Fibromyalgia - Biotech, Pharma and Life Science Channel
FMS (fibromyalgia syndrome) is a widespread idiopathic musculoskeletal pain and fatigue disorder, which is chronic. The pain comes from connective tissues, such as muscles, tendons, and ligaments, but not joints and patients describe it as an ache all over.
The main symptoms of FM are pain and fatigue, but patients can also have a number of associated syndromes; sleep disorders, IBS,
chronic headaches, Temporo-mandibular Joint Dysfunction Syndrome, Multiple Chemical Sensitivity Syndrome and many others.
Although idiopathic, the following events could act as triggers for FM; an infection (viral or bacterial), an accident or the development of another disorder, such as Rheumatoid arthritis, lupus, or hypothyroidism. Other abnormalities that may be implicated are alterations in neurotransmitter regulation (particularly serotonin and noradrenaline, and substance P), immune system function, sleep physiology, and hormonal control.
With the lack of pathophysiological knowledge about FM, it is treated symptomatically. Medications try to improve the quality of sleep, and reducing pain. Alternative approaches include acupuncture, acupressure, nutrition, relaxation techniques, osteopathic manipulation, chiropractic care, therapeutic massage, or a gentle exercise program. Exercise is also recommended, along with a carefully controlled diet. FM carries an annual direct cost of care over $20 billion.
Source; Adapted from UK Fibromyalgia
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PubMed Articles
BACKGROUND: Patients with fibromyalgia (FM) experience pain as well as deficits in positive affect and social relations that are not explicitly addressed in most behavioral treatments. PURPOSE: The pu...
Effects of 15 consecutive cryotherapy sessions on the clinical output of fibromyalgic patients.
Fibromyalgia is a chronic widespread pain disorder in which, the neurogenic origin of the pain, featured by allodynia and hyperalgesia, results from an imbalance in the levels of neurotransmitters and...
Abstract Objective: To compare changes in healthcare resource utilization and costs among members with painful diabetic peripheral neuropathy (pDPN), postherpetic neuralgia (PHN), or fibromyalgia (FM)...
Short-term improvement following dry needle stimulation of tender points in fibromyalgia.
The purpose of this study was to evaluate the short-term efficacy of dry needling therapy in patients severely affected by fibromyalgia. One hundred and twenty fibromyalgia patients were randomly divi...
Is fibromyalgia a cause of failure in the treatment of a painful shoulder?
PURPOSE: This study aims to review the incidence of fibromyalgia in a cohort of patients who were treated for shoulder pain and address whether a concomitant fibromyalgia could have had detrimental ef...
Urinary albumin, protein excretion and circadian blood pressure in patients with fibromyalgia.
Recent evidence suggests that patients with fibromyalgia (FM) have increased oxidative stress, inflammation, endothelial dysfunction and autonomic dysfunction. These factors are also shown to be respo...
Background: Primary fibromyalgia syndrome (FMS) is associated with substantial psychiatric comorbidity. The aim of the present study was to investigate the interrelationship between self-reported symp...
BACKGROUND: No data were available on demographic and clinical characteristics of members of fibromyalgia syndrome (FMS) self-help groups in Germany. MATERIAL AND METHODS: The study was carried out fr...
GH/IGF1 axis disturbances in the fibromyalgia syndrome: is there a rationale for GH treatment?
Fibromyalgia Syndrome (FMS) is a frequent idiopathic condition in which patients experience intense pain in specific tender points, profound fatigue and sleep disturbances. Although pain had not accou...
Fibromyalgia syndrome (FMS) is a widespread musculoskeletal pain condition with unclear physiologic mechanisms. The purpose of this investigation was to compare the responsiveness of nociceptive flexi...
News Articles
Allsup Observes May as Arthritis Awareness Month
Arthritis affects more than 21 million Americans; Allsup representatives can assist individuals with arthritis in applying for Social Security Disability Insurance benefits. Belleville, Ill. (PRWEB) M...
Fibromyalgia Guidelines Trigger Changes for FPs
Fibromyalgia diagnosis does not need extensive testing, treatment includes drug and nondrug therapies, and FM symptoms are easily faked, sometimes for financial gain, Canadian guidelines say. Medsca...
Strong genetic component of fibromyalgia suggested
(HealthDay)—A genome-wide linkage scan has identified the chromosome 17p11.2-q11.2 region as the susceptibility locus for fibromyalgia, according to research published in the April issue of Arthriti...
Fibromyalgia patients 'may benefit from creatine supplementation'
People with fibromyalgia may benefit from taking creatine supplements, a small new study has found. Creatine is a nitrogenous organic acid used by athletes to improve high-intensity training and explo...
