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Fresh frozen plasma - Biotech, Pharma and Life Science Channel

07:40 EDT 20th June 2013 | BioPortfolio

PubMed Articles [ 7874 Associated PubMed Articles listed on BioPortfolio]

The co-expression of ERβ2 and IL-12Rβ2 is better prognostic factor in non-small-cell lung cancer progression.

Estrogens and IL-12 play a pivotal role in the development and progression of non-small-cell lung cancer (NSCLC); at the same time, estrogen receptor β2 and (interleukin-12 receptor β2)IL-12Rβ2 are...

What is and what should always have been: long-lived plasma cells induced by T cell-independent antigens.

It is well accepted that Ag-induced B cell differentiation often results in the generation of exceptionally long-lived plasma cells. Much of the work supporting this viewpoint stems from studies focus...

Bioanalytical LC-MS/MS of protein-based biopharmaceuticals.

Biotechnology increasingly delivers highly promising protein-based biopharmaceutical candidates to the drug development funnel. For successful biopharmaceutical drug development, reliable bioanalytica...

Development of Pinhole-Free Amorphous Aluminum Oxide Protective Layers for Biomedical Device Applications.

This paper describes synthesis of ultrathin pinhole-free insulating aluminum oxide layers for electronic device protection in corrosive liquid environments, such as phosphate buffered saline (PBS) or...

Determination of antazoline hydrochloride in Beagle dog plasma by HPLC-UV and its application to pharmacokinetics.

In order to evaluate the pharmacokinetics characteristic of antazoline hydrochloride in Beagle dogs, a sensitive and specific HPLC method was developed and validated using phenacetin as the internal s...

Simultaneous determination of bioactive components in essential oil of Xiang-Fu-Si-Wu Formula in Beagle dog plasma by UPLC-MS/MS and its application to pharmacokinetics.

A highly sensitive and rapid ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) has been developed and validated for simultaneous quantification of the three main bioactive c...

Metabolite profiling of astilbin in rat sera using UPLC/MS(E) and impact of its metabolites on immunosuppressive activity.

Astilbin, a natural flavonoid, has been shown to have a selective immunosuppressive activity on activated T lymphocytes. In our previous study, 3'-O-methylastilbin was identified as an active metaboli...

Plasma vitamin d biomarkers and leukocyte telomere length.

Vitamin D may reduce telomere shortening through anti-inflammatory and anti-cell proliferation mechanisms. In the present study, we examined the association between vitamin D and relative leukocyte te...

A rapid and sensitive LC-MS/MS assay for the determination of berbamine in rat plasma with application to preclinical pharmacokinetic study.

Berbamine (BBM), a natural compound from Chinese herb Berberis amurensis, has recently received a great deal of attention due to its anti-leukemia activity. In this study, a rapid and sensitive liquid...

Metabolite identification of a new tyrosine kinase inhibitor, HM781-36B, and a pharmacokinetic study by liquid chromatography/tandem mass spectrometry.

HM781-36B (1-[4-[4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy]-piperidin-1-yl]prop-2-en-1-one hydrochloride) is a new anticancer drug to treat advanced solid tumors in clinical tri...

News Articles [ 2220 Associated News Articles listed on BioPortfolio]

Parents Encourage Kids' Healthy Eating Through Interactive Snacking

IRWINDALE, Calif., June 20, 2013 /PRNewswire-iReach/ -- From the moment that classroom doors swing open in June, floods of school children instantly flee to the nearest park, pool or video game. But...

ProMetic Receives a $4.8 Million Purchase Order from Octapharma

LAVAL, QUEBEC -- (Marketwired) -- 06/20/13 -- ProMetic Life Sciences Inc. (TSX: PLI)(OTCQX: PFSCF), ("ProMetic" or the "Corporation") announced today that it has received a $4.8 million purchase ord...

Quark quartet opens fresh vista on matter

First particle containing four quarks is confirmed.

