Frontotemporal Dementia - Biotech, Pharma and Life Science Channel
PubMed Articles
ABSTRACT Background: Cost of informal care constitutes an important component of total dementia care cost. It also reflects resource utilization by patients and caregivers. We aim to quantify the info...
ABSTRACT Background: The prognostic value of subjective memory complaints (SMCs) in the diagnosis of dementia of the Alzheimer's type is unclear. While some studies have found an association between S...
TARDBP mutation p.Ile383Val associated with semantic dementia and complex proteinopathy.
Neurology in Argentina emerged toward the end of the 19th century, following the origin of the specialty in Europe. Its development can be divided into 3 periods. The first is the specialty of neurolo...
Nonmelanoma skin cancer is associated with reduced Alzheimer disease risk.
OBJECTIVE: To explore the association of nonmelanoma skin cancer (NMSC) and Alzheimer disease (AD) in the Einstein Aging Study, an epidemiologic study of aging in New York City. METHODS: Community-res...
Interrater reliability of the new criteria for behavioral variant frontotemporal dementia.
OBJECTIVE: To evaluate the interrater reliability of the new International Behavioural Variant FTD Criteria Consortium (FTDC) criteria for behavioral variant frontotemporal dementia (bvFTD). METHODS:...
Economics of neurology 101: The dismal science meets the dismal prognosis.
In the coming decades, we are faced with a massive demographic shift: the nation as a whole is getting older, by leaps and bounds. The number of persons in the oldest demographic, ages 85 and older, i...
The aim is to investigate the effect of a comprehensive physical and psychosocial approach on functional outcome and cerebral glucose metabolism in poststroke vascular dementia (PSVaD). Ten PSVaD pati...
ABSTRACT Background: We studied the suitability of The Consortium to Establish a Registry for Alzheimer's Disease Neuropsychological Battery (CERAD-NB) total score for monitoring Alzheimer's disease (...
INTRODUCTION: Direct correlation between neuropathological findings and postmortem neuromelanin MR imaging (NmMRI) was performed in the substantia nigra pars compacta (SNc) to clarify the pathological...
News Articles
EEG Diagnostic Specialist MentisCura Joins Stockholm Brain Institute Consortium
MentisCura Diagnostics will contribute as a partner and board member of the Stockholm Brain Institute, a consortium for cognitive and computational neuroscience, led by the Karoli...
Nurses offered £150,000 prize for dementia innovation
NHS England is inviting staff on the frontline of dementia care to showcase service innovations for the chance to win up to £150,000, and see their idea rolled out across the country.
Adult day services for dementia patients provide stress relief to family caregivers
(Penn State) Family caregivers of older adults with dementia are less stressed and their moods are improved on days when dementia patients receive adult day services, according to Penn State researche...
Nordion, Navidea Biopharmaceuticals ink contract manufacturing agreement
Nordion, a provider of products and services to the global health science market, has signed a contract manufacturing agreement with Navidea Biopharmaceuticals, a biopharmaceutical company focused on...
MindStart Offers New Resource for Incorporating Horticulture Therapy into Dementia Care
Horticulture therapy can provide meaningful and stimulating activities for people receiving dementia care. MindStart announces the release of a new product, A Calendar Year of Horticulture Therapy boo...
Blood-Brain Barrier Integrity Suffers Days After Ischemic Stroke Leading To Serious Complications
While the effects of acute stroke have been widely studied, brain damage during the subacute phase of stroke has been a neglected area of research. Now, a new study by the University of South Florida...
Mediterranean Diet Offers Cognitive Boost To The Aging Brain
Peter Suciu for redOrbit.com – Your Universe Online The Mayo Clinic has called the Mediterranean diet a heart-healthy eating plan as it combines elements of Mediterranean-style cooking with a spla...
B vitamins could delay dementia
(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now...
This book is the culmination of over 50 years of experience with the world of dementia. The book’s six sections explore topics basic to caregivers developing their own techniques and approaches to m...
Claims vitamin B prevents Alzheimer's are unproven
'Should you be taking vitamin B to protect against Alzheimer's?,' asks the Daily Mail. Its question is prompted by new research into whether a daily dose of vitamin B could reduce the loss of brain t...
Events
None
Companies
HopeHealth, formerly known as Hospice & Palliative Care of Cape Cod, has been enhancing the quality of life for people experiencing serious illness and loss for more than thirty y...
Avid Radiopharmaceuticals, Inc.
Avid Radiopharmaceuticals is a leader in the development of molecular imaging products with the potential for earlier and more effective detection, diagnosis and monitoring of maj...
For more than a decade, Potomac Homes has made it possible for those with Alzheimerâs disease or dementia-related illnesses to enjoy the benefits of full-time professional ca...