Report reveals poor physical activity adherence among people with arthritis
The majority of people with arthritis do not do enough walking, according to a study in the US.Published by the Centres for Disease Control and Prevention (CDC), the report looks at the prevalence of...
Fibromyalgia Treatment: New Canadian Guidelines
Physicians from the McGill University Health Centre (MUHC) and the University of Calgary have published a review article in the CMAJ (Canadian Medical Association Journal) to help family doctors diagn...
Fibromyalgia Awareness Day Sunday, May 12, 2013 and throughout the month of May http://www.fmcpaware.org/ The National Fibromyalgia & Chronic Pain Association (NFM...
Researchers publish new Canadian guidelines for diagnosis and treatment of fibromyalgia
Physicians from the McGill University Health Centre (MUHC) and the University of Calgary have published a review article in the CMAJ (Canadian Medical Association Journal) to help family doctors diagn...
In People With Fibromyalgia, Pain Is Not Worsened By Regular, Moderate Exercise
For many people who have fibromyalgia, even the thought of exercising is painful. Yet a new study from Wake Forest Baptist Medical Center shows that exercise does not worsen the pain associated with t...
New Canadian guidelines for treating fibromyalgia
Physicians from the McGill University Health Centre (MUHC) and the University of Calgary have published a review article in the CMAJ (Canadian Medical Association Journal) to help family doctors diagn...
Events
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Companies
National Fibromyalgia & Chronic Pain Association
NFMCPA, a not-for-profit organization, supports individuals living with fibromyalgia and other chronic pain illnesses by raising awareness through community outreach, education, a...
Premier Biomedical, Inc. is a research-based company that intends to discover and develop medical treatments for humans, specifically targeting the treatment of Alzheimer's Diseas...
TONIX Pharmaceuticals is developing new treatments for challenging disorders of the central nervous system. The Companyâs most advanced program targets fibromyalgia syndrome...
Clinical Trials
Supporting Effect of Dronabinol on Behavioral Therapy in Fibromyalgia and Chronic Back Pain
It is known, that a so called "pain memory" usually evolves in chronic pain syndromes which both aggravates the disorder and modifies the patients pain perception. Thus, the principal obje...
Pain Management Techniques for Fibromyalgia
Note: This study is still recruiting participants with fibromyalgia and no longer recruiting healthy participants. Pain management techniques may influence how the brain processes pain an...
Coping Skills Training for Adolescents With Fibromyalgia
Juvenile fibromyalgia is a chronic pain condition that can cause considerable suffering and difficulty in an adolescent's day-to-day activities. The purpose of this study is to determine w...
Efficacy of Acupuncture in the Treatment of Fibromyalgia
Fibromyalgia (FM), one of the most common rheumatic conditions, is a condition of unknown etiology characterized by widespread muscle pain and stiffness. Treatment is generally unsatisfact...
Fibromyalgia is the second most common rheumatic disorder, affecting approximately 8-10 million persons in the U.S., and is characterized by widespread musculoskeletal pain and soft tissue...
Exercise and Behavioral Therapy Trial (EBT).
This trial is a study of Gulf War era veterans who have unexplained chronic medical symptoms such as pain, fatigue, and/or cognitive difficulties. The treatments to be studied, cognitive b...
Tailored Treatments of Fibromyalgia
This study will evaluate the effects of matching treatments to people with fibromyalgia syndrome (FMS) on the basis of their psychosocial and behavioral characteristics. We will look at ho...
Effectiveness of Physical Exercise in Women With Fibromyalgia
Fibromyalgia (FMS) is a syndrome expressed by chronic widespread body pain which leads to reduced physical function and frequent use of health care services. Exercise training is commonly...
There are evidences of functional growth hormone (GH) deficiency, expressed by means of low serum levels of insulin-like growth factor 1 (IGF-1), in a subset of fibromyalgia patients. The...
Web-Based Education to Enhance Fibromyalgia Management
Fibromyalgia (FMS) a condition marked by pain, fatigue, and memory complaints, is considered a chronic condition and is most commonly treated or managed using medications. Previous studie...
Videos
Fibromyalgia: It's Real It's Manageable What You Can Do
The symptoms of fibromyalgia include long-term, body-wide pain and tenderness in the joints, muscles, tendons, and other soft tissues. Dr. Andrew Gross, UCSF...
Medical and Biotech [MESH] Definitions
Fatigue Syndrome, Chronic
A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
Fibromyalgia
A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)