How Community Resources Could Fill In For Meals on Wheels

The popular Meals on Wheels program has fallen victim to Congress’ clumsy across-the-board spending cuts called sequestration. As a result, local programs are reducing meals deliveries or putting ho...

Care Well: A Fresh Perspective on Travel

Everyone has a different idea of what it means to travel. Consider your own ideas about what travel has meant to you and your family throughout the years. Your photo albums, your Facebook pages, or ju...

Simon & Luke and Gomez Iagmin File Fifth Hepatitis Lawsuit Against Townsend Farms and Costco in Los Angeles

SAN DIEGO, June 19, 2013 /PRNewswire/ -- National food safety law firm of Simon & Luke, with co-counsel Gomez & Iagmin, has filed a fifth California lawsuit stemming from a multi-state Hepatit...

Political Cartoon: 'Intelligent Design?'

Kaiser Health News provides a fresh take on health policy developments with "Intelligent Design?" by Chip Bok. Meanwhile, here is today's health policy haiku: Senate's Bitter Pill  When I bu...

Infographic: The Dawn of a New Era for Airborne Infection Control Technology

There has not been one significant development in infection control since the late nineteenth century. As airborne viruses and bacteria become more resistant to traditional medici...

Zoës Kitchen Announces Sponsorship of Zoë Goes Running to Benefit World Pediatric Project

Fast-Casual Restaurant Launches Charitable Promotion in Support of Super-Runner Zoë Romano; Halfway to Reaching Donation Goal in Just Four Days Zoës...

Qualyst Transporter Solutions and Kaly-Cell Announce the Transporter Certification™ of Human Cryopreserved Hepatocytes

RESEARCH TRIANGLE PARK, N.C., June 19, 2013 /PRNewswire-iReach/ -- Qualyst Transporter Solutions, LLC, has completed its Transporter Certified™ process on two high-quality, plateable cryopreserv...

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Companies [ 71 Associated Companies listed on BioPortfolio]

Zoës Kitchen

Founded in 1995, Zoës Kitchen is a fast-casual restaurant that delivers goodness from the inside out by creating homemade Mediterranean food designed to help you celebrate life...

DOLE Bananas

DOLE is the top-selling banana in America and the world — in both conventional and organic product categories. From its founding by James Drummond Dole, the company has built...

Octapharma

Octapharma, a Swiss-based company, is an independent, global plasma fractionation specialist. Its core business is the development, production and sale of high quality plasma derivatives.From its foun...

CryoXtract Instruments, LLC

CryoXtract develops and commercializes unique automation solutions that allow for the retrieval of multiple frozen samples from a single frozen biosample without exposing the sour...

Dole Food Company, Inc.

Dole Food Company, Inc., with 2008 revenues of $7.6 billion, is the world's largest producer and marketer of high-quality fresh fruit and fresh vegetables. Dole markets a growing...

ConAgra Foods Inc.

ConAgra Foods, Inc., (NYSE: CAG), is one of North America’s leading food companies, with brands in 97 percent of America’s households. Consumers find Banquet, Chef Boyar...

Health Foundation of South Florida

WHO: USDA Regional Administrator Don Arnette; City of Miami Commissioner Wifredo Gort; Florida Department of Children & Families Secretary George Sheldon, (increasing access of SN...

Pinnacle Foods Group LLC

Millions of times a day in more than 85% of American households, consumers reach for Pinnacle Foods brands. We are a leading producer, marketer and distributor of high-quality bra...

Virdante Pharmaceuticals

Virdante Pharmaceuticals is developing safer and more effective drugs for autoimmune and inflammatory diseases. Our products incorporate a proprietary “Sialic Switch” te...

Boston Market

Boston Market Corporation, headquartered in Golden, Colorado, has been giving time back to busy families and individuals for more than 25 years by offering fresh, homestyle meals...