Senior Resource Group, LLC (SRG) has been a leader in providing distinctive retirement living since 1988. SRG develops, owns and operates independent living, assisted living and A...
Homewatch CareGivers International
Homewatch CareGivers International provides home care and personal assistance that individuals who are aging, disabled and rehabilitating need to remain in their homes. Since its...
Emeritus Corporation is a national provider of assisted living and Alzheimer's and related dementia care services to seniors. Emeritus is one of the largest and most experienced o...
Janssen Alzheimer Immunotherapy
Alzheimer's disease (AD), the most common form of dementia, is a fatal, degenerative brain disease that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate a...
Clinical Trials
Music Therapy in Methodist Homes: a Study Investigating the Impact of a Music Therapy Programme
The study is a cluster randomised control trial, which aims to investigate the effectiveness of music therapy in minimising Behavioural and Psychological Symptoms of Dementia (BPSD) in old...
An Efficacy and Safety Study of Galantamine for the Treatment of Patients With Alzheimer's Disease
The purpose of this study is to evaluate the efficacy and safety of two fixed doses (16mg/day and 24mg/day) of galantamine (a drug for treating dementia) versus placebo for the treatment o...
Deep brain stimulation has been developed as a substitute for the classical lesioning methods previously used in stereotactic and functional neurosurgery. Recent, anecdotal cases reports...
Donepezil Treatment of Psychotic Symptoms in Dementia Patients
Conventional psychotropic medications may be used to treat behavioral disturbances and psychotic symptoms in patients with dementia and they are the drugs of choice for treating delusions...
Objectives: The objective of this study will be to determine the safety, tolerability, drug blood levels, and efficacy of each of three doses of NS 2330 (Tesofensine) given once daily com...
Cognitive Training in the Elderly
Background: The aging of the population has lead to a significant increase in the number of older people suffering from cognitive impairment and dementia. The present lack of effective dr...
Cohorts and Collections: Clinical and Genetic Study of Parkinson's Disease and Epilepsies
The DNA and Cell Bank of Instituts Federatifs de Recherche (IFR) of Neurosciences has been running for the last 15 years at the Institut National de la Santé Et de la Recherche Médicale...
Double Blind Trial of DC Polarization in FTD
This project is designed to test how direct current (DC) electrical polarization of the brain affects language and behavior in patients with frontotemporal dementia (FTD). FTD is the secon...
Relationship of Dopamine to Cognitive Function in Parkinson's Disease
This study will examine how the brain chemical dopamine affects memory, reasoning, and other thought processes in people with Parkinson's disease with and without dementia and in healthy c...
Treatment Study of Frontotemporal Dementia
Objectives. The proposed clinical study has two goals: First, to assess the efficacy of a central nervous system stimulant and an atypical antipsychotic in treating the behavioral symptom...
Videos
Frontotemporal Dementia
Dementia is a problem of the elderly, right? Generally that's true. But there is one form of the disease that can strike people when they are very young, in ...
Medical and Biotech [MESH] Definitions
Leukoaraiosis
Non-specific white matter changes in the BRAIN, often seen after age 65. Changes include loss of AXONS; MYELIN pallor, GLIOSIS, loss of ependymal cells, and enlarged perivascular spaces. Leukoaraiosis is a risk factor for DEMENTIA and CEREBROVASCULAR DISORDERS.
Marchiafava-bignami Disease
A neurodegenerative condition that is characterized by demyelination or necrosis of the CORPUS CALLOSUM. Symptoms include DEPRESSION; PARANOIA; DEMENTIA; SEIZURES; and ATAXIA which can progress to COMA and death in a few months. Marchiafava-Bignami syndrome is seen often in alcoholics but has been found in non-alcoholics as well.
Diffuse Neurofibrillary Tangles With Calcification
A form of presenile DEMENTIA characterized by cortical dementia, NEUROFIBRILLARY TANGLES without SENILE PLAQUES, Fahr's type CALCINOSIS, and ATROPHY in frontotemporal or TEMPORAL LOBE.
Frontotemporal Lobar Degeneration
Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.
Tdp-43 Proteinopathies
Diseases characterized by the presence of abnormally phosphorylated, ubiquitinated, and cleaved DNA-binding protein TDP-43 in affected brain and spinal cord. Inclusions of the pathologic protein in neurons and glia, without the presence of AMYLOID, is the major feature of these conditions, thus making these proteinopathies distinct from most other neurogenerative disorders in which protein misfolding leads to brain amyloidosis. Both frontotemporal lobar degeneration and AMYOTROPHIC LATERAL SCLEROSIS exhibit this common method of pathogenesis and thus they may represent two extremes of a continuous clinicopathological spectrum of one disease.
