The company is developing a novel diagnostic te...
Health Discovery Corporation is a molecular diagnostics company that uses advanced mathematical techniques to analyze large amounts of data to uncover patterns that might otherwis...
HIT creates, distributes and supports market-leading healthcare information technology solution. The company's flagship product, Notifi®, provides enterprise-wide communications of critical and signi...
With the advent of new technologies, in the last four years, DNA sequencing has gone through a technological revolution which has completely changed the market. While in 2007 it still cost over 10 m...
ERBA Diagnostics, Inc. (www.erbadiagnostics.com), headquartered in Miami, Florida, is a fully integrated in vitro diagnostics company that develops, manufactures and distributes i...
Trice is pioneering Needle Based Diagnostic and Therapeutic Technologies for Orthopedics. The companyâs Micro Vision Solutions enable definitive and convenient surgical-grade...
GenMark, a provider of automated, multiplex molecular diagnostic testing systems, detects and measures DNA and RNA targets to diagnose disease and to optimize the treatment of pat...
ScottCare develops high quality diagnostic monitoring, CRM data management, cardiopulmonary rehabilitation, and EHR data integration solutions for hospitals and cardiology practic...
Clinical Trials
Pamidronate to Treat Osteogenesis Imperfecta in Children
This study will evaluate the effect of pamidronate-a drug that decreases bone resorption (breakdown)-on osteogenesis imperfecta. This is a genetic disorder of collagen, the major protein...
Pelvic Pain in Women With Endometriosis
This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus. Standa...
Screening Evaluation for Women With Postpartum Depression
This study evaluates the relationship between mood changes and hormones in women with postpartum depression (PPD). This is an observational study; volunteers who participate will not rece...
Brain Peripheral Benzodiazepine Receptors in Patients With Multiple Sclerosis
This study will use positron emission tomography (PET) to measure a brain protein called peripheral benzodiazepine receptor (PBR) in patients with multiple sclerosis. PBR is created during...
Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression
Background: - Atherosclerosis (thickening of the artery walls caused by cholesterol and other deposits) commonly occurs in the heart vessels and carotid (neck) arteries of adults. This i...
Marinobufagenin as a Target for DIGIBIND in Preeclampsia
Background: - Preeclampsia is a combination of high blood pressure and other potentially life-threatening symptoms. Preeclampsia occurs in up to 10% of pregnancies and is a...
Gene Expression in Cumulus Cells to Predict Pregnancy
The purpose of this study is to determine the performance of a genetic assay, GemART, in cumulus cells predictive of embryo viability, and pregnancy success in women undergoing in vitro fe...
1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain
We will conduct a 12-week, randomized open label study, comparing usual care (UC) antipsychotic treatment (aripiprazole, quetiapine, risperidone) with ziprasidone (ZIP) in children and ado...
This study will evaluate whether the drug mifepristone can improve the symptoms of Cushing's syndrome in people with ectopic adrenal corticotrophin hormone (ACTH) secretion. Cushing's synd...
patients who had failed previous H. pylori eradication on standard triple therapy were randomized into two regimens: 1, esomeprazole (20 mg b.i.d), tripotassium dicitrate bismuthate (300 m...
Videos
How to understand prenatal testing and genetic screening
http://www.howdini.com/howdini-video-7073436.html How to understand prenatal testing and genetic screening Every pregnant woman getting proper medical care w...
Medical and Biotech [MESH] Definitions
Dna Shuffling
The use of DNA recombination (RECOMBINATION, GENETIC) to prepare a large gene library of novel, chimeric genes from a population of randomly fragmented DNA from related gene sequences.
Duty To Recontact
The ethical and/or legal obligation of a health provider or researcher to communicate with a former patient or research subject about advances in research relevant to a treatment or to a genetic or other diagnostic test provided earlier, or about proposed new uses of blood or tissue samples taken in the past for another purpose.
Fetal Research
Experimentation on, or using the organs or tissues from, a human or other mammalian conceptus in the postembryonic period, after the major structures have been outlined. In humans, this corresponds to the period from the third month after fertilization until birth.
Maternal-fetal Relations
The bond or lack thereof between a pregnant woman and her FETUS.
Heterogeneous-nuclear Ribonucleoprotein K
A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.