Clinical Trials [ 994 Associated Clinical Trials listed on BioPortfolio]

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

An Open-label, Randomized, Multicenter Phase IIIb Study to Assess the Efficacy, Safety and Tolerance of BERIPLEX® P/N Compared With Plasma for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Subjects Requiring an Urgent Surgical Proced

The purpose of this study is to evaluate efficacy, safety and tolerance of Beriplex® P/N compared with plasma in regard to rapid reversal of coagulopathy induced by vitamin K antagonists...

The Impact of Genotype on Plasma and Cerebral Spinal Fluid Pharmacokinetics of Celecoxib in Children

Background: Celecoxib is effective for reducing postoperative pain in adults. Children use celecoxib more rapidly than adults and require higher doses. Celecoxib is partially metabolized...

TMC435-TiDP16-C112 - Interaction Trial With Antidepressants

The purpose of this study is to investigate the effect of steady-state concentrations of TMC435 150mg q.d. (once a day) on the steady-state pharmacokinetics of escitalopram 10 mg q.d., and...

XELOX III. Xeloda in Combination With Eloxatin for Patients With Advanced or Metastatic Colorectal Cancer

XELOX (Capecitabine and Oxaliplatin) is an effective and convenient regimen for patients with metastatic colorectal cancer. Chronomodulated therapy may reduce toxicity. Patients will be ra...

Changes in Adiposity, Metabolic Measures From Atypicals to Aripiprazole

This proposal aims to use well-validated methodologies such as dual energy x-ray absorptiometry (DEXA), frequently sampled oral glucose tolerance tests (fsOGTTs), and hyperinsulinemic eugl...

Elective Versus Therapeutic Neck Dissection in the Treatment of Early Node Negative Squamous Carcinoma of the Oral Cavity

Cervical metastasis is the single most important prognostic factor in head and neck cancers. Appropriate management of the neck is therefore of paramount importance in the treatment of the...

Prospective, Randomized, Multi-center Clinical Study of Plasma Disc Decompression

The goal of this post-marketing surveillance study is to compare two procedures which are used to treat patients who require a disc decompression procedure. These procedures are: 1) plasma...

Cefepime Pharmacokinetics in Liver Transplant Recipients in an Intensive Care Unit

The purposes of this study are to: I. Characterize the plasma concentration-time profile of cefepime in liver transplant patients to determine the pharmacokinetic parameters in this patie...

The Role of TSH Receptor, PPAR-r, IGF-1R, IGF and Cytokines in Different Stages of Graves’Ophthalmopathy

The exact mechanism of the pathogenesis of Graves’ ophthalmopathy is still unknown. Histopathologically, extraocular muscle inflammation and orbital fat inflammation are two prominent ch...

Medical and Biotech [MESH] Definitions

Hyperuricemia

Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.

Lymphopoiesis

Formation of LYMPHOCYTES and PLASMA CELLS from the lymphoid stem cells which develop from the pluripotent HEMATOPOIETIC STEM CELLS in the BONE MARROW. These lymphoid stem cells differentiate into T-LYMPHOCYTES; B-LYMPHOCYTES; PLASMA CELLS; or NK-cells (KILLER CELLS, NATURAL) depending on the organ or tissues (LYMPHOID TISSUE) to which they migrate.

Integrin Alphavbeta3

An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conserved RGD amino acid sequence and modulates cell adhesion. Integrin alphavbeta3 is highly expressed in OSTEOCLASTS where it may play role in BONE RESORPTION. It is also abundant in vascular smooth muscle and endothelial cells, and in some tumor cells, where it is involved in angiogenesis and cell migration. Although often referred to as the vitronectin receptor there is more than one receptor for vitronectin (RECEPTORS, VITRONECTIN).

5-alpha-dihydroprogesterone

A biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (ALLOPREGNANOLONE), a neuroactive steroid that binds with GABA(A) RECEPTOR.

Aeromonadaceae

A family of gram-negative facultatively anaerobic bacteria, ubiquitous in fresh and brackish water, and associated with GASTROINTESTINAL DISEASES.

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